JP2004502462A5 - - Google Patents

Info

Publication number

JP2004502462A5

JP2004502462A5 JP2002509509A JP2002509509A JP2004502462A5 JP 2004502462 A5 JP2004502462 A5 JP 2004502462A5 JP 2002509509 A JP2002509509 A JP 2002509509A JP 2002509509 A JP2002509509 A JP 2002509509A JP 2004502462 A5 JP2004502462 A5 JP 2004502462A5

Authority

JP

Japan

Prior art keywords

bioprobe

moiety

protein

nucleic acid

biomaterial

Prior art date

2001-06-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 238000000034 method Methods 0.000 claims description 16
• 239000012620 biological material Substances 0.000 claims description 14
• 238000001962 electrophoresis Methods 0.000 claims description 8
• 238000004720 dielectrophoresis Methods 0.000 claims description 7
• 230000027455 binding Effects 0.000 claims description 6
• 230000009870 specific binding Effects 0.000 claims description 5
• 238000001514 detection method Methods 0.000 claims description 3
• 230000005684 electric field Effects 0.000 claims description 3
• 238000000746 purification Methods 0.000 claims description 3
• 102000004169 proteins and genes Human genes 0.000 claims 14
• 108090000623 proteins and genes Proteins 0.000 claims 14
• 108020004707 nucleic acids Proteins 0.000 claims 13
• 102000039446 nucleic acids Human genes 0.000 claims 13
• 150000007523 nucleic acids Chemical class 0.000 claims 13
• 108090000765 processed proteins & peptides Proteins 0.000 claims 11
• 241000894007 species Species 0.000 claims 10
• 150000002632 lipids Chemical class 0.000 claims 7
• 102000005962 receptors Human genes 0.000 claims 7
• 108020003175 receptors Proteins 0.000 claims 7
• 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 6
• NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 6
• 108020004414 DNA Proteins 0.000 claims 5
• 150000001720 carbohydrates Chemical class 0.000 claims 5
• 235000014633 carbohydrates Nutrition 0.000 claims 5
• 150000002894 organic compounds Chemical class 0.000 claims 5
• 102000053602 DNA Human genes 0.000 claims 4
• 241000700605 Viruses Species 0.000 claims 4
• 210000004027 cell Anatomy 0.000 claims 4
• 125000005647 linker group Chemical group 0.000 claims 4
• 210000003463 organelle Anatomy 0.000 claims 4
• 210000001519 tissue Anatomy 0.000 claims 4
• 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 3
• 102000009024 Epidermal Growth Factor Human genes 0.000 claims 3
• 102000004877 Insulin Human genes 0.000 claims 3
• 108090001061 Insulin Proteins 0.000 claims 3
• 108050001286 Somatostatin Receptor Proteins 0.000 claims 3
• 102000011096 Somatostatin receptor Human genes 0.000 claims 3
• 102000004338 Transferrin Human genes 0.000 claims 3
• 108090000901 Transferrin Proteins 0.000 claims 3
• 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 3
• 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 3
• 102100040247 Tumor necrosis factor Human genes 0.000 claims 3
• 229940125396 insulin Drugs 0.000 claims 3
• 239000003446 ligand Substances 0.000 claims 3
• 102000004196 processed proteins & peptides Human genes 0.000 claims 3
• 239000012581 transferrin Substances 0.000 claims 3
• 108091027305 Heteroduplex Proteins 0.000 claims 2
• 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
• 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 2
• 108020004682 Single-Stranded DNA Proteins 0.000 claims 2
• 239000000463 material Substances 0.000 claims 2
• RXWNCPJZOCPEPQ-NVWDDTSBSA-N puromycin Chemical compound C1=CC(OC)=CC=C1C[C@H](N)C(=O)N[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(=C3N=C2)N(C)C)O[C@@H]1CO RXWNCPJZOCPEPQ-NVWDDTSBSA-N 0.000 claims 2
• 239000000126 substance Substances 0.000 claims 2
• 238000000018 DNA microarray Methods 0.000 claims 1
• 229930182558 Sterol Natural products 0.000 claims 1
• 150000001412 amines Chemical group 0.000 claims 1
• 150000003868 ammonium compounds Chemical group 0.000 claims 1
• 150000001875 compounds Chemical class 0.000 claims 1
• 235000014113 dietary fatty acids Nutrition 0.000 claims 1
• 230000005611 electricity Effects 0.000 claims 1
• 229930195729 fatty acid Natural products 0.000 claims 1
• 239000000194 fatty acid Substances 0.000 claims 1
• 150000004665 fatty acids Chemical class 0.000 claims 1
• 239000007850 fluorescent dye Substances 0.000 claims 1
• 238000001997 free-flow electrophoresis Methods 0.000 claims 1
• 230000002068 genetic effect Effects 0.000 claims 1
• 150000002484 inorganic compounds Chemical class 0.000 claims 1
• 229910010272 inorganic material Inorganic materials 0.000 claims 1
• 239000002773 nucleotide Substances 0.000 claims 1
• 125000003729 nucleotide group Chemical group 0.000 claims 1
• 150000007524 organic acids Chemical class 0.000 claims 1
• 150000007530 organic bases Chemical class 0.000 claims 1
• 108020001775 protein parts Proteins 0.000 claims 1
• 229950010131 puromycin Drugs 0.000 claims 1
• 230000002285 radioactive effect Effects 0.000 claims 1
• 150000003432 sterols Chemical class 0.000 claims 1
• 235000003702 sterols Nutrition 0.000 claims 1