JP2004285076A5 - - Google Patents
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- Publication number
- JP2004285076A5 JP2004285076A5 JP2004155357A JP2004155357A JP2004285076A5 JP 2004285076 A5 JP2004285076 A5 JP 2004285076A5 JP 2004155357 A JP2004155357 A JP 2004155357A JP 2004155357 A JP2004155357 A JP 2004155357A JP 2004285076 A5 JP2004285076 A5 JP 2004285076A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89651292A | 1992-06-09 | 1992-06-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6501713A Division JPH08507916A (ja) | 1992-06-09 | 1993-06-09 | Ｍ−ｃｓｆの結晶化 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004285076A JP2004285076A (ja) | 2004-10-14 |
| JP2004285076A5 true JP2004285076A5 (enExample) | 2005-08-11 |
Family
ID=25406334
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6501713A Withdrawn JPH08507916A (ja) | 1992-06-09 | 1993-06-09 | Ｍ−ｃｓｆの結晶化 |
| JP2004155357A Withdrawn JP2004285076A (ja) | 1992-06-09 | 2004-05-25 | Ｍ−ｃｓｆの結晶化 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6501713A Withdrawn JPH08507916A (ja) | 1992-06-09 | 1993-06-09 | Ｍ−ｃｓｆの結晶化 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5866114A (enExample) |
| EP (2) | EP0955365A3 (enExample) |
| JP (2) | JPH08507916A (enExample) |
| AT (1) | ATE195553T1 (enExample) |
| CA (1) | CA2137793C (enExample) |
| DE (1) | DE69329247T2 (enExample) |
| WO (1) | WO1993025687A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5581476A (en) * | 1993-01-28 | 1996-12-03 | Amgen Inc. | Computer-based methods and articles of manufacture for preparing G-CSF analogs |
| US6372219B1 (en) * | 1996-03-14 | 2002-04-16 | Univ Illinois | Parasite-derived anti-inflammatory immunomodulatory protein |
| AU1759501A (en) * | 1999-11-08 | 2001-06-06 | Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The | Method of treating a viral infection using antagonists of macrophage colony stimulating factor |
| DE60217066T4 (de) | 2001-02-09 | 2010-07-01 | Genentech, Inc., South San Francisco | Kristallisierung von igf-1 |
| US7247618B2 (en) * | 2001-04-30 | 2007-07-24 | Tripathi Rajavashisth | Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling |
| KR100961859B1 (ko) | 2001-07-11 | 2010-06-09 | 맥시겐 홀딩스 엘티디 | 지-씨에스에프 접합체 |
| US7563595B2 (en) * | 2002-11-08 | 2009-07-21 | University Of South Florida | Nucleic acids encoding functional splice variants of the α7 nicotinic acetylcholine receptor subunit and methods for producing the encoded proteins |
| AR045563A1 (es) * | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| US20050124008A1 (en) * | 2003-12-05 | 2005-06-09 | Kauvar Lawrence M. | Homogeneous competition assays |
| EP1706137A2 (en) * | 2004-01-21 | 2006-10-04 | Chiron Corporation | M-csf muteins and uses thereof |
| US20060094081A1 (en) * | 2004-10-22 | 2006-05-04 | Carsten Schubert | Crystal structure of the c-fms kinase domain: applications and use of heterologous substitutions of kinase insert domains for crystallization |
| KR20080027291A (ko) | 2005-06-01 | 2008-03-26 | 맥시겐 홀딩스 엘티디 | 피이지화된 지-씨에스에프 폴리펩타이드 및 그 제조방법 |
| KR100970770B1 (ko) | 2008-02-12 | 2010-07-16 | 한국기초과학지원연구원 | 결정성 재조합 단백질 휴먼 에스피오티 및 이의 결정화방법 |
| US8080246B2 (en) * | 2008-11-26 | 2011-12-20 | Five Prime Therapeutics, Inc. | Colony stimulating factor 1 receptor (CSF1R) extracellular domain fusion molecules |
| US8183207B2 (en) * | 2008-11-26 | 2012-05-22 | Five Prime Therapeutics, Inc. | Treatment of osteolytic disorders and cancer using CSF1R extracellular domain fusion molecules |
| AR075899A1 (es) * | 2009-03-20 | 2011-05-04 | Onyx Therapeutics Inc | Tripeptidos epoxicetonas cristalinos inhibidores de proteasa |
| DK2510010T3 (en) | 2009-12-10 | 2015-12-14 | Hoffmann La Roche | Antibodies that bind to human CSF1R extracellular domain 4 and their use |
| RU2617971C2 (ru) | 2010-03-05 | 2017-04-28 | Ф.Хоффманн-Ля Рош Аг | Антитела против csf-1r человека и их применение |
| CN102918061B (zh) | 2010-03-05 | 2016-06-08 | 霍夫曼-拉罗奇有限公司 | 针对人csf-1r的抗体及其用途 |
| EP3943154A1 (en) | 2010-05-04 | 2022-01-26 | Five Prime Therapeutics, Inc. | Antibodies that bind csf1r |
| US20140378537A1 (en) | 2011-09-09 | 2014-12-25 | Genentech, Inc. | Treatment of th17 mediated inflammatory diseases |
| MX356337B (es) | 2011-12-15 | 2018-05-23 | Hoffmann La Roche | Anticuerpos contra csf-1r humano y sus usos. |
| US20130302322A1 (en) | 2012-05-11 | 2013-11-14 | Five Prime Therapeutics, Inc. | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
| CN107759690A (zh) | 2012-08-31 | 2018-03-06 | 戊瑞治疗有限公司 | 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法 |
| AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
| AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
| EP3157957A1 (en) | 2014-06-23 | 2017-04-26 | Five Prime Therapeutics, Inc. | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
| HUE054012T2 (hu) | 2014-10-29 | 2021-08-30 | Five Prime Therapeutics Inc | Kombinációs terápia rák ellen |
| US10040858B2 (en) | 2014-12-22 | 2018-08-07 | Five Prime Therapeutics, Inc. | Anti-CSF1R antibodies for treating PVNS |
| CA2980460A1 (en) | 2015-04-13 | 2016-10-20 | Five Prime Therapeutics, Inc. | Combination therapy for cancer |
| EP3504239B1 (en) | 2016-08-25 | 2024-05-29 | F. Hoffmann-La Roche AG | Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent |
| CN110072553B (zh) | 2016-12-22 | 2023-09-15 | 豪夫迈·罗氏有限公司 | 在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗 |
| CN106843149A (zh) * | 2017-03-28 | 2017-06-13 | 吴小江 | 一种机械零固件产品加工系统 |
| JP2020535119A (ja) | 2017-09-13 | 2020-12-03 | ファイヴ プライム セラピューティクス インク | 膵臓がんの抗ｃｓｆ１ｒおよび抗ｐｄ−１抗体組合せ併用療法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4672108A (en) * | 1981-12-07 | 1987-06-09 | Hoffmann-La Roche Inc. | Crystalline human leukocyte interferon |
| US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| US4966911A (en) * | 1984-11-20 | 1990-10-30 | Washington Research Foundation | Immunoregulatory agents |
| US4847201A (en) * | 1985-02-05 | 1989-07-11 | Cetus Corporation | DNA encoding for CSF-1 and accompanying recombinant systems |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| JPS62106000A (ja) * | 1985-10-30 | 1987-05-16 | Fujitsu Ltd | 生体高分子結晶自動作製装置 |
| US4908773A (en) * | 1987-04-06 | 1990-03-13 | Genex Corporation | Computer designed stabilized proteins and method for producing same |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4881175A (en) * | 1986-09-02 | 1989-11-14 | Genex Corporation | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US5032676A (en) | 1986-10-14 | 1991-07-16 | Immunex Corporation | Nonglycosylated analogs of human colony stimulating factors |
| JP2644794B2 (ja) * | 1986-10-24 | 1997-08-25 | カイロン コーポレイション | 新規な型のコロニー刺激因子―１ |
| IL86090A (en) * | 1987-04-16 | 1993-03-15 | Cetus Oncology Corp | Production of purified, biologically active, bacterially produced recombinant human csf-1 |
| US4929700A (en) * | 1987-04-16 | 1990-05-29 | Cetus Corporation | Production of purified, biologically active, bacterially produced recombinant human CSF-1 |
| US4833233A (en) * | 1987-08-20 | 1989-05-23 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Human serum albumin crystals and method of preparation |
| EP0344796B1 (en) * | 1988-06-03 | 1994-09-21 | Chugai Seiyaku Kabushiki Kaisha | Crystalline human granulocyte colony stimulating factor and process for preparing the same |
| US5109119A (en) * | 1989-06-06 | 1992-04-28 | Schering Corporation | Crystalline r-h-gm-csf and method |
| IE66494B1 (en) * | 1989-09-26 | 1996-01-10 | Immunex Corp | Granulocyte-colony stimulating factor receptors |
| ES2060360T3 (es) * | 1989-12-21 | 1994-11-16 | Novo Nordisk As | Metodo para la cristalizacion de enzimas. |
| ATE196548T1 (de) * | 1991-05-10 | 2000-10-15 | Genentech Inc | Auswählen von agonisten und antagonisten von liganden |
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1993
- 1993-06-09 JP JP6501713A patent/JPH08507916A/ja not_active Withdrawn
- 1993-06-09 AT AT93915279T patent/ATE195553T1/de not_active IP Right Cessation
- 1993-06-09 DE DE69329247T patent/DE69329247T2/de not_active Expired - Lifetime
- 1993-06-09 US US08/351,292 patent/US5866114A/en not_active Expired - Lifetime
- 1993-06-09 EP EP99108304A patent/EP0955365A3/en not_active Withdrawn
- 1993-06-09 CA CA002137793A patent/CA2137793C/en not_active Expired - Lifetime
- 1993-06-09 EP EP93915279A patent/EP0668914B1/en not_active Expired - Lifetime
- 1993-06-09 WO PCT/US1993/005548 patent/WO1993025687A1/en not_active Ceased
-
1995
- 1995-06-05 US US08/462,794 patent/US6184354B1/en not_active Expired - Lifetime
-
2004
- 2004-05-25 JP JP2004155357A patent/JP2004285076A/ja not_active Withdrawn