|
US6390821B1
(en)
*
|
1997-02-07 |
2002-05-21 |
Princeton University |
Engineered protein kinases which can utilize modified nucleotide triphosphate substrates
|
|
US6162613A
(en)
*
|
1998-02-18 |
2000-12-19 |
Vertex Pharmaceuticals, Inc. |
Methods for designing inhibitors of serine/threonine-kinases and tyrosine kinases
|
|
US7383135B1
(en)
|
1998-05-04 |
2008-06-03 |
Vertex Pharmaceuticals Incorporated |
Methods of designing inhibitors for JNK kinases
|
|
US6610483B1
(en)
*
|
1999-07-23 |
2003-08-26 |
Princeton University |
Methods for identifying cellular responses attributable to signaling molecule inhibition and inhibitors thereof
|
|
DE10024174A1
(de)
*
|
2000-05-17 |
2001-11-29 |
Gsf Forschungszentrum Umwelt |
Verfahren zum Selektieren von Inhibitoren für Enzyme
|
|
US7792645B2
(en)
*
|
2000-08-30 |
2010-09-07 |
The Salk Institute For Biological Studies |
Three-dimensional structure of chalcone isomerase and methods of use thereof
|
|
WO2002057418A2
(en)
*
|
2000-12-15 |
2002-07-25 |
The Salk Institute For Biological Studies |
Methods of producing polyketide synthase mutants and compositions and uses thereof
|
|
CA2444882A1
(en)
|
2001-04-30 |
2002-11-07 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of gsk-3 and crystal structures of gsk-3.beta. protein and protein complexes
|
|
US20060263800A1
(en)
*
|
2001-11-01 |
2006-11-23 |
Princeton University |
Engineered protein kinases which can utilize modified nucleotide triphosphate substrates
|
|
WO2003105723A2
(en)
*
|
2002-06-14 |
2003-12-24 |
The Salk Institute For Biological Studies |
Mutant plant caffeic acid/5-hydroxyferulic acid 3/5-0-methyltransferases (comt), methods for preparation and use thereof
|
|
AU2003267145A1
(en)
*
|
2002-09-13 |
2004-04-30 |
Irm, Llc |
Highly specific modulators of gtpases for target validation
|
|
EP1572097A4
(en)
*
|
2002-09-30 |
2010-02-17 |
Smithkline Beecham Corp |
NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF INFECTIONS WITH THE HEPATITIS C-VIRUS
|
|
US7429596B2
(en)
*
|
2003-06-20 |
2008-09-30 |
The Regents Of The University Of California |
1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof
|
|
DE602004004278T2
(de)
|
2003-08-15 |
2007-10-31 |
Merck & Co, Inc. |
4-cycloalkylaminopyrazolopyrimidin als nmda/nr2b-antagonisten
|
|
ES2317313T3
(es)
*
|
2004-10-19 |
2009-04-16 |
Krka, Tovarna Zdravil, D.D., Novo Mesto |
Composicion farmaceutica solida que comprende clorhidrato de donepezilo.
|
|
EP1831225A2
(en)
*
|
2004-11-19 |
2007-09-12 |
The Regents of the University of California |
Anti-inflammatory pyrazolopyrimidines
|
|
EP1946106A4
(en)
*
|
2005-10-13 |
2009-04-08 |
Activesite Pharmaceuticals |
METHOD FOR IDENTIFYING INHIBITORS OF ENZYME ACTIVITY
|
|
WO2007114926A2
(en)
|
2006-04-04 |
2007-10-11 |
The Regents Of The University Of California |
Kinase antagonists
|
|
US7890417B2
(en)
*
|
2007-01-31 |
2011-02-15 |
Bids Trading, L.P. |
Electronic block trading system and method of operation
|
|
GB2467670B
(en)
*
|
2007-10-04 |
2012-08-01 |
Intellikine Inc |
Chemical entities and therapeutic uses thereof
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
MX2010007419A
(es)
|
2008-01-04 |
2010-11-12 |
Intellikine Inc |
Ciertas entidades quimicas, composiciones y metodos.
|
|
WO2009102867A1
(en)
*
|
2008-02-12 |
2009-08-20 |
Bids Trading, L.P. |
Real-time portfolio balancing and/or optimization system and method
|
|
US8993580B2
(en)
*
|
2008-03-14 |
2015-03-31 |
Intellikine Llc |
Benzothiazole kinase inhibitors and methods of use
|
|
EP2252293B1
(en)
|
2008-03-14 |
2018-06-27 |
Intellikine, LLC |
Kinase inhibitors and methods of use
|
|
US20110224223A1
(en)
*
|
2008-07-08 |
2011-09-15 |
The Regents Of The University Of California, A California Corporation |
MTOR Modulators and Uses Thereof
|
|
BRPI0915231A2
(pt)
|
2008-07-08 |
2018-06-12 |
Intellikine Inc |
compostos inibidores de quinase e métodos de uso
|
|
CA2738429C
(en)
|
2008-09-26 |
2016-10-25 |
Intellikine, Inc. |
Heterocyclic kinase inhibitors
|
|
EP2358720B1
(en)
|
2008-10-16 |
2016-03-02 |
The Regents of The University of California |
Fused ring heteroaryl kinase inhibitors
|
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
JP5789252B2
(ja)
|
2009-05-07 |
2015-10-07 |
インテリカイン， エルエルシー |
複素環式化合物およびその使用
|
|
NZ598220A
(en)
|
2009-08-17 |
2014-02-28 |
Intellikine Llc |
Heterocyclic compounds and uses thereof
|
|
WO2011047384A2
(en)
|
2009-10-16 |
2011-04-21 |
The Regents Of The University Of California |
Methods of inhibiting ire1
|
|
CA2799579A1
(en)
|
2010-05-21 |
2011-11-24 |
Intellikine, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
|
JP2013545749A
(ja)
|
2010-11-10 |
2013-12-26 |
インフィニティー ファーマシューティカルズ， インコーポレイテッド |
複素環化合物及びその使用
|
|
ES2637113T3
(es)
|
2011-01-10 |
2017-10-10 |
Infinity Pharmaceuticals, Inc. |
Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas
|
|
US9295673B2
(en)
|
2011-02-23 |
2016-03-29 |
Intellikine Llc |
Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof
|
|
HK1198443A1
(en)
|
2011-07-19 |
2015-04-24 |
无限药品股份有限公司 |
Heterocyclic compounds and uses thereof
|
|
AR088218A1
(es)
|
2011-07-19 |
2014-05-21 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos utiles como inhibidores de pi3k
|
|
MX2014002542A
(es)
|
2011-08-29 |
2014-07-09 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y usos de los mismos.
|
|
CA2846496C
(en)
|
2011-09-02 |
2020-07-14 |
The Regents Of The University Of California |
Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
|
JP2015532287A
(ja)
|
2012-09-26 |
2015-11-09 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア |
Ｉｒｅ１の調節
|
|
AU2013337717B2
(en)
|
2012-11-01 |
2018-10-25 |
Infinity Pharmaceuticals, Inc. |
Treatment of cancers using PI3 kinase isoform modulators
|
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
|
WO2014153509A1
(en)
|
2013-03-22 |
2014-09-25 |
Millennium Pharmaceuticals, Inc. |
Combination of catalytic mtorc 1/2 inhibitors and selective inhibitors of aurora a kinase
|
|
US10769725B1
(en)
|
2013-06-05 |
2020-09-08 |
Bids Trading, L.P. |
System and methods for optimizing the effectiveness of interaction between participants in an electronic trading environment
|
|
PT3052485T
(pt)
|
2013-10-04 |
2021-10-22 |
Infinity Pharmaceuticals Inc |
Compostos heterocíclicos e suas utilizações
|
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
MX382033B
(es)
|
2014-03-19 |
2025-03-13 |
Infinity Pharmaceuticals Inc |
Compuestos heterocíclicos para utilizarlos en el tratamiento de trastornos mediados por pi3k-gamma.
|
|
WO2015160975A2
(en)
|
2014-04-16 |
2015-10-22 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
WO2016054491A1
(en)
|
2014-10-03 |
2016-04-07 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2017048702A1
(en)
|
2015-09-14 |
2017-03-23 |
Infinity Pharmaceuticals, Inc. |
Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
|
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
|
WO2017214269A1
(en)
|
2016-06-08 |
2017-12-14 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
SG11201811237WA
(en)
|
2016-06-24 |
2019-01-30 |
Infinity Pharmaceuticals Inc |
Combination therapies
|
|
CA3102279A1
(en)
|
2018-06-01 |
2019-12-05 |
Cornell University |
Combination therapy for pi3k-associated disease or disorder
|
|
US20230121698A1
(en)
*
|
2019-12-23 |
2023-04-20 |
Sanford Burnham Prebys Medical Discovery Institute |
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (enpp1) modulators and uses thereof
|
|
US20230417751A1
(en)
*
|
2021-05-13 |
2023-12-28 |
Texas Tech University System |
Analysis of protein kinases in live cells
|
|
US12215108B2
(en)
|
2022-01-10 |
2025-02-04 |
Southern Research Institute |
Development of potential antidotes for arsenicals
|