JP2003528887A5 - - Google Patents
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- Publication number
- JP2003528887A5 JP2003528887A5 JP2001571713A JP2001571713A JP2003528887A5 JP 2003528887 A5 JP2003528887 A5 JP 2003528887A5 JP 2001571713 A JP2001571713 A JP 2001571713A JP 2001571713 A JP2001571713 A JP 2001571713A JP 2003528887 A5 JP2003528887 A5 JP 2003528887A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine according
- peptide
- human cytomegalovirus
- vaccine
- modulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229960005486 vaccine Drugs 0.000 description 14
- 108090000765 processed proteins & peptides Proteins 0.000 description 9
- 241000701024 Human betaherpesvirus 5 Species 0.000 description 5
- 239000002671 adjuvant Substances 0.000 description 5
- 208000024697 human cytomegalovirus infection Diseases 0.000 description 5
- 230000028993 immune response Effects 0.000 description 5
- 239000008194 pharmaceutical composition Substances 0.000 description 5
- 210000000612 antigen-presenting cell Anatomy 0.000 description 3
- 229940030156 cell vaccine Drugs 0.000 description 3
- 241000700605 Viruses Species 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229940126580 vector vaccine Drugs 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/534,639 | 2000-03-27 | ||
| US09/534,639 US6251399B1 (en) | 1996-11-12 | 2000-03-27 | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| US09/692,170 | 2000-10-20 | ||
| US09/692,170 US6562345B1 (en) | 1996-11-12 | 2000-10-20 | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| PCT/US2001/008576 WO2001072782A2 (en) | 2000-03-27 | 2001-03-16 | Immuno-reactive peptide ctl epitopes of human cytomegalovirus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011243962A Division JP5731952B2 (ja) | 2000-03-27 | 2011-11-07 | ヒトサイトメガロウイルスの免疫ー反応性ペプチドctlエピトープ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003528887A JP2003528887A (ja) | 2003-09-30 |
| JP2003528887A5 true JP2003528887A5 (https=) | 2007-06-28 |
| JP5602332B2 JP5602332B2 (ja) | 2014-10-08 |
Family
ID=27064538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001571713A Expired - Lifetime JP5602332B2 (ja) | 2000-03-27 | 2001-03-16 | ヒトサイトメガロウイルスの免疫ー反応性ペプチドctlエピトープ |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US6562345B1 (https=) |
| EP (1) | EP1268529A2 (https=) |
| JP (1) | JP5602332B2 (https=) |
| AU (2) | AU2001249243B2 (https=) |
| CA (1) | CA2401638C (https=) |
| WO (1) | WO2001072782A2 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7935675B1 (en) * | 1994-07-15 | 2011-05-03 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US20040171028A1 (en) * | 1996-06-06 | 2004-09-02 | Baker Brenda F. | Phosphorous-linked oligomeric compounds and their use in gene modulation |
| US6632435B1 (en) * | 1999-10-20 | 2003-10-14 | City Of Hope | CTL epitope analogs |
| US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| US8022190B2 (en) | 2001-06-19 | 2011-09-20 | Technion Research & Development Foundation Ltd. | Immuno-molecules containing viral proteins, compositions thereof and methods of using |
| AUPR593101A0 (en) | 2001-06-26 | 2001-07-19 | Council Of The Queensland Institute Of Medical Research, The | Cytomegalovirus t cell epitopes |
| WO2003073097A2 (en) * | 2002-02-28 | 2003-09-04 | Intercell Ag | Methods for isolating ligands e.g. t cell epitopes |
| US8895020B2 (en) * | 2002-04-19 | 2014-11-25 | Washington University | Single chain trimers and uses therefor |
| WO2004000873A2 (en) * | 2002-06-25 | 2003-12-31 | City Of Hope | Adjuvant-free peptide vaccine |
| CA2484941A1 (en) | 2002-07-24 | 2004-02-05 | Intercell Ag | Antigens encoded by alternative reading frame from pathogenic viruses |
| EP2402026A3 (en) | 2002-09-13 | 2012-04-18 | Intercell AG | Method for isolating hepatitis C virus peptides |
| US20040072262A1 (en) * | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
| ATE485056T1 (de) | 2003-03-24 | 2010-11-15 | Intercell Ag | Verbesserte impfstoffe |
| US7163685B2 (en) * | 2003-04-16 | 2007-01-16 | City Of Hope | Human cytomegalovirus antigens expressed in MVA and methods of use |
| US20050232933A1 (en) * | 2003-09-30 | 2005-10-20 | Zaia John A | CMV-IE1 peptides and method of use |
| JP2007511760A (ja) * | 2003-11-03 | 2007-05-10 | ベックマン コールター インコーポレーティッド | Mhc結合ペプチドを検出するための溶液ベースの方法 |
| US9090673B2 (en) * | 2003-12-12 | 2015-07-28 | City Of Hope | Synthetic conjugate of CpG DNA and T-help/CTL peptide |
| JP2007536522A (ja) * | 2004-05-07 | 2007-12-13 | ベックマン コールター インコーポレーティッド | Ctlの媒介による抗原提示細胞の溶解を検出するためのmhc架橋系 |
| US7678379B2 (en) * | 2004-06-17 | 2010-03-16 | Beckman Coulter, Inc. | Mycobacterium tuberculosis epitopes and methods of use thereof |
| WO2006101909A2 (en) * | 2005-03-16 | 2006-09-28 | Ischemix, Inc. | Combination therapy for treating or preventing diseases |
| US8518697B2 (en) * | 2006-04-04 | 2013-08-27 | Washington University | Single chain trimers and uses therefor |
| US7977457B2 (en) * | 2006-05-19 | 2011-07-12 | Teva Pharmaceutical Industries Ltd. | Fusion proteins, uses thereof and processes for producing same |
| US20080138354A1 (en) * | 2006-07-21 | 2008-06-12 | City Of Hope | Cytomegalovirus vaccine |
| EP2361930A3 (en) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases |
| EP3620465B1 (en) | 2007-07-03 | 2025-02-19 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| CA2728739C (en) | 2008-06-20 | 2017-07-11 | Duke University | Use of human cytomegalovirus antigens to enhance immune responses to cancer cells |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| WO2010037397A1 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cmv immune monitoring |
| WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| ES2912042T3 (es) | 2011-06-24 | 2022-05-24 | Nono Inc | Terapia de combinación para isquemia |
| US9241970B2 (en) * | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| EP3049092A4 (en) * | 2013-09-24 | 2017-09-06 | Duke University | Compositions, methods and kits for eliciting an immune response |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| EP3364981A4 (en) | 2015-10-22 | 2019-08-07 | ModernaTX, Inc. | VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| MA46584A (fr) | 2016-10-21 | 2019-08-28 | Modernatx Inc | Vaccin contre le cytomégalovirus humain |
| EP3706783A1 (en) * | 2017-11-06 | 2020-09-16 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Cancer treatment utilizing pre-existing microbial immunity |
| CN109748952B (zh) * | 2018-05-02 | 2020-09-15 | 中国药科大学 | 辅助性表位肽及其应用 |
| US12258373B2 (en) | 2018-12-17 | 2025-03-25 | Immudex Aps | Panel comprising Borrelia MHC multimers |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白B(gB)多肽 |
| US11406703B2 (en) | 2020-08-25 | 2022-08-09 | Modernatx, Inc. | Human cytomegalovirus vaccine |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4762780A (en) | 1984-04-17 | 1988-08-09 | The Regents Of The University Of California | Method and composition for screening and diagnosing "HCMV" |
| GB8404368D0 (en) | 1984-02-20 | 1984-03-28 | Cogent Ltd | Monoclonal antibodies to human cytomegalovirus |
| US5075213A (en) | 1984-07-27 | 1991-12-24 | City Of Hope | Method for detection and prevention of human cytomegalovirus infection |
| US6207161B1 (en) * | 1986-07-16 | 2001-03-27 | City Of Hope | Induction of cytolytic T-lymphocytes with cytomegalovirus polypeptides |
| WO1994000150A1 (en) | 1992-06-25 | 1994-01-06 | City Of Hope | Induction of cytolytic t-lymphocytes with cytomegalovirus polypeptides |
| AU651397B2 (en) | 1990-09-28 | 1994-07-21 | Fred Hutchinson Cancer Research Center | Method for producing TH-independent cytotoxic T lymphocytes |
| US5470730A (en) | 1990-09-28 | 1995-11-28 | Immunex | Method for producing TH -independent cytotoxic T lymphocytes |
| US5405940A (en) | 1992-08-31 | 1995-04-11 | Ludwig Institute For Cancer Research | Isolated nonapeptides derived from MAGE genes and uses thereof |
| AU698962B2 (en) | 1993-09-14 | 1998-11-12 | Epimmune, Inc. | Alteration of immune response using pan DR-binding peptides |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| US5635363A (en) | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
| US6448389B1 (en) | 1996-04-23 | 2002-09-10 | The Wistar Institute Of Anatomy And Biology | Human cytomegalovirus DNA constructs and uses therefor |
| US6156317A (en) | 1996-11-12 | 2000-12-05 | City Of Hope | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| US6074645A (en) | 1996-11-12 | 2000-06-13 | City Of Hope | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| FR2757169B1 (fr) | 1996-12-13 | 1999-03-05 | Inst Nat Sante Rech Med | Proteine de fusion comportant tout ou partie de la proteine pp65 de cmv humain, utile notamment dans la preparation d'un vaccin |
| ATE497971T1 (de) | 1999-06-04 | 2011-02-15 | Florian Kern | Peptide zur vakzinierung gegen das humane cmv |
-
2000
- 2000-10-20 US US09/692,170 patent/US6562345B1/en not_active Expired - Lifetime
-
2001
- 2001-03-16 EP EP20010922443 patent/EP1268529A2/en not_active Withdrawn
- 2001-03-16 JP JP2001571713A patent/JP5602332B2/ja not_active Expired - Lifetime
- 2001-03-16 AU AU2001249243A patent/AU2001249243B2/en not_active Expired
- 2001-03-16 CA CA 2401638 patent/CA2401638C/en not_active Expired - Lifetime
- 2001-03-16 AU AU4924301A patent/AU4924301A/xx active Pending
- 2001-03-16 WO PCT/US2001/008576 patent/WO2001072782A2/en not_active Ceased
- 2001-10-30 US US09/984,365 patent/US6733973B2/en not_active Expired - Lifetime
-
2002
- 2002-09-11 US US10/238,607 patent/US6727093B2/en not_active Expired - Lifetime
-
2003
- 2003-04-03 US US10/405,231 patent/US6726910B2/en not_active Expired - Lifetime
- 2003-10-31 US US10/697,055 patent/US6843992B2/en not_active Expired - Lifetime
- 2003-12-17 US US10/736,640 patent/US7160685B2/en not_active Expired - Fee Related
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