JP2003522133A - 持続性導入遺伝子発現を実現する方法 - Google Patents

持続性導入遺伝子発現を実現する方法

Info

Publication number
JP2003522133A
JP2003522133A JP2001548743A JP2001548743A JP2003522133A JP 2003522133 A JP2003522133 A JP 2003522133A JP 2001548743 A JP2001548743 A JP 2001548743A JP 2001548743 A JP2001548743 A JP 2001548743A JP 2003522133 A JP2003522133 A JP 2003522133A
Authority
JP
Japan
Prior art keywords
composition
inflammatory
administration
nucleic acid
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001548743A
Other languages
English (en)
Japanese (ja)
Inventor
パトリック リュ
デービット・レオナルド エンニスト
メルバット ミーナ
Original Assignee
ノバルティス アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2003522133A publication Critical patent/JP2003522133A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2001548743A 1999-12-28 2000-12-27 持続性導入遺伝子発現を実現する方法 Pending JP2003522133A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47301899A 1999-12-28 1999-12-28
US09/473,018 1999-12-28
PCT/EP2000/013297 WO2001048231A2 (en) 1999-12-28 2000-12-27 Method of achieving persistent transgene expression

Publications (1)

Publication Number Publication Date
JP2003522133A true JP2003522133A (ja) 2003-07-22

Family

ID=23877847

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001548743A Pending JP2003522133A (ja) 1999-12-28 2000-12-27 持続性導入遺伝子発現を実現する方法

Country Status (8)

Country Link
EP (1) EP1242608A2 (de)
JP (1) JP2003522133A (de)
CN (2) CN1310679C (de)
AU (1) AU3164801A (de)
CA (1) CA2395544A1 (de)
IL (1) IL150485A0 (de)
NZ (1) NZ531527A (de)
WO (1) WO2001048231A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007262064A (ja) * 2006-03-27 2007-10-11 China Medical Univ 乳児における慢性肺疾患のリスクの低減

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003223718B2 (en) * 2002-04-25 2007-08-16 The Scripps Research Institute Treatment and prevention of pulmonary conditions
CN101495498B (zh) * 2005-02-07 2013-09-18 基因信息公司 轻度骨关节炎生物标志物及其用途
CN113384705A (zh) * 2021-06-28 2021-09-14 西南大学 泊洛沙姆修饰的脂质体的制备及在口服药物递送中的应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04504125A (ja) * 1989-03-21 1992-07-23 バイカル・インコーポレイテッド 脊椎動物における外因性ポリヌクレオチド配列の発現
WO1996004932A1 (en) * 1994-08-09 1996-02-22 Cytrx Corporation Novel vaccine adjuvant and vaccine
WO1997015330A1 (en) * 1995-10-23 1997-05-01 Hyal Pharmaceutical Australia Limited Hyaluronic acid as dna carrier for gene therapy and vegf antisense dna to treat abnormal retinal vascularization
JPH10507758A (ja) * 1994-10-19 1998-07-28 ジェネティック セラピー，インコーポレイテッド アデノウイルスおよび免疫抑制剤同時反復投与を伴う遺伝子治療
JPH10509048A (ja) * 1994-11-18 1998-09-08 スプラテック ファーマ，インコーポレイテッド ポリヌクレオチド組成物
WO1999001579A1 (en) * 1997-07-01 1999-01-14 Isis Pharmaceuticals, Inc. Compositions and methods for the delivery of oligonucleotides via the alimentary canal

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693622A (en) * 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5633227A (en) * 1994-09-12 1997-05-27 Miles, Inc. Secretory leukocyte protease inhibitor as an inhibitor of tryptase
US6353055B1 (en) * 1994-11-18 2002-03-05 Supratek Pharma Inc. Polynucleotide compositions
WO1996015780A1 (en) * 1994-11-23 1996-05-30 Isis Pharmaceuticals, Inc. Compositions and methods for preventing and treating allograft rejection
DE19711800A1 (de) * 1997-03-21 1998-09-24 Hoechst Ag Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04504125A (ja) * 1989-03-21 1992-07-23 バイカル・インコーポレイテッド 脊椎動物における外因性ポリヌクレオチド配列の発現
WO1996004932A1 (en) * 1994-08-09 1996-02-22 Cytrx Corporation Novel vaccine adjuvant and vaccine
JPH10507758A (ja) * 1994-10-19 1998-07-28 ジェネティック セラピー，インコーポレイテッド アデノウイルスおよび免疫抑制剤同時反復投与を伴う遺伝子治療
JPH10509048A (ja) * 1994-11-18 1998-09-08 スプラテック ファーマ，インコーポレイテッド ポリヌクレオチド組成物
WO1997015330A1 (en) * 1995-10-23 1997-05-01 Hyal Pharmaceutical Australia Limited Hyaluronic acid as dna carrier for gene therapy and vegf antisense dna to treat abnormal retinal vascularization
WO1999001579A1 (en) * 1997-07-01 1999-01-14 Isis Pharmaceuticals, Inc. Compositions and methods for the delivery of oligonucleotides via the alimentary canal

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007262064A (ja) * 2006-03-27 2007-10-11 China Medical Univ 乳児における慢性肺疾患のリスクの低減

Also Published As

Publication number Publication date
CA2395544A1 (en) 2001-07-05
CN101011584A (zh) 2007-08-08
CN1310679C (zh) 2007-04-18
EP1242608A2 (de) 2002-09-25
NZ531527A (en) 2005-10-28
CN1433477A (zh) 2003-07-30
AU3164801A (en) 2001-07-09
WO2001048231A2 (en) 2001-07-05
IL150485A0 (en) 2002-12-01
WO2001048231A3 (en) 2002-04-04

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