JP2003521229A - 分泌及び膜貫通ポリペプチドとそれをコードする核酸 - Google Patents

分泌及び膜貫通ポリペプチドとそれをコードする核酸

Info

Publication number
JP2003521229A
JP2003521229A JP2000588351A JP2000588351A JP2003521229A JP 2003521229 A JP2003521229 A JP 2003521229A JP 2000588351 A JP2000588351 A JP 2000588351A JP 2000588351 A JP2000588351 A JP 2000588351A JP 2003521229 A JP2003521229 A JP 2003521229A
Authority
JP
Japan
Prior art keywords
seq
polypeptide
sequence identity
amino acid
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000588351A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003521229A5 (ko
Inventor
ポッツタイン，デーヴィッド
デスノイヤーズ，ラック
フェララ，ナポレオン
フォン，シャーマン
ガオ，ウェイ−キャン
ゴッダード，オードリー
ガーニー，オースティン，エル．
パン，ジェームズ
ロイ，マーガレット，アン
ティモシー エー． スチュワート
タマス，ダニエル
ワタナベ，コリン，ケー．
ウッド，ウィリアム，アイ．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2003521229A publication Critical patent/JP2003521229A/ja
Publication of JP2003521229A5 publication Critical patent/JP2003521229A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000588351A 1998-12-16 1999-12-01 分泌及び膜貫通ポリペプチドとそれをコードする核酸 Withdrawn JP2003521229A (ja)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US11314598P 1998-12-16 1998-12-16
US11285198P 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11556599P 1999-01-12 1999-01-12
US11555899P 1999-01-12 1999-01-12
US11573399P 1999-01-12 1999-01-12
US60/115,733 1999-01-12
US60/115,558 1999-01-12
US60/115,565 1999-01-12
US11934199P 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P 1999-02-12 1999-02-12
US60/119,965 1999-02-12
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
US99/12252 1999-06-02
PCT/US1999/028634 WO2000036102A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Child Applications (3)

Application Number Title Priority Date Filing Date
JP2003293651A Division JP2004041218A (ja) 1998-12-16 2003-08-14 分泌ポリペプチドとそれをコードする核酸
JP2003293650A Division JP2004041217A (ja) 1998-12-16 2003-08-14 分泌及び膜貫通ポリペプチドとそれをコードする核酸
JP2006282251A Division JP2007075118A (ja) 1998-12-16 2006-10-17 分泌及び膜貫通ポリペプチドとそれをコードする核酸

Publications (2)

Publication Number Publication Date
JP2003521229A true JP2003521229A (ja) 2003-07-15
JP2003521229A5 JP2003521229A5 (ko) 2005-12-22

Family

ID=27578476

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2000588351A Withdrawn JP2003521229A (ja) 1998-12-16 1999-12-01 分泌及び膜貫通ポリペプチドとそれをコードする核酸
JP2003293651A Withdrawn JP2004041218A (ja) 1998-12-16 2003-08-14 分泌ポリペプチドとそれをコードする核酸
JP2003293650A Withdrawn JP2004041217A (ja) 1998-12-16 2003-08-14 分泌及び膜貫通ポリペプチドとそれをコードする核酸
JP2006282251A Withdrawn JP2007075118A (ja) 1998-12-16 2006-10-17 分泌及び膜貫通ポリペプチドとそれをコードする核酸
JP2007156006A Withdrawn JP2007312779A (ja) 1998-12-16 2007-06-13 分泌及び膜貫通ポリペプチドとそれをコードする核酸

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2003293651A Withdrawn JP2004041218A (ja) 1998-12-16 2003-08-14 分泌ポリペプチドとそれをコードする核酸
JP2003293650A Withdrawn JP2004041217A (ja) 1998-12-16 2003-08-14 分泌及び膜貫通ポリペプチドとそれをコードする核酸
JP2006282251A Withdrawn JP2007075118A (ja) 1998-12-16 2006-10-17 分泌及び膜貫通ポリペプチドとそれをコードする核酸
JP2007156006A Withdrawn JP2007312779A (ja) 1998-12-16 2007-06-13 分泌及び膜貫通ポリペプチドとそれをコードする核酸

Country Status (8)

Country Link
EP (1) EP1141285A2 (ko)
JP (5) JP2003521229A (ko)
KR (2) KR100468977B1 (ko)
AU (7) AU777006B2 (ko)
CA (1) CA2348757A1 (ko)
IL (11) IL142794A0 (ko)
MX (1) MXPA01006057A (ko)
WO (1) WO2000036102A2 (ko)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US6914130B2 (en) * 1998-06-17 2005-07-05 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
AU2008201101B2 (en) * 1999-03-11 2011-01-20 Merck Serono Sa Vascular adhesion molecules and modulation of their function
CN1637019A (zh) 1999-03-11 2005-07-13 Rmf迪克塔吉恩有限公司 血管粘着分子及其功能的调节
KR100543857B1 (ko) * 1999-09-01 2006-01-23 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제
DE19947010A1 (de) * 1999-09-30 2001-04-05 Universitaetsklinikum Freiburg Das Gen PRV-1 und dessen Verwendung
WO2001083719A2 (en) * 2000-04-28 2001-11-08 Millennium Pharmaceuticals, Inc. 25692, a novel human o-methyltransferase family member and uses thereof
GB0110273D0 (en) * 2001-04-26 2001-06-20 Inpharmatica Ltd Novel proteins
NZ533736A (en) * 2001-12-19 2006-09-29 Genentech Inc Compositions and methods for the diagnosis and treatment of tumor and inhibiting cell growth
JPWO2003097862A1 (ja) * 2002-05-17 2005-09-15 協和醗酵工業株式会社 抗糖尿病作用を有する物質の探索方法
US20050283842A1 (en) * 2002-10-02 2005-12-22 Karsten Eulenberg Mipp1 homologous nucleic acids and proteins involved in the regulation of energy homeostatis
KR20150055628A (ko) 2005-11-04 2015-05-21 제넨테크, 인크. 안질환 치료를 위한 보체 경로 억제제의 용도
EP2068928A2 (en) 2006-09-28 2009-06-17 Merck Serono SA Junctional adhesion molecule-c (jam-c) binding compounds and methods of their use
PL2097455T3 (pl) 2006-11-02 2015-04-30 Genentech Inc Humanizowane przeciwciała przeciw czynnikowi D
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
SG190596A1 (en) 2008-05-06 2013-06-28 Genentech Inc Affinity matured crig variants
MX2016001854A (es) 2013-08-12 2016-09-06 Genentech Inc Composiciones y metodo para tratar condiciones asociadas con el complemento.
TW201623337A (zh) 2014-05-01 2016-07-01 建南德克公司 抗－因子ｄ抗體變異體及其用途
JP2018536650A (ja) 2015-10-30 2018-12-13 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体変異体コンジュゲート及びその使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014331A1 (en) * 1994-11-07 1996-05-17 Merck & Co., Inc. Modified neuropeptide y receptors
AU1532697A (en) * 1996-01-12 1997-08-01 Genetics Institute Inc. Beta-chemokine, h1305 (mcp-2)
JP3646191B2 (ja) * 1996-03-19 2005-05-11 大塚製薬株式会社 ヒト遺伝子
JP2001515361A (ja) * 1997-05-06 2001-09-18 ザイモジェネティクス，インコーポレイティド 新規な腫瘍抗原
DE19818620A1 (de) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Blase-Normal
EP1090118A2 (en) * 1998-06-26 2001-04-11 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
WO2000004135A2 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human scad-related molecules, scrm-1 and scrm-2
DE19849044A1 (de) * 1998-10-23 2000-04-27 Univ Ludwigs Albert Das Gen PRV-1 und dessen Verwendung
EP1131428A2 (en) * 1998-11-19 2001-09-12 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins
DK1607402T3 (da) * 1999-03-08 2007-04-16 Genentech Inc Sammensætninger og fremgangsmåder til tumorbehandling

Also Published As

Publication number Publication date
KR20010101224A (ko) 2001-11-14
IL142794A (en) 2008-03-20
JP2007312779A (ja) 2007-12-06
EP1141285A2 (en) 2001-10-10
KR100468978B1 (ko) 2005-02-02
IL200883A0 (en) 2010-05-17
AU2004237921A1 (en) 2005-01-13
AU2004237920A1 (en) 2005-01-13
AU2004237922A1 (en) 2005-01-13
AU2004237842A1 (en) 2005-01-13
IL188580A0 (en) 2008-04-13
WO2000036102A2 (en) 2000-06-22
AU2004237922B2 (en) 2007-09-06
AU2004237842B2 (en) 2007-09-20
AU2004237919A1 (en) 2005-01-13
IL142794A0 (en) 2002-03-10
AU1932000A (en) 2000-07-03
KR100468977B1 (ko) 2005-02-02
IL201001A0 (en) 2010-05-17
AU2004237923A1 (en) 2005-01-13
WO2000036102A3 (en) 2000-11-09
AU2004237921B2 (en) 2007-08-23
KR20040096629A (ko) 2004-11-16
AU2004237920B2 (en) 2007-08-23
IL188581A0 (en) 2008-04-13
JP2004041218A (ja) 2004-02-12
IL188579A0 (en) 2008-04-13
AU2004237923B2 (en) 2007-09-06
AU777006B2 (en) 2004-09-30
JP2004041217A (ja) 2004-02-12
MXPA01006057A (es) 2003-09-10
IL188577A0 (en) 2008-04-13
AU2004237919B2 (en) 2007-09-06
IL188578A0 (en) 2008-04-13
IL201030A0 (en) 2010-05-17
CA2348757A1 (en) 2000-06-22
IL188576A0 (en) 2008-04-13
JP2007075118A (ja) 2007-03-29

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