JP2003519164A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003519164A5 JP2003519164A5 JP2001549618A JP2001549618A JP2003519164A5 JP 2003519164 A5 JP2003519164 A5 JP 2003519164A5 JP 2001549618 A JP2001549618 A JP 2001549618A JP 2001549618 A JP2001549618 A JP 2001549618A JP 2003519164 A5 JP2003519164 A5 JP 2003519164A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- release
- polymer
- formulation
- dth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17413799P | 1999-12-31 | 1999-12-31 | |
US60/174,137 | 1999-12-31 | ||
PCT/US2001/000030 WO2001049249A2 (fr) | 1999-12-31 | 2001-01-02 | Formulation pharmaceutique destinee a reguler la liberation dans le temps de composes biologiquement actifs a base d'une matrice polymere |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2003519164A JP2003519164A (ja) | 2003-06-17 |
JP2003519164A5 true JP2003519164A5 (fr) | 2011-04-28 |
Family
ID=22634986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001549618A Pending JP2003519164A (ja) | 1999-12-31 | 2001-01-02 | ポリマーマトリクスに基づく生理活性化合物徐放調節用医薬製剤 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1263453A4 (fr) |
JP (1) | JP2003519164A (fr) |
AU (1) | AU784226B2 (fr) |
CA (1) | CA2396037A1 (fr) |
WO (1) | WO2001049249A2 (fr) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1251864A4 (fr) * | 1999-12-31 | 2006-02-22 | Univ Rutgers | Formulation pharmaceutique composee d'un melange polymere et d'un compose actif pour une liberation regulee dans le temps |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
ES2383525T3 (es) | 2003-11-05 | 2012-06-21 | Sarcode Bioscience Inc. | Moduladores de la adhesión celular |
CA2609053C (fr) | 2005-05-17 | 2017-04-25 | Sarcode Corporation | Compositions et procedes pour le traitement des troubles oculaires |
US8315700B2 (en) | 2006-02-08 | 2012-11-20 | Tyrx, Inc. | Preventing biofilm formation on implantable medical devices |
EP2114298B1 (fr) | 2006-02-08 | 2022-10-19 | Medtronic, Inc. | Prothèses de type treillis temporairement raidies |
US9265865B2 (en) | 2006-06-30 | 2016-02-23 | Boston Scientific Scimed, Inc. | Stent having time-release indicator |
JP2010508915A (ja) | 2006-11-06 | 2010-03-25 | タイレックス・ファーマ・インコーポレイテッド | 埋込型医療機器のためのメッシュパウチ |
US9023114B2 (en) | 2006-11-06 | 2015-05-05 | Tyrx, Inc. | Resorbable pouches for implantable medical devices |
CA2682190C (fr) | 2007-03-29 | 2015-01-27 | Tyrx Pharma, Inc. | Enveloppes polymeres biodegradables pour implants mammaires |
WO2008137807A1 (fr) | 2007-05-02 | 2008-11-13 | Tyrx Pharma, Inc. | Polymères de dihydroxybenzoate et leurs utilisations |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
ES2393885T7 (es) | 2007-06-04 | 2014-01-30 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
EP3797775A1 (fr) | 2007-10-19 | 2021-03-31 | Novartis AG | Compositions et procédés pour le traitement de la rétinopathie diabétique |
WO2009139817A2 (fr) | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Produit pharmaceutique cristallin et ses procédés de préparation et d'utilisation |
ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
US8652525B2 (en) | 2008-07-10 | 2014-02-18 | Tyrx, Inc. | NSAID delivery from polyarylates |
AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
JP5671463B2 (ja) | 2008-09-22 | 2015-02-18 | タイレックス・インコーポレイテッドTyrx Inc. | アミノフェノールエステルからの直鎖ポリエステルアミド |
US9839628B2 (en) | 2009-06-01 | 2017-12-12 | Tyrx, Inc. | Compositions and methods for preventing sternal wound infections |
EP2437724B1 (fr) * | 2009-06-01 | 2015-09-30 | Tyrx, Inc. | Compositions et méthodes pour prévenir les infections de blessures sternales |
US9080015B2 (en) * | 2009-07-31 | 2015-07-14 | Rutgers, The State University Of New Jersey | Biocompatible polymers for medical devices |
US8409279B2 (en) | 2009-10-01 | 2013-04-02 | Lipose Corporation | Breast implant implantation method and apparatus |
US8378105B2 (en) | 2009-10-21 | 2013-02-19 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
AU2011293344B2 (en) | 2010-08-25 | 2015-07-30 | Medtronic, Inc. | Novel medical device coatings |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
WO2012064963A1 (fr) | 2010-11-12 | 2012-05-18 | Tyrx, Inc. | Dispositifs d'ancrage comprenant un principe pharmaceutique actif |
US9381281B2 (en) | 2011-07-20 | 2016-07-05 | Tyrx, Inc. | Drug eluting mesh to prevent infection of indwelling transdermal devices |
MX2015001098A (es) | 2012-07-25 | 2015-09-25 | Sarcode Bioscience Inc | Inhibidor del antigeno-1 asociado a la funcion del linfocito (lfa-1) y polimorfo del mismo. |
AU2014218599C1 (en) | 2013-02-25 | 2018-09-06 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for use in colonic cleansing |
WO2014137454A1 (fr) | 2013-03-07 | 2014-09-12 | Tyrx, Inc. | Procédés et compositions permettant d'inhiber l'assemblage de cellules microbiennes se liant de façon irréversible à la surface de dispositifs médicaux |
CA2905435A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions utiles pour le traitement de troubles gastro-intestinaux |
JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
EP3054969B1 (fr) | 2013-10-10 | 2021-03-10 | Bausch Health Ireland Limited | Agonistes de guanylate cyclase utiles pour le traitement de troubles induits par les opioïdes |
WO2015069305A1 (fr) | 2013-11-08 | 2015-05-14 | Tyrx, Inc. | Compositions antimicrobiennes et procédés de prévention d'infection dans des sites d'incision chirurgicale |
WO2016020308A1 (fr) * | 2014-08-04 | 2016-02-11 | Janssen Sciences Ireland Uc | Forme posologique solide comprimée |
CA3009814A1 (fr) | 2016-01-11 | 2017-07-20 | Synergy Pharmaceuticals, Inc. | Formulations et methodes pour traiter la rectocolite hemorragique |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5587507A (en) * | 1995-03-31 | 1996-12-24 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
US5658995A (en) * | 1995-11-27 | 1997-08-19 | Rutgers, The State University | Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide) |
US6120491A (en) * | 1997-11-07 | 2000-09-19 | The State University Rutgers | Biodegradable, anionic polymers derived from the amino acid L-tyrosine |
WO1998036013A1 (fr) * | 1997-02-18 | 1998-08-20 | Rutgers, The State University | Monomeres derives d'acides hydroxyliques et polymeres prepares a partir de ceux-ci |
DE19719817A1 (de) * | 1997-05-13 | 1998-11-19 | Hoechst Ag | Substituierte 6- und 7-Aminotetrahydroisochinolincarbonsäuren |
ZA9811377B (en) * | 1997-12-12 | 1999-08-27 | Expression Genetics Inc | Positively charged poly[alpha-(omega-aminoalkyl) glycolic acid[ for the delivery of a bioactive agent via tissue and cellular uptake. |
JP4312384B2 (ja) * | 1998-04-13 | 2009-08-12 | ラットガーズ ザ ステイト ユニヴァーシティ | コポリマーライブラリーの構築 |
AU2373200A (en) * | 1999-02-05 | 2000-08-25 | Alien Technology Corporation | Apparatuses and methods for forming assemblies |
-
2001
- 2001-01-02 CA CA002396037A patent/CA2396037A1/fr not_active Abandoned
- 2001-01-02 WO PCT/US2001/000030 patent/WO2001049249A2/fr active Application Filing
- 2001-01-02 AU AU29255/01A patent/AU784226B2/en not_active Expired
- 2001-01-02 JP JP2001549618A patent/JP2003519164A/ja active Pending
- 2001-01-02 EP EP01939971A patent/EP1263453A4/fr not_active Ceased
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2003519164A5 (fr) | ||
Bose et al. | Biodegradable polymers for modern vaccine development | |
US4942035A (en) | Continuous release formulations | |
TWI250028B (en) | Biodegradable ph/thermosensitive hydrogel for sustained delivery of biologically active agents | |
Gombotz et al. | Protein release from alginate matrices | |
ES2432556T3 (es) | Métodos para fabricar dispositivos de suministro y sus dispositivos | |
US5529777A (en) | Hydrogel microencapsulated vaccines | |
US4863735A (en) | Biodegradable polymeric drug delivery system with adjuvant activity | |
US4882168A (en) | Polyesters containing alkylene oxide blocks as drug delivery systems | |
Kissel et al. | Parenteral protein delivery systems using biodegradable polyesters of ABA block structure, containing hydrophobic poly (lactide-co-glycolide) A blocks and hydrophilic poly (ethylene oxide) B blocks | |
CA1288344C (fr) | Systeme de dispensation de medicament | |
JP2007308500A (ja) | Gm−csfの放出の延長 | |
CA2203857A1 (fr) | Microparticules pour l'expression d'acide nucleique | |
WO2002036169A3 (fr) | Methodes et compositions pour ameliorer l'administration de molecules bioactives | |
PT863933E (pt) | Novos hidrogeis a base de copolimeros de bloco com res sequencias sua preparacao e sua aplicacao | |
NZ204643A (en) | Controlled release device containing polymer and acid anhydride | |
KR20090086478A (ko) | 약물 전달을 위한 생분해가능 블록 공중합성 조성물 | |
EP0258780A2 (fr) | Polyesters contenant des séquences d'oxyde d'alkylène et leur utilisation comme systèmes de libération de médicaments | |
CN101331173A (zh) | 生物相容性嵌段共聚物、其用途和制造方法 | |
CA2424936A1 (fr) | Composition de vaccin renfermant une substance immunologiquement active logee dans des microparticules faites d'un amidon au poids moleculaire reduit | |
CA2167081A1 (fr) | Vaccins microencapsules a base d'hydrogel | |
WO1995002416A9 (fr) | Vaccins microencapsules sur une base d'hydrogel | |
Ghahremankhani et al. | PLGA-PEG-PLGA tri-block copolymers as an in-situ gel forming system for calcitonin delivery | |
AL et al. | Biodegradable polymers: Which, when and why? | |
JP2013536177A (ja) | 2−ヒドロキシアルキル酸から調製されたポリマーを含む組成物 |