|
US20050085555A1
(en)
*
|
1997-08-21 |
2005-04-21 |
Murphy Michael A. |
Composition, synthesis and therapeutic applications of polyamines
|
|
US20030013772A1
(en)
*
|
2000-02-23 |
2003-01-16 |
Murphy Michael A. |
Composition, synthesis and therapeutic applications of polyamines
|
|
BR0010700A
(pt)
|
1999-04-30 |
2002-02-13 |
Slil Biomedical Corp |
Conjugados análogos de poliamina e conjugados de quinona como terapias para cânceres e doenças na próstata
|
|
HK1040993B
(en)
*
|
1999-04-30 |
2006-11-10 |
Cellgate, Inc. |
Polyamines and their use in therapy
|
|
EP1337504A4
(en)
|
2000-11-08 |
2005-10-05 |
Cellgate Inc |
NOVEL AMINO ACID CONJUGATES AND POLYAMINE ANALOGUES USEFUL AS ANTICANCING AGENTS
|
|
AU2002340224B2
(en)
*
|
2001-10-16 |
2008-11-27 |
Progen Pharmaceuticals, Inc |
Oligoamine compounds and derivatives thereof for cancer therapy
|
|
JP2004189714A
(ja)
*
|
2002-12-09 |
2004-07-08 |
Rasanen Tiina-Liisa |
すい臓炎の治療と予防ならびに肝臓再生機能の誘導のための薬剤
|
|
JP4860700B2
(ja)
|
2005-09-20 |
2012-01-25 |
シェーリング コーポレイション |
ヒスタミンＨ３アンタゴニストとして有用な、１−［［１−［（２−アミノ−６−メチル−４−ピリジニル）メチル］−４−フルオロ−４−ピペリジニル］カルボニル］−４−［２−（２−ピリジニル）−３Ｈ−イミダゾ［４，５−ｂ］ピリジン−３−イル］ピペリジン
|
|
WO2008151257A2
(en)
|
2007-06-04 |
2008-12-11 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
US8034782B2
(en)
|
2008-07-16 |
2011-10-11 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
US8153611B2
(en)
*
|
2007-06-28 |
2012-04-10 |
Basf Beauty Care Solutions France S.A.S. |
Use of sulfated oligosaccharides as slimming cosmetic ingredients
|
|
BRPI0813420B1
(pt)
*
|
2007-06-28 |
2018-05-15 |
Basf Beauty Care Solutions France Sas |
Uso de uma preparação, composição, e, método cosmético de cuidado para emagrecimento
|
|
FR2917971B1
(fr)
|
2007-06-28 |
2009-10-23 |
Engelhard Lyon Soc Par Actions |
Composition amincissante
|
|
CA2703203C
(en)
|
2007-10-22 |
2015-12-15 |
Schering Corporation |
Bicyclic heterocycle derivatives and methods of use thereof
|
|
EP2297117B1
(en)
|
2008-05-19 |
2012-10-31 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycle derivatives and use thereof as gpr119 modulators
|
|
EP2810951B1
(en)
|
2008-06-04 |
2017-03-15 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
RU2392933C2
(ru)
*
|
2008-07-18 |
2010-06-27 |
Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) |
Средство, обладающее гиполипидемическими свойствами
|
|
EP2318388A2
(en)
|
2008-07-23 |
2011-05-11 |
Schering Corporation |
Tricyclic spirocycle derivatives and methods of use thereof
|
|
AR073412A1
(es)
|
2008-10-03 |
2010-11-03 |
Schering Corp |
Derivados de espiro imidazolona como antagonistas del receptor glucagon y composiciones que los comprende.
|
|
CA2739491A1
(en)
|
2008-10-16 |
2010-04-22 |
Schering Corporation |
Azine derivatives and methods of use thereof
|
|
WO2010075069A1
(en)
|
2008-12-16 |
2010-07-01 |
Schering Corporation |
Bicyclic pyranone derivatives as nicotinic acid receptor agonists
|
|
US20110245209A1
(en)
|
2008-12-16 |
2011-10-06 |
Schering Corporation |
Pyridopyrimidine derivatives and methods of use thereof
|
|
US8283360B2
(en)
|
2008-12-19 |
2012-10-09 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocyclic derivatives and methods of use thereof
|
|
EP2379565A1
(en)
|
2008-12-19 |
2011-10-26 |
Schering Corporation |
Piperidine and piperazine derivatives and methods of use thereof
|
|
US8410122B2
(en)
|
2008-12-23 |
2013-04-02 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycle derivatives and methods of use thereof
|
|
WO2010075273A1
(en)
|
2008-12-23 |
2010-07-01 |
Schering Corporation |
Bicyclic heterocycle derivatives and methods of use thereof
|
|
JP2012513469A
(ja)
|
2008-12-23 |
2012-06-14 |
シェーリング コーポレイション |
ピリミジン誘導体及びその使用法
|
|
JP2012520886A
(ja)
|
2009-03-18 |
2012-09-10 |
シェーリング コーポレイション |
ジアシルグリセロールアシルトランスフェラーゼの阻害剤としての二環式化合物
|
|
EP2414348B1
(en)
|
2009-04-03 |
2013-11-20 |
Merck Sharp & Dohme Corp. |
Bicyclic piperidine and piperazine derivatives as gpcr modulators for the treatment of obesity, diabetes and other metabolic disorders
|
|
AR076024A1
(es)
|
2009-04-03 |
2011-05-11 |
Schering Corp |
Derivados de heterociclos biciclicos puenteados y metodos de uso de los mismos
|
|
US8470773B2
(en)
|
2009-06-12 |
2013-06-25 |
Merck Sharp & Dohme Corp. |
Thiophenes as glucagon receptor antagonists, compositions, and methods for their use
|
|
WO2011031628A1
(en)
|
2009-09-14 |
2011-03-17 |
Schering Corporation |
Inhibitors of diacylglycerol acyltransferase
|
|
US8759357B2
(en)
|
2009-10-08 |
2014-06-24 |
Merck Sharp & Dohme Corp. |
Inhibitors of fatty acid binding protein (FABP)
|
|
AU2010313469A1
(en)
|
2009-10-29 |
2012-06-07 |
Merck Sharp & Dohme Corp. |
Bridged Bicyclic Piperidine Derivatives and methods of use thereof
|
|
WO2011062889A1
(en)
|
2009-11-23 |
2011-05-26 |
Schering Corporation |
Pyrimidine ether derivatives and methods of use thereof
|
|
EP2504010A4
(en)
|
2009-11-23 |
2013-04-17 |
Merck Sharp & Dohme |
Fused Bicyclic Pyrimidine Derivatives and Methods of Use Therefor
|
|
EP2503887B1
(en)
|
2009-11-24 |
2016-01-06 |
Merck Sharp & Dohme Corp. |
Substituted biaryl derivatives and methods of use thereof
|
|
US9173886B2
(en)
*
|
2010-03-12 |
2015-11-03 |
Trana Discovery, Inc. |
Antiviral compounds and methods of use thereof
|
|
WO2012027331A1
(en)
|
2010-08-27 |
2012-03-01 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
|
ITMI20130555A1
(it)
*
|
2013-04-09 |
2014-10-10 |
Giuliani Spa |
Composizione farmaceutica o cosmetica per contrastare l¿invecchiamento della pelle attraverso un¿azione antiinfiammatoria
|
|
CN105764916B
(zh)
|
2013-06-05 |
2021-05-18 |
博士医疗爱尔兰有限公司 |
鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
|