JP2003515331A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003515331A5 JP2003515331A5 JP2001541066A JP2001541066A JP2003515331A5 JP 2003515331 A5 JP2003515331 A5 JP 2003515331A5 JP 2001541066 A JP2001541066 A JP 2001541066A JP 2001541066 A JP2001541066 A JP 2001541066A JP 2003515331 A5 JP2003515331 A5 JP 2003515331A5
- Authority
- JP
- Japan
- Prior art keywords
- repertoire
- polypeptide
- naive
- polypeptides
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004196 processed proteins & peptides Human genes 0.000 description 58
- 108090000765 processed proteins & peptides Proteins 0.000 description 58
- 229920001184 polypeptide Polymers 0.000 description 57
- 239000003446 ligand Substances 0.000 description 27
- 238000000034 method Methods 0.000 description 24
- 108060003951 Immunoglobulin Proteins 0.000 description 3
- 102000018358 immunoglobulin Human genes 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 108091008874 T cell receptors Proteins 0.000 description 2
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000035772 mutation Effects 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 101000686985 Mouse mammary tumor virus (strain C3H) Protein PR73 Proteins 0.000 description 1
- 101150117115 V gene Proteins 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 210000004602 germ cell Anatomy 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 230000002621 immunoprecipitating effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 231100000617 superantigen Toxicity 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9928789.8 | 1999-12-03 | ||
| GBGB9928789.8A GB9928789D0 (en) | 1999-12-03 | 1999-12-03 | Naive screening method |
| PCT/GB2000/004629 WO2001040312A2 (en) | 1999-12-03 | 2000-12-04 | Naive screening method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003515331A JP2003515331A (ja) | 2003-05-07 |
| JP2003515331A5 true JP2003515331A5 (OSRAM) | 2008-01-10 |
Family
ID=10865786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001541066A Withdrawn JP2003515331A (ja) | 1999-12-03 | 2000-12-04 | ナイーブスクリーニング法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1234179A2 (OSRAM) |
| JP (1) | JP2003515331A (OSRAM) |
| AU (1) | AU1718701A (OSRAM) |
| CA (1) | CA2392939A1 (OSRAM) |
| GB (1) | GB9928789D0 (OSRAM) |
| WO (1) | WO2001040312A2 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115068A1 (en) * | 2000-06-23 | 2002-08-22 | Ian Tomlinson | Matrix screening method |
| US6815078B2 (en) | 2002-03-06 | 2004-11-09 | Eastman Kodak Company | Substrate for protein microarray containing functionalized polymer |
| US7153896B2 (en) | 2003-11-14 | 2006-12-26 | Eastman Kodak Company | Element for protein microarrays |
| US7235641B2 (en) | 2003-12-22 | 2007-06-26 | Micromet Ag | Bispecific antibodies |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| ES2155822T3 (es) * | 1990-12-06 | 2001-06-01 | Affymetrix Inc | Compuestos y su utilizacion en una estrategia de sintesis binaria. |
| GB9722131D0 (en) * | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2319828A1 (en) * | 1998-01-29 | 1999-08-05 | Miller, Samuel | High density arrays for proteome analysis and methods and compositions therefor |
| CA2318175A1 (en) * | 1998-02-04 | 1999-08-12 | Invitrogen Corporation | Microarrays and uses therefor |
-
1999
- 1999-12-03 GB GBGB9928789.8A patent/GB9928789D0/en not_active Ceased
-
2000
- 2000-12-04 WO PCT/GB2000/004629 patent/WO2001040312A2/en not_active Ceased
- 2000-12-04 CA CA002392939A patent/CA2392939A1/en not_active Abandoned
- 2000-12-04 JP JP2001541066A patent/JP2003515331A/ja not_active Withdrawn
- 2000-12-04 AU AU17187/01A patent/AU1718701A/en not_active Abandoned
- 2000-12-04 EP EP00979803A patent/EP1234179A2/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6680210B2 (en) | Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules | |
| CA2308791A1 (en) | Method to screen phage display libraries with different ligands | |
| Poetz et al. | Protein microarrays for antibody profiling: specificity and affinity determination on a chip | |
| US20040053340A1 (en) | Protein arrays | |
| Fodey et al. | Developments in the production of biological and synthetic binders for immunoassay and sensor-based detection of small molecules | |
| US20060003381A1 (en) | Methods for assembling protein microarrays | |
| Breitling et al. | High-density peptide arrays | |
| AU1541701A (en) | Direct screening method | |
| US20020137053A1 (en) | Collections of binding proteins and tags and uses thereof for nested sorting and high throughput screening | |
| JP2007513326A5 (OSRAM) | ||
| US20020115068A1 (en) | Matrix screening method | |
| EP1999474A1 (en) | Method for the detection and/or enrichment of analyte proteins and/or analyte peptides from a complex protein mixture | |
| JP2009531679A5 (ja) | 複合タンパク質混合物中の被分析タンパク質および／または被分析ペプチドを検出および／または濃縮するための方法 | |
| EP3224360A1 (en) | Method | |
| JP2004500013A5 (OSRAM) | ||
| US8318440B2 (en) | Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies | |
| US20110071046A1 (en) | Matrix screening method | |
| JP2005507648A5 (OSRAM) | ||
| Konthur et al. | High-throughput applications of phage display in proteomic analyses | |
| EP1292710B1 (en) | Matrix screening method | |
| WO2003062444A3 (en) | Array systems and methods | |
| Taussig et al. | Progress in antibody arrays | |
| Balass et al. | Recovery of high-affinity phage from a nitrostreptavidin matrix in phage-display technology | |
| Messmer et al. | Sequential determination of ligands binding to discrete components in heterogeneous mixtures by iterative panning and blocking (IPAB) | |
| Schultz et al. | The combinatorial library: a multifunctional resource |