JP2003514024A5 - - Google Patents

Download PDF

Info

Publication number
JP2003514024A5
JP2003514024A5 JP2001537962A JP2001537962A JP2003514024A5 JP 2003514024 A5 JP2003514024 A5 JP 2003514024A5 JP 2001537962 A JP2001537962 A JP 2001537962A JP 2001537962 A JP2001537962 A JP 2001537962A JP 2003514024 A5 JP2003514024 A5 JP 2003514024A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001537962A
Other languages
Japanese (ja)
Other versions
JP2003514024A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2000/001329 external-priority patent/WO2001035970A1/en
Publication of JP2003514024A publication Critical patent/JP2003514024A/ja
Publication of JP2003514024A5 publication Critical patent/JP2003514024A5/ja
Pending legal-status Critical Current

Links

JP2001537962A 1999-11-12 2000-11-08 細胞増殖性疾患の治療のためのウイルス Pending JP2003514024A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16487899P 1999-11-12 1999-11-12
US60/164,878 1999-11-12
PCT/CA2000/001329 WO2001035970A1 (en) 1999-11-12 2000-11-08 Viruses for the treatment of cellular proliferative disorders

Publications (2)

Publication Number Publication Date
JP2003514024A JP2003514024A (ja) 2003-04-15
JP2003514024A5 true JP2003514024A5 (US06573293-20030603-C00009.png) 2005-12-22

Family

ID=22596481

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001537962A Pending JP2003514024A (ja) 1999-11-12 2000-11-08 細胞増殖性疾患の治療のためのウイルス

Country Status (11)

Country Link
US (9) US6596268B1 (US06573293-20030603-C00009.png)
EP (2) EP1227828A1 (US06573293-20030603-C00009.png)
JP (1) JP2003514024A (US06573293-20030603-C00009.png)
AU (1) AU782020B2 (US06573293-20030603-C00009.png)
BR (1) BR0015491A (US06573293-20030603-C00009.png)
CA (2) CA2720361A1 (US06573293-20030603-C00009.png)
HK (1) HK1047698A1 (US06573293-20030603-C00009.png)
MX (1) MXPA02004736A (US06573293-20030603-C00009.png)
NZ (1) NZ518454A (US06573293-20030603-C00009.png)
WO (1) WO2001035970A1 (US06573293-20030603-C00009.png)
ZA (1) ZA200203041B (US06573293-20030603-C00009.png)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030044384A1 (en) * 1997-10-09 2003-03-06 Pro-Virus, Inc. Treatment of neoplasms with viruses
EP1227828A1 (en) 1999-11-12 2002-08-07 Oncolytics Biotech, Inc. Viruses for the treatment of cellular proliferative disorders
AUPQ425699A0 (en) 1999-11-25 1999-12-23 University Of Newcastle Research Associates Limited, The A method of treating a malignancy in a subject and a pharmaceutical composition for use in same
EP1244469A2 (en) * 1999-12-08 2002-10-02 Onyx Pharmaceuticals, Inc. Mutant simplex virus for treating unwanted hyperproliferative cell growth
US8491884B2 (en) 2000-05-03 2013-07-23 Oncolytics Biotech Inc. Virus clearance of neoplastic cells from mixed cellular compositions
AR028039A1 (es) 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas
AR028040A1 (es) * 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de virus de celulas neoplasticas a partir de composiciones celulares mixtas
US7306902B2 (en) 2002-06-28 2007-12-11 Oncolyties Biotech Inc. Oncolytic viruses as phenotyping agents for neoplasms
US20050013803A1 (en) * 2000-07-07 2005-01-20 Benjamin Thomas L. Diagnosing and treating cancer cells using mutant viruses
US20020147996A1 (en) * 2000-07-07 2002-10-10 Benjamin Thomas L. Diagnosing and treating cancer cells using Sal2
US20020156039A1 (en) * 2000-07-07 2002-10-24 Benjamin Thomas L. Diagnosing and treating cancer cells using Sal2
US20030157481A1 (en) * 2001-12-10 2003-08-21 Benjamin Thomas L. Diagnosing and treating cancer cells using T-HR mutants and their targets
AR035227A1 (es) * 2001-02-20 2004-05-05 Oncolytics Biotech Inc Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus
WO2003050135A2 (en) * 2001-12-07 2003-06-19 Board Of Regents The University Of Texas System Use a parapox b2l protein to modify immune responses to administered antigens
JP2005526099A (ja) * 2002-03-26 2005-09-02 オンコリティクス バイオテック, インコーポレイティッド 癌治療のための、va遺伝子が変異したアデノウイルスの使用
CA2483551A1 (en) * 2002-04-26 2003-11-06 Wellstat Biologics Corporation Immunogenic agent therapy using plasmapheresis or exchange transfusion
US20040180438A1 (en) * 2002-04-26 2004-09-16 Pachuk Catherine J. Methods and compositions for silencing genes without inducing toxicity
WO2004009763A2 (en) 2002-07-24 2004-01-29 Arizona Board Of Regents Use of vaccinia virus deleted for the e3l gene as a vaccine vector
EP1578396A4 (en) 2002-08-12 2007-01-17 David Kirn METHODS AND COMPOSITIONS RELATING TO POXVIRUS AND CANCER
AU2002953436A0 (en) 2002-12-18 2003-01-09 The University Of Newcastle Research Associates Limited A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis
BRPI0411526A (pt) 2003-06-18 2006-08-01 Genelux Corp vìrus de vaccinia e outros microrganismos recombinates modificados e usos dos mesmos
EP1648233A4 (en) * 2003-07-08 2006-08-23 Univ Arizona VACCINE VACCINE MUTANTS INSTEAD OF ONCOLYTIC AGENTS
US7442372B2 (en) 2003-08-29 2008-10-28 Biomarin Pharmaceutical Inc. Delivery of therapeutic compounds to the brain and other tissues
US7429481B2 (en) * 2004-09-14 2008-09-30 University Of Pittsburgh Targeting viruses using a modified sindbis glycoprotein
WO2006071966A2 (en) * 2004-12-29 2006-07-06 The Brigham And Women's Hospital, Inc. Rapamycin compounds in the treatment of neurofibromatosis type 1
BRPI0608310A2 (pt) * 2005-02-23 2009-12-08 Bavarian Nordic As uso de um poxvìrus modificado para a indução rápida de imunidade contra um poxvìrus ou outros agentes infecciosos
CN101137748B (zh) * 2005-03-07 2011-12-14 罗巴斯研究机构 粘液瘤病毒与雷帕霉素的组合在治疗性处理中的应用
US20070004767A1 (en) * 2005-06-30 2007-01-04 Gutmann David H Methods for treating neurofibromatosis 1
CA2617600A1 (en) 2005-08-01 2007-09-07 University Technologies International, Inc. Attenuated reovirus
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
US8980246B2 (en) 2005-09-07 2015-03-17 Sillajen Biotherapeutics, Inc. Oncolytic vaccinia virus cancer therapy
KR101772375B1 (ko) 2005-09-07 2017-08-29 신라젠(주) Gm-csf를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법
US20070190032A1 (en) * 2006-02-13 2007-08-16 Oncolytics Biotech Inc. Use of Local Immune Suppression to Enhance Oncolytic Viral Therapy
WO2008100292A2 (en) 2006-10-16 2008-08-21 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
WO2008156655A2 (en) 2007-06-15 2008-12-24 Genelux Corporation Vaccinia virus vectors encoding a sodium-dependent transporter protein for imaging and/or treatment of tumors
CA2693623A1 (en) * 2007-07-18 2009-01-22 Genelux Corporation Use of a chemotherapeutic agent in the preparation of a medicament for treating or ameliorating an adverse side effect associated with oncolytic viral therapy
WO2009135614A2 (en) * 2008-05-09 2009-11-12 Bayer Schering Pharma Aktiengesellschaft Use of a virus regimen for the treatment of diseases
WO2009139921A2 (en) * 2008-05-16 2009-11-19 Genelux Corporation Microorganisms for preventing and treating neoplasms accompanying cellular therapy
US20110086005A1 (en) * 2008-05-27 2011-04-14 Oncolytics Biotech Inc. Modulating interstitial pressure and oncolytic viral delivery and distribution
CA2937492C (en) 2008-11-11 2019-08-13 The Board Of Regents Of The University Of Texas System Inhibition of mammalian target of rapamycin
ES2848650T3 (es) 2009-09-14 2021-08-11 Sillajen Biotherapeutics Inc Terapia combinada contra el cáncer con virus vaccinia oncolítico
US9283211B1 (en) 2009-11-11 2016-03-15 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
BR112013017096A2 (pt) 2011-01-04 2020-09-01 Jennerex Inc. composição e métodos de indução de resposta citotóxica dependente de complemento mediado por anticorpo específico de tumor em animal tendo tumor, de geração de anticorpos in vivo, de inibição do crescimento ou morte de célula de câncer, para tratar indivíduo com câncer, para adaptar de terapia de câncer para indivíduo com câncer e para identificar antígeno específico de tumor
WO2012122649A1 (en) * 2011-03-15 2012-09-20 Ottawa Hospital Research Institute Recombinant orf virus
JP6415977B2 (ja) 2011-04-15 2018-10-31 ジェネラックス・コーポレイションGenelux Corporation 弱毒化ワクシニアウイルスのクローン株およびその使用方法
WO2013052915A2 (en) 2011-10-05 2013-04-11 Genelux Corporation Method for detecting replication or colonization of a biological therapeutic
WO2014160328A1 (en) 2013-03-13 2014-10-02 The Board Of Regents Of The University Of Texas System Mtor inhibitors for prevention of intestinal polyp growth
EP2971008B1 (en) 2013-03-14 2018-07-25 Salk Institute for Biological Studies Oncolytic adenovirus compositions
DE102013105144A1 (de) * 2013-05-17 2014-11-20 Arno Thaller Pharmazeutisches Kombinationspräparat mit einem anti-idiotypischen Antikörperfragment
US9700544B2 (en) 2013-12-31 2017-07-11 Neal K Vail Oral rapamycin nanoparticle preparations
AU2014373683B2 (en) 2013-12-31 2020-05-07 Rapamycin Holdings, Llc Oral rapamycin nanoparticle preparations and use
ES2841075T3 (es) 2014-10-24 2021-07-07 Calidi Biotherapeutics Inc Enfoque de inmunoterapia de combinación para el tratamiento del cáncer
CN107735103B (zh) 2015-02-25 2022-05-27 纪念斯隆-凯特琳癌症中心 使用灭活的非复制型的修饰的痘苗病毒安卡拉(mva)作为实体肿瘤的单一免疫疗法或与免疫检查点阻断剂的组合
CN116173193A (zh) 2015-04-17 2023-05-30 纪念斯隆凯特琳癌症中心 Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用
KR102201147B1 (ko) 2015-08-11 2021-01-11 카리디 바이오테라퓨틱스, 인크. 암 치료에 사용하기 위한 천연두 백신
BR112018013930A2 (pt) 2016-01-08 2018-12-11 Replimune Limited vírus oncolítico, vírus que expressa três genes heterólogos, composição farmacêutica, vírus para o uso, produto de fabricação, método de tratamento de câncer e uso do vírus
CN105754952B (zh) * 2016-02-16 2020-07-10 中国农业科学院兰州兽医研究所 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用
CA3013637A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
JP7015551B2 (ja) 2016-02-23 2022-02-15 ソーク インスティテュート フォー バイオロジカル スタディーズ ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現
AU2017222686B2 (en) 2016-02-25 2021-12-23 Memorial Sloan Kettering Cancer Center Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy
IL261321B2 (en) 2016-02-25 2023-12-01 Memorial Sloan Kettering Cancer Center Recombinant MVA or MVADELE3L expressing human FLT3L and their use as immunotherapeutic agents against solid tumors
US20200316146A1 (en) * 2016-03-25 2020-10-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Synthetically enveloped virus
WO2017205674A1 (en) * 2016-05-25 2017-11-30 Arizona Board Of Regents On Behalf Of Arizona State University Oncolytic vaccinia virus mutants and using same for cancer treatment
WO2018016917A1 (ko) * 2016-07-21 2018-01-25 코오롱생명과학 주식회사 재조합 백시니아 바이러스 및 이의 용도
CN110062630A (zh) 2016-12-12 2019-07-26 萨克生物研究学院 肿瘤靶向合成腺病毒及其用途
WO2018209315A1 (en) 2017-05-12 2018-11-15 Memorial Sloan Kettering Cancer Center Vaccinia virus mutants useful for cancer immunotherapy
US10610583B2 (en) 2017-08-31 2020-04-07 Regents Of The University Of Minnesota Methods and compositions for treating glioma and medulloblastoma brain tumors using the zika virus
KR102267837B1 (ko) * 2018-01-19 2021-06-22 코오롱생명과학 주식회사 재조합 백시니아 바이러스 및 이를 포함하는 약학 조성물
US11505782B2 (en) 2018-06-04 2022-11-22 Calidi Biotherapeutics, Inc. Cell-based vehicles for potentiation of viral therapy

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
CA2051289C (en) 1990-09-14 2002-11-26 Robert L. Martuza Viral mediated destruction of neoplastic cells
US5801029A (en) * 1993-02-16 1998-09-01 Onyx Pharmaceuticals, Inc. Cytopathic viruses for therapy and prophylaxis of neoplasia
US5585096A (en) 1994-06-23 1996-12-17 Georgetown University Replication-competent herpes simplex virus mediates destruction of neoplastic cells
WO1997012623A1 (en) 1995-10-06 1997-04-10 Arch Development Corporation Methods and compositions for viral enhancement of cell killing
AU2182697A (en) * 1996-03-29 1997-10-22 University Of Otago Parapoxvirus vectors
CA2255941A1 (en) 1996-05-31 1997-12-04 David L. Ennist Prevention of graft-versus-host disease with t-cells including polynucleotides encoding negative selective markers
JPH1087503A (ja) 1996-09-06 1998-04-07 Nippon Chem Res Kk 神経系腫瘍細胞のアポトーシス剤
FR2759614B1 (fr) 1997-02-19 1999-03-19 Ind Regionale Batiment Element de construction obtenu par moulage
DK0979098T3 (da) 1997-05-01 2003-07-14 Sod Conseils Rech Applic Fremgangsmåde til behandling af hyperprolaktinæmi og prolaktinomer
GB9708918D0 (en) 1997-05-01 1997-06-25 Ppl Therapeutics Scotland Ltd Methods
AU7285098A (en) 1997-05-06 1998-11-27 Kemin Industries, Inc. Anti-fungal protein extracts from seeds of marigold
JP2002513290A (ja) * 1997-05-08 2002-05-08 ジェネティック・セラピー・インコーポレテッド 修飾されたファイバー蛋白質を有するアデノウイルスによる遺伝子移入
US6136307A (en) * 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
ES2292207T3 (es) * 1997-10-09 2008-03-01 Wellstat Biologics Corporation Tratamiento de neoplasmas con virus clonales, sensibles al interferon.
EP1061806A4 (en) * 1998-03-12 2001-09-12 Univ Pennsylvania PRODUCTIVE CELLS FOR REPLICATION-SELECTIVE VIRUSES FOR TREATING Vicious DISEASES
WO1999055910A1 (en) 1998-04-24 1999-11-04 Arizona Board Of Regents Method of inducing apoptosis in a target cell
WO1999067372A1 (en) 1998-06-22 1999-12-29 The Board Of Trustees Of The University Of Arkansas Mutated herpes simplex virus type 1 thymidine kinases and uses thereof
US6428968B1 (en) 1999-03-15 2002-08-06 The Trustees Of The University Of Pennsylvania Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject
US6774119B1 (en) * 1999-04-26 2004-08-10 Cedars-Sinai Medical Center Herpes simplex virus type 1 (hsv-1)-derived vector for selectively inhibiting malignant cells and methods for its use to treat cancers and to express desired traits in malignant and non-malignant mammalian cells
EP1227828A1 (en) * 1999-11-12 2002-08-07 Oncolytics Biotech, Inc. Viruses for the treatment of cellular proliferative disorders
US6723316B2 (en) * 1999-12-22 2004-04-20 Onyx Pharmaceuticals, Inc. Herpes simplex virus-1 Glycoprotein C mutants for treating unwanted hyperproliferative cell growth

Similar Documents

Publication Publication Date Title
BE2016C018I2 (US06573293-20030603-C00009.png)
BE2014C035I2 (US06573293-20030603-C00009.png)
BE2010C018I2 (US06573293-20030603-C00009.png)
BE2010C019I2 (US06573293-20030603-C00009.png)
BE2010C008I2 (US06573293-20030603-C00009.png)
JP2003507142A5 (US06573293-20030603-C00009.png)
JP2002152187A5 (US06573293-20030603-C00009.png)
JP2003514024A5 (US06573293-20030603-C00009.png)
AR028236A3 (US06573293-20030603-C00009.png)
JP2003519023A5 (US06573293-20030603-C00009.png)
JP2000347835A5 (US06573293-20030603-C00009.png)
JP2001094615A5 (US06573293-20030603-C00009.png)
BRPI0113372A8 (US06573293-20030603-C00009.png)
JP2001223251A5 (US06573293-20030603-C00009.png)
JP2002011862A5 (US06573293-20030603-C00009.png)
JP2002162647A5 (US06573293-20030603-C00009.png)
BR0112866A2 (US06573293-20030603-C00009.png)
AU2000270908A8 (US06573293-20030603-C00009.png)
CN3145693S (US06573293-20030603-C00009.png)
AU2000271150A8 (US06573293-20030603-C00009.png)
CN3143422S (US06573293-20030603-C00009.png)
CN3141400S (US06573293-20030603-C00009.png)
CN3141017S (US06573293-20030603-C00009.png)
AU2000264849A8 (US06573293-20030603-C00009.png)
CN3141005S (US06573293-20030603-C00009.png)