JP2003510286A5 - - Google Patents
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- Publication number
- JP2003510286A5 JP2003510286A5 JP2001526191A JP2001526191A JP2003510286A5 JP 2003510286 A5 JP2003510286 A5 JP 2003510286A5 JP 2001526191 A JP2001526191 A JP 2001526191A JP 2001526191 A JP2001526191 A JP 2001526191A JP 2003510286 A5 JP2003510286 A5 JP 2003510286A5
- Authority
- JP
- Japan
- Prior art keywords
- ruhi
- emil
- thio
- monkey
- individual
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000282693 Cercopithecidae Species 0.000 description 18
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 18
- 206010012601 diabetes mellitus Diseases 0.000 description 14
- 230000002485 urinary effect Effects 0.000 description 14
- 102000009027 Albumins Human genes 0.000 description 9
- 108010088751 Albumins Proteins 0.000 description 9
- 102000004169 proteins and genes Human genes 0.000 description 9
- 108090000623 proteins and genes Proteins 0.000 description 9
- 206010027525 Microalbuminuria Diseases 0.000 description 8
- 235000008216 herbs Nutrition 0.000 description 7
- 208000007342 Diabetic Nephropathies Diseases 0.000 description 6
- 208000033679 diabetic kidney disease Diseases 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 238000011156 evaluation Methods 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 239000002207 metabolite Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000002253 acid Substances 0.000 description 4
- 210000002700 urine Anatomy 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 3
- 125000003396 thiol group Chemical class [H]S* 0.000 description 3
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 206010001580 Albuminuria Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/408,436 | 1999-09-29 | ||
| US09/408,436 US6149915A (en) | 1999-09-29 | 1999-09-29 | Treatment of diabetic nephropathy and microalbuminuria |
| PCT/US2000/025783 WO2001022981A1 (en) | 1999-09-29 | 2000-09-21 | Treatment of diabetic nephropathy and microalbuminuria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003510286A JP2003510286A (ja) | 2003-03-18 |
| JP2003510286A5 true JP2003510286A5 (enExample) | 2007-11-08 |
Family
ID=23616291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001526191A Pending JP2003510286A (ja) | 1999-09-29 | 2000-09-21 | 糖尿病性腎症および微量アルブミン尿症の治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6149915A (enExample) |
| EP (1) | EP1218020A1 (enExample) |
| JP (1) | JP2003510286A (enExample) |
| CN (1) | CN1387439A (enExample) |
| AU (1) | AU771275B2 (enExample) |
| CA (1) | CA2386000A1 (enExample) |
| WO (1) | WO2001022981A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6149915A (en) * | 1999-09-29 | 2000-11-21 | Shiva Biomedical, Llc | Treatment of diabetic nephropathy and microalbuminuria |
| DE10229180A1 (de) | 2002-06-28 | 2004-01-29 | Aventis Pharma Deutschland Gmbh | Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen |
| CN102579460B (zh) * | 2003-12-30 | 2015-04-29 | 麦仁斯有限公司 | 用增强代谢活性的丹参衍生物治疗肥胖和代谢综合症 |
| US8029829B2 (en) | 2005-02-03 | 2011-10-04 | Taiyo Kagaku Co., Ltd. | Preventive, relieving or therapeutic composition for diabetes mellitus and/or diabetic nephropathy |
| CN100341581C (zh) * | 2005-07-29 | 2007-10-10 | 上海第二医科大学附属第九人民医院 | 一种丹酚酸b有效干预口腔癌动物模型的方法 |
| US20070027209A1 (en) * | 2005-08-01 | 2007-02-01 | Lee Hyun C | Prevention and treatment of atherosclerosis with lithospermate B |
| WO2007102451A1 (ja) * | 2006-03-07 | 2007-09-13 | Nippon Shinyaku Co., Ltd. | 育毛剤 |
| US20100174097A1 (en) * | 2007-03-28 | 2010-07-08 | Man Kil Jung | Method for isolation of high concentration of magnesium lithospermate b from salviae miltiorrhizae |
| WO2011061749A2 (en) * | 2009-11-19 | 2011-05-26 | Ganga Raju Gokaraju | Agents derived from holoptelea integrifolia and their compositions for the control of metabolic syndrome and associated diseases |
| CN102550916A (zh) * | 2012-02-04 | 2012-07-11 | 王姗思 | 一种用于糖尿病肾病的食品 |
| CN102614267A (zh) * | 2012-04-24 | 2012-08-01 | 许风国 | 一种治疗糖尿病肾病的中药组合物及其制备方法 |
| CN103830496A (zh) * | 2014-02-28 | 2014-06-04 | 廊坊市思科农业技术有限公司 | 一种辅助降糖的组合物 |
| CN104974119B (zh) * | 2014-04-01 | 2018-10-19 | 中国科学院上海药物研究所 | 一种高纯度丹酚酸b镁及其制备方法 |
| CN104547498A (zh) * | 2014-12-31 | 2015-04-29 | 黎细乐 | 一种中药组合物的新用途 |
| US20160361288A1 (en) * | 2015-06-10 | 2016-12-15 | Postech Academy-Industry Foundation | Pharmaceutical compositions for preventing or treating diabetic nephropathy comprising the activity inhibitor of tenc1 |
| CN105311413A (zh) * | 2015-11-18 | 2016-02-10 | 暨南大学 | 治疗糖尿病肾病的含有艾叶的中药组合物及其制备方法 |
| CN107551172A (zh) * | 2017-10-26 | 2018-01-09 | 马雪英 | 一种治疗肾病综合症的药物及其制备方法 |
| CN110215449A (zh) * | 2019-05-13 | 2019-09-10 | 中国科学院长春应用化学研究所 | 紫草酸在抑制胰岛素淀粉样多肽聚集中的应用 |
| CN112190646B (zh) * | 2020-11-19 | 2021-12-28 | 首都医科大学附属北京中医医院 | 一种治疗糖尿病肾病的中药组合物及其制备方法 |
| CN112569313B (zh) * | 2020-12-28 | 2022-02-22 | 贵州三力制药股份有限公司 | 治疗肾病的中药组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01268682A (ja) * | 1988-04-21 | 1989-10-26 | Minofuaagen Seiyaku Honpo:Goushi | 腎機能改善剤及びリソスペルミン酸塩の製造方法 |
| US5358962A (en) * | 1993-04-22 | 1994-10-25 | Minophagen Pharmaceutical Company | Antihypertensive method |
| JP3638967B2 (ja) * | 1993-06-03 | 2005-04-13 | 日本ケミカルリサーチ株式会社 | ネフローゼ症候群及び肝障害症状の寛解剤 |
| JP3161882B2 (ja) * | 1993-06-03 | 2001-04-25 | 日本ケミカルリサーチ株式会社 | 丹参由来多糖類、その製造法および用途 |
| US5547945A (en) * | 1993-07-15 | 1996-08-20 | Jcr Pharmaceuticals Co., Ltd. | Remitting agent for nephrotic syndrome and hepatopathy symptoms |
| US6149915A (en) * | 1999-09-29 | 2000-11-21 | Shiva Biomedical, Llc | Treatment of diabetic nephropathy and microalbuminuria |
-
1999
- 1999-09-29 US US09/408,436 patent/US6149915A/en not_active Expired - Fee Related
-
2000
- 2000-09-21 CN CN00815232A patent/CN1387439A/zh active Pending
- 2000-09-21 JP JP2001526191A patent/JP2003510286A/ja active Pending
- 2000-09-21 US US09/666,623 patent/US6267992B1/en not_active Expired - Fee Related
- 2000-09-21 CA CA002386000A patent/CA2386000A1/en not_active Abandoned
- 2000-09-21 EP EP0096366100963661A patent/EP1218020A1/en not_active Withdrawn
- 2000-09-21 AU AU40235/01A patent/AU771275B2/en not_active Ceased
- 2000-09-21 WO PCT/US2000/025783 patent/WO2001022981A1/en not_active Ceased
-
2001
- 2001-06-20 US US09/885,523 patent/US20020025347A1/en not_active Abandoned
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