JP2003510032A5 - - Google Patents
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- Publication number
- JP2003510032A5 JP2003510032A5 JP2001519732A JP2001519732A JP2003510032A5 JP 2003510032 A5 JP2003510032 A5 JP 2003510032A5 JP 2001519732 A JP2001519732 A JP 2001519732A JP 2001519732 A JP2001519732 A JP 2001519732A JP 2003510032 A5 JP2003510032 A5 JP 2003510032A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- polypeptide
- gene
- cells
- syncytium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000623 proteins and genes Proteins 0.000 claims 47
- 102000004169 proteins and genes Human genes 0.000 claims 31
- 229920001184 polypeptide Polymers 0.000 claims 25
- 102000004196 processed proteins & peptides Human genes 0.000 claims 25
- 108090000765 processed proteins & peptides Proteins 0.000 claims 25
- 210000004027 cell Anatomy 0.000 claims 22
- 239000013598 vector Substances 0.000 claims 15
- 230000015572 biosynthetic process Effects 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 13
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 230000001225 therapeutic effect Effects 0.000 claims 11
- 230000007547 defect Effects 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 9
- 239000003795 chemical substances by application Substances 0.000 claims 8
- 206010028980 Neoplasm Diseases 0.000 claims 7
- 201000011510 cancer Diseases 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 238000004113 cell culture Methods 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 4
- 230000000799 fusogenic effect Effects 0.000 claims 4
- 238000001415 gene therapy Methods 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 4
- 102100021696 Syncytin-1 Human genes 0.000 claims 3
- 230000028742 placenta development Effects 0.000 claims 3
- 230000000069 prophylactic effect Effects 0.000 claims 3
- 230000017960 syncytium formation Effects 0.000 claims 3
- 210000001519 tissue Anatomy 0.000 claims 3
- 101710091045 Envelope protein Proteins 0.000 claims 2
- 241000713887 Human endogenous retrovirus Species 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 101710188315 Protein X Proteins 0.000 claims 2
- 230000000692 anti-sense effect Effects 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 230000007170 pathology Effects 0.000 claims 2
- 229940002612 prodrug Drugs 0.000 claims 2
- 239000000651 prodrug Substances 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 101000820777 Homo sapiens Syncytin-1 Proteins 0.000 claims 1
- 241000005822 Human endogenous retrovirus W Species 0.000 claims 1
- 108700026244 Open Reading Frames Proteins 0.000 claims 1
- 210000002449 bone cell Anatomy 0.000 claims 1
- 210000000349 chromosome Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000018109 developmental process Effects 0.000 claims 1
- 230000008034 disappearance Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 108700004025 env Genes Proteins 0.000 claims 1
- 101150030339 env gene Proteins 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 230000002185 fusiogenic effect Effects 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 210000000663 muscle cell Anatomy 0.000 claims 1
- 210000004498 neuroglial cell Anatomy 0.000 claims 1
- 210000002826 placenta Anatomy 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 230000001177 retroviral effect Effects 0.000 claims 1
- 241001430294 unidentified retrovirus Species 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR99/11141 | 1999-09-01 | ||
| FR9911141A FR2797888A1 (fr) | 1999-09-01 | 1999-09-01 | Procede de detection de l'expression d'une proteine d'enveloppe d'un retrovirus endogene humain et utilisations d'un gene codant pour cette proteine |
| FR99/11793 | 1999-09-15 | ||
| FR9911793A FR2797889A1 (fr) | 1999-09-01 | 1999-09-15 | Procede de detection de l'expression d'une proteine d'enveloppe d'un retrovirus endogene humain et utilisations d'un gene codant pour cette proteine |
| PCT/FR2000/002429 WO2001016171A1 (fr) | 1999-09-01 | 2000-09-01 | Procede de detection de l'expression d'une proteine d'enveloppe d'un retrovirus endogene humain et utilisations d'un gene codant pour cette proteine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008244988A Division JP4824731B2 (ja) | 1999-09-01 | 2008-09-24 | ヒト内因性レトロウイルスのエンベロープタンパク質の発現を検出する方法、並びに上記タンパク質をコードする遺伝子の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003510032A JP2003510032A (ja) | 2003-03-18 |
| JP2003510032A5 true JP2003510032A5 (https=) | 2005-02-17 |
| JP4283475B2 JP4283475B2 (ja) | 2009-06-24 |
Family
ID=26235097
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001519732A Expired - Lifetime JP4283475B2 (ja) | 1999-09-01 | 2000-09-01 | ヒト内因性レトロウイルスのエンベロープタンパク質の発現を検出する方法、並びに上記タンパク質をコードする遺伝子の使用 |
| JP2008244988A Expired - Lifetime JP4824731B2 (ja) | 1999-09-01 | 2008-09-24 | ヒト内因性レトロウイルスのエンベロープタンパク質の発現を検出する方法、並びに上記タンパク質をコードする遺伝子の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008244988A Expired - Lifetime JP4824731B2 (ja) | 1999-09-01 | 2008-09-24 | ヒト内因性レトロウイルスのエンベロープタンパク質の発現を検出する方法、並びに上記タンパク質をコードする遺伝子の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7442550B1 (https=) |
| EP (2) | EP2385058B1 (https=) |
| JP (2) | JP4283475B2 (https=) |
| AT (1) | ATE531726T1 (https=) |
| AU (1) | AU7297100A (https=) |
| CA (1) | CA2383877C (https=) |
| ES (2) | ES2376726T3 (https=) |
| FR (1) | FR2797889A1 (https=) |
| WO (1) | WO2001016171A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002004678A2 (en) * | 2000-07-07 | 2002-01-17 | Genetics Institute, Llc. | Methods and compositions for diagnosing and treating preeclampsia and gestational trophoblast disorders |
| EP1651667B1 (en) | 2003-04-04 | 2012-03-28 | Centre National De La Recherche Scientifique | Protein with fusogenic activity, nucleic acid sequences encoding said protein and pharmaceutical compositions comprising the same |
| FR2865403B1 (fr) * | 2004-01-23 | 2009-06-12 | Biomerieux Sa | Composition pour le traitement d'une pathologie associee a la msrv/herv-w |
| DK1871391T3 (da) * | 2005-03-30 | 2012-04-16 | Viroxis | Endogen retrovirus og proteiner, der kodes af env som target for cancerbehandling |
| WO2009088256A2 (ko) * | 2008-01-09 | 2009-07-16 | Konkuk University Industrial Cooperation Corp | 배큘로바이러스-기반 백신 |
| EP3235828A1 (en) | 2016-04-21 | 2017-10-25 | Genethon | Stable pseudotyped lentiviral particles and uses thereof |
| IL273923B2 (en) | 2017-10-20 | 2024-08-01 | Genethon | Using syncytin for drug targeting and gene delivery to lung tissue |
| CA3078096A1 (en) | 2017-10-20 | 2018-10-19 | Genethon | Use of syncytin for targeting drug and gene delivery to regenerating muscle tissue |
| AU2019343045A1 (en) | 2018-09-18 | 2021-05-13 | Vnv Newco Inc. | ARC-based capsids and uses thereof |
| US11129892B1 (en) | 2020-05-18 | 2021-09-28 | Vnv Newco Inc. | Vaccine compositions comprising endogenous Gag polypeptides |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2663040B1 (fr) | 1990-06-11 | 1995-09-15 | Bio Merieux | Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich. |
| US6312921B1 (en) * | 1996-07-26 | 2001-11-06 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| AU8447098A (en) * | 1997-07-07 | 1999-02-08 | Bio Merieux | Endogenetic retroviral sequences, associated with autoimmune diseases or with pregnancy disorders |
| CA2328489A1 (en) * | 1998-05-18 | 1999-11-25 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
-
1999
- 1999-09-15 FR FR9911793A patent/FR2797889A1/fr not_active Withdrawn
-
2000
- 2000-09-01 ES ES00960783T patent/ES2376726T3/es not_active Expired - Lifetime
- 2000-09-01 ES ES10183612.0T patent/ES2444649T3/es not_active Expired - Lifetime
- 2000-09-01 WO PCT/FR2000/002429 patent/WO2001016171A1/fr not_active Ceased
- 2000-09-01 US US10/069,883 patent/US7442550B1/en not_active Expired - Lifetime
- 2000-09-01 AT AT00960783T patent/ATE531726T1/de active
- 2000-09-01 CA CA2383877A patent/CA2383877C/fr not_active Expired - Lifetime
- 2000-09-01 EP EP10183612.0A patent/EP2385058B1/fr not_active Expired - Lifetime
- 2000-09-01 EP EP00960783A patent/EP1212359B1/fr not_active Expired - Lifetime
- 2000-09-01 JP JP2001519732A patent/JP4283475B2/ja not_active Expired - Lifetime
- 2000-09-01 AU AU72971/00A patent/AU7297100A/en not_active Abandoned
-
2008
- 2008-09-24 JP JP2008244988A patent/JP4824731B2/ja not_active Expired - Lifetime
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