JP2003508484A5 - - Google Patents
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- JP2003508484A5 JP2003508484A5 JP2001521308A JP2001521308A JP2003508484A5 JP 2003508484 A5 JP2003508484 A5 JP 2003508484A5 JP 2001521308 A JP2001521308 A JP 2001521308A JP 2001521308 A JP2001521308 A JP 2001521308A JP 2003508484 A5 JP2003508484 A5 JP 2003508484A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- day
- composition according
- metabolite
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- 239000002207 metabolite Substances 0.000 claims 12
- 201000011510 cancer Diseases 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- JIWBIWFOSCKQMA-LTKCOYKYSA-N Stearidonic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/CCCCC(O)=O JIWBIWFOSCKQMA-LTKCOYKYSA-N 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 150000003626 triacylglycerols Chemical class 0.000 claims 2
- YEKFYCQGYMVFKR-MBFZXKRTSA-N (2E,4E,6E,8E,10E)-docosa-2,4,6,8,10-pentaenoic acid Chemical compound CCCCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C(O)=O YEKFYCQGYMVFKR-MBFZXKRTSA-N 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 235000021294 Docosapentaenoic acid Nutrition 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 150000007942 carboxylates Chemical class 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- IQLUYYHUNSSHIY-UHFFFAOYSA-N icosa-2,4,6,8-tetraenoic acid Chemical compound CCCCCCCCCCCC=CC=CC=CC=CC(O)=O IQLUYYHUNSSHIY-UHFFFAOYSA-N 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N α-linolenic acid Chemical class CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/393,790 US6340705B1 (en) | 1999-09-10 | 1999-09-10 | Use of α-linolenic acid metabolites for treatment or prevention of cancer |
US09/393,790 | 1999-09-10 | ||
PCT/US2000/024931 WO2001017517A2 (en) | 1999-09-10 | 2000-09-11 | Use of g(a)-linolenic acid metabolites in the manufacture of a medicament for the treatment or prevention of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2003508484A JP2003508484A (ja) | 2003-03-04 |
JP2003508484A5 true JP2003508484A5 (US07794700-20100914-C00152.png) | 2005-05-26 |
Family
ID=23556262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001521308A Pending JP2003508484A (ja) | 1999-09-10 | 2000-09-11 | がん治療または予防のためのα−リノレン酸代謝物の使用 |
Country Status (9)
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040037892A1 (en) * | 2001-11-19 | 2004-02-26 | Adrianne Bendich | Dietary composition containing conjugated linoleic acid and calcium for improved health |
WO2002092779A2 (en) * | 2001-05-17 | 2002-11-21 | Pilot Therapeutics, Inc. | Method for enriching tissues in long chain polyunsaturated fatty acids |
US6977271B1 (en) * | 2001-08-30 | 2005-12-20 | Health Research, Inc. | Method for inhibition of angiogenesis and vasculogenesis |
GB0311081D0 (en) * | 2003-05-14 | 2003-06-18 | Btg Internat Limted | Treatment of neurodegenerative conditions |
CA2436650A1 (en) * | 2003-08-06 | 2005-02-06 | Naturia Inc. | Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses |
DE112004001520B4 (de) * | 2003-08-18 | 2008-04-10 | Btg International Ltd. | Verwendung eines Lipidglyzerids festgelegter Struktur zur Herstellung eines Medikamentes zur Behandlung der multiplen Sklerose |
GEP20094679B (en) * | 2004-03-15 | 2009-05-10 | Takeda Pharmaceuticals Co | Dipeptidyl peptidase inhibitors |
US20050266051A1 (en) * | 2004-05-27 | 2005-12-01 | The Procter & Gamble Company | Pet food compositions and methods |
US7456270B2 (en) | 2004-09-01 | 2008-11-25 | Abbott Laboratories | Δ6-desaturase genes and uses thereof |
GB0425932D0 (en) * | 2004-11-25 | 2004-12-29 | Btg Int Ltd | Structured phospholipids |
US8092839B2 (en) * | 2004-12-13 | 2012-01-10 | Swing Aerobics Licensing, Inc. | Medicament for treatment of cancer and other diseases |
US8431165B2 (en) * | 2004-12-13 | 2013-04-30 | Swing Aerobics Licensing, Inc. | Medicament for treatment of cancer and other diseases |
GB0504333D0 (en) * | 2005-03-02 | 2005-04-06 | Btg Int Ltd | Treatment of cytokine dysregulation |
GB0504362D0 (en) * | 2005-03-02 | 2005-04-06 | Btg Int Ltd | Cytokine modulators |
US7481870B2 (en) * | 2006-04-18 | 2009-01-27 | Oreck Holdings, Llc | Electrode wire for an electrostatic precipitator |
JP2009538900A (ja) | 2006-06-08 | 2009-11-12 | ザ アイムス カンパニー | 眼の健康を増進するための少なくとも一つのポリフェノールの使用 |
FR2904554B1 (fr) * | 2006-08-04 | 2010-11-05 | Zheng Xu | Lipides moleculaires heterogenes cytotropes (lmhc), procede de preparation, et methodes de traitement de patients porteurs de cancers multiples |
US8343753B2 (en) * | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
CA2704371A1 (en) * | 2007-11-01 | 2009-05-07 | Wake Forest University School Of Medicine | Compositions and methods for prevention and treatment of mammalian diseases |
TWI448290B (zh) * | 2007-12-19 | 2014-08-11 | Prometic Biosciences Inc | 與健擇他濱(gemcitabine)組合用於胰臟癌之治療的中等鏈長脂肪酸、鹽類及三酸甘油酯 |
US20090197955A1 (en) * | 2008-01-31 | 2009-08-06 | Monsanto Company | Methods of improving dha deposition and related function and/or development |
US8060617B2 (en) * | 2008-12-19 | 2011-11-15 | Cisco Technology, Inc. | Reserving network resources during scheduling of meeting event |
US8372465B2 (en) | 2010-02-17 | 2013-02-12 | Bunge Oils, Inc. | Oil compositions of stearidonic acid |
EP2425833A1 (de) * | 2010-09-03 | 2012-03-07 | Fresenius Kabi Deutschland GmbH | Die intravenöse Applikation von Fischöl/DHA +EPA vor bzw. mit Beginn der Chemotherapie |
WO2012141575A1 (en) * | 2011-04-14 | 2012-10-18 | N.V.Nutricia | Combination of epa, dpa and/or dha with a chemotherapeutic agent |
US10076550B2 (en) * | 2014-06-25 | 2018-09-18 | Council Of Scientific & Industrial Research | Synergistic pharmaceutical composition for gastroinestinal disorders |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8302708D0 (en) | 1983-02-01 | 1983-03-02 | Efamol Ltd | Pharmaceutical and dietary composition |
HU203660B (en) * | 1987-04-23 | 1991-09-30 | Biogal Gyogyszergyar | Improved process for producing food-additive composition rich in omega-3-unsaturated fatty acids |
CN1035925C (zh) * | 1988-11-16 | 1997-09-24 | 许正 | 亲细胞非均质分子脂质的制备方法 |
DK0457950T3 (da) * | 1990-05-23 | 1994-03-07 | Nestle Sa | Anvendelse af stearidonsyre til behandling af inflammatorisk betingede sygdomme |
GB9012651D0 (en) * | 1990-06-06 | 1990-07-25 | Efamol Holdings | Essential fatty acid treatment |
EP0585058A1 (en) * | 1992-08-25 | 1994-03-02 | Scotia Holdings Plc | Pharmaceutical compositions containing fatty acids and heparin |
EP0585057A1 (en) * | 1992-08-25 | 1994-03-02 | Scotia Holdings Plc | Lithium salts of fatty acids for the treatment of viral infections and cancer |
CA2119000A1 (en) | 1993-03-19 | 1994-09-20 | David Frederick Horrobin | Formulation for use in smokers |
US5925669A (en) * | 1994-03-22 | 1999-07-20 | Molecular/Structural Bio Technologies, Inc. | Carrier compositions for anti-neoplastic drugs |
JPH0853351A (ja) * | 1994-08-11 | 1996-02-27 | Sagami Chem Res Center | 酵素阻害剤、血管新生抑制剤、および癌転移抑制剤 |
KR970002037B1 (ko) * | 1994-12-09 | 1997-02-21 | 농촌진흥청 | 들깨유로부터 α-리놀렌산(ALA)을 분리, 정제하는 방법 |
US5639787A (en) * | 1995-02-28 | 1997-06-17 | The Center For The Improvement Of Human Functioning Int'l, Inc. | Therapeutic method for the treatment of cancer |
US6077828A (en) | 1996-04-25 | 2000-06-20 | Abbott Laboratories | Method for the prevention and treatment of cachexia and anorexia |
ES2179156T3 (es) | 1996-11-20 | 2003-01-16 | Nutricia Nv | Composicion nutricional que incluye grasas para el tratamiento del sindrome metabolico. |
DE19757414A1 (de) * | 1997-12-23 | 1999-07-01 | Nutricia Nv | Fettmischung |
-
1999
- 1999-09-10 US US09/393,790 patent/US6340705B1/en not_active Expired - Lifetime
-
2000
- 2000-09-11 AU AU73716/00A patent/AU7371600A/en not_active Abandoned
- 2000-09-11 AT AT00961816T patent/ATE318133T1/de not_active IP Right Cessation
- 2000-09-11 WO PCT/US2000/024931 patent/WO2001017517A2/en active IP Right Grant
- 2000-09-11 EP EP00961816A patent/EP1237545B1/en not_active Expired - Lifetime
- 2000-09-11 JP JP2001521308A patent/JP2003508484A/ja active Pending
- 2000-09-11 DE DE60026152T patent/DE60026152T2/de not_active Expired - Lifetime
- 2000-09-11 MX MXPA02002681A patent/MXPA02002681A/es active IP Right Grant
- 2000-09-11 CA CA2384502A patent/CA2384502C/en not_active Expired - Fee Related
-
2001
- 2001-07-13 US US09/903,707 patent/US20020010211A1/en not_active Abandoned
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