JP2003506396A - 水性経鼻製剤 - Google Patents

水性経鼻製剤

Info

Publication number
JP2003506396A
JP2003506396A JP2001514930A JP2001514930A JP2003506396A JP 2003506396 A JP2003506396 A JP 2003506396A JP 2001514930 A JP2001514930 A JP 2001514930A JP 2001514930 A JP2001514930 A JP 2001514930A JP 2003506396 A JP2003506396 A JP 2003506396A
Authority
JP
Japan
Prior art keywords
formulation
anhydrous
pharmaceutical preparation
beclomethasone dipropionate
polyoxyethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001514930A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003506396A5 (https=
Inventor
理香 阿久津
憲司 細谷
橿保 河村
泰宏 三島
友久 小野崎
伸弥 杉林
Original Assignee
グラクソ・ウエルカム株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by グラクソ・ウエルカム株式会社 filed Critical グラクソ・ウエルカム株式会社
Publication of JP2003506396A publication Critical patent/JP2003506396A/ja
Publication of JP2003506396A5 publication Critical patent/JP2003506396A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2001514930A 1999-08-07 2000-08-03 水性経鼻製剤 Pending JP2003506396A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9918559.7A GB9918559D0 (en) 1999-08-07 1999-08-07 Novel pharmaceutical formulation
GB9918559.7 1999-08-07
PCT/JP2000/005200 WO2001010409A1 (en) 1999-08-07 2000-08-03 Aqueous nasal formulation

Publications (2)

Publication Number Publication Date
JP2003506396A true JP2003506396A (ja) 2003-02-18
JP2003506396A5 JP2003506396A5 (https=) 2007-09-20

Family

ID=10858698

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001514930A Pending JP2003506396A (ja) 1999-08-07 2000-08-03 水性経鼻製剤

Country Status (9)

Country Link
US (1) US6780398B1 (https=)
EP (1) EP1200066B1 (https=)
JP (1) JP2003506396A (https=)
AT (1) ATE240717T1 (https=)
AU (1) AU6471500A (https=)
DE (1) DE60002885T2 (https=)
ES (1) ES2199845T3 (https=)
GB (1) GB9918559D0 (https=)
WO (1) WO2001010409A1 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006523629A (ja) * 2003-04-16 2006-10-19 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 鼻用医薬製剤およびその使用方法
US8129364B2 (en) 2003-04-16 2012-03-06 Dey Pharma, L.P. Formulations and methods for treating rhinosinusitis
JP2012533554A (ja) * 2009-07-17 2012-12-27 アルコン リサーチ， リミテッド 小児のためのオロパタジン経鼻噴霧剤レジメン
JP2013082752A (ja) * 2007-05-25 2013-05-09 Rohto Pharmaceutical Co Ltd フルニソリド含有粘膜適用組成物
US9808471B2 (en) 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
JP2019031551A (ja) * 2011-08-25 2019-02-28 イヴォーク ファーマ，インク 女性胃不全麻痺に関係する症状の処置
US11020361B2 (en) 2008-12-22 2021-06-01 Evoke Pharma, Inc. Nasal formulations of metoclopramide
US11517545B2 (en) 2016-12-15 2022-12-06 Evoke Pharma, Inc. Treatment of moderate and severe gastroparesis

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US20050147584A1 (en) * 2004-01-05 2005-07-07 Allergan, Inc. Compositions and methods comprising memantine and polyanionic polymers
ITMI20032054A1 (it) * 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
CA2550811C (en) * 2003-12-24 2012-05-01 Jane Hirsh Temperature-stable formulations, and methods of development thereof
EP1645266A1 (en) * 2004-10-08 2006-04-12 Hisamitsu Medical Co., Ltd. Aqueous suspension for nasal drops
US20060207596A1 (en) * 2005-03-18 2006-09-21 Fairfield Clinical Trials, Llc Device and method for delivery of combination nasal medication
CN100369608C (zh) * 2006-03-15 2008-02-20 修涞贵 一种治疗过敏性鼻炎的混悬液型喷雾剂及制备方法
EP2736491B1 (en) * 2011-01-04 2017-04-05 Bausch & Lomb Incorporated Bepotastine compositions
EP2704687B1 (en) * 2011-05-04 2015-07-08 Chiesi Farmaceutici S.p.A. A topical formulation comprising a corticosteroid as active ingredient
WO2013049538A1 (en) * 2011-09-30 2013-04-04 Mcneil-Ppc, Inc. Allergen nasal compositions
WO2013049539A1 (en) * 2011-09-30 2013-04-04 Mcneil-Ppc, Inc. A method of blocking or trapping allergens
AU2022323269A1 (en) * 2021-08-04 2024-02-29 Indivior Inc. Compositions and methods for the treatment of opioid overdose
WO2025017382A1 (en) * 2023-07-15 2025-01-23 Aodh Lifesciences Private Limited Azithromycin nasal spray formulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62283927A (ja) * 1986-05-22 1987-12-09 シンテックス・ファーマシューティカルズ・インターナショナル・リミテッド 経鼻投与用水性ステロイド製剤
EP0780127A1 (en) * 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
WO1997046243A1 (en) * 1996-06-04 1997-12-11 The Procter & Gamble Company A nasal spray containing an intranasal steroid and an antihistamine
JP2002509797A (ja) * 1998-03-31 2002-04-02 ザ、プロクター、エンド、ギャンブル、カンパニー エラストマー弁を備えた鼻腔スプレー装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62283927A (ja) * 1986-05-22 1987-12-09 シンテックス・ファーマシューティカルズ・インターナショナル・リミテッド 経鼻投与用水性ステロイド製剤
EP0780127A1 (en) * 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
WO1997046243A1 (en) * 1996-06-04 1997-12-11 The Procter & Gamble Company A nasal spray containing an intranasal steroid and an antihistamine
JP2002509797A (ja) * 1998-03-31 2002-04-02 ザ、プロクター、エンド、ギャンブル、カンパニー エラストマー弁を備えた鼻腔スプレー装置

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
US8663695B2 (en) 2003-04-16 2014-03-04 Mylan Specialty L.P. Formulations and methods for treating rhinosinusitis
US8129364B2 (en) 2003-04-16 2012-03-06 Dey Pharma, L.P. Formulations and methods for treating rhinosinusitis
US9180126B2 (en) 2003-04-16 2015-11-10 Mylan Specialty L.P. Formulations and methods for treating rhinosinusitis
US8309061B2 (en) 2003-04-16 2012-11-13 Dey Pharma, L.P. Formulations and methods for treating rhinosinusitis
JP2006523629A (ja) * 2003-04-16 2006-10-19 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 鼻用医薬製剤およびその使用方法
US8158154B2 (en) 2003-04-16 2012-04-17 Dey Pharma, L.P. Nasal pharmaceutical formulations and methods of using the same
US9808471B2 (en) 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US7972627B2 (en) 2003-04-16 2011-07-05 Merck Patent Gmbh Beclomethasone dipropionate monohydrate nasal pharmaceutical formulations and methods of using the same
JP2013082752A (ja) * 2007-05-25 2013-05-09 Rohto Pharmaceutical Co Ltd フルニソリド含有粘膜適用組成物
US11813231B2 (en) 2008-12-22 2023-11-14 Evoke Pharma, Inc. Nasal formulations of metoclopramide
US12194009B2 (en) 2008-12-22 2025-01-14 Evoke Pharma, Inc. Nasal formulations of metoclopramide
US11020361B2 (en) 2008-12-22 2021-06-01 Evoke Pharma, Inc. Nasal formulations of metoclopramide
US12194008B2 (en) 2008-12-22 2025-01-14 Evoke Pharma, Inc. Nasal formulations of metoclopramide
US11628150B2 (en) 2008-12-22 2023-04-18 Evoke Pharma, Inc. Nasal formulations of metoclopramide
JP2012533554A (ja) * 2009-07-17 2012-12-27 アルコン リサーチ， リミテッド 小児のためのオロパタジン経鼻噴霧剤レジメン
JP2019031551A (ja) * 2011-08-25 2019-02-28 イヴォーク ファーマ，インク 女性胃不全麻痺に関係する症状の処置
US11517545B2 (en) 2016-12-15 2022-12-06 Evoke Pharma, Inc. Treatment of moderate and severe gastroparesis
US12377064B2 (en) 2016-12-15 2025-08-05 Evoke Pharma, Inc. Treatment of moderate and severe gastroparesis

Also Published As

Publication number Publication date
AU6471500A (en) 2001-03-05
DE60002885T2 (de) 2004-03-11
DE60002885D1 (de) 2003-06-26
GB9918559D0 (en) 1999-10-06
WO2001010409A1 (en) 2001-02-15
ATE240717T1 (de) 2003-06-15
US6780398B1 (en) 2004-08-24
EP1200066A1 (en) 2002-05-02
ES2199845T3 (es) 2004-03-01
EP1200066B1 (en) 2003-05-21

Similar Documents

Publication Publication Date Title
JP2003506396A (ja) 水性経鼻製剤
JP7492548B2 (ja) アルコール使用障害の処置のための組成物、装置、及び、方法
JP3480736B2 (ja) 気道流路および肺疾患の処置のためのモメタゾンフロエートの使用
RU2769397C2 (ru) Композиции и способы лечения передозировки опиоидами
RU2327450C2 (ru) Фармацевтические продукты и композиции, содержащие специфические антихолинергические средства, агонисты бета-2 и кортикостероиды
US6428769B1 (en) Acute testosterone administration
JP2002517450A (ja) 喘息の急性状態の予防または処置のための、ホルモテロールおよびブデソニドを含んでなる組成物の使用
EP1216046B1 (de) Neue kombination von loteprednol und antihistaminika
JP2003501404A (ja) 薬剤の脱水粒子からなる製剤およびこれの調製方法
JP2003511417A (ja) 局所的鼻疾患治療
JP2002501884A (ja) 点鼻用液剤
WO2010126818A1 (en) Intranasal delivery system for dantrolene
JP2008110991A (ja) 処置方法
JP2024164155A (ja) 過剰摂取および報酬に基づく障害を処置するための、組成物、装置、および方法
US20240408004A1 (en) Compositions, devices, and methods for the treatment of overdose and reward-based disorders
WO1996010991A1 (en) Pharmaceutical composition containing derivatives of sex hormones
US20200390691A1 (en) Compositions, devices, and methods for the treatment of overdose and reward-based disorders
US20240408003A1 (en) Compositions, devices and methods for the treatment of alcohol use disorder
CA2294785A1 (en) Low dosed 15-desoxyspergualine preparations
EP1175204A1 (en) Aerosol formulations and devices for increasing libido in women via acute testosterone administration

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070802

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070802

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110214

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20111108