JP2003503335A - Cosmetic composition - Google Patents

Abstract

  (57) [Summary] According to the present invention, there is provided a cosmetic composition comprising (a) at least one quaternary ammonium agent, and (b) at least one sunscreen active. The compositions of the present invention provide the benefits of a low sticky or non-greasy sunscreen. Further, the compositions of the present invention can provide excellent skin care benefits with low levels of disadvantages such as greasy, sticky or sticky.

Description

Detailed Description of the Invention

TECHNICAL FIELD The present invention relates to cosmetic compositions. In particular, the present invention provides excellent moisturization, hydration, skin feel, skin flexibility and / or protection against UV damage to the skin.
Or to a cosmetic composition that provides skin smoothness benefits.

BACKGROUND OF THE INVENTION The skin is made up of several layers of cells, covering and protecting the keratin and collagenous proteins that form the scaffold of its structure. The outermost part of these layers is called the stratum corneum, and
It is known to consist of a bundle of 25 nm proteins surrounded by layers of thickness nm. Anionic surfactants and organic solvents typically pass through the membranes of the stratum corneum and degrease (ie, remove lipids from the stratum corneum), destroying their integrity. This disruption of the skin surface topography causes a gritty feeling, and eventually,
Surfactants or organic solvents are allowed to interact with the keratin, causing inflammation. Many people expose their skin daily to the cause of this type of disorder.
Further, environmental factors such as exposure to cold or wind, mechanical exfoliation, water immersion, etc. can damage the skin. However, the most common form of environmental skin damage relates to exposure to ultraviolet radiation, especially radiation originating from the sun. Therefore, methods are needed to mitigate or ameliorate this damage.

Compositions traditionally thought to help the stratum corneum to retain barrier and water retention functions in optimal performance, despite the harmful interactions that the skin may encounter during cleaning, work and recreation. Things have been compounded. Desirable properties of such compositions are that they have excellent skin feel, water retention, moisture retention, absorption, and / or rub-in properties. Prior art compositions have attempted to ensure these properties through the use of one or more "skin benefit agents". For example, one way to impart high moisturizing properties to the skin is to incorporate polyhydric alcohol-like moisturizing substances such as glycerin into the composition. However, consumers often find that high levels of polyhydric alcohols, and thus skin compositions with high levels of moisturizing, are unpleasant when applied to the skin due to the feeling of stickiness. Another way to impart the desired skin benefit to the skin is to incorporate emollient materials such as polyol carboxylic acid esters into the skin care composition. However, such compositions are associated with unpleasant drawbacks in terms of skin feel (ie, they often give a very greasy feel on the skin) and with poor rubbing, absorption and residue properties.

It has been found that there is a direct relationship between the amount of skin benefit agent and the effectiveness of the composition in providing skin benefit. However, the higher the concentration of skin benefit agent, the higher the risk of associated drawbacks may be. Therefore, to date, it has been necessary to balance the benefits of compositions containing high levels of skin benefit agents against the drawbacks associated with such high levels. As a result, it contains high levels of skin benefit agents, thus providing high levels of moisturizing and hydration and benefits associated with high levels such as excellent skin feel, skin softness and skin smoothness. There remains a need for compositions that exhibit low levels of associated disorders such as, greasiness, stickiness or stickiness.

Quaternary ammonium agents are well known for use in cosmetic compositions. For example, WO-A-99 / 27904, WO-A-96 / 32089 and EP-A.
See -789,076. US-A-5,804,205 also discloses a skin care composition that is said to provide a high level of moisturizing properties without leaving a "greasy" or "sticky" residue. The composition comprises a quaternary ammonium compound having two alkyl groups with 16 to 22 carbon atoms, a humectant and 5
It contains non-irritating hydrophobic microspheres with an average particle size of less than 0 μm.
The hydrophobic polymer microspheres are "sticky" associated with high levels of moisturizers.
Claim to significantly reduce The composition of US-A-5,804,205 may also contain low levels of emollients such as petrolatum or mineral oil.

Materials that provide protection against sun damage are also well known for use in cosmetic compositions. For example, EP-A-992455, EP-A-95333.
6, WO-A-97 / 29735, and US-A-5989529, all of which disclose sunscreen compositions. However, prior art compositions often feel tacky when applied and can be difficult to achieve uniform application of sunscreen active species.

[0007] This time, unexpectedly, a composition comprising at least one quaternary ammonium agent and a sunscreen active species provided a smooth, uniform application of the sunscreen active species, albeit with low levels of associated drawbacks. We have found that we can provide. In addition, the compositions of the present invention may contain high levels of skin benefit agents that provide superior benefits such as skin feel, skin softness and skin smoothness, while still being greasy, sticky or Defects such as stickiness are low level.

Without wishing to be bound by theory, the quaternary ammonium materials of the present invention are capable of vesicle-forming sunscreen active species and depositing them on the skin, thereby commonly associated with such compositions. There is no stickiness / stickiness, and it is considered that it is surely applied more evenly on the skin. Furthermore, it is believed that the quaternary ammonium agents of the present invention are able to vesicle any moisturizers and deposit them on the skin. This results in a smooth and even application of the moisturizer on the skin with minimal stickiness / greasiness. In addition, the quaternary ammonium substance is more uniformly applied to the skin by the emollient, and the greasiness / greasiness / active substance is used as a light-shielding agent and / or a moisturizer from the skin due to environmental factors such as water or exfoliation. / Helps reduce loss of emollients. Furthermore, it is believed that the quaternary ammonium agent itself provides skin care benefits such as excellent moisturizing properties, excellent skin feel, and excellent skin flexibility.

[0009]   [Outline of the Invention]   According to the invention, (a) at least one quaternary ammonium agent, (B) at least one sunscreen active species A cosmetic composition comprising is provided.

The compositions of the present invention provide a sunburn benefit with low stickiness or tackiness. Moreover, the compositions of the present invention can provide excellent skin care benefits with low levels of defects such as greasiness, tackiness or stickiness.

DETAILED DESCRIPTION OF THE INVENTION The composition of the present invention comprises at least one quaternary ammonium agent and at least one quaternary ammonium agent.
Comprising two sunscreen active species. These elements will be described in further detail below.

The composition can be used for any suitable purpose. In particular, the composition is suitable for topical application to the skin. In particular, the skin care composition may be in the form of creams, lotions, gels and the like. Preferably, the cosmetic composition herein is in the form of an oil-in-water emulsion in which one or more oil phases are present in the water continuous phase, each oil phase being in a miscible or homogeneous form with a single oily component. Or containing a mixture of oily components, the different oil phases containing different substances or combinations of substances from one another.

The composition of the invention preferably comprises vesicles. Preferably,
The vesicles include a quaternary ammonium compound with a sunscreen active species.

Preferably, the composition of the invention is less than 10% by weight, preferably less than 5% by weight,
More preferably it comprises less than 3% by weight, even more preferably 0% by weight of anionic surfactant.

The composition of the present invention is preferably at least about 1,000 mPa · s, preferably in the range of about 1,000 to about 300,000 mPa · s, more preferably about 2,
Within the range of 500 to about 250,000 mPa · s, especially about 5,000 to about 200.
Product viscosity in the range of 2,000 mPas (26.8 ° C, neat, Brookf
field DV-II + Spindle CP52 / CP41).

Quaternary Ammonium Agent The composition of the present invention must contain at least one quaternary ammonium agent. Any quaternary ammonium agent suitable for use in cosmetic compositions may be used in the present invention. The term "quaternary ammonium agent" as used herein refers to a compound or mixture of compounds having 6 or more carbon atoms and having quaternary nitrogen atoms substituted with 1 or more, preferably 2 moieties. Preferably, the quaternary ammonium agent used herein is selected from those having a quaternary nitrogen in which each moiety is substituted with two moieties containing 10 or more, preferably 12 or more carbon atoms. Highly preferred quaternary ammonium agents used herein are those capable of forming vesicles in polar solvents as detected by microscopic analysis (polarization microscopy at × 60 magnification using a Nikon Eclipse E800 microscope). Selected from. As used herein, the term "vesicle" refers to 1 arranged in a closed, usually spherical geometry.
The above bilayer means the bilayer contains a quaternary ammonium agent as described below.

Preferably, the composition comprises at least 0.01% by weight, more preferably at least 0.1% by weight, even more preferably at least 1% by weight, even more preferably at least 3% by weight of a quaternary ammonium agent. Comprises.

[0018]   Preferably, the quaternary ammonium agent used herein is selected from:

[0019]   (A) The following general formula (I):

[Chemical 3] (In the formula, R ₁ and R ₂ are each a C ₁ -C ₄ alkyl or C ₁ -C ₄ hydroxyalkyl group, or hydrogen. R ₃ and R ₄ are each about 8 to about 22 carbon atoms. an alkyl or alkenyl group having .X ^- are quaternary ammonium compounds according to the quaternary ammonium compound and a salt-forming anion other additive components compatible).

[0020]   Preferred quaternary ammonium compounds of this type have the general formula (I) ₁ And R₂Is methyl or hydroxyethyl, R₃And R_FourIs less
A straight chain having 11 atoms, preferably at least 15 carbon atoms or
A quaternary amine having a branched alkyl or alkenyl chain).

[0021]   (B) The following general formula (II) or (III):

[Chemical 4] (In the formula, each R_FiveUnits are independently hydrogen, branched or linear C₁-C₆Archi
Le, branched or straight chain C₁-C₆Hydroxyalkyl and mixtures thereof, preferred
Selected from methyl and hydroxyethyl, each R₆The unit is independent
A linear or branched C₁₁-C_{twenty two}Alkyl, straight chain or branched C₁₁-C _{twenty two} Alkenyl, and mixtures thereof, wherein X is^-Is a skin care active and
It is an anion compatible with the additive component, m is 1 to 4, preferably 2, and n is
Is 1 to 4, preferably 2, and Q is the following:

[Chemical 5] (Wherein R ₇ is a carbonyl unit selected from hydrogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ hydroxyalkyl, and mixtures thereof).

In the above examples of quaternary ammonium compounds, unit-QR ₆ typically includes a fatty acid acyl unit derived from a triglyceride source. The triglyceride source is preferably tallow, partially hydrogenated tallow, lard, partially hydrogenated lard, canola oil, safflower oil, peanut oil, rapeseed oil, sunflower oil, corn oil, soybean oil, Obtained from vegetable oils such as tall oil, rice bran oil and the like and / or partially hydrogenated vegetable oils, and mixtures of these oils.

The counterion X ⁻ in the above compound is any compatible anion, preferably a strong acid (eg chloride, bromide, methyl sulfate, ethyl sulfate, sulfate, nitrate etc.), more preferably chloride or It can be the anion of methyl sulfate. The anion can also, but less preferably, may have a double charge (in this case, X ^- represents a half of the group).

Preferred quaternary ammonium compounds of the present invention are diester and / or diamide quaternary ammonium (DEQA) compounds, said diester and diamide having the general formula (II) (wherein the carbonyl group Q is:

[Chemical 6] Selected from).

Tallow, canola oil and palm oil are convenient and inexpensive sources of fatty acid acyl units suitable for use in the present invention as R ₆ units.

The counterion X ⁻ can be chloride, bromide, methyl sulfate, formate, sulfate, nitrate, and mixtures thereof. In fact, the anion X exists only as a counterion for the positively charged quaternary ammonium compound. The scope of the invention is not considered to be limited to any particular anion.

As used herein, when describing a diester, it will contain the monoesters and triesters normally present as a result of the manufacturing process.

[0028]   (C) The following general formula (IV) or (V):

[Chemical 7] Wherein R ₉ is an acyclic aliphatic C ₁₅ -C ₂₁ hydrocarbon group and R ₁₀ is a C ₁ -C ₆ alkyl or alkylene group.

These ammonium compounds, which have a pKa value of at most about 4, can generate cationic charges in situ when dispersed in aqueous solution, provided that the pH of the final composition is at most about 6. it can.

[0030]   (D) The following general formula (VI) or (VII):

[Chemical 8] Wherein R ₉ and R ₁₀ are as described above and R ₁₁ is selected from C ₁ -C ₄ alkyl and hydroxyalkyl groups.

The counterion X ⁻ can be chloride, bromide, methyl sulfate, formate, sulfate, nitrate, and mixtures thereof. In fact, the anion X simply exists as a counterion for the positively charged quaternary ammonium compound. The scope of the invention is not considered to be limited to any particular anion.

[0032]   (E) The following general formula (VIII) or (IX):

[Chemical 9] (In the formula, n is 1 to 6, R ₉ is selected from acyclic aliphatic C ₁₅ -C ₂₁ hydrocarbon groups, and R ₁₂ is selected from C ₁ -C ₄ alkyl and hydroxyalkyl groups. Quaternary ammonium compound according to

These ammonium compounds (VIII), which have a pKa value of at most about 4, produce a cationic charge in situ when dispersed in an aqueous solution, provided that the pH of the final composition is at most about 6. can do.

The counterion X ⁻ (IX) can be chloride, bromide, methyl sulfate, formate, sulfate, nitrate, and mixtures thereof. In fact, the anion X exists only as a counterion for the positively charged quaternary ammonium compound. The scope of the invention is not considered to be limited to any particular anion.

[0035]   (F) General formula (X), (XI), (XII) or (XIII) shown below:

[Chemical 10]

[Chemical 11] Where R ₅ , R ₆ , Q, n and X ⁻ are as defined above for general formulas (II) and (III) and R ₁₃ is a C ₁ -C ₆ alkylene group, preferably A quaternary ammonium compound selected from an ethylene group and z is 0-4).

[0036]   (G) A mixture of the above quaternary ammonium compounds.

Preferred quaternary ammonium agents for use in the present invention are those described in (b) above. Particularly preferred are diester and / or diamide quaternary ammonium (DEQA) compounds according to the general formula (II) above. Preferred diesters for use herein are of general formula (II), wherein R ₅ , R ₆ and X ⁻ are as defined above, and Q is

[Chemical 12] It is to follow).

Preferred diamides for use herein have the general formula (II), wherein R ₅ , R ₆ and X ⁻ are as defined above, and Q is

[Chemical 13] It is to follow).

Preferred examples of quaternary ammonium compounds suitable for use in the compositions of the present invention are N, N-di (canolyl-oxy-ethyl) -N, N-dimethylammonium chloride, N, N-di (Canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methyl sulfate, N, N-di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) Ammonium chloride and mixtures thereof. Particularly preferred for use herein is N, N
-Di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methylsulfate.

While quaternary ammonium compounds derived from “canolyl” fatty acid acyl groups are preferred, other suitable examples of quaternary ammonium compounds include the term “canolyl” in the above examples,
It is derived from the fatty acid acyl group replaced by the term "tallowyl, cocoyl, palmyl, lauryl, oleyl, ricinoleyl, stearyl, palmityl" corresponding to the triglyceride source from which the fatty acid acyl unit is derived. These alternative fatty acid acyl sources may comprise fully saturated, or preferably at least partially unsaturated chains.

Sunscreen The second essential element of the compositions of the present invention is that they contain at least one sunscreen active species. These sunscreen active species include both organic compounds and their salts, as well as inorganic particulate materials. Without wishing to be bound by theory, it is believed that sunscreen agents protect from UV radiation by one or more of the following mechanisms, including absorption, scattering and reflection of UV radiation.
Non-limiting examples of these sunscreen agents are US Patent No. 5,087,445 issued to Haffey et al. On February 11, 1992 and US Patent No. No. 5,073,372, Turn, December 17, 1991
US Pat. No. 5,073,371, issued Nov. 3, 1992 to Sa.
U.S. Pat. No. 5,160,731 issued to Batelli et al., August 1992 11
U.S. Pat. No. 5,138,089, issued to Sabatelli et al., Dated 8 August 1991.
U.S. Patent Nos. 5,041,282, 1991, issued to Sabatelli on March 20, 1991
U.S. Pat. No. 4,999,186, issued to Sabatelli et al. On March 12, 1
U.S. Pat. No. 4,937,370 issued June 26, 990 to Sabatelli and Segarin et al., Cosmetics Science and Technology, Cosmetics Science and Technology, Chapter VIII, p. 189 et seq. Among the sunscreen agents, 2-ethylhexyl p-methoxycinnamate, octyl salicylate, octocrylene, oxybenzone, 2-ethylhexyl N, N-dimethylaminobenzoate, p-aminobenzoic acid, 2-phenyl-benzimidazole- are preferred. 5-
Sulfonic acid, homomenthyl salicylate, DEA p-methoxycinnamate, 4,4'methoxy-t-butyldibenzoylmethane, 4-isopropyldibenzoylmethane, 3- (4-methylbenzylidene) camphor, 3-benzylidene camphor, 2, 4-N, N-dimethylaminobenzoic acid ester with 4-dihydroxybenzophenone, 2
4-N, N with -hydroxy-4- (2-hydroxyethoxy) benzophenone
-Dimethylaminobenzoic acid ester, 4-N, N-dimethylaminobenzoic acid ester with 4-hydroxydibenzizoyl-methane, 4-N, N-dimethyl with 4- (2-hydroxyetheroxy) dibenzoylmethane Aminobenzoic acid ester, 4-N, N-di (2-ethylhexyl) -aminobenzoic acid ester with 2,4-dihydroxybenzophenone, 4-N, with 2-hydroxy-4- (2-hydroxyethoxy) benzophenone N-di (2-ethylhexyl) aminobenzoic acid ester, 4-hydroxydibenzoylmethane with 4-N, N-di (2-ethylhexyl) aminobenzoic acid ester, 4- (2-hydroxyethoxy) dibenzoylmethane 4-N, N-di (2-ethylhexyl) aminobenzoic acid ester, 2,4-dihydro 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with cibenzophenone, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 2-hydroxy-4- (2-hydroxyethoxy) benzophenone Acid ester, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 4-hydroxydibenzoylmethane, 4-N, N- (2- with 2- (2-hydroxyethoxy) dibenzoylmethane Ethylhexyl) methylaminobenzoic acid ester, titanium dioxide, zinc oxide, iron oxide, and mixtures thereof.

More preferred for use in the compositions described herein is N, N-dimethyl-p.
-2-ethylhexyl aminobenzoate, 2-ethylhexyl p-methoxycinnamate, octocrylene, octyl salicylate, homomenthyl salicylate, p-aminobenzoic acid, oxybenzone, 2-phenylbenzimidazole-5-sulfonic acid, p-methoxycinnamic acid DEA , 4,4'-methoxy-t-butyldibenzoylmethane, 4-isopropyldibenzoylmethane, 3- (4-methylbenzylidene)
Camphor, 3-benzylidene camphor, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 4- (2-hydroxyethoxy) dibenzoylmethane,
A sunscreen agent selected from titanium dioxide, zinc oxide, iron oxide, and mixtures thereof.

The exact amount of sunscreen that can be used will vary depending on the sunscreen selected and the desired sunscreen factor (SPF) to be achieved. SPF
Is a standard measure of photoprotection of sunscreen agents against erythema. Federal Register 4
Vol. 3, No. 166, pp. 38206-38269 (August 25, 1978). However, preferably the compositions of the present invention contain 0.01 to 20% by weight, more preferably 0.1 to 10% by weight of sunscreen active species.

Optional Ingredients The compositions herein are suitable for making the compositions more cosmetically or aesthetically acceptable, or for providing additional use benefits,
Various optional ingredients can be included. Such conventional optional ingredients are familiar to those skilled in the art. These include the CTFA International Cosmetic Ingredient Dictionary and Guide, 7th Edition, edited by Wenninger and McEwen (The Cosmetic, Toiletry, and Fragranc
e Association, Inc., Washington, DC, 1997). Some non-limiting examples of these optional ingredients are listed below.

Skin Benefit Agents It is highly preferred that the compositions of the present invention include a skin benefit agent. The term "skin benefit agent" as used herein means any compound or mixture of compounds that provides benefits to the skin, such as moisturizing, protection, skin feel, skin softness and / or skin smoothness. To do. Preferred skin benefit agents for use herein are moisturizers, emollients and mixtures thereof. Preferably, the composition of the present invention contains a moisturizer and an emollient.

Preferably, the compositions of the present invention contain at least 1% by weight of skin benefit agent. More preferably, the composition is 2-70% by weight, preferably 5-60% by weight,
More preferably it contains 10-55% by weight of skin benefit agent.

Humectants A highly preferred optional ingredient of the compositions of the present invention is a humectant. As used herein, the term "humectant" means a substance that provides the skin with water retention benefits. Preferably, the composition of the invention is at least 1% by weight, more preferably at least 5%.
%, More preferably at least 10% and even more preferably at least 20% by weight of humectant.

Any humectant suitable for use in the cosmetic composition may be used here. Non-limiting examples of moisturizers suitable for use in the present invention are WO 98/22085, W
O98 / 18444 and WO 97/01326. Preferably, the humectants used herein are amino acids and their derivatives such as proline and arginine aspartate, 1,3-butylene glycol, propylene glycol and water and codium tomentosum extract, collagen amino acids or Peptide, creatinine, diglycerol, biosaccharide gum-1, glucamine salt, glucuronate, glutamate, polyethylene glycol ether of glycerin (for example, glyceres 20), glycerin, glycerol monopropoxylate, glycogen, hexylene glycol, honey,
And their extracts or derivatives, hydrogenated starch hydrolysates, hydrolyzed mucopolysaccharides, inositols, keratin amino acids, ureas, LAREX A-200 (
Available from Larex), glycosaminoglycan, methoxy PEG10, methylglucet-10 and -20 (both are commercially available from Amerchol in Edison, NJ), methyl glucose, 3-methyl-1,3-butanediol. , N-acetylglucosamine salts, polyethylene glycol and their derivatives (PEG1
5 butanediol, PEG4, PEG5 pentaerythritol, PEG6, PEG
8, such as PEG9), pentaerythritol, 1,2-pentanediol, P
PG-1 glyceryl ether, PPG-9, 2-pyrrolidone-5-carboxylic acid and its salts (such as glyceryl pca), saccharide isomerate, SEAC
AREs (available from Secma), sericin, silk amino acids, sodium acetyl hyaluronate, sodium hyaluronate, sodium polyaspartate, sodium polyglutamate, sorbet 20, sorbet 6; sugars and sugars such as glucose, mannose and polyglycerol sorbitol. It is selected from, but not limited to, alcohols and their derivatives, trehalose, triglycerol, trimethiolpropane, tris (hydroxymethyl) aminomethane salts, and yeast extracts, and mixtures thereof.

More preferably, humectants for use herein are selected from glycerin, urea, butylene glycol, polyethylene glycol and their derivatives, or mixtures thereof. More preferably, the humectant for use herein is selected from glycerin, urea and mixtures thereof, especially glycerin.

Emollients Another highly preferred optional ingredient of the compositions of the present invention is emollients. Emollients tend to make the skin smooth, increase the smoothness and suppleness of the skin, prevent or soften the skin and / or protect it. A wide range of suitable emollients are known and can be used herein. Sagarin, Cosme
Tics, Science and Technology, Second Edition, Volume 1, pp. 32-43 (1972), gives numerous examples of substances suitable for use as emollients. Preferably, the composition of the invention is greater than 1% by weight, more preferably at least 5% by weight.
, More preferably at least 10% by weight of emollient.

[0051]   Preferably, the emollient used herein is selected from:

I) about dodecane, squalane, petrolatum, cholesterol and their derivatives, hydrogenated polyisobutylene, isohexadecane and C ₇ -C ₄₀ isoparaffins, which are C ₇ -C ₄₀ branched chain hydrocarbons. A straight or branched chain hydrocarbon having from 7 to about 40 carbon atoms.

[0053] ii) C ₁ -C ₃₀ carboxylic acids and C ₂ -C ₃₀ C ₁ -C ₃₀ alcohol esters of dicarboxylic acids (e.g., isononyl isononanoate, isopropyl myristate,
Myristyl propionate, isopropyl stearate, behenyl behenate, dioctyl maleate, diisopropyl adipate and diisopropyl dilinoleate).

Iii) Mono-, di- and triglycerides of C ₁ -C ₃₀ carboxylic acids, and their ethoxylated derivatives. Suitable polyethylene glycol derivatives of glycerides include PEG-20 almond glyceride, PEG-60 almond glyceride, PEG-11 avocado glyceride, PEG-6 caprin / capryl glyceride, PEG-8 caprin / capryl glyceride, PEG-20 corn glyceride, PEG-60 corn glyceride, PEG-60 evening primrose glyceride, PEG-7 glyceryl cocoate, PEG-30 glyceryl cocoate,
PEG-40 glyceryl cocoate, PEG-78 glyceryl cocoate, PE
G-80 glyceryl cocoate, PEG-12 glyceryl dioleate, PEG
-15 glyceryl isostearate, PEG-20 glyceryl isostearate, PEG-30 glyceryl isostearate, PEG-75 cocoa butter glyceride, PEG-20 hydrogenated palm oil glyceride, PEG-70 mango glyceride,
PEG-13 mink glyceride, PEG-75 shorea butter glyceride, PEG-10 olive glyceride, PEG-12 palm kernel glyceride, P
EG-45 palm kernel glyceride, PEG-8 glyceryl laurate and PEG
-30 glyceryl laurate is mentioned. Mixtures of polyethylene glycol derivatives of glycerides can also be used here.

[0055]   iv) C₁-C₃₀Alkylene glycol esters of carboxylic acids (eg C₁-C ₃₀ Ethylene glycol mono and diesters of carboxylic acids, and propylene
Glycol mono and diesters such as ethylene glycol distearate)
.

V) Organopolysiloxane oil. The organopolysiloxane oil may be volatile, non-volatile or a mixture of volatile and non-volatile silicones. The term “non-volatile” as used in this context refers to silicones that are liquid under ambient conditions and have a flash point above about 100 ° C. (under 1 atmosphere). The term "volatile" as used in this context refers to all other silicone oils. Suitable organopolysiloxanes are selected from a wide range of silicones with a wide range of volatility and viscosities. Nonvolatile polysiloxanes are preferred. Suitable silicones are disclosed in US Pat. No. 5,069,897 issued Dec. 3, 1991. Preferred for use herein are organopolysiloxanes selected from polyalkyl siloxanes, alkyl substituted dimethicones, dimethiconols, polyalkylaryl siloxanes and mixtures thereof. More preferred for use herein are polyalkyl siloxanes and cyclomethicones. Preferred among the polyalkylsiloxanes is dimethicone.

Vi) Vegetable oils and hydrogenated vegetable oils. Examples of vegetable oils and hydrogenated vegetable oils are safflower oil, castor oil, coconut oil, cottonseed oil, menhaden oil, palm kernel oil, palm oil, peanut oil, soybean oil, rapeseed oil, linseed oil, rice bran oil, pine oil, sesame oil. , Sunflower seed oil, partially and fully hydrogenated oils from the aforementioned sources and mixtures thereof.

Vii) Animal fats and oils (eg cod liver oil, lanolin, and their derivatives such as acetylated lanolin and isopropyllanolate). Lanolin oil is preferred.

Viii) C ₄ -C ₂₀ alkyl ethers of polypropylene glycol, C ₁ -C ₂₀ carboxylic acid esters of polypropylene glycol, and di C ₈ -C ₃₀ alkyl ethers are also useful, examples of which are: , PPG-14 butyl ether, PPG-15 stearyl ether, dioctyl ether, dodecyl octyl ether, and mixtures thereof.

[0060]   ix) Polyol carboxylic acid ester.

[0061]   x) A mixture of the above.

Emollients preferred for use in the compositions herein include dodecane, squalane, cholesterol and their derivatives, isohexadecane, isononyl isononanoate, petrolatum, lanolin and their derivatives, safflower oil, castor oil. , Palm oil, cottonseed oil, palm kernel oil, palm oil, peanut oil, soybean oil, polyol carboxylic acid esters and mixtures thereof. Emollients preferred for use herein are selected from polyol carboxylic acid esters, petrolatum and mixtures thereof.

These esters are derived from a sugar or polyol moiety and one or more carboxylic acid moieties. Depending on the constituent acids and sugars, these esters may be present in liquid or solid form at room temperature. Examples of liquid esters are glucose tetraoleate, soybean oil fatty acid (unsaturated) glucose tetraester, mixed soybean fatty acid mannose tetraester, oleic acid galactose tetraester, linoleic acid arabinose tetrasether, xylose tetralino. Rate, galactose pentaoleate, sorbitol tetraoleate, sorbitol hexaester of unsaturated soybean oil fatty acid, xylitol pentaoleate, sucrose tetraoleate, sucrose pentaoleate, sucrose hexaoleate, sucrose hepatate, sucrose octaoleate And mixtures thereof. Examples of solid esters include a carboxylic acid ester moiety of 1
Palmitolate and arachidate sorbitol hexaester in a molar ratio of 2: 2, linoleate in a carboxylic acid ester moiety in a 1: 3 molar ratio and raffinose octaester in a behenate, and esterified carboxylic acid moiety in a 3: 4 molar ratio. Sunflower seed oil fatty acid and lignocerate maltose heptaester, esterified carboxylic acid moiety in a 2: 6 molar ratio of oleate to behenate sucrose octaester and esterified carboxylic acid moiety in a 1: 3: 4 molar ratio. There is a ratio of laurate and linoleate to the behenate sucrose octaester. Preferred solid materials have a degree of esterification of 7-8 and a fatty acid moiety of 1
Sucrose polyester which is C18 mono- and / or di-unsaturated fatty acid and behenic acid in a molar ratio of unsaturated fatty acid: behenic acid of 7 to 3: 5. A particularly preferred solid sugar polyester is an octaester of sucrose with about 7 behenic acid fatty acid moieties and about 1 oleic acid moiety in the molecule. Other substances include cottonseed oil of sucrose or fatty acid esters of soybean oil. The ester material is also
U.S. Pat. No. 2,831,854, U.S. Pat. No. 4,005,196, issued Jan. 25, 1977 to Jandacek, U.S. Pat. No. 4,005 issued Jan. 25, 1977 to Jandacek. , 195, US Pat. No. 5,306,516 issued to Letton et al. On April 26, 1994, US Pat. No. 5,306,515 issued to Letton et al. On April 26, 1994, US Pat. No. 5,305,514, issued to Letton et al. On April 26, 1994, Jandacek on January 10, 1989.
U.S. Pat. No. 4,797,300 issued Jun. 15, 1976 to Rizz
US Pat. No. 3,963,699 issued to i et al., Vol.
U.S. Pat. No. 4,518,772 issued to penhein and U.S. Pat. No. 4,517,360 issued to Volpenhein on May 21, 1985.

Polyol fatty acid polyesters suitable for use herein can be prepared by a variety of methods familiar to those skilled in the art. These methods include transesterification of polyols with methyl, ethyl or glycerol fatty acid esters using various catalysts, acylation of polyols with chlorides of fatty acids, acylation of polyols with fatty acid anhydrides, with fatty acids themselves. Examples include acylation of polyols. For example, 19
See U.S. Pat. No. 2,831,854, U.S. Pat. No. 4,005,196 issued Jan. 25, 1977 to Jandacek.

A particularly preferred material is known by the INCI name Sucrose Polycotton Sidate.

Other Skin Benefit Agents Other skin benefit agents may be useful in the compositions of the present invention. Examples of other skin benefit agents that may be used in the composition include:

(A) Vitamin Compound The present composition may contain a vitamin compound, a precursor, and a derivative thereof. These vitamin compounds may be in natural or synthetic form. Suitable vitamin compounds include vitamin A (eg, beta-carotene, retinoic acid, retinol, retinoid, retinyl palmitate, retinyl propionate, etc.), vitamin B (eg, niacin, niacinamide, riboflavin, pantothenic acid, etc.). ), Vitamin C (eg, ascorbic acid), vitamin D (eg, ergosterol, ergocalciphenol, cholecalciferol, etc.), vitamin E (eg, tocopherol acetate, etc.), and vitamin K (eg, phytonadione, menadione, etc.). Compounds such as futhiocol). Preferred vitamin compounds for use definitive composition of the present invention is a vitamin B ₃ compound. Vitamin B ₃ compounds, as described in WO-A-97/39733, which is particularly useful for regulating skin condition. When present, the composition of the present invention is preferably from about 0.01 to about 50% by weight, more preferably from about 0.1 to about 10% by weight, even more preferably from about 0.5 to about 5% by weight. Contains vitamin B ₃ compounds of

As used herein, a “vitamin B ₃ compound” has the formula:

[Chemical 14] Wherein R is —CONH ₂ (ie, niaciamido), —COOH (ie, nicotinic acid) or —CH ₂ OH (ie, nicotinyl alcohol), a derivative thereof, and any of the foregoing. Means salt.

Representative derivatives of the aforementioned vitamin B ₃ compounds include nicotinic acid esters including non-vasodilators of nicotinic acid, nicotinyl amino acids, nicotinyl alcohol esters of carboxylic acids, nicotinic acid N-oxide and niacin. De N-
An oxide is mentioned.

Examples of suitable vitamin B ₃ compounds are well known in the art and are available from numerous vendors (eg, Sigma Chemical Company (St. Louis, MO), ICN Biomedicals, I.
nc. (Irvin, CA) and Aldrich Chemical Company (Milwaukee, WI).

The vitamin compound may be contained as a substantially pure material or as an extract obtained by suitable physical and / or chemical separation from natural (eg plant) sources.

(B) Anti-wrinkle and anti-skin atrophy active substance Examples of the anti-wrinkle and anti-skin atrophy active substance which may be used in the composition of the present invention include lactic acid and derivatives thereof, retinoic acid and derivatives thereof ( For example, cis and trans), retinol, retinyl ester, niacinamide, salicylic acid and their derivatives, sulfur-containing D and L amino acids and their derivatives and salts (particularly N-acetyl derivatives, preferred examples of which are N-acetyl). -L-cysteine), thiols (e.g. ethanethiol), hydroxy acids, phytic acid, lipoic acid, lysophosphatidic acid, and skin exfoliating agents (e.g. phenol and the like), but are not limited thereto.

(C) Antibacterial and Antifungal Actives Examples of antibacterial and antifungal actives that may be used in the compositions of the present invention include β-lactam drugs, quinolone drugs, ciprofloxacin, norfloxacin, tetracycline. , Erythromycin, amikacin, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 3,4,4'-trichlorocarbanilide, phenoxyethanol, phenoxypropanol, phenoxyisopropanol, doxycycline, capreomycin, chlorhexidine, chlorotetracycline, oxy. Tetracycline, clindamycin, ethambutol, hexamidine isethionate, metronidazole, pentamidine, gentamicin, kanamycin, lineeomycin, metacycline, metena Min, minocycline, neomycin, netilmycin, paromomycin, streptomycin, tobramycin, miconazole, tetracycline hydrochloride, erythromycin, zinc erythromycin, erythromycin estrate, erythromycin stearate, amikacin sulfate, doxycycline hydrochloride, capreomycin sulfate, chlorohexidine gluconate, chlorhexidine hydrochloride. , Chlorotetracycline hydrochloride, oxytetracycline hydrochloride, clindamycin hydrochloride, ethambutol hydrochloride,
Metronidazole hydrochloride, pentamidine hydrochloride, gentamicin sulfate, kanamycin sulfate, lineeomycin hydrochloride, metacycline hydrochloride, methenamine hippurate, methenamine mandelate, minocycline hydrochloride, neomycin sulfate, netilmycin sulfate, paramomycin sulfate, streptomycin sulfate, tobramycin sulfate, miconazole hydrochloride, Examples include, but are not limited to, amanfazine hydrochloride, amanfazine sulfate, octopirox, parachlorometaxylenol, nystatin, tolnaftate, zinc pyrithione and clotrimazole.

Polar Solvent The composition of the present invention may also contain a polar solvent. Any polar solvent suitable for use in cosmetic compositions may also be used here. However, the polar solvent must be sufficiently polar to form vesicles in the present invention. Preferably, the polar solvent used in the composition of the present invention is water.

Preferably, the composition will contain 10 to 90% by weight, more preferably 20 to 80% by weight and even more preferably 30 to 60% by weight of polar solvent.

Thickener The composition of the present invention preferably contains a thickener. Any thickening agent suitable for use in cosmetic compositions may also be used here. Preferred thickeners are selected from nonionic water soluble polymers, fatty alcohols and mixtures thereof. Suitable nonionic polymers include cellulose ethers (eg, hydroxybutylmethylcellulose, hydroxypropylcellulose, hydroxylpropylmethylcellulose, ethylhydroxyethylcellulose, hydrophobically modified hydroxyethylcellulose and hydroxyethylcellulose), poly (ethylene oxide), polyvinyl alcohol. , Polyvinylpyrrolidone, hydroxypropyl guar gum, amulose, hydroxyethylamylose, starch, and water-soluble polymers such as starch derivatives. Suitable fatty alcohols represented by the following general formula: RCH2OH (wherein, R is C _8-20 alkyl) is a non-volatile primary alcohols high molecular weight with. They are fatty acids COOH
It can be produced from natural fats or oils by reducing the groups to hydroxy functional groups. Alternatively, fatty alcohols of the same or similar structure can be prepared according to conventional synthetic methods known in the art. Suitable fatty alcohols, behenyl alcohol, C ₉ -C ₁₁ alcohols, C ₁₂ -C ₁₃ alcohols, C _{1 2} -C ₁₅ alcohols, C ₁₂ -C ₁₆ alcohols, C ₁₄ -C ₁₅ alcohol, capryl alcohol, cetearyl Alcohol, coconut alcohol, decyl alcohol,
Examples include, but are not limited to, isocetyl alcohol, isostearyl alcohol, lauryl alcohol, oleyl alcohol, palm kernel alcohol, stearyl alcohol, cetyl alcohol, tallow alcohol, tridecyl alcohol or myristyl alcohol.

Other Optional Ingredients The compositions of the present invention can contain a wide range of other optional compositions. These additional ingredients should be pharmaceutically acceptable. Examples of non-limiting functional types of ingredients suitable for use in the compositions of the present invention include skin exfoliants, absorbents, anti-acne actives, anti-caking agents, anti-dandruff agents, Antiperspirant,
Antioxidants, antiviral actives, artificial tanning actives and promoters, biological additives, bleaches, bleach activators, brighteners, builders, buffers, chelating agents, chemical additives, colorants, Cosmetics, cleansers, cosmetic astringents, cosmetic biocides, denaturants, deodorants, desquamation active substances, depilatory agents, pharmaceutical astringents, pigments, dye transfer agents, enzymes, external painkillers, foaming agents, flavors , Film-forming agents, fragrance components, insecticides, fungicides, non-steroidal anti-inflammatory active substances, opacifiers, oxidative pigments, oxidizing agents, pest control components, pH regulators such as citric acid, pH buffering Liquid, pharmaceutically active substance,
Softeners, preservatives, radical scavengers, skin, hair or nail bleach, skin,
Hair or nail conditioners, skin, hair or nail solubility enhancers, stabilizers, surfactants, surface conditioners, reducing agents, temperature suppressants, viscosity modifiers, and heat retention agents such as exothermic zeolites. To be Aesthetic ingredients such as coloring, fragrance oils, and skin healing agents are also useful herein. Other optional ingredients herein include pigments. Suitable pigments for use in the compositions of the present invention can be organic and / or inorganic. Also included within the term "pigment" are matte finishes and materials with low color and luster such as light scattering agents. Examples of suitable pigments are iron oxide, aciglutamate iron oxide, titanium dioxide, ultramarine blue, D & C dye,
Carmine, and mixtures thereof.

Formulation Process Preferably, the compositions of the present invention may be prepared in such a manner that the quaternary ammonium compound forms vesicles. The vesicles also preferably contain a humectant. Preferably, the vesicles also contain an emollient. More preferably, the vesicles contain sunscreen active species. To ensure optimum performance, the composition of the present invention comprises: (i) all or part of the quaternary ammonium agent, a humectant, a water-soluble sunscreen active at a temperature above the melting point of the quaternary ammonium agent. Seed, water-soluble skin care active species (if included), and preferably a polar solvent, (ii) optionally shaking the mixture vigorously, (iii) in a separate container, the emulsion below: (An oil phase containing an emollient, a suitable thickener (if the thickener is oil soluble), an oil soluble sunscreen active species and any remaining quaternary ammonium agent, The water phase is prepared separately and water, a suitable thickening agent (if the thickening agent is water soluble) and the remaining water soluble components are combined in the oil phase. Heated to the same temperature as above.) (Iv) Next, emulsion The temperatures of the oil phase and the water phase are made substantially equal, and the water phase and the oil phase are shaken and combined, and (v) in the production of the emulsion, the above-mentioned milk is shaken while shaking the mixture produced in the step (i). It is preferably prepared so as to be added to a suspension.

Method of Use The cosmetic composition of the present invention may be used in the conventional manner for treating skin. An effective amount of the composition is typically about 0.1 to about 50 grams, preferably about 1 to about 20.
Applied to moist or dry, preferably moist skin, in grams. Application of the composition typically involves rubbing the composition onto the skin, generally with the hands and fingers. The composition is then left on the skin, or preferably the skin is rinsed.

[0080]   Therefore, the preferred method of treating the skin is as follows:   (A) applying an effective amount of a cosmetic composition to the skin,   (B) The process of rinsing the skin Comprises.

A preferred embodiment of the present invention comprises the above method involving application of the composition on dry skin prior to application on moist skin. Therefore, the preferred method is:
(I) applying an effective amount of the cosmetic composition to dry skin; (ii) rinsing the skin with a shower; (iii) further applying the composition; and (iv) further rinsing. It consists of

Much of the damage to human skin is caused by repeated exposure to compositions containing surfactants during the cleaning routine. It has been found that the composition of the present invention can be used to reduce this damage. Thus, another preferred method is: (i) washing the skin with a surfactant-containing composition, (ii) rinsing the skin, (iii) applying the composition of the invention to moist skin. (Iv) rinsing the skin.

The compositions of the present invention have also been found to be particularly useful when incorporated as part of normal routine. Accordingly, another preferred method is: (i) applying to the skin a composition containing (a) at least one quaternary ammonium compound and (b) a humectant; (ii) rinsing the skin. (Iii) repeating steps (i) and (ii) within 48 hours.

The compositions of the present invention are also caused by damage caused by exposure of the skin to UV irradiation, damage caused by exposure of the skin to water during swimming or similar exercise in water, shaving or exfoliation. It may be useful in reducing the damage caused by, or the damage caused by exposure of the skin to water while bathing.

Examples The following examples further describe preferred embodiments within the scope of the present invention. The examples are for illustration only and are not to be construed as limiting the invention, as many variations of the invention are possible without departing from the spirit or scope of the invention. Unless otherwise noted, all ingredients are listed as weight percent of active ingredient.

[0086]

[Table 1]

[Table 2]

[0087]

[Table 3]

[Table 4]

[0088]

[Table 5]

[Table 6]

[Table 7]

[0089]

[Table 8]

[Table 9] 1; available from Croda 2; available from Floratech, AZ, USA 3; available from Hoffman La Roche, NJ, USA 4; available from Amerchol, NJ, USA 5; available from Rhodia, NJ, USA

Examples 1, 4, 7, 9, 17, 20, 22, 24, 28, 36, 38, 47,
In 49, 53, 56, the quaternary ammonium compound used is distearyl dimethyl ammonium chloride (trade name: Varis) supplied by Goldschmidt.
of TA100). -Examples 2, 3, 5, 6, 8, 10, 15, 16, 18, 19, 21, 23, 2
6, 27, 31, 33, 34, 35, 37, 41, 45, 46, 48, 50, 5
In 1, 52, 54, 55, the quaternary ammonium compound used is Goldschmid.
N, N-di (canoyl-oxy-ethyl) -N-methyl, N- (supplied from t
2-Hydroxyethyl) ammonium methyl sulfate (trade name: Rewoq
uat V3620). The quaternary ammonium compound used in Example 11 was N, N-di (canoyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methyl sulfate (trade name: supplied by Goldschmidt). Rewoquat WE 18). The quaternary ammonium compound used in Example 12 is N, N-di (canoyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium chloride (developed substance: WE25) supplied from Goldschmidt. Is. The quaternary ammonium compound used in Example 13 is methylbis (hydrogenated tallowamidoethyl) (2-hydroxyethyl) ammonium methyl sulfate (trade name: Varisoft 110) supplied by Goldschmidt.
The quaternary ammonium compound used in Example 14 is methylbis (tallowamidoethyl) (2-hydroxyethyl) ammonium methyl sulfate (trade name: Varisoft 222) supplied by Goldschmidt. -In Example 25, the quaternary ammonium compound used is methyl-1-tallow oil ethyl-2-tallow imidazoline (developed substance) supplied from Goldschmidt. -In Example 29, the quaternary ammonium compound used is methyl-1-tallowamidoethyl-2-tallowimidazoline (developed substance) supplied from Goldschmidt. The quaternary ammonium compound used in Example 30 is methyl-1-tallowoylethyl-2-tallowimidazolinium methylsulfate supplied by Goldschmidt. In Example 32, the quaternary ammonium compound used was methyl-1-tallowamidoethyl-2-tallowimidazolinium methylsulfate (trade name: Varisoft 475, Varisoft 445 supplied from Goldschmidt.
). -In Example 39, the quaternary ammonium compound used is N, N-dimethyl-N- (canoyl-oxy-ethyl) -N- (canoramidoethyl) amine supplied by Kao. -In Example 40, the quaternary ammonium compound used is N, N-dimethyl-N- (canoyl-oxy-ethyl) -N- (canoramidoethyl) ammonium methyl sulfate supplied by Kao. -In Example 42, the quaternary ammonium compound used is N, N'-bis (2-taloyloxy), as disclosed by Ciba-Geigy in U.S. Pat. Nos. 4,728,337, 4,721,512 and 4,906,413. Ethyl) -N, N, N ',
It is N'-tetramethylene diammonium dichloride. -In Example 43, the quaternary ammonium compound used is N, N'-bis (2-canoyloxyethyl) -N, as disclosed in Goldchmidt-Witco in EP 0503155 A1 and EP 0803498. N'-dimethyl-N
, N ′-(2-hydroxyethyl) -1,6-hexanediammonium methylsulfate. -In Example 44, the quaternary ammonium compound used is WO98 / by Kao.
49132 and di- and oligoesters prepared by reaction of fatty acids, difunctional (or polyfunctional) acids and triethanolamine followed by quaternisation as disclosed in US Pat. No. 5,880,289 to Henkel. It is the fourth compound.

Regarding Examples Containing Process Component C 1. Premix 1: Combine the ingredients of Group A at a temperature above the transition temperature of the selected quaternary ammonium compound (keep a predetermined proportion of the quaternary ammonium compound and water). Shake this premix vigorously. 2. Premix 2: Combine the remaining quaternary ammonium compound and water not previously used in Premix 1 with the ingredients of Group B and Group C. Heat to a temperature above the melting point of the quaternary ammonium compound and oil. 3. Premixes 1 and 2 are combined, cooled to 40 ° C. and stirred in the perfume ingredients.

Regarding Examples Containing Component D 1. Premix 1: Combine Group A ingredients at a temperature above the transition temperature of the selected quaternary ammonium compound (keep a predetermined proportion of water). Shake the premix vigorously. 2. Premix 2: Water not previously used in Premix 1 and components of Group D are shaken to combine. 3. Combine components of Premixes 1 and 2 and Groups B and E. Shake vigorously.

The compositions of the above examples have a low degree of defects such as greasiness, stickiness or stickiness, excellent moisturizing properties, excellent hydration, excellent skin feel, excellent skin flexibility and / Or provide excellent skin care benefits such as excellent skin smoothness.

─────────────────────────────────────────────────── ─── Continued front page    (31) Priority claim number 60 / 201,798 (32) Priority date May 4, 2000 (May 4, 2000) (33) Priority claiming countries United States (US) (81) Designated countries EP (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, I T, LU, MC, NL, PT, SE), OA (BF, BJ , CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG), AP (GH, GM, K E, LS, MW, MZ, SD, SL, SZ, TZ, UG , ZW), EA (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM), AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, C N, CR, CU, CZ, DE, DK, DM, EE, ES , FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, K R, KZ, LC, LK, LR, LS, LT, LU, LV , MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, S I, SK, SL, TJ, TM, TR, TT, TZ, UA , UG, US, UZ, VN, YU, ZA, ZW (72) Inventors Evans and Erica Lewis             England, Berkshire, Earl Gee             17,0 Edie, Hungerford, Pro             ー, house, court, plow, cottage (72) Inventor Fanose Thayes, Christina Emma               Inge             United Kingdom, Sally, GU21, 4 E             Kusudi, walking, hosel, ho             Sel, Bursh, Lynton (72) Inventor Trani, Marina             British country, Berkshire, SL 5,             9 Dial, South, Ascot, Vi             Kutria, Road 95 F-term (reference) 4C083 AB032 AB102 AB211 AB231                       AB241 AC012 AC072 AC122                       AC211 AC302 AC312 AC341                       AC342 AC471 AC472 AC482                       AC521 AC532 AC542 AC551                       AC581 AC642 AC682 AC691                       AC692 AC791 AD152 AD172                       AD352 AD512 AD531 AD622                       AD662 BB05 BB46 BB51                       CC02 CC19 DD23 EE12 EE17

Claims (10)

[Claims] 1. (a) at least one quaternary ammonium agent;   (B) at least one sunscreen active species, A cosmetic composition comprising. 2. The composition of claim 1, wherein the composition further comprises a skin benefit agent. 3. The composition according to claim 1 or 2, wherein the composition further comprises a skin benefit agent selected from humectants, emollients and mixtures thereof. 4. The sunscreen active species is 2-ethylhexyl N, N-dimethyl-p-aminobenzoate, 2-ethylhexyl p-methoxycinnamate, octocrylene, octyl salicylate, homomenthyl salicylate, p-aminobenzoic acid, Oxybenzone, 2-phenylbenzimidazole-5-sulfonic acid, p-
Methoxycinnamic acid DEA, 4,4′-methoxy-t-butyldibenzoylmethane,
4-isopropyldibenzoylmethane, 3- (4-methylbenzylidene) camphor,
3-benzylidene camphor, selected from 4-N, N- (2-ethylhexyl) methylaminobenzoate ester with 4- (2-hydroxyethoxy) dibenzoylmethane, titanium dioxide, zinc oxide, iron oxide, and mixtures thereof The composition according to any one of claims 1 to 3, which is 5. The composition comprises 0.01 to 20% by weight, more preferably 0.1.
A composition according to any one of claims 1 to 4, comprising 1 to 10% by weight of sunscreen active species. 6. The quaternary ammonium agent is represented by the following general formula (II) or (I
II): Where each R ₅ unit is independently from hydrogen, branched or straight chain C ₁ -C ₆ alkyl, branched or straight chain C ₁ -C ₆ hydroxyalkyl and mixtures thereof, preferably methyl and hydroxyethyl. Selected, each R ₆ unit is independently
Linear or branched C ₁₁ -C ₂₂ alkyl, linear or branched C ₁₁ -C ₂₂ alkenyl, and mixtures thereof, X ⁻ is an anion compatible with the active skin care species and additive ingredients. , M is 1 to 4, preferably 2, and n is 1 to 4,
Preferably 2 and Q is as follows: Wherein R ₇ is a carbonyl unit selected from hydrogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ hydroxyalkyl and mixtures thereof). The composition according to any one of claims 1 to 5. 7. The quaternary ammonium agent is N, N-di (canoyl-oxy-ethyl) -N, N-dimethylammonium chloride, N, N-di (canoyl-).
Oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methyl sulfate, N, N-di (canoyl-oxy-ethyl) -N-methyl, N
7. A composition according to any one of claims 1 to 6 selected from-(2-hydroxyethyl) ammonium chloride and mixtures thereof. 8. The composition of any one of claims 1-7, wherein the composition comprises vesicles, the vesicles containing a quaternary ammonium agent with a sunscreen active species. 9. The composition according to claim 1, wherein the composition comprises less than 5% by weight, preferably less than 3% by weight, preferably 0% by weight of anionic surfactant. object. 10. Use of the composition according to any one of claims 1 to 9 for the treatment of skin.