JP2003183154A5

JP2003183154A5 -

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Publication number: JP2003183154A5
Authority: JP; Japan
Prior art keywords: sodium; heparin; preservative; subjecting; injection
Prior art date: 2001-12-20
Legal status : Granted

Application number

JP2001388458A

Other languages

English (en)

Japanese (ja)

Other versions

JP2003183154A (ja

JP4074457B2 (ja

Filing date

2001-12-20

Publication date

2007-02-22

2001-12-20 Application filed filed Critical

2001-12-20 Priority to JP2001388458A priority Critical patent/JP4074457B2/ja

2001-12-20 Priority claimed from JP2001388458A external-priority patent/JP4074457B2/ja

2003-07-03 Publication of JP2003183154A publication Critical patent/JP2003183154A/ja

2007-02-22 Publication of JP2003183154A5 publication Critical patent/JP2003183154A5/ja

2008-04-09 Application granted granted Critical

2008-04-09 Publication of JP4074457B2 publication Critical patent/JP4074457B2/ja

2021-12-20 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

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HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
229920000669 heparin Polymers 0.000 description 2
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 description 1
229960002897 heparin Drugs 0.000 description 1
229940071643 prefilled syringe Drugs 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
239000000243 solution Substances 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000004659 sterilization and disinfection Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
239000008215 water for injection Substances 0.000 description 1

JP2001388458A 2001-12-20 2001-12-20 ヘパリン溶液入りプレフィルドシリンジ製剤およびその製造方法 Expired - Lifetime JP4074457B2 (ja)