JP2003176273A5 - - Google Patents
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- Publication number
- JP2003176273A5 JP2003176273A5 JP2002375683A JP2002375683A JP2003176273A5 JP 2003176273 A5 JP2003176273 A5 JP 2003176273A5 JP 2002375683 A JP2002375683 A JP 2002375683A JP 2002375683 A JP2002375683 A JP 2002375683A JP 2003176273 A5 JP2003176273 A5 JP 2003176273A5
- Authority
- JP
- Japan
- Prior art keywords
- substituent
- alkyl
- group
- halogen
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 125000000217 alkyl group Chemical group 0.000 description 6
- 229910052739 hydrogen Inorganic materials 0.000 description 5
- 239000001257 hydrogen Substances 0.000 description 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 5
- 125000001424 substituent group Chemical group 0.000 description 5
- 229910052736 halogen Inorganic materials 0.000 description 4
- 150000002367 halogens Chemical class 0.000 description 4
- 125000004433 nitrogen atom Chemical group N* 0.000 description 4
- 125000003545 alkoxy group Chemical group 0.000 description 3
- 125000004103 aminoalkyl group Chemical group 0.000 description 3
- -1 cyano, nitro, amino Chemical group 0.000 description 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000008194 pharmaceutical composition Substances 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 125000004430 oxygen atom Chemical group O* 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- BWZNJVZTAWBIFG-UHFFFAOYSA-N 1-(4-chlorophenyl)-n-[3-cyano-4-(4-morpholin-4-ylpiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide Chemical compound CC1=C(C(=O)NC=2C=C(C(N3CCC(CC3)N3CCOCC3)=CC=2)C#N)C=NN1C1=CC=C(Cl)C=C1 BWZNJVZTAWBIFG-UHFFFAOYSA-N 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 125000005041 acyloxyalkyl group Chemical group 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 description 1
- 125000004414 alkyl thio group Chemical group 0.000 description 1
- 125000000304 alkynyl group Chemical group 0.000 description 1
- 125000003710 aryl alkyl group Chemical group 0.000 description 1
- 125000004104 aryloxy group Chemical group 0.000 description 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 125000000000 cycloalkoxy group Chemical group 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 125000004438 haloalkoxy group Chemical group 0.000 description 1
- 125000001188 haloalkyl group Chemical group 0.000 description 1
- 125000001072 heteroaryl group Chemical group 0.000 description 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 description 1
- 125000005842 heteroatom Chemical group 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 125000005113 hydroxyalkoxy group Chemical group 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 125000003396 thiol group Chemical class [H]S* 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002375683A JP2003176273A (ja) | 1999-02-10 | 2002-12-25 | アミド化合物およびその医薬としての用途 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3336799 | 1999-02-10 | ||
| JP11-33367 | 1999-02-10 | ||
| JP11-198473 | 1999-07-13 | ||
| JP19847399 | 1999-07-13 | ||
| JP2002375683A JP2003176273A (ja) | 1999-02-10 | 2002-12-25 | アミド化合物およびその医薬としての用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000598479A Division JP3419395B2 (ja) | 1999-02-10 | 2000-02-10 | アミド化合物およびその医薬としての用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003176273A JP2003176273A (ja) | 2003-06-24 |
| JP2003176273A5 true JP2003176273A5 (enrdf_load_stackoverflow) | 2007-03-29 |
Family
ID=27288048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002375683A Pending JP2003176273A (ja) | 1999-02-10 | 2002-12-25 | アミド化合物およびその医薬としての用途 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2003176273A (enrdf_load_stackoverflow) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7485657B2 (en) * | 2004-05-12 | 2009-02-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
| WO2005118543A1 (ja) * | 2004-06-03 | 2005-12-15 | Ono Pharmaceutical Co., Ltd. | キナーゼ阻害薬およびその用途 |
| GB0421908D0 (en) * | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
| JP5925688B2 (ja) * | 2010-10-14 | 2016-05-25 | 田辺三菱製薬株式会社 | アミド誘導体およびその用途 |
| PT2635299T (pt) * | 2010-11-02 | 2019-10-14 | Univ Columbia | Métodos de tratamento de distúrbios de perda de cabelo |
| JP5925723B2 (ja) * | 2012-04-13 | 2016-05-25 | 田辺三菱製薬株式会社 | アミド誘導体の医薬用途 |
| JP2015096499A (ja) * | 2013-10-11 | 2015-05-21 | 田辺三菱製薬株式会社 | 医薬組成物 |
| CN113024538B (zh) * | 2019-12-24 | 2022-09-09 | 南开大学 | 吡唑酰胺类化合物及其制备和在防治植物病菌病和杀虫中的应用 |
| CN118344304A (zh) * | 2024-03-19 | 2024-07-16 | 华南农业大学 | 一种布洛芬衍生物及其制备方法和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4134987A (en) * | 1976-01-14 | 1979-01-16 | Huppatz John L | Compounds and compositions |
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2002
- 2002-12-25 JP JP2002375683A patent/JP2003176273A/ja active Pending
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