JP2003034646A - 'shin-ei husai gan'-first-aid chinese medicine for treating cerebrovascular disease(cvd) - Google Patents

'shin-ei husai gan'-first-aid chinese medicine for treating cerebrovascular disease(cvd)

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Publication number
JP2003034646A
JP2003034646A JP2001235565A JP2001235565A JP2003034646A JP 2003034646 A JP2003034646 A JP 2003034646A JP 2001235565 A JP2001235565 A JP 2001235565A JP 2001235565 A JP2001235565 A JP 2001235565A JP 2003034646 A JP2003034646 A JP 2003034646A
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cerebral
drug
cvd
hemorrhage
shin
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JP3479654B2 (en
Inventor
Buntoku Ryu
文徳 劉
Teruhiko Shimoda
輝彦 下田
Unmei Cho
雲明 趙
Shitan Ryu
紫丹 劉
Shichun Ryu
紫▲チュン▼ 劉
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Abstract

PROBLEM TO BE SOLVED: To provide a Chinese medicine without having toxicity and side-effects for treating cerebrovascular diseases(CVD) such as 'cerebral infarction', 'cerebral thrombosis', 'cerebral embolism', 'cerebral hemorrhage', 'subarachnoid hemorrage' and the like. SOLUTION: The Chinese medicine which is formulated by combining with wellknown Chinese remedies. Said Chinese medicine, without having toxicity and side-effects, prevents and treats cerebrovascular diseases. At present, several treating methods are known for curing cerebrovascular diseases, while the treating effects of these methods are not good enough or are attended with some dangers. The 'Shin-ei husai gan' of the present invention makes up for such deffects of these previous treating methods and has remarkable effects in the treatments.

Description

【発明の詳細な説明】 【0001】 【発明の属する技術分野】本発明は脳血管の病気(CV
D)を治療する毒、副作用のない救急中成薬である。具
体的には有名な漢方薬を有効成分として作られた救急中
成薬である。当薬は脳血栓(cerebral inf
arction)、脳血栓形成(cerebral t
hrombosis)、脳栓塞(cerebral e
mbolism)、脳出血(cerebral hem
orrhage)、蛛网膜下腔出血(subarach
noid hemorrhage)などの病気の救急治
療及び予防に効果がある。 【0002】 【従来の技術】現在、国内や外国の西洋医学では脳血管
の病気(CVD)を治療するのに、以下の方法を採用し
ている。 1、脱水剤(dehydrant)と類固醇薬物(st
eroid)治療法、脳水腫(cerebral ed
ema)及び微循環障害(microcirculat
ory disturbance)を改善する。しか
し、このような薬物を使用すると正常な脳部分が脱水の
症状を起こし、血脳障害(bbb)により破壊された脳
血栓の部分の脳水腫が深刻になってしまう。そして、こ
のような薬物は心血輸出量を増加させるため、顱内圧
(intracranial pressure)の高
い患者及び心力衰竭(cardiac failur
c)の患者は使用禁止。血管拡張剤(vasodila
tor)の使用は顱内圧(intracranial
pressure)を高め、出血性脳血栓患者の出血の
部分を拡大してしまう。肝、腎機能の不良或いは低血圧
者には使用しないほうがいい。 2、抗血栓療法、一般的には抗凝剤(decoagul
ant)を使用する。この治療法に関しては、いまだに
医学界では議論があり、そして、出血症状のある患者、
潰瘍(cankcr)の病歴がある人、厳重高血圧病
(hypertension)及び肝、腎の病気のある
患者は使用禁止。 3、抗繊溶薬物(6−安基己酸〈6−aminohex
anolic〉と止血環酸〈tranexamicac
id〉)の使用。最新の観点では正規に使用すると再出
血の発生率を減らすことができない。脳血管の病気(C
VD)の患者には出血の症状があるか、血栓形成の症状
があるので、脱水剤(dehydrant)或いは類固
醇薬物(steroid)、止血薬物(hemosta
t)、凝血薬物(coagulant)などの使用は特
殊有効な救急治療法ではない。その上、単一で毒、副作
用のある部分の治療方法である。その他の治療方法:応
用脳代謝活化剤(activator)、脳保護剤(p
rotective)、高圧羊艙療法(hyperba
ric oxygen chamber therap
y)。これらの治療方法はあまり効果なく、補助治療法
として使われている。手術治療法は難度が高いうえ、発
病部の厳重度合にも制限される。中国の医学における脳
血管の病気(CVD)の救急治療では、“清火去痰、 合、全面的に達した治療の中成薬はない。したがって、
脳血管の病気(CVD)の治療においては特別で理想な
治療薬さえないのだから、まして救急治療の中成薬。 【0003】 【発明が解決しようとする課題】毒、副作用のない脳血
管の病気(CVD)を救急治療する有効な中成薬を開発
することは現代医学界の最も重要な研究課題である。そ
して、本発明の薬はこの課題を解決する唯一の鍵となる
薬物である。迅速で有効に脳血管の病気(CVD)を救
急治療する毒、副作用のない純漢方薬製剤を提供するこ
とは本発明の目的である。 【0004】 【課題を解決するための手段】脳血管病気(CVD)の
発病部は脳にある。中国医学の臓腑弁証学の理論による
と,心、肝、腎の三つの陰陽失調,そして憂、思、悩、
怒或いは過労 実下虚、陰陽不相維系の危急症候を形成する。口眼歪
斜、語言不利、偏身麻木或いは突然昏仆(突然気絶す
る)、不省人事(気を失うまま起きない)、半身不随は
病気の特徴である。発病の特徴は、起病急驟(急に病気
にかかる)、変化迅速、見症多端(症状は様々)、即危
【0005】 【発明の実施の形態】以下は薬剤の成分(重量分) 処方箋の中:牛黄(bezoar)、麝香(mus
k)、氷片(boneol)、羚羊角(cornusa
tgae)は開 醒神、清心豁痰、涼肝息風、定驚除邪
気,通経絡、透肌骨、 血”を原因とした“中風(脳卒中)”の諸症状を取り除
くことができる。本発明の薬―――神英普済丸は以上の
処方でできている。重量比に従って原料を選び、常規製
剤工芸で臨床に適用する丸剤を作る。上の処方箋の中の
どの薬も優良なものを選ぶ。本発明の薬―――神英普済
丸の薬剤は丸剤であり、その製法は:処方箋に記載する
原料となる薬を重量比に従って優良なもの選び、粉粉に
してから篩にかけて、丸剤を作る。珠砂為衣、一粒の重
さは3グラム。本発明の薬―――神英普済丸は脳血管病
気(CVD)を救急治療する効力があり,脳血栓(ce
rebral infarction)、脳栓塞(ce
rebral embolism)、脳出血(cere
bral hemorrhage)の急性期救急には良
好な治療効果がある。 【0006】 【実施例】当発明の発明者――劉 文徳(主任医師)は
医者を勤めて四十年“神英普済丸”を使って様々な脳血
管病気(CVD)の難病を治してきた。以下はその典型
的な病例の一部である。 典型病例: [病例一]氏名:張振生、男、56歳、公務員。199
4年12月31日午後4時、突然目眩し、四肢無力を感
じ、右側の体が動くことができなくなり、口が歪み、話
せなくなり、大小便失禁。即座に遼寧省阜新市第二医院
に入院。“CT”検査の結果“全脳2/3大面積脳栓
塞”と判断され、“脳血栓”の西洋薬で治療するより仕
方がなく、死に至る状態だと告げられました。その患者
には高血圧、高脂血症、動脈硬化症の病歴がある。患者
は午後8時に、当発明――“神英普済丸”を4時間ごと
に一粒服用し、翌朝8時頃、歪んでた口が正常に戻り、
はっきり話せるようになり、四肢にも知覚が戻り、右半
身も軽い運動ができるようになり、大小便の失禁も治っ
た。 [病例二] 氏名:劉剣霞、女、62歳、定年者。糖尿病の患者で、
1999年5月に右半身に力なく、普通に歩けなくな
り、病院で検査した結果“脳血栓”である。“脳血栓”
を治療する各種西洋薬や北京同仁堂の“牛黄安宮丸”四
粒を使ってもまったく効力がない。そのあと、当発明―
―“神英普済丸”を二粒服用し、翌日に症状が消え、自
由に歩けるようになった。“多くの‘牛黄安宮丸’を使
用しても一粒の‘神英普済丸’の効力に及ばない”と患
者が言っていた。 [病例二] 氏名:張桂蘭、女、76歳、家事手伝い。1996年3
月18日の夜、突然頭痛を感じ、口が歪み、肢体が動け
なくなった。入院して“脳溢血”と診断された。顱内圧
(intracranial pressure)を下
げる薬物や止血薬物を使用するほかに、当発明の薬物―
―神英普済丸二粒を使用した。六時間後に症状はすっか
り消え、口の歪みも治り、言語の能力も戻り、支えると
歩くこともできる。 【0007】 【発明の効果】神英普済丸は:脳血栓形成(cereb
ral thrombosis)、脳栓塞(cereb
ral embolism)、脳出血(cerebra
l hemorrhage)、蛛网膜下腔出血(sub
arachnoid hemorrhage)などの脳
血管病気(CVD)を治療する効力がある。当発明薬物
――神英普済丸は脳血管病気(CVD)を治療する救急
漢方薬であり、著しい効力を持っている。現代社会では
数多くの人々が脳血管病気(CVD)で命を失ってい
る。神英普済丸を世に送り出せば、多くの人の命が助け
られる上、脳血管病気(CVD)による後遺症を減らし
たり無くしたりすることにも効果がある。
Description: BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to cerebrovascular disease (CV).
It is a poison for treating D) and an emergency drug with no side effects. Specifically, it is an emergency medicinal product made with famous Chinese herbal medicine as an active ingredient. The drug is cerebral inf
arcion, cerebral thrombus formation (cerebral t
chromosis, cerebral embolism
mbolism, cerebral hemorrhage
orrage, subarachnoid hemorrhage (subalach)
It is effective for emergency treatment and prevention of diseases such as noid hemorrhage. [0002] At present, Western medicine in Japan and abroad employs the following methods for treating cerebrovascular disease (CVD). 1. Dehydrant and similar drug (st
eroid therapy, cerebral edema
ema) and microcirculatory disturbances
ory disturbance). However, when such a drug is used, the normal brain part causes dehydration, and the cerebral edema at the part of the cerebral thrombus destroyed by the blood-brain disorder (bbb) becomes serious. In addition, since such drugs increase cardiac blood export, patients with high intracranial pressure and cardiac failure
Use of c) is prohibited. Vasodilator
tor is used for intracranial pressure (intracranial)
pressure) is increased and the bleeding portion of hemorrhagic cerebral thrombosis patients is enlarged. It should not be used for patients with poor liver or kidney function or low blood pressure. 2. Antithrombotic therapy, generally anticoagulant (decoagul)
ant). There is still debate in the medical community about this treatment, and patients with bleeding symptoms,
Use is prohibited for patients with a history of ulcer, severe hypertension, and liver and kidney disease. 3. Anti-fibrinolytic drug (6-amino acid <6-aminohex
anolitic> and hemostatic cyclic acid <tranexamicac
id>). From the latest point of view, regular use does not reduce the incidence of rebleeding. Cerebrovascular disease (C
VD) patients have bleeding symptoms or thrombosis symptoms, so dehydrants, steroids, hemostatic drugs (hemosta)
t), the use of coagulants, etc. is not a special effective emergency treatment. In addition, it is a single treatment method for poisonous and side effects. Other treatment methods: Applied brain metabolic activators (activators), brain protective agents (p
rotative, hyperbaric acupuncture therapy (hyperba)
ric oxygen chamber therap
y). These treatments are not very effective and are used as adjuvant treatments. Surgical treatment is difficult and is limited by the severity of the affected area. In emergency medicine for cerebrovascular disease (CVD) in Chinese medicine, In other words, there is no medicinal drug that has been fully achieved. Therefore,
In the treatment of cerebrovascular disease (CVD), there is not even a special and ideal treatment, so it is a neutral medicine for emergency treatment. [0003] The development of effective medicinal drugs for the emergency treatment of cerebrovascular diseases (CVD) without poisons and side effects is the most important research subject of the modern medical community. The drug of the present invention is the only key drug that solves this problem. It is an object of the present invention to provide a pure Chinese medicine preparation which is quick and effective and provides emergency treatment for cerebrovascular disease (CVD) and has no side effects. [0004] The pathogenesis of cerebrovascular disease (CVD) is in the brain. According to the theory of visceral dialectics in Chinese medicine, the heart, liver and kidney are three types of yin-yang dysfunction, and sorrow, thought, trouble,
Anger or overwork In fact, it forms a critical symptom of the Yin Yang incompatible system. Oral skewness, wording disadvantage, prejudiced hemp or sudden acupuncture (suddenly faints), conservative personnel (does not wake up), and half-body incontinence are characteristic of the disease. The characteristics of the onset are rapid onset of disease (suddenly illness), rapid change, multiple symptoms (various symptoms), immediate danger DETAILED DESCRIPTION OF THE INVENTION The following are components of a drug (by weight) In the prescription: bezoar, mus
k), ice cubes (boneol), cornusa
tgae) is a god of awakening, Kiyoshishin, Ryokan Breeze, constant insurgency, meridian, skin skin, Can eliminate various symptoms of “middle wind (stroke)” caused by “blood.” The drug of the present invention——Shin-Ei Fujin-maru has been formulated as above. Make pills for clinical application in pharmaceutical crafts.Select any medicine in the above prescription.The medicine of the present invention--The medicine of Shin-Ei Pengsai Maru is a pill, and its manufacturing method is : Select the drug that will be the raw material described in the prescription according to the weight ratio, make it into a powder and sieve it to make a pill. -Shin-Ei Fusaimaru is effective for emergency treatment of cerebrovascular disease (CVD), and cerebral thrombus (ce
rebral infection), cerebral embolism (ce
rebembal embolism, cerebral hemorrhage (cere)
(bral hemorrhage) has an acute therapeutic effect. [Example] The inventor of the present invention-Liu Bunnori (chief doctor) worked as a doctor for 40 years to treat various cerebrovascular diseases (CVD) incurable diseases using "Shin-Ei Fusaimaru" I have done it. The following are some of the typical cases. Typical disease: [Case 1] Name: Zhang Jingsei, male, 56 years old, civil servant. 199
At 4 pm on December 31, 2004, suddenly dizzy, feeling weakness in the limbs, unable to move the right body, distorted mouth, unable to speak, and incontinence of urine. Immediately admitted to the second clinic in Fuxin City, Liaoning Province. As a result of the “CT” test, it was judged that the whole brain had a 2/3 large area cerebral embolism. The patient has a history of hypertension, hyperlipidemia, arteriosclerosis. The patient took the invention-"Shin-Ei Fujin-maru" every 4 hours at 8pm and the distorted mouth returned to normal around 8am the next morning,
I became able to speak clearly, my limbs returned to my sensation, my right body was able to do light exercise, and incontinence of urine and urine was cured. [Case 2] Name: Liu Kengo, female, 62 years old, retired. A patient with diabetes,
In May 1999, the right side of the body was weak and unable to walk normally. “Brain thrombus”
The use of various Western medicines for treatment and four “Beef Huang An Maru” from Beijing Dojindo has no effect. Then, the present invention
―Two “Shingu Fusaimaru” were taken, and the symptoms disappeared the next day and I was able to walk freely. The patient said, “Using a lot of 'Ushi Huang An Maru” doesn't reach the efficacy of a single “Shingei Fusai Maru”. [Disease 2] Name: Lan Zhang, female, 76 years old, helping with housework. 1996 3
On the night of March 18th, I suddenly felt a headache, distorted mouth and became unable to move my limbs. He was hospitalized and was diagnosed with “brain overflow”. In addition to using drugs that reduce intracranial pressure and hemostatic drugs,
―We used two Shin-Ei Fusaimaru. Six hours later, the symptoms disappear completely, the mouth is cured, the language ability returns, and you can walk when you support it. [Effects of the Invention] Shin-Ei Fusaimaru: Cerebral thrombus formation (cereb)
ral thrombosis, cerebrum
ral embolism, cerebral hemorrhage (cerebra)
l hemorrhage), subretinal hemorrhage (sub
It is effective in treating cerebrovascular diseases (CVD) such as arachnoid hemorrhage. The drug of the present invention—Shingei Fusaimaru is an emergency Chinese herbal medicine for treating cerebrovascular disease (CVD) and has a remarkable effect. Many people in modern society have lost their lives due to cerebrovascular disease (CVD). Sending Shinhei Fusaimaru to the world will help many people's lives and reduce or eliminate the sequelae of cerebrovascular disease (CVD).

─────────────────────────────────────────────────────
【手続補正書】 【提出日】平成14年4月3日(2002.4.3) 【手続補正1】 【補正対象書類名】明細書 【補正対象項目名】特許請求の範囲 【補正方法】変更 【補正内容】 【特許請求の範囲】 【請求項1】“神英普済丸”は脳血管病を救急治療する
中成薬である。その特徴は漢方薬の組合物であって、組
み合わせが以下の成分(重量分)である。 【請求項2】請求項1記載の“神英普済丸”は丸薬であ
る。 【請求項3】請求項1記載の“神英普済丸”は脳血栓
(cerebralinfarction).脳血栓形
成(cerebral thrombosis)、脳栓
塞(cerebral embolism)、脳出血
(cerebral hemorrhage)、蛛网膜
下腔出血(subarachnoidhemorrha
ge)等の脳血管病の救急治療及び予防に効果がある。
──────────────────────────────────────────────────── ───
[Procedure Amendment] [Submission Date] April 3, 2002 (2002.4.3) [Procedure Amendment 1] [Document Name to be Amended] Description [Item Name to be Amended] Claims [Amendment Method] Change [Contents of amendment] [Claims] [Claim 1] “Shin-Ei Fumsai Maru” is a neutral drug for emergency treatment of cerebrovascular disease. The feature is a combination of Chinese medicines, and the combination is the following components (weight parts). 2. “Shin-Ei Fusaimaru” according to claim 1 is a pill. 3. The “Shinei Fusaimaru” according to claim 1 is a cerebral thrombus. Cerebral thrombosis, cerebral embolism, cerebral hemorrhage, subarachnoid hemorrhagia
ge) and other emergency treatment and prevention of cerebrovascular diseases.

───────────────────────────────────────────────────── フロントページの続き (71)出願人 501307103 劉 紫丹 中国広東省深▲セン▼市福田区上梅林奥士 達宿舎802室 (71)出願人 501307114 劉 紫▲チュン▼ 中国広東省深▲セン▼市福田区上梅林奥士 達宿舎802室 (72)発明者 劉 文徳 中国広東省深▲セン▼市福田区上梅林奥士 達宿舎802室 (72)発明者 下田 輝彦 茨城県土浦市神立中央4−1−4−31 (72)発明者 趙 雲明 茨城県土浦市神立中央4−1−4−31 (72)発明者 劉 紫丹 中国広東省深▲セン▼市福田区上梅林奥士 達宿舎802室 (72)発明者 劉 紫▲チュン▼ 中国広東省深▲セン▼市福田区上梅林奥士 達宿舎802室 Fターム(参考) 4C076 AA36 BB01 CC11 CC14 4C087 AA01 AA02 BB33 BB42 BB48 BB53 MA02 MA35 NA14 ZA36 ZA54 4C088 AB12 AB62 AD14 MA08 MA35 NA14 ZA36 ZA54    ─────────────────────────────────────────────────── ─── Continued front page    (71) Applicant 501307103             Liu Shitan             Shenzhen, Guangdong Province, China             802 rooms (71) Applicant 501307114             Liu Purple ▲ Chun ▼             Shenzhen, Guangdong Province, China             802 rooms (72) Inventor Liu Wende             Shenzhen, Guangdong Province, China             802 rooms (72) Inventor Teruhiko Shimoda             4-1-4-31 Shinchō Chuo, Tsuchiura City, Ibaraki Prefecture (72) Inventor 明 Unmei             4-1-4-31 Shinchō Chuo, Tsuchiura City, Ibaraki Prefecture (72) Inventor Liu Shitan             Shenzhen, Guangdong Province, China             802 rooms (72) Inventor Liu Purple             Shenzhen, Guangdong Province, China             802 rooms F-term (reference) 4C076 AA36 BB01 CC11 CC14                 4C087 AA01 AA02 BB33 BB42 BB48                       BB53 MA02 MA35 NA14 ZA36                       ZA54                 4C088 AB12 AB62 AD14 MA08 MA35                       NA14 ZA36 ZA54

Claims (1)

【特許請求の範囲】 【請求項1】当薬は有名な漢方薬を組み合わせによりで
きた薬であり、主に脳血管の病気(CVD)を治療する
薬である。 【請求項2】有名な漢方薬の混合物というところはその
特徴であり、組み合わせが厳密な薬剤である。 【請求項3】短期間で病状を押さえることもその特徴で
ある。 【請求項4】成分として以下の漢方薬を使用している。
牛黄(bezoar) 麝香(musk) 羚羊角(c
ornu satgae) 氷片(boneol) 郁
金(curcuma root) 乳香(boswel
lin) 没薬(myrrh) 芽皀(英語なし) 陳
皮(tangerine peel) 琥珀(gles
site) 【請求項5】“神英普済丸”は脳血管の病気(CVD)
を治療する救急毒、副作用のない中成薬であり、脳血管
の病気(CVD)の治療及び予防に効果がある。 【請求項6】“神英普済丸”は 【請求項5】に記載しているように脳血栓(cereb
ral infarction)、脳血栓形成(cer
ebralthrombosis)、脳栓塞(cere
bral embolism)、脳出血(cerebr
al hemorrhage)、蛛网膜下腔出血(su
barachnoid hemorrhage)などの
病気の救急治療及び予防に効果がある。 【請求項7】当薬は 【請求項4】に記載している漢方薬を成分とし、“神英
普済丸”の薬剤の特徴は丸薬である。
[Claim 1] This drug is a medicine made by combining famous Chinese herbal medicines, mainly for treating cerebrovascular disease (CVD). 2. The famous mixture of herbal medicines is its characteristic and the combination is a strict drug. [3] The feature is to suppress the medical condition in a short period of time. 4. The following Chinese medicines are used as ingredients.
Bezoar musk ram horn (c
ornu satgae ice cubes (boneol) curcuma root boswel
lin) myrrh, bud (no english) tangerine peel, gles
(Site) [Claim 5] “Shin-Ei Fusaimaru” is a disease of cerebrovascular
It is a first-aid drug that does not have side effects and is effective in the treatment and prevention of cerebrovascular disease (CVD). 6. “Shingu Fusaimaru” is a cerebral thrombus as described in [Claim 5].
ral induction, cerebral thrombus formation (cer
ebralthrombosis, cerebral embolism (cere)
bral embolism, cerebral hemorrhage (cerebr)
al hemorrhage), subretinal hemorrhage (su
It is effective for emergency treatment and prevention of diseases such as barachnoid hemorrhage. [7] The present drug comprises the Chinese herbal medicine described in [4] as a component, and the characteristic of the drug of “Shinei Fusaimaru” is a pill.
JP2001235565A 2001-06-29 2001-06-29 “Shingu Fusaimaru”-Emergency middle-aged medicine (Chinese medicine) for treating cerebrovascular disease (CVD) Expired - Fee Related JP3479654B2 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008075862A1 (en) * 2006-12-16 2008-06-26 Pusan National University Industry-University Cooperation Foundation A method for preparing materials having antithrombotic activity from muskrat musk and materials obtained from the method
CN104524426A (en) * 2014-12-05 2015-04-22 张洪胜 Traditional Chinese medicine for treating cerebral hemorrhage

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008075862A1 (en) * 2006-12-16 2008-06-26 Pusan National University Industry-University Cooperation Foundation A method for preparing materials having antithrombotic activity from muskrat musk and materials obtained from the method
CN104524426A (en) * 2014-12-05 2015-04-22 张洪胜 Traditional Chinese medicine for treating cerebral hemorrhage

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