JP2002541435A5 - - Google Patents

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Publication number
JP2002541435A5
JP2002541435A5 JP2000598857A JP2000598857A JP2002541435A5 JP 2002541435 A5 JP2002541435 A5 JP 2002541435A5 JP 2000598857 A JP2000598857 A JP 2000598857A JP 2000598857 A JP2000598857 A JP 2000598857A JP 2002541435 A5 JP2002541435 A5 JP 2002541435A5
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JP
Japan
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reaction mixture
target
size exclusion
molecular weight
less
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JP2000598857A
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English (en)
Japanese (ja)
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JP2002541435A (ja
JP3788909B2 (ja
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Priority claimed from PCT/US2000/003562 external-priority patent/WO2000047999A1/en
Publication of JP2002541435A publication Critical patent/JP2002541435A/ja
Publication of JP2002541435A5 publication Critical patent/JP2002541435A5/ja
Application granted granted Critical
Publication of JP3788909B2 publication Critical patent/JP3788909B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000598857A 1999-02-12 2000-02-11 親和力配位子について複合生理学的材料をスクリーニングする高処理量のサイズ排除法 Expired - Fee Related JP3788909B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11996699P 1999-02-12 1999-02-12
US60/119,966 1999-02-12
PCT/US2000/003562 WO2000047999A1 (en) 1999-02-12 2000-02-11 High throughput size-exclusive method of screening complex biological materials for affinity ligands

Publications (3)

Publication Number Publication Date
JP2002541435A JP2002541435A (ja) 2002-12-03
JP2002541435A5 true JP2002541435A5 (https=) 2005-10-13
JP3788909B2 JP3788909B2 (ja) 2006-06-21

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ID=22387470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000598857A Expired - Fee Related JP3788909B2 (ja) 1999-02-12 2000-02-11 親和力配位子について複合生理学的材料をスクリーニングする高処理量のサイズ排除法

Country Status (5)

Country Link
US (1) US7179592B2 (https=)
EP (1) EP1151301A4 (https=)
JP (1) JP3788909B2 (https=)
CA (1) CA2362052A1 (https=)
WO (1) WO2000047999A1 (https=)

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US6528098B2 (en) * 1996-10-22 2003-03-04 Advanced Viral Research Corp. Preparation of a therapeutic composition
US6837977B1 (en) * 1999-06-24 2005-01-04 Cetek Corporation Capillary electrophoresis method for screening for affinity ligands using a detectable competitive ligand
MXPA02008253A (es) * 2000-02-25 2002-11-29 Wyeth Corp Metodos de diseno de farmacos basados en la estructura usando em/rmn.
JP2004534519A (ja) * 2000-11-17 2004-11-18 アルフレッド イー． スランツ 標的分子機能の決定と薬物リード化合物の同定に関する方法
DE10125258A1 (de) 2001-05-23 2003-01-09 November Ag Molekulare Medizin Verfahren zur Bestimmung des Bindeverhaltens von an Ziel-Molekülen spezifisch bindenden Liganden
US6833238B2 (en) 2002-01-04 2004-12-21 Applera Corporation Petal-array support for use with microplates
WO2004037848A2 (en) * 2002-05-17 2004-05-06 Slanetz Alfred E Process for determining target function and identifying drug leads
US20040018559A1 (en) * 2002-07-26 2004-01-29 Applera Corporation Size-exclusion ion-exchange particles
US20050196856A1 (en) * 2004-02-18 2005-09-08 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20050181378A1 (en) * 2004-02-18 2005-08-18 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20060160122A1 (en) * 2004-02-18 2006-07-20 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
WO2006015796A1 (en) * 2004-08-09 2006-02-16 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for high-throughput screening of test molecules binding to target molecules
US7169425B2 (en) 2004-09-17 2007-01-30 Solae, Llc Size exclusion chromatography process for the preparation of an improved soy protein-containing composition
US20060062889A1 (en) * 2004-09-17 2006-03-23 Solae, Llc. Soy protein-containing composition
JP4735289B2 (ja) * 2005-01-31 2011-07-27 株式会社島津製作所 標的化合物と結合する反応化合物を特定するスクリーニング方法及び装置
US20060169640A1 (en) * 2005-02-01 2006-08-03 Hubert Quinn High throughput screening, purification and recovery system for large and small molecules
AU2005332686B2 (en) * 2005-06-03 2012-09-27 Ohr Pharmaceutical, Inc. Methods for providing palliative care with AVR118
WO2010053941A2 (en) * 2008-11-04 2010-05-14 Duke University Affinity displacement molecular separation
FI20115785A0 (fi) * 2011-08-08 2011-08-08 Thermo Fisher Scientific Oy Menetelmä ja laite automaattiseen analyysiin
US9891149B2 (en) 2011-08-08 2018-02-13 Thermo Fisher Scientific Oy Method and apparatus for automated analysis
CN102818868B (zh) * 2012-08-27 2013-11-20 浙江大学 复杂天然产物中活性成分筛选方法及应用
US11071927B2 (en) * 2017-11-15 2021-07-27 Arup Laboratories, Inc. Separating and quantifying unbound target analytes from biological samples
CN114555204A (zh) * 2019-09-10 2022-05-27 皮尔斯生物科技有限公司 样品制备组合物、装置、系统和方法
CN112649517B (zh) * 2019-10-12 2021-10-15 中国科学院大连化学物理研究所 一种从生物体代谢物中筛选靶蛋白配体的方法
JP7327096B2 (ja) * 2019-11-13 2023-08-16 株式会社島津製作所 分子の分離方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891742A (en) * 1995-01-19 1999-04-06 Chiron Corporation Affinity selection of ligands by mass spectroscopy
US5630924A (en) 1995-04-20 1997-05-20 Perseptive Biosystems, Inc. Compositions, methods and apparatus for ultrafast electroseparation analysis
JP3737516B2 (ja) * 1995-06-26 2006-01-18 パーセプティブ バイオシステムズ，インコーポレーテッド 高速自動化連続流、多次元分子選別および分析
US5783397A (en) 1995-12-11 1998-07-21 Northeastern University Screening natural samples for new therapeutic compounds using capillary electrophoresis
US6207861B1 (en) * 1998-01-05 2001-03-27 Neogenesis, Inc. Method for producing and screening mass coded combinatorial libraries for drug discovery and target validation
DE10028186A1 (de) * 2000-06-09 2002-09-19 November Ag Molekulare Medizin Verfahren zur Bestimmung der Menge von an Ziel-Molekülen gebundenen Liganden

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