JP2002540423A - 分析システム - Google Patents

分析システム

Info

Publication number
JP2002540423A
JP2002540423A JP2000608162A JP2000608162A JP2002540423A JP 2002540423 A JP2002540423 A JP 2002540423A JP 2000608162 A JP2000608162 A JP 2000608162A JP 2000608162 A JP2000608162 A JP 2000608162A JP 2002540423 A JP2002540423 A JP 2002540423A
Authority
JP
Japan
Prior art keywords
radiation
sample
excitation
emitted
wavelength
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000608162A
Other languages
English (en)
Japanese (ja)
Inventor
ジョナサン マーク クーパー、
ヴァンサン ブノワ、
ジェイムズ ステュアート エイチソン、
Original Assignee
ザ ユニヴァースティ コート オブ ザ ユニヴァースティ オブ グラスゴウ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ ユニヴァースティ コート オブ ザ ユニヴァースティ オブ グラスゴウ filed Critical ザ ユニヴァースティ コート オブ ザ ユニヴァースティ オブ グラスゴウ
Publication of JP2002540423A publication Critical patent/JP2002540423A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2000608162A 1999-03-26 2000-03-27 分析システム Pending JP2002540423A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9906929.6A GB9906929D0 (en) 1999-03-26 1999-03-26 Assay system
GB9906929.6 1999-03-26
PCT/GB2000/001050 WO2000058715A2 (en) 1999-03-26 2000-03-27 Assay system

Publications (1)

Publication Number Publication Date
JP2002540423A true JP2002540423A (ja) 2002-11-26

Family

ID=10850367

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000608162A Pending JP2002540423A (ja) 1999-03-26 2000-03-27 分析システム

Country Status (5)

Country Link
EP (1) EP1166092A2 (de)
JP (1) JP2002540423A (de)
AU (1) AU3440900A (de)
GB (1) GB9906929D0 (de)
WO (1) WO2000058715A2 (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004257737A (ja) * 2003-02-24 2004-09-16 Mitsui Eng & Shipbuild Co Ltd バイオチップ読み取り装置
JP2008523383A (ja) * 2004-12-10 2008-07-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マルチスポット調査装置
JP2009501932A (ja) * 2005-07-21 2009-01-22 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 複数スポット配置を使った励起検出装置
JP2009516846A (ja) * 2005-11-23 2009-04-23 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 多波長構成を使用する光励起のための装置
JP2020531887A (ja) * 2018-01-08 2020-11-05 イラミーナ インコーポレーテッド 構造化照明を用いたアクティブセンサ検出器の多重化

Families Citing this family (29)

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US7410793B2 (en) 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
US7423750B2 (en) 2001-11-29 2008-09-09 Applera Corporation Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
US7387891B2 (en) 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
US20050279949A1 (en) 1999-05-17 2005-12-22 Applera Corporation Temperature control for light-emitting diode stabilization
EP1409721A2 (de) * 2000-11-13 2004-04-21 Gnothis Holding SA Nachweis von nukleinsäure-polymorphismen
DE10126083A1 (de) * 2001-05-29 2002-12-05 Gnothis Holding Sa Ecublens Verwendung von optischen Diffraktionselementen in Nachweisverfahren
JP4834242B2 (ja) * 2001-05-30 2011-12-14 オリンパス株式会社 蛍光読み取り装置
US7223985B2 (en) 2001-08-28 2007-05-29 Rudolf Rigler Single-channel multicolored correlation analysis
US6744502B2 (en) 2001-09-28 2004-06-01 Pe Corporation (Ny) Shaped illumination geometry and intensity using a diffractive optical element
US7635588B2 (en) 2001-11-29 2009-12-22 Applied Biosystems, Llc Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
DE10160987B4 (de) * 2001-12-05 2005-08-04 Siemens Ag Baueinheit zur simultanen, optischen Beleuchtung einer Vielzahl von Proben
DE10200499A1 (de) * 2002-01-03 2003-07-10 Zeiss Carl Jena Gmbh Verfahren und/oder Anordnung zur Identifikation von fluoreszierenden, lumineszierenden und/oder absorbierenden Substanzen auf und/oder in Probenträgern
US9157860B2 (en) 2002-05-16 2015-10-13 Applied Biosystems, Llc Achromatic lens array
US6982166B2 (en) * 2002-05-16 2006-01-03 Applera Corporation Lens assembly for biological testing
AU2003243281A1 (en) * 2002-05-17 2003-12-02 Applera Corporation Optical instrument includung excitation source
JP2005526253A (ja) 2002-05-17 2005-09-02 アプレラ コーポレイション 励起波長による複数の蛍光シグナルを分化するための装置および方法
US6750963B2 (en) * 2002-05-21 2004-06-15 Agilent Technologies, Inc. Imaging systems for signals on a surface
US7173701B2 (en) * 2004-02-13 2007-02-06 Kaiwood Technology Co., Ltd. CCD-based biochip reader
CZ299489B6 (cs) * 2005-01-12 2008-08-13 Ústav fotoniky a elektroniky AV CR, v. v. i. Zpusob spektroskopie povrchových plazmonu pro senzory s povrchovými plazmony a senzorový element k provádení tohoto zpusobu
US7805081B2 (en) * 2005-08-11 2010-09-28 Pacific Biosciences Of California, Inc. Methods and systems for monitoring multiple optical signals from a single source
US20100014296A1 (en) * 2008-07-16 2010-01-21 Chuang Ping Han Light distribution board having gratings with multiple focuses
WO2010150167A1 (en) * 2009-06-24 2010-12-29 Koninklijke Philips Electronics N.V. Optical biosensor with focusing optics
CN102865999B (zh) * 2011-07-08 2015-03-04 中国科学院微电子研究所 Led光学特性检测方法及检测装置
CN103969188A (zh) * 2013-02-01 2014-08-06 苏州英敏基生物技术有限公司 基于ccd或cmos图像传感器的酶标仪检测系统
US9863880B2 (en) * 2013-11-17 2018-01-09 Quantum-Si Incorporated Optical system and assay chip for probing, detecting and analyzing molecules
EP3137878A1 (de) * 2014-04-30 2017-03-08 Instrumentation Laboratory Company Verfahren und systeme für blutgerinnungstests am versorgungsort durch optische detektion
US10190981B2 (en) 2014-05-08 2019-01-29 The Governing Council Of The University Of Toronto Multimode spectroscopy apparatuses and methods
CN106353320A (zh) * 2016-09-12 2017-01-25 北京纳迅科技股份有限公司 便携式生物芯片阅读仪
EP4379355A1 (de) * 2022-11-29 2024-06-05 Gnothis Holding AG Analyse von einzelmolekül-ereignissen mit hohem durchsatz

Family Cites Families (13)

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JPS6035205A (ja) * 1983-08-05 1985-02-23 Machida Oputo Giken:Kk 物体各部までの距離検出方法及びこれに使用する回折スポツト投影部
DE3650524T2 (de) * 1985-09-30 1996-11-21 Molecular Devices Corp Photometrisches Vielortmesssystem mit einer Quelle
US5053619A (en) * 1988-08-12 1991-10-01 Hitachi, Ltd. Variable density scanning apparatus
DE4030699C1 (de) * 1990-09-28 1991-10-10 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
ES2123063T3 (es) * 1992-09-14 1999-01-01 Stanford Res Inst Int Marcadores convertidores al alza para ensayos biologicos y otros mediante tecnicas de excitacion laser.
US5959098A (en) * 1996-04-17 1999-09-28 Affymetrix, Inc. Substrate preparation process
WO1997034171A2 (en) * 1996-02-28 1997-09-18 Johnson Kenneth C Microlens scanner for microlithography and wide-field confocal microscopy
GB2315131B (en) * 1996-07-10 2000-11-29 Cambridge Imaging Ltd Improvements in and relating to imaging
DE19725050C2 (de) * 1997-06-13 1999-06-24 Fraunhofer Ges Forschung Anordnung zur Detektion biochemischer oder chemischer Substanzen mittels Fluoreszenzlichtanregung und Verfahren zu deren Herstellung
DE19748211A1 (de) * 1997-10-31 1999-05-06 Zeiss Carl Fa Optisches Array-System und Reader für Mikrotiterplatten
EP0947249A1 (de) * 1998-03-18 1999-10-06 Corning Incorporated Extrudierte Matrixplatte mit hoher Dichte
DE29810554U1 (de) * 1998-06-09 1998-10-29 Krauser, Peter J., 66271 Kleinblittersdorf Platte
US6455861B1 (en) * 1998-11-24 2002-09-24 Cambridge Research & Instrumentation, Inc. Fluorescence polarization assay system and method

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004257737A (ja) * 2003-02-24 2004-09-16 Mitsui Eng & Shipbuild Co Ltd バイオチップ読み取り装置
JP2008523383A (ja) * 2004-12-10 2008-07-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マルチスポット調査装置
JP2009501932A (ja) * 2005-07-21 2009-01-22 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 複数スポット配置を使った励起検出装置
JP2009516846A (ja) * 2005-11-23 2009-04-23 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 多波長構成を使用する光励起のための装置
JP2020531887A (ja) * 2018-01-08 2020-11-05 イラミーナ インコーポレーテッド 構造化照明を用いたアクティブセンサ検出器の多重化
JP7026147B2 (ja) 2018-01-08 2022-02-25 イラミーナ インコーポレーテッド 構造化照明を用いたアクティブセンサ検出器の多重化

Also Published As

Publication number Publication date
WO2000058715A3 (en) 2001-03-08
EP1166092A2 (de) 2002-01-02
GB9906929D0 (en) 1999-05-19
AU3440900A (en) 2000-10-16
WO2000058715A2 (en) 2000-10-05

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