JP2002534995A - Ｈｅｒ−２結合アンタゴニスト - Google Patents
Ｈｅｒ−２結合アンタゴニストInfo
- Publication number
- JP2002534995A JP2002534995A JP2000595705A JP2000595705A JP2002534995A JP 2002534995 A JP2002534995 A JP 2002534995A JP 2000595705 A JP2000595705 A JP 2000595705A JP 2000595705 A JP2000595705 A JP 2000595705A JP 2002534995 A JP2002534995 A JP 2002534995A
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- amino acids
- isolated
- ecd
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US09/234,208 US7393823B1 (en) | 1999-01-20 | 1999-01-20 | HER-2 binding antagonists |
| PCT/US2000/001484 WO2000044403A1 (en) | 1999-01-20 | 2000-01-20 | Her-2 binding antagonists |
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| CA (1) | CA2361181C (enExample) |
| WO (1) | WO2000044403A1 (enExample) |
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| US6294349B1 (en) | 1999-03-01 | 2001-09-25 | University Of Mississippi Medical Ctr. | Method of diagnosing and monitoring malignant breast carcinomas |
| WO2001001748A2 (en) | 1999-07-02 | 2001-01-11 | Genentech, Inc. | Peptide compounds that bind her2 |
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| WO2003014159A1 (en) * | 2001-08-03 | 2003-02-20 | Commonwealth Scientific And Industrial Research Organisation | Methods of screening based on the egf receptor crystal structure |
| US7585509B2 (en) * | 2002-07-03 | 2009-09-08 | The Curators Of The University Of Missouri | Erb-2 receptor targeting peptide |
| EA200701782A3 (ru) | 2003-04-24 | 2008-04-28 | Инсайт Корпорейшн | Производные азаспироалканов в качестве ингибиторов металлопротеаз |
| JP2007525187A (ja) * | 2003-05-16 | 2007-09-06 | レセプター・バイオロジクス・インコーポレイテッド | イントロン融合タンパク質、ならびにその同定方法および使用方法 |
| CA2565974A1 (en) * | 2004-05-14 | 2005-12-01 | Receptor Biologix, Inc. | Cell surface receptor isoforms and methods of identifying and using the same |
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| WO2006119510A2 (en) * | 2005-05-04 | 2006-11-09 | Receptor Biologix, Inc. | Isoforms of receptor for advanced glycation end products (rage) and methods of identifying and using same |
| US20090170769A1 (en) * | 2005-05-13 | 2009-07-02 | Pei Jin | Cell surface receptor isoforms and methods of identifying and using the same |
| CA2628928A1 (en) * | 2005-11-10 | 2007-05-24 | Receptor Biologix, Inc. | Hepatocyte growth factor intron fusion proteins |
| US7910108B2 (en) * | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
| KR20090031897A (ko) * | 2006-06-12 | 2009-03-30 | 리셉터 바이오로직스 인크 | 전-세포 표면 수용체-특이적 치료제 |
| WO2008005983A2 (en) * | 2006-07-06 | 2008-01-10 | Molecular Logix, Inc. | Pan-her antagonists and methods of use |
| TW200932257A (en) * | 2007-10-16 | 2009-08-01 | Receptor Biologix Inc | Compositions comprising optimized Her1 and Her3 multimers and methods of use thereof |
| NZ596468A (en) * | 2009-05-14 | 2013-11-29 | Nestec Sa | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| CA2924241A1 (en) * | 2013-09-12 | 2015-03-19 | Thomas Jefferson University | Novel delivery compositions and methods of using same |
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| WO2023168426A1 (en) | 2022-03-03 | 2023-09-07 | Enosi Therapeutics Corporation | Compositions and cells containing mixtures of oligo-trap fusion proteins (ofps) and uses thereof |
| WO2024186690A2 (en) | 2023-03-03 | 2024-09-12 | Enosi Therapeutics Corporation | Oligo-trap fusion proteins (ofps) and uses thereof |
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2000
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- 2000-01-20 CA CA2361181A patent/CA2361181C/en not_active Expired - Fee Related
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- 2000-07-31 US US09/630,155 patent/US6414130B1/en not_active Expired - Fee Related
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2008
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2011
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| US20090270316A1 (en) | 2009-10-29 |
| EP1144004A1 (en) | 2001-10-17 |
| AU777422B2 (en) | 2004-10-14 |
| US20120088255A1 (en) | 2012-04-12 |
| AU4795100A (en) | 2000-08-18 |
| US7939080B2 (en) | 2011-05-10 |
| US7393823B1 (en) | 2008-07-01 |
| CA2361181A1 (en) | 2000-08-03 |
| EP1144004A4 (en) | 2002-09-04 |
| CA2361181C (en) | 2011-01-04 |
| WO2000044403A1 (en) | 2000-08-03 |
| US6414130B1 (en) | 2002-07-02 |
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