CA2361181C - Her-2 binding antagonists - Google Patents
Her-2 binding antagonists Download PDFInfo
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- CA2361181C CA2361181C CA2361181A CA2361181A CA2361181C CA 2361181 C CA2361181 C CA 2361181C CA 2361181 A CA2361181 A CA 2361181A CA 2361181 A CA2361181 A CA 2361181A CA 2361181 C CA2361181 C CA 2361181C
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- 239000003656 tris buffered saline Substances 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 230000005751 tumor progression Effects 0.000 description 1
- LSGOVYNHVSXFFJ-UHFFFAOYSA-N vanadate(3-) Chemical compound [O-][V]([O-])([O-])=O LSGOVYNHVSXFFJ-UHFFFAOYSA-N 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- NLIVDORGVGAOOJ-MAHBNPEESA-M xylene cyanol Chemical compound [Na+].C1=C(C)C(NCC)=CC=C1C(\C=1C(=CC(OS([O-])=O)=CC=1)OS([O-])=O)=C\1C=C(C)\C(=[NH+]/CC)\C=C/1 NLIVDORGVGAOOJ-MAHBNPEESA-M 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/234,208 US7393823B1 (en) | 1999-01-20 | 1999-01-20 | HER-2 binding antagonists |
| US09/234,208 | 1999-01-20 | ||
| PCT/US2000/001484 WO2000044403A1 (en) | 1999-01-20 | 2000-01-20 | Her-2 binding antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2361181A1 CA2361181A1 (en) | 2000-08-03 |
| CA2361181C true CA2361181C (en) | 2011-01-04 |
Family
ID=22880399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2361181A Expired - Fee Related CA2361181C (en) | 1999-01-20 | 2000-01-20 | Her-2 binding antagonists |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US7393823B1 (enExample) |
| EP (1) | EP1144004A4 (enExample) |
| JP (1) | JP2002534995A (enExample) |
| AU (1) | AU777422B2 (enExample) |
| CA (1) | CA2361181C (enExample) |
| WO (1) | WO2000044403A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6541214B1 (en) | 1998-11-13 | 2003-04-01 | Oregon Heath Science University | N-terminally truncated HER-2/neu protein as a cancer prognostic indicator |
| US7393823B1 (en) | 1999-01-20 | 2008-07-01 | Oregon Health And Science University | HER-2 binding antagonists |
| US7625859B1 (en) * | 2000-02-16 | 2009-12-01 | Oregon Health & Science University | HER-2 binding antagonists |
| US7396810B1 (en) * | 2000-08-14 | 2008-07-08 | Oregon Health Sciences University | Compositions and methods for treating cancer by modulating HER-2 and EGF receptors |
| US6294349B1 (en) | 1999-03-01 | 2001-09-25 | University Of Mississippi Medical Ctr. | Method of diagnosing and monitoring malignant breast carcinomas |
| CA2373721C (en) | 1999-07-02 | 2013-10-15 | Genentech, Inc. | Compounds that bind her2 |
| US6435873B1 (en) | 2000-10-10 | 2002-08-20 | 3M Innovative Properties Company | Medication delivery devices |
| WO2003014159A1 (en) * | 2001-08-03 | 2003-02-20 | Commonwealth Scientific And Industrial Research Organisation | Methods of screening based on the egf receptor crystal structure |
| AU2003249728A1 (en) | 2002-07-03 | 2004-01-23 | The Curators Of The University Of Missouri | ErbB-2 RECEPTOR TARGETING PEPTIDE |
| WO2004096139A2 (en) | 2003-04-24 | 2004-11-11 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| JP2007525187A (ja) * | 2003-05-16 | 2007-09-06 | レセプター・バイオロジクス・インコーポレイテッド | イントロン融合タンパク質、ならびにその同定方法および使用方法 |
| US20060286102A1 (en) * | 2004-05-14 | 2006-12-21 | Pei Jin | Cell surface receptor isoforms and methods of identifying and using the same |
| AU2005294347A1 (en) * | 2004-10-05 | 2006-04-20 | Oregon Health And Science University | Compositions and methods for treating disease |
| US20070087406A1 (en) * | 2005-05-04 | 2007-04-19 | Pei Jin | Isoforms of receptor for advanced glycation end products (RAGE) and methods of identifying and using same |
| US20090170769A1 (en) * | 2005-05-13 | 2009-07-02 | Pei Jin | Cell surface receptor isoforms and methods of identifying and using the same |
| WO2007058776A2 (en) * | 2005-11-10 | 2007-05-24 | Receptor Biologix, Inc. | Hepatocyte growth factor intron fusion proteins |
| WO2007143600A2 (en) * | 2006-06-05 | 2007-12-13 | Incyte Corporation | Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases |
| CA2655205A1 (en) * | 2006-06-12 | 2007-12-21 | Receptor Biologix Inc. | Pan-cell surface receptor- specific therapeutics |
| WO2008005983A2 (en) * | 2006-07-06 | 2008-01-10 | Molecular Logix, Inc. | Pan-her antagonists and methods of use |
| MX2010003757A (es) * | 2007-10-16 | 2010-04-27 | Symphogen As | Composiciones que comprenden multimeros optimizados de her1 y her3 y sus metodos de uso. |
| CA2761777A1 (en) * | 2009-05-14 | 2010-11-18 | Prometheus Laboratories Inc. | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| EP3043780A4 (en) * | 2013-09-12 | 2017-04-26 | Thomas Jefferson University | Novel delivery compositions and methods of using same |
| WO2018071864A1 (en) | 2016-10-13 | 2018-04-19 | Thomas Jefferson University | Delivery compositions, and methods of making and using same |
| WO2023168426A1 (en) | 2022-03-03 | 2023-09-07 | Enosi Therapeutics Corporation | Compositions and cells containing mixtures of oligo-trap fusion proteins (ofps) and uses thereof |
| WO2024186690A2 (en) | 2023-03-03 | 2024-09-12 | Enosi Therapeutics Corporation | Oligo-trap fusion proteins (ofps) and uses thereof |
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-
1999
- 1999-01-20 US US09/234,208 patent/US7393823B1/en not_active Expired - Fee Related
-
2000
- 2000-01-20 CA CA2361181A patent/CA2361181C/en not_active Expired - Fee Related
- 2000-01-20 AU AU47951/00A patent/AU777422B2/en not_active Ceased
- 2000-01-20 EP EP00930067A patent/EP1144004A4/en not_active Withdrawn
- 2000-01-20 WO PCT/US2000/001484 patent/WO2000044403A1/en not_active Ceased
- 2000-01-20 JP JP2000595705A patent/JP2002534995A/ja active Pending
- 2000-07-31 US US09/630,155 patent/US6414130B1/en not_active Expired - Fee Related
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2008
- 2008-06-30 US US12/165,317 patent/US7939080B2/en not_active Expired - Fee Related
-
2011
- 2011-05-09 US US13/103,888 patent/US20120088255A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090270316A1 (en) | 2009-10-29 |
| EP1144004A4 (en) | 2002-09-04 |
| AU777422B2 (en) | 2004-10-14 |
| US7393823B1 (en) | 2008-07-01 |
| AU4795100A (en) | 2000-08-18 |
| EP1144004A1 (en) | 2001-10-17 |
| US7939080B2 (en) | 2011-05-10 |
| CA2361181A1 (en) | 2000-08-03 |
| US6414130B1 (en) | 2002-07-02 |
| JP2002534995A (ja) | 2002-10-22 |
| WO2000044403A1 (en) | 2000-08-03 |
| US20120088255A1 (en) | 2012-04-12 |
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