JP2002533119A - グリコシルホスファチジルイノシトール特異的ホスホリパーゼｄタンパク質及びその使用 - Google Patents

グリコシルホスファチジルイノシトール特異的ホスホリパーゼｄタンパク質及びその使用

Info

Publication number
JP2002533119A
JP2002533119A JP2000591177A JP2000591177A JP2002533119A JP 2002533119 A JP2002533119 A JP 2002533119A JP 2000591177 A JP2000591177 A JP 2000591177A JP 2000591177 A JP2000591177 A JP 2000591177A JP 2002533119 A JP2002533119 A JP 2002533119A
Authority
JP
Japan
Prior art keywords
pld
gpi
nucleic acid
diabetes
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000591177A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002533119A5 (cg-RX-API-DMAC7.html
Inventor
ジュリアン・ショフィールド
トーマス・ウィリアム・レイドメイチャー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College London
Original Assignee
University College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828715.4A external-priority patent/GB9828715D0/en
Priority claimed from GBGB9828712.1A external-priority patent/GB9828712D0/en
Priority claimed from GBGB9828713.9A external-priority patent/GB9828713D0/en
Application filed by University College London filed Critical University College London
Publication of JP2002533119A publication Critical patent/JP2002533119A/ja
Publication of JP2002533119A5 publication Critical patent/JP2002533119A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2000591177A 1998-12-24 1999-12-23 グリコシルホスファチジルイノシトール特異的ホスホリパーゼｄタンパク質及びその使用 Pending JP2002533119A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9828715.4A GB9828715D0 (en) 1998-12-24 1998-12-24 Glycosylphosphatidylinositol specific phospholipase d protiens and uses thereof
GBGB9828712.1A GB9828712D0 (en) 1998-12-24 1998-12-24 Glycosylphosphatidylinositol specific phospholipase d proteins and usues thereof
GBGB9828713.9A GB9828713D0 (en) 1998-12-24 1998-12-24 Glycosylphosphatidylinositol specific phospholipase d protiens and uses therof
GB9828715.4 1998-12-24
GB9828713.9 1998-12-24
GB9828712.1 1998-12-24
PCT/GB1999/004399 WO2000039285A2 (en) 1998-12-24 1999-12-23 Human glycosylphosphatidylinositol specific phospholipase d variants and uses thereof

Publications (2)

Publication Number Publication Date
JP2002533119A true JP2002533119A (ja) 2002-10-08
JP2002533119A5 JP2002533119A5 (cg-RX-API-DMAC7.html) 2007-02-15

Family

ID=27269604

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000591177A Pending JP2002533119A (ja) 1998-12-24 1999-12-23 グリコシルホスファチジルイノシトール特異的ホスホリパーゼｄタンパク質及びその使用

Country Status (7)

Country Link
EP (1) EP1141334B1 (cg-RX-API-DMAC7.html)
JP (1) JP2002533119A (cg-RX-API-DMAC7.html)
AT (1) ATE410516T1 (cg-RX-API-DMAC7.html)
AU (1) AU774986B2 (cg-RX-API-DMAC7.html)
CA (1) CA2355468A1 (cg-RX-API-DMAC7.html)
DE (1) DE69939707D1 (cg-RX-API-DMAC7.html)
WO (1) WO2000039285A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016515123A (ja) * 2013-03-15 2016-05-26 アムジエン・インコーポレーテツド Ｐｌａ２ｇ１２ａポリペプチド及びｐｌａ２ｇ１２ａ変異ポリペプチドを使用して代謝障害を治療する方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015625D0 (en) * 2000-06-26 2000-08-16 Univ London Materials and methods relating for the treatment and diagnosis of pre-eclampsia
GB0015986D0 (en) * 2000-06-29 2000-08-23 Univ London Glycosylphosphatidylinositol specific phospholipase d proteins or the treatment or diagnosis of atherosclerosis
AU2004251690A1 (en) * 2003-06-04 2005-01-06 Duke University Compositions and methods for modulating S-nitrosoglutathione reductase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0477739A3 (en) * 1990-09-27 1992-12-09 F. Hoffmann-La Roche Ag Glycosyl-phosphatidylinositol-specific phospholipase d
CA2321113A1 (en) * 1998-03-18 1999-09-23 Thomas William Rademacher Anti-inositolphosphoglycan monoclonal antibodies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016515123A (ja) * 2013-03-15 2016-05-26 アムジエン・インコーポレーテツド Ｐｌａ２ｇ１２ａポリペプチド及びｐｌａ２ｇ１２ａ変異ポリペプチドを使用して代謝障害を治療する方法

Also Published As

Publication number Publication date
EP1141334B1 (en) 2008-10-08
ATE410516T1 (de) 2008-10-15
WO2000039285A2 (en) 2000-07-06
DE69939707D1 (de) 2008-11-20
AU1988300A (en) 2000-07-31
CA2355468A1 (en) 2000-07-06
WO2000039285A3 (en) 2000-11-16
EP1141334A2 (en) 2001-10-10
AU774986B2 (en) 2004-07-15

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