AU774986B2 - Glycosyl phosphatidy linositol specific phospholipase D proteins and uses thereof - Google Patents

Glycosyl phosphatidy linositol specific phospholipase D proteins and uses thereof Download PDF

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Publication number
AU774986B2
AU774986B2 AU19883/00A AU1988300A AU774986B2 AU 774986 B2 AU774986 B2 AU 774986B2 AU 19883/00 A AU19883/00 A AU 19883/00A AU 1988300 A AU1988300 A AU 1988300A AU 774986 B2 AU774986 B2 AU 774986B2
Authority
AU
Australia
Prior art keywords
gpi
pld
nucleic acid
diabetes
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU19883/00A
Other languages
English (en)
Other versions
AU1988300A (en
Inventor
Thomas William Rademacher
Julian Schofield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sylus Pharmaceuticals Ltd
Original Assignee
Sylus Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828715.4A external-priority patent/GB9828715D0/en
Priority claimed from GBGB9828712.1A external-priority patent/GB9828712D0/en
Priority claimed from GBGB9828713.9A external-priority patent/GB9828713D0/en
Application filed by Sylus Pharmaceuticals Ltd filed Critical Sylus Pharmaceuticals Ltd
Publication of AU1988300A publication Critical patent/AU1988300A/en
Assigned to SYLUS PHARMACEUTICALS LTD reassignment SYLUS PHARMACEUTICALS LTD Alteration of Name(s) of Applicant(s) under S113 Assignors: UNIVERSITY COLLEGE LONDON
Application granted granted Critical
Publication of AU774986B2 publication Critical patent/AU774986B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU19883/00A 1998-12-24 1999-12-23 Glycosyl phosphatidy linositol specific phospholipase D proteins and uses thereof Ceased AU774986B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9828715.4A GB9828715D0 (en) 1998-12-24 1998-12-24 Glycosylphosphatidylinositol specific phospholipase d protiens and uses thereof
GB9828712 1998-12-24
GBGB9828712.1A GB9828712D0 (en) 1998-12-24 1998-12-24 Glycosylphosphatidylinositol specific phospholipase d proteins and usues thereof
GB9828715 1998-12-24
GBGB9828713.9A GB9828713D0 (en) 1998-12-24 1998-12-24 Glycosylphosphatidylinositol specific phospholipase d protiens and uses therof
GB9828713 1998-12-24
PCT/GB1999/004399 WO2000039285A2 (en) 1998-12-24 1999-12-23 Human glycosylphosphatidylinositol specific phospholipase d variants and uses thereof

Publications (2)

Publication Number Publication Date
AU1988300A AU1988300A (en) 2000-07-31
AU774986B2 true AU774986B2 (en) 2004-07-15

Family

ID=27269604

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19883/00A Ceased AU774986B2 (en) 1998-12-24 1999-12-23 Glycosyl phosphatidy linositol specific phospholipase D proteins and uses thereof

Country Status (7)

Country Link
EP (1) EP1141334B1 (cg-RX-API-DMAC7.html)
JP (1) JP2002533119A (cg-RX-API-DMAC7.html)
AT (1) ATE410516T1 (cg-RX-API-DMAC7.html)
AU (1) AU774986B2 (cg-RX-API-DMAC7.html)
CA (1) CA2355468A1 (cg-RX-API-DMAC7.html)
DE (1) DE69939707D1 (cg-RX-API-DMAC7.html)
WO (1) WO2000039285A2 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015625D0 (en) * 2000-06-26 2000-08-16 Univ London Materials and methods relating for the treatment and diagnosis of pre-eclampsia
GB0015986D0 (en) * 2000-06-29 2000-08-23 Univ London Glycosylphosphatidylinositol specific phospholipase d proteins or the treatment or diagnosis of atherosclerosis
AU2004251690A1 (en) * 2003-06-04 2005-01-06 Duke University Compositions and methods for modulating S-nitrosoglutathione reductase
CA2906540C (en) * 2013-03-15 2021-01-12 Amgen Inc. Method of treating metabolic disorders using pla2g12a polypeptides and pla2g12a mutant polypeptides

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0477739A2 (en) * 1990-09-27 1992-04-01 F. Hoffmann-La Roche Ag Glycosyl-Phosphatidylinositol-Specific Phospholipase D

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2321113A1 (en) * 1998-03-18 1999-09-23 Thomas William Rademacher Anti-inositolphosphoglycan monoclonal antibodies

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0477739A2 (en) * 1990-09-27 1992-04-01 F. Hoffmann-La Roche Ag Glycosyl-Phosphatidylinositol-Specific Phospholipase D

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HOENER AND BRODBECK (SEE ISR) *
SCALLON ET AL. (SEE ISR) *

Also Published As

Publication number Publication date
JP2002533119A (ja) 2002-10-08
EP1141334B1 (en) 2008-10-08
ATE410516T1 (de) 2008-10-15
WO2000039285A2 (en) 2000-07-06
DE69939707D1 (de) 2008-11-20
AU1988300A (en) 2000-07-31
CA2355468A1 (en) 2000-07-06
WO2000039285A3 (en) 2000-11-16
EP1141334A2 (en) 2001-10-10

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: SYLUS PHARMACEUTICALS LTD

Free format text: THE FORMER OWNER WAS: UNIVERSITY COLLEGE LONDON

FGA Letters patent sealed or granted (standard patent)