JP2002531490A - 中枢神経系に薬剤を投与するための方法 - Google Patents

中枢神経系に薬剤を投与するための方法

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Publication number
JP2002531490A
JP2002531490A JP2000586308A JP2000586308A JP2002531490A JP 2002531490 A JP2002531490 A JP 2002531490A JP 2000586308 A JP2000586308 A JP 2000586308A JP 2000586308 A JP2000586308 A JP 2000586308A JP 2002531490 A JP2002531490 A JP 2002531490A
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Prior art keywords
agent
nerve
drug
brain
nervous system
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Pending
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JP2000586308A
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English (en)
Japanese (ja)
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JP2002531490A5 (enExample
Inventor
ウィリアム エイチ. ザ セカンド フレイ,
ロバート ギャリー ソーン,
Original Assignee
カイロン コーポレイション
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Publication of JP2002531490A publication Critical patent/JP2002531490A/ja
Publication of JP2002531490A5 publication Critical patent/JP2002531490A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • AIDS & HIV (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000586308A 1998-12-09 1999-12-09 中枢神経系に薬剤を投与するための方法 Pending JP2002531490A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20853998A 1998-12-09 1998-12-09
US09/208,539 1998-12-09
PCT/US1999/029335 WO2000033814A2 (en) 1998-12-09 1999-12-09 Method for administering agents to the central nervous system

Publications (2)

Publication Number Publication Date
JP2002531490A true JP2002531490A (ja) 2002-09-24
JP2002531490A5 JP2002531490A5 (enExample) 2006-12-14

Family

ID=22774961

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000586308A Pending JP2002531490A (ja) 1998-12-09 1999-12-09 中枢神経系に薬剤を投与するための方法

Country Status (6)

Country Link
EP (1) EP1135105B1 (enExample)
JP (1) JP2002531490A (enExample)
AT (1) ATE289800T1 (enExample)
AU (1) AU2173400A (enExample)
DE (1) DE69923998T2 (enExample)
WO (1) WO2000033814A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009504724A (ja) * 2005-08-19 2009-02-05 アナバシス ソシエテ ア レスポンサビリタ リミタータ アルツハイマー病又はパーキンソン病のような中枢神経系の病態の治療のための、点眼液における神経成長因子の使用
JP2010531810A (ja) * 2007-06-29 2010-09-30 クラレンス ピーティーワイ エルティーディー 点眼投与による神経疾患または精神神経疾患の治療または予防
US9345749B2 (en) 1999-01-29 2016-05-24 Dompé Farmaceutici S.P.A. Method of treating intraoccular tissue pathologies with nerve growth factor
JP2019529397A (ja) * 2016-09-07 2019-10-17 グリア エルエルシーGlia, Llc 脳神経の薬理学的な経皮活性化による神経変性障害に関連する症状の治療
JP2021001173A (ja) * 2014-11-21 2021-01-07 バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッドBiohaven Pharmaceutical Holding Company Ltd. リルゾールの舌下製剤

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EP1602378A1 (en) * 1999-12-09 2005-12-07 Chiron Corporation Method for administering a cytokine to the central nervous system and the lymphatic system
DE60021760T2 (de) * 1999-12-09 2006-06-08 Chiron Corp., Emeryville Verfahren zur verabreichung von wirkstoffen in das zentrale nervensystem oder lymphsystem
US20100160293A1 (en) * 2005-02-17 2010-06-24 Kakuji Tojo Solid Ophthalmic Drug for External Use
US20090136505A1 (en) 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
EP1928484B1 (en) 2005-08-26 2010-02-24 The Board Of Trustees Of The Leland Stanford Junior University Methods for treatment of headaches by administration of oxytocin
US8153604B2 (en) 2006-04-24 2012-04-10 Geron Corporation CNS-tumor treatment method and composition
US8778904B2 (en) 2009-12-09 2014-07-15 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the CNS
US8609088B2 (en) 2011-05-10 2013-12-17 Regents Of The University Of Minnesota Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
WO2012174481A1 (en) 2011-06-15 2012-12-20 Nerve Access, Inc. Pharmaceutical compositions for intranasal administration for the treatment of neurodegenerative disorders
RU2692251C2 (ru) 2013-05-15 2019-06-24 Риджентс Оф Зэ Юниверсити Оф Миннесота Опосредованный аденоассоциированным вирусом перенос генов в центральную нервную систему
PL3865563T3 (pl) 2014-11-25 2024-01-29 Corning Incorporated Materiały i sposoby do przedłużania pożywki do hodowli komórkowej
JP7030517B2 (ja) 2015-01-07 2022-03-07 トライジェミナ, インコーポレイテッド マグネシウム含有オキシトシン製剤および使用の方法
WO2017017543A1 (en) * 2015-07-30 2017-02-02 U R Anoop Drug delivery system and method for controlled and continuous delivery of drugs into the brain by bypassing the blood brain barrier
US11207461B2 (en) 2015-07-30 2021-12-28 Anoop U. R Drug delivery system and method for controlled and continuous delivery of drugs into the brain by bypassing the blood brain barrier
CN115814055A (zh) 2016-04-12 2023-03-21 三叉神经股份公司 含镁催产素制剂和应用方法
WO2017181113A1 (en) 2016-04-15 2017-10-19 The Trustees Of The University Of Pennsyvania Gene therapy for treating mucopolysaccharidosis type ii
TWI835747B (zh) 2017-09-22 2024-03-21 賓州大學委員會 用於治療黏多醣病 ii 型之基因治療

Citations (3)

* Cited by examiner, † Cited by third party
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JPH06510305A (ja) * 1992-04-15 1994-11-17 セファロン,インコーポレイテッド インスリン様成長因子およびアナログの適用による疾患の治療
JPH08231404A (ja) * 1995-01-17 1996-09-10 Birkmayer Usa 経鼻、経舌下、経直腸及び経皮投与のためのnadh及びnadph治療剤
WO1998020891A1 (en) * 1996-11-13 1998-05-22 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth using compounds with affinity for fkbp12 in combination with neurotrophic factors

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WO1986002271A1 (en) * 1984-10-19 1986-04-24 Chiron Corporation Promotion of wound healing with human epidermal growth factor prepared from recombinant dna
JP3191038B2 (ja) * 1996-06-26 2001-07-23 輝夫 西田 眼科用医薬組成物
IT1289608B1 (it) * 1997-02-05 1998-10-15 Angelini Ricerche Spa Composizione per uso terapeutico o diagnostico somministrabile per via intranasale,sublinguale o vaginale

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06510305A (ja) * 1992-04-15 1994-11-17 セファロン,インコーポレイテッド インスリン様成長因子およびアナログの適用による疾患の治療
JPH08231404A (ja) * 1995-01-17 1996-09-10 Birkmayer Usa 経鼻、経舌下、経直腸及び経皮投与のためのnadh及びnadph治療剤
WO1998020891A1 (en) * 1996-11-13 1998-05-22 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth using compounds with affinity for fkbp12 in combination with neurotrophic factors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6010000972, Bengt Andree et al., Psychopharmacology, 1997, Vol.131, p.339−345 *
JPN6010000985, Jacqueline J. Van Ham et al., EXPERIMENTAL NEUROLOGY, 1996, Vol.142, p.217−225 *
JPN6010000989, Joseph G. Motwani et al., Clin.Pharmacokinet., 1991, Vol.21 No.2, p.83−94 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9345749B2 (en) 1999-01-29 2016-05-24 Dompé Farmaceutici S.P.A. Method of treating intraoccular tissue pathologies with nerve growth factor
US9468665B1 (en) 1999-01-29 2016-10-18 Dompé Farmaceutici S.P.A. Method of treating intraoccular tissue pathologies with nerve growth factor
US10010586B2 (en) 1999-01-29 2018-07-03 Dompé Farmaceutici S.P.A. Method of treating intraocular tissue pathologies with nerve growth factor
JP2009504724A (ja) * 2005-08-19 2009-02-05 アナバシス ソシエテ ア レスポンサビリタ リミタータ アルツハイマー病又はパーキンソン病のような中枢神経系の病態の治療のための、点眼液における神経成長因子の使用
JP2010531810A (ja) * 2007-06-29 2010-09-30 クラレンス ピーティーワイ エルティーディー 点眼投与による神経疾患または精神神経疾患の治療または予防
US12042471B2 (en) 2007-06-29 2024-07-23 Photopharmics, Inc. Ocular treatments for neurological and neuropsychiatric disorders
JP2021001173A (ja) * 2014-11-21 2021-01-07 バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッドBiohaven Pharmaceutical Holding Company Ltd. リルゾールの舌下製剤
JP2023065398A (ja) * 2014-11-21 2023-05-12 バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッド リルゾールの舌下製剤
JP2019529397A (ja) * 2016-09-07 2019-10-17 グリア エルエルシーGlia, Llc 脳神経の薬理学的な経皮活性化による神経変性障害に関連する症状の治療
JP7378781B2 (ja) 2016-09-07 2023-11-14 グリア エルエルシー 脳神経の薬理学的な経皮活性化による神経変性障害に関連する症状の治療

Also Published As

Publication number Publication date
DE69923998D1 (de) 2005-04-07
EP1135105B1 (en) 2005-03-02
ATE289800T1 (de) 2005-03-15
AU2173400A (en) 2000-06-26
EP1135105A2 (en) 2001-09-26
WO2000033814A2 (en) 2000-06-15
DE69923998T2 (de) 2006-04-27
WO2000033814A3 (en) 2000-11-30

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