JP2002527401A - Fgfの脈管形成的に有効な単位用量および投与方法 - Google Patents
Fgfの脈管形成的に有効な単位用量および投与方法Info
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- JP2002527401A JP2002527401A JP2000575522A JP2000575522A JP2002527401A JP 2002527401 A JP2002527401 A JP 2002527401A JP 2000575522 A JP2000575522 A JP 2000575522A JP 2000575522 A JP2000575522 A JP 2000575522A JP 2002527401 A JP2002527401 A JP 2002527401A
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- fgf
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- unit dose
- mutein
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US10410398P | 1998-10-13 | 1998-10-13 | |
| US60/104,103 | 1998-10-13 | ||
| PCT/US1999/022936 WO2000021548A2 (en) | 1998-10-13 | 1999-10-13 | Angiogenically effective unit dose of fgf and method of administering |
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| JP2010043385A Division JP2010174017A (ja) | 1998-10-13 | 2010-02-26 | Fgfの脈管形成的に有効な単位用量および投与方法 |
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| JP2002527401A true JP2002527401A (ja) | 2002-08-27 |
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| JP2010043385A Withdrawn JP2010174017A (ja) | 1998-10-13 | 2010-02-26 | Fgfの脈管形成的に有効な単位用量および投与方法 |
| JP2013098522A Pending JP2013155193A (ja) | 1998-10-13 | 2013-05-08 | Fgfの脈管形成的に有効な単位用量および投与方法 |
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| JP2010043385A Withdrawn JP2010174017A (ja) | 1998-10-13 | 2010-02-26 | Fgfの脈管形成的に有効な単位用量および投与方法 |
| JP2013098522A Pending JP2013155193A (ja) | 1998-10-13 | 2013-05-08 | Fgfの脈管形成的に有効な単位用量および投与方法 |
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| US (4) | US6451303B1 (https=) |
| EP (1) | EP1121141A2 (https=) |
| JP (3) | JP2002527401A (https=) |
| AU (1) | AU6411199A (https=) |
| WO (1) | WO2000021548A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003519097A (ja) * | 1999-08-13 | 2003-06-17 | カイロン コーポレイション | 脈管形成因子の用量および心筋血流を改善するための投与方法 |
| JP2014522807A (ja) * | 2011-06-17 | 2014-09-08 | アレス トレーディング ソシエテ アノニム | Fgf−18の凍結乾燥製剤 |
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| US8618052B2 (en) | 1998-10-13 | 2013-12-31 | Novartis Vaccines And Diagnostics, Inc. | Method of treating coronary artery disease by administering FGF-5 |
| US20030166550A1 (en) * | 1999-08-27 | 2003-09-04 | Chiron Corporation | Angiogenically effective unit dose of FGF-2 and method of use |
| JP2002527401A (ja) * | 1998-10-13 | 2002-08-27 | カイロン コーポレイション | Fgfの脈管形成的に有効な単位用量および投与方法 |
| US6992066B2 (en) * | 1998-10-16 | 2006-01-31 | Zimmer Orthobiologics, Inc. | Povidone-containing carriers for polypeptide growth factors |
| US7087577B2 (en) * | 1998-10-16 | 2006-08-08 | Zimmer Orthobiologies, Inc. | Method of promoting natural bypass |
| US20040097996A1 (en) | 1999-10-05 | 2004-05-20 | Omnisonics Medical Technologies, Inc. | Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode |
| US6551337B1 (en) | 1999-10-05 | 2003-04-22 | Omnisonics Medical Technologies, Inc. | Ultrasonic medical device operating in a transverse mode |
| US6524251B2 (en) | 1999-10-05 | 2003-02-25 | Omnisonics Medical Technologies, Inc. | Ultrasonic device for tissue ablation and sheath for use therewith |
| US20020115603A1 (en) | 2000-06-22 | 2002-08-22 | Chiron Corporation | Methods and compositions for the treatment of peripheral artery disease |
| WO2002017956A2 (en) * | 2000-08-31 | 2002-03-07 | Chiron Corporation | Stabilized fgf formulations containing reducing agents |
| WO2002077199A2 (en) * | 2001-03-27 | 2002-10-03 | Massachusetts Institute Of Technology | Methods and products related to fgf dimerization |
| US20030139333A1 (en) * | 2002-01-18 | 2003-07-24 | Genetix Pharmaceuticals, Inc. | Methods and compositions for promoting angiogenesis |
| AU2003279770A1 (en) * | 2002-10-01 | 2004-04-23 | Novartis Vaccines And Diagnostics, Inc. | Anti-cancer and anti-infectious disease compositions and methods for using same |
| CN100579579C (zh) * | 2002-10-01 | 2010-01-13 | 诺华疫苗和诊断公司 | 抗癌及抗感染性疾病组合物及其使用方法 |
| US7195598B2 (en) * | 2003-05-23 | 2007-03-27 | Siemens Aktiengesellschaft | Method for determining the effectiveness of a medical therapy by analysis of collateral vessels |
| US7794414B2 (en) | 2004-02-09 | 2010-09-14 | Emigrant Bank, N.A. | Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes |
| WO2006063132A2 (en) | 2004-12-06 | 2006-06-15 | The Regents Of The University Of California | Methods for improving the structure and function of arterioles |
| WO2006081190A2 (en) * | 2005-01-25 | 2006-08-03 | Five Prime Therapeutics, Inc. | Compositions and methods for treating cardiac conditions |
| US20100303793A1 (en) * | 2007-04-10 | 2010-12-02 | The Board Of Regents, The University Of Texas Syst | Combination therapy for cardiac revascularization and cardiac repair |
| JP2011515471A (ja) * | 2008-03-26 | 2011-05-19 | オーソロジック コーポレイション | 急性心筋梗塞を処置するための方法 |
| EP2310039B1 (en) | 2008-05-02 | 2014-07-16 | University Of Western Ontario | Fgf-9 and its use relating to blood vessels |
| GB0814302D0 (en) | 2008-08-05 | 2008-10-01 | Coretherapix Slu | Compounds and methods |
| US20140045751A1 (en) * | 2012-08-10 | 2014-02-13 | Florida State University Research Foundation | Recombinant human fibroblast growth factor-1 as a novel therapeutic for ischemic diseases and methods thereof |
| CN108693179A (zh) * | 2018-05-17 | 2018-10-23 | 郑州翱翔医药科技股份有限公司 | 一种药用丁基橡胶塞质量的快速鉴定方法 |
| KR102273945B1 (ko) * | 2019-12-31 | 2021-07-06 | 주식회사 알지프로나 | 인간섬유아세포성장인자 타입2 (hFGF2) 생산 발현용 벡터 및 상기 벡터로 형질전환된 미세조류 |
| KR102283915B1 (ko) * | 2019-12-31 | 2021-08-02 | 주식회사 알지프로나 | 인간섬유아세포성장인자 타입1 (hFGF1) 생산 발현용 벡터 및 상기 벡터로 형질전환된 미세조류 |
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| EP0421455B1 (en) * | 1989-10-06 | 1995-04-05 | Takeda Chemical Industries, Ltd. | A mutein of HST-1 and production thereof |
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| US5612211A (en) * | 1990-06-08 | 1997-03-18 | New York University | Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors |
| US5206354A (en) | 1990-11-23 | 1993-04-27 | American Cyanamid Company | Dna sequence encoding active fragment of fibroblast growth factor, hbf-2 |
| ES2087207T3 (es) | 1990-11-23 | 1996-07-16 | American Cyanamid Co | Factor del crecimiento de fibroblasto quimerico. |
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| US5269326A (en) | 1991-10-24 | 1993-12-14 | Georgetown University | Method for transvenously accessing the pericardial space via the right auricle for medical procedures |
| US5244460A (en) | 1991-11-27 | 1993-09-14 | The United States Of America As Represented By The Department Of Health And Human Services | Method to foster myocardial blood vessel growth and improve blood flow to the heart |
| US5491220A (en) | 1993-09-24 | 1996-02-13 | Yeda Research And Development Co., Ltd. | Surface loop structural analogues of fibroblast growth factors |
| US20030148968A1 (en) * | 1995-02-28 | 2003-08-07 | Hammond H. Kirk | Techniques and compositions for treating cardiovascular disease by in vivo gene delivery |
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| JP2000502682A (ja) * | 1995-12-22 | 2000-03-07 | ローカルメッド インコーポレイテッド | 血管新生を促進する成長因子の局所的血管内デリバリー |
| DE69838526T2 (de) * | 1998-02-05 | 2008-07-03 | Biosense Webster, Inc., Diamond Bar | Gerät zum Freisetzen eines Medikaments im Herzen |
| ES2233101T3 (es) | 1998-09-03 | 2005-06-01 | Chiron Corp | Dosis unitaria de fgf-2 angiogenicamente efectiva y su utilizacion. |
| US20030166550A1 (en) * | 1999-08-27 | 2003-09-04 | Chiron Corporation | Angiogenically effective unit dose of FGF-2 and method of use |
| US20020072489A1 (en) * | 1998-10-13 | 2002-06-13 | Whitehouse Martha J. | Angiogenically effective unit dose of FGF-2 and method of use |
| US6440934B1 (en) * | 1998-10-13 | 2002-08-27 | Chiron Corporation | Angiogenically effective unit dose of FGF-2 and method of use |
| JP2002527401A (ja) * | 1998-10-13 | 2002-08-27 | カイロン コーポレイション | Fgfの脈管形成的に有効な単位用量および投与方法 |
-
1999
- 1999-10-13 JP JP2000575522A patent/JP2002527401A/ja not_active Withdrawn
- 1999-10-13 US US09/417,721 patent/US6451303B1/en not_active Expired - Lifetime
- 1999-10-13 EP EP99951728A patent/EP1121141A2/en not_active Withdrawn
- 1999-10-13 WO PCT/US1999/022936 patent/WO2000021548A2/en not_active Ceased
- 1999-10-13 AU AU64111/99A patent/AU6411199A/en not_active Abandoned
-
2002
- 2002-04-25 US US10/131,965 patent/US20020165160A1/en not_active Abandoned
-
2005
- 2005-09-29 US US11/238,936 patent/US7511019B2/en not_active Expired - Fee Related
-
2009
- 2009-02-24 US US12/391,956 patent/US7858584B2/en not_active Expired - Fee Related
-
2010
- 2010-02-26 JP JP2010043385A patent/JP2010174017A/ja not_active Withdrawn
-
2013
- 2013-05-08 JP JP2013098522A patent/JP2013155193A/ja active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003519097A (ja) * | 1999-08-13 | 2003-06-17 | カイロン コーポレイション | 脈管形成因子の用量および心筋血流を改善するための投与方法 |
| JP2016104799A (ja) * | 1999-08-13 | 2016-06-09 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 脈管形成因子の用量および心筋血流を改善するための投与方法 |
| JP2017200945A (ja) * | 1999-08-13 | 2017-11-09 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 脈管形成因子の用量および心筋血流を改善するための投与方法 |
| JP2014522807A (ja) * | 2011-06-17 | 2014-09-08 | アレス トレーディング ソシエテ アノニム | Fgf−18の凍結乾燥製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000021548A3 (en) | 2000-08-31 |
| US6451303B1 (en) | 2002-09-17 |
| US20090170776A1 (en) | 2009-07-02 |
| WO2000021548A2 (en) | 2000-04-20 |
| US7511019B2 (en) | 2009-03-31 |
| JP2013155193A (ja) | 2013-08-15 |
| US7858584B2 (en) | 2010-12-28 |
| JP2010174017A (ja) | 2010-08-12 |
| US20060025343A1 (en) | 2006-02-02 |
| US20020165160A1 (en) | 2002-11-07 |
| AU6411199A (en) | 2000-05-01 |
| EP1121141A2 (en) | 2001-08-08 |
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