JP2002525043A5 - - Google Patents
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- Publication number
- JP2002525043A5 JP2002525043A5 JP2000570292A JP2000570292A JP2002525043A5 JP 2002525043 A5 JP2002525043 A5 JP 2002525043A5 JP 2000570292 A JP2000570292 A JP 2000570292A JP 2000570292 A JP2000570292 A JP 2000570292A JP 2002525043 A5 JP2002525043 A5 JP 2002525043A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- cells
- submucosa
- cell
- primary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000001519 tissue Anatomy 0.000 description 39
- 210000004027 cell Anatomy 0.000 description 31
- 210000004876 tela submucosa Anatomy 0.000 description 27
- 230000000968 intestinal effect Effects 0.000 description 19
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 17
- 210000002919 epithelial cell Anatomy 0.000 description 10
- 239000011159 matrix material Substances 0.000 description 9
- 230000008439 repair process Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 108010035532 Collagen Proteins 0.000 description 7
- 102000008186 Collagen Human genes 0.000 description 7
- 229920001436 collagen Polymers 0.000 description 7
- 238000004113 cell culture Methods 0.000 description 6
- 210000003527 eukaryotic cell Anatomy 0.000 description 6
- 230000010261 cell growth Effects 0.000 description 5
- 210000001612 chondrocyte Anatomy 0.000 description 4
- 239000002131 composite material Substances 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 3
- 230000003239 periodontal effect Effects 0.000 description 3
- 210000003491 skin Anatomy 0.000 description 3
- 210000002460 smooth muscle Anatomy 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- 108010023728 Alloderm Proteins 0.000 description 2
- 206010061762 Chondropathy Diseases 0.000 description 2
- 102000003886 Glycoproteins Human genes 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000002808 connective tissue Anatomy 0.000 description 2
- 210000004748 cultured cell Anatomy 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 210000002889 endothelial cell Anatomy 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 210000003238 esophagus Anatomy 0.000 description 2
- 210000001648 gingival epithelial cell Anatomy 0.000 description 2
- 210000002510 keratinocyte Anatomy 0.000 description 2
- 230000003387 muscular Effects 0.000 description 2
- 210000000963 osteoblast Anatomy 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 102000007469 Actins Human genes 0.000 description 1
- 108010085238 Actins Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 102000001690 Factor VIII Human genes 0.000 description 1
- 108010054218 Factor VIII Proteins 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 101710127721 Membrane protein Proteins 0.000 description 1
- 102000016611 Proteoglycans Human genes 0.000 description 1
- 108010067787 Proteoglycans Proteins 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004413 cardiac myocyte Anatomy 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 239000012598 cell culture matrix Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000011833 dog model Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000003511 endothelial effect Effects 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 229960000301 factor viii Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000012606 in vitro cell culture Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000004153 islets of langerhan Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000002188 osteogenic effect Effects 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 230000007838 tissue remodeling Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15179098A | 1998-09-11 | 1998-09-11 | |
| US09/151,790 | 1998-09-11 | ||
| PCT/US1999/020996 WO2000015765A1 (en) | 1998-09-11 | 1999-09-10 | Enhanced submucosal tissue graft constructs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002525043A JP2002525043A (ja) | 2002-08-13 |
| JP2002525043A5 true JP2002525043A5 (https=) | 2008-07-24 |
Family
ID=22540248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000570292A Pending JP2002525043A (ja) | 1998-09-11 | 1999-09-10 | 改良粘膜下組織グラフト構成物 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1109888A4 (https=) |
| JP (1) | JP2002525043A (https=) |
| AU (1) | AU766719B2 (https=) |
| CA (1) | CA2342589A1 (https=) |
| WO (1) | WO2000015765A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6485723B1 (en) | 1995-02-10 | 2002-11-26 | Purdue Research Foundation | Enhanced submucosal tissue graft constructs |
| US6576265B1 (en) | 1999-12-22 | 2003-06-10 | Acell, Inc. | Tissue regenerative composition, method of making, and method of use thereof |
| DE10026482A1 (de) * | 2000-05-29 | 2001-12-13 | Augustinus Bader | Verfahren zur Herstellung eines bioartifiziellen Transplantats |
| US7163563B2 (en) | 2001-07-16 | 2007-01-16 | Depuy Products, Inc. | Unitary surgical device and method |
| DE10156561A1 (de) | 2001-11-20 | 2003-05-28 | Artiss Gmbh | Bioartifizielles Trachea-Implantat und Verfahren zu seiner Herstellung |
| US6923833B2 (en) | 2002-04-09 | 2005-08-02 | Ray C. Wasielewski | Biologically reabsorbable acetabular constraining components and materials for use with a hip replacement prosthesis and bioreabsorbable materials to augment hip replacement stability and function |
| WO2003092381A1 (en) | 2002-05-02 | 2003-11-13 | Purdue Research Foundation | Vascularization enhanced graft constructs |
| US9492267B2 (en) | 2002-05-02 | 2016-11-15 | Cook Biotech Incorporated | Cell-seeded extracellular matrix grafts |
| CN1665527A (zh) | 2002-05-02 | 2005-09-07 | 普渡研究基金会 | 血管化增强的移植构造物 |
| EP1503652A4 (en) | 2002-05-02 | 2006-02-08 | Purdue Research Foundation | HYBRID GRAFTS WITH IMPROVED VASCULARIZATION |
| CA2530490A1 (en) | 2003-06-25 | 2005-01-13 | Stephen F. Badylak | Conditioned matrix compositions for tissue restoration |
| US7569233B2 (en) | 2004-05-04 | 2009-08-04 | Depuy Products, Inc. | Hybrid biologic-synthetic bioabsorbable scaffolds |
| US7354627B2 (en) | 2004-12-22 | 2008-04-08 | Depuy Products, Inc. | Method for organizing the assembly of collagen fibers and compositions formed therefrom |
| US7595062B2 (en) | 2005-07-28 | 2009-09-29 | Depuy Products, Inc. | Joint resurfacing orthopaedic implant and associated method |
| US8298586B2 (en) | 2009-07-22 | 2012-10-30 | Acell Inc | Variable density tissue graft composition |
| US8652500B2 (en) | 2009-07-22 | 2014-02-18 | Acell, Inc. | Particulate tissue graft with components of differing density and methods of making and using the same |
| US9878071B2 (en) | 2013-10-16 | 2018-01-30 | Purdue Research Foundation | Collagen compositions and methods of use |
| EP3185922B1 (en) | 2014-08-27 | 2025-04-02 | Purdue Research Foundation | Collagen-based therapeutic delivery systems |
| US11919941B2 (en) | 2015-04-21 | 2024-03-05 | Purdue Research Foundation | Cell-collagen-silica composites and methods of making and using the same |
| CA3052266A1 (en) | 2017-01-31 | 2018-08-09 | Geniphys, Llc | Methods and compositions for matrix preparation |
| US11739291B2 (en) | 2017-04-25 | 2023-08-29 | Purdue Research Foundation | 3-dimensional (3D) tissue-engineered muscle for tissue restoration |
| KR20210005942A (ko) | 2018-05-03 | 2021-01-15 | 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | Il-33을 포함하는 매트릭스 결합 소포 (mbvs) 및 그 용도 |
| EP4096635A4 (en) | 2020-01-27 | 2024-02-21 | GeniPhys, Inc. | BIOLOGICAL FILLER FOR TISSUE RESTORATION AND REGENERATION |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5695998A (en) * | 1995-02-10 | 1997-12-09 | Purdue Research Foundation | Submucosa as a growth substrate for islet cells |
| WO1997017038A1 (en) * | 1995-11-09 | 1997-05-15 | University Of Massachusetts | Tissue re-surfacing with hydrogel-cell compositions |
-
1999
- 1999-09-10 WO PCT/US1999/020996 patent/WO2000015765A1/en not_active Ceased
- 1999-09-10 AU AU58224/99A patent/AU766719B2/en not_active Expired
- 1999-09-10 CA CA002342589A patent/CA2342589A1/en not_active Abandoned
- 1999-09-10 EP EP99945660A patent/EP1109888A4/en not_active Withdrawn
- 1999-09-10 JP JP2000570292A patent/JP2002525043A/ja active Pending
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