JP2002523112A - 毒物学的反応マーカー - Google Patents

毒物学的反応マーカー

Info

Publication number
JP2002523112A
JP2002523112A JP2000567743A JP2000567743A JP2002523112A JP 2002523112 A JP2002523112 A JP 2002523112A JP 2000567743 A JP2000567743 A JP 2000567743A JP 2000567743 A JP2000567743 A JP 2000567743A JP 2002523112 A JP2002523112 A JP 2002523112A
Authority
JP
Japan
Prior art keywords
nucleic acid
molecule
acid molecule
sample
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000567743A
Other languages
English (en)
Japanese (ja)
Inventor
カニンガム、メアリー・ジェーン
ゼイガー、ゲーリー・ビー
パンザー、スコット・アール
サイルハマー、ジェフリー・ジェイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/141,825 external-priority patent/US6403778B1/en
Priority claimed from US09/172,711 external-priority patent/US6160105A/en
Priority claimed from US09/172,108 external-priority patent/US6160104A/en
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Publication of JP2002523112A publication Critical patent/JP2002523112A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000567743A 1998-08-28 1999-08-27 毒物学的反応マーカー Pending JP2002523112A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/141,825 US6403778B1 (en) 1998-05-04 1998-08-28 Toxicological response markers
US09/172,711 US6160105A (en) 1998-10-13 1998-10-13 Monitoring toxicological responses
US09/141,825 1998-10-13
US09/172,711 1998-10-13
US09/172,108 1998-10-13
US09/172,108 US6160104A (en) 1998-10-13 1998-10-13 Markers for peroxisomal proliferators
PCT/US1999/019768 WO2000012760A2 (en) 1998-08-28 1999-08-27 Toxicological response markers

Publications (1)

Publication Number Publication Date
JP2002523112A true JP2002523112A (ja) 2002-07-30

Family

ID=27385714

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000567743A Pending JP2002523112A (ja) 1998-08-28 1999-08-27 毒物学的反応マーカー

Country Status (5)

Country Link
EP (1) EP1108067A2 (de)
JP (1) JP2002523112A (de)
AU (1) AU6022299A (de)
CA (1) CA2340589A1 (de)
WO (1) WO2000012760A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6881571B1 (en) 1998-03-11 2005-04-19 Exonhit Therapeutics S.A. Qualitative differential screening
FR2798392B1 (fr) * 1999-09-13 2005-07-15 Exonhit Therapeutics Sa Marqueurs genetiques de la toxicite, preparation et utilisations
EP1409718A2 (de) * 2000-07-21 2004-04-21 Phase-1 Molecular Toxicology Hundegene im zusammenhang mit toxizität
WO2002010453A2 (en) * 2000-07-31 2002-02-07 Gene Logic, Inc. Molecular toxicology modeling
US7590493B2 (en) 2000-07-31 2009-09-15 Ocimum Biosolutions, Inc. Methods for determining hepatotoxins
EP1368499A2 (de) * 2001-01-29 2003-12-10 Phase-1 Molecular Toxicology Inc. Toxikologisch relevante gene der ratte und deren verwendung
WO2002095000A2 (en) 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
US20040241690A1 (en) * 2001-08-03 2004-12-02 Takayuki Souka Method of evaluating biocompatibility
EP1921157B1 (de) * 2001-08-24 2010-05-26 Daikin Industries, Ltd. Verfahren zum Nachweis toxischer Substanzen
US7469185B2 (en) 2002-02-04 2008-12-23 Ocimum Biosolutions, Inc. Primary rat hepatocyte toxicity modeling
EP1344834A3 (de) * 2002-03-14 2004-06-02 F. Hoffmann-La Roche Ag Verfahren zur Voraussage der Toxizität einer Verbindung
GB0215509D0 (en) * 2002-07-04 2002-08-14 Novartis Ag Marker genes
WO2004058957A2 (en) * 2002-12-31 2004-07-15 Pharmacia & Upjohn Company Llc Canine cyp1a2 sequences

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6114114A (en) * 1992-07-17 2000-09-05 Incyte Pharmaceuticals, Inc. Comparative gene transcript analysis
WO1997013877A1 (en) * 1995-10-12 1997-04-17 Lynx Therapeutics, Inc. Measurement of gene expression profiles in toxicity determination

Also Published As

Publication number Publication date
EP1108067A2 (de) 2001-06-20
AU6022299A (en) 2000-03-21
WO2000012760A2 (en) 2000-03-09
CA2340589A1 (en) 2000-03-09
WO2000012760A3 (en) 2000-08-03

Similar Documents

Publication Publication Date Title
EP1235933A2 (de) Saugtiermarker einer toxicologischen antwort
US6160105A (en) Monitoring toxicological responses
US6709855B1 (en) Methods for detection and use of differentially expressed genes in disease states
EP0991770B1 (de) Prostatakrebs-gen
US20020165345A1 (en) Prostate cancer gene
WO2002068579A2 (en) Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
JP2002523112A (ja) 毒物学的反応マーカー
JP2004532602A (ja) 泡沫細胞分化において発現される遺伝子
JP2003245072A (ja) シグナル伝達経路の決定
US6403778B1 (en) Toxicological response markers
JP2004507206A (ja) 診断上重要な組織特異的遺伝子
US6368794B1 (en) Detection of altered expression of genes regulating cell proliferation
US20030166555A1 (en) Methods and compositions for regulating memory consolidation
JP2004516815A (ja) ダウン症候群重要領域１−様１タンパク質
JP2013176383A (ja) 遺伝子発現解析ツール
JP5301281B2 (ja) 臓器特異的遺伝子、その同定方法およびその用途
US20030165854A1 (en) Marker genes responding to treatment with toxins
US6160104A (en) Markers for peroxisomal proliferators
US7091033B2 (en) Array of toxicologically relevant canine genes and uses thereof
WO2001074298A2 (en) Methods and compositions for regulating memory consolidation
US20020119460A1 (en) Prostate cancer gene
JP2005515757A (ja) ミトコンドリア生物学発現アレイ
US20030207284A1 (en) Haplotypes of the UCP2 gene
EP1052292B1 (de) Prostatakrebs-Gen
US20030198969A1 (en) Haplotypes of the TACR2 gene