JP2002521468A5 - - Google Patents
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- Publication number
- JP2002521468A5 JP2002521468A5 JP2000562338A JP2000562338A JP2002521468A5 JP 2002521468 A5 JP2002521468 A5 JP 2002521468A5 JP 2000562338 A JP2000562338 A JP 2000562338A JP 2000562338 A JP2000562338 A JP 2000562338A JP 2002521468 A5 JP2002521468 A5 JP 2002521468A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- pharmaceutical composition
- embedded image
- composition according
- nitrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 5
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 4
- 229910002651 NO3 Inorganic materials 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 229960001803 cetirizine Drugs 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 229960000325 emedastine Drugs 0.000 description 1
- 229960003088 loratadine Drugs 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 229960000351 terfenadine Drugs 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI001743A IT1303671B1 (it) | 1998-07-28 | 1998-07-28 | Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio |
| IT98A001743 | 1998-07-28 | ||
| PCT/EP1999/005171 WO2000006531A2 (en) | 1998-07-28 | 1999-07-20 | Nitric esters and nitrate salts of specific drugs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002521468A JP2002521468A (ja) | 2002-07-16 |
| JP2002521468A5 true JP2002521468A5 (https=) | 2006-08-31 |
| JP4455760B2 JP4455760B2 (ja) | 2010-04-21 |
Family
ID=11380535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000562338A Expired - Fee Related JP4455760B2 (ja) | 1998-07-28 | 1999-07-20 | 特定の薬物の硝酸エステル及び硝酸塩 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US6410791B1 (https=) |
| EP (1) | EP1098870B1 (https=) |
| JP (1) | JP4455760B2 (https=) |
| KR (1) | KR100687806B1 (https=) |
| CN (1) | CN1264828C (https=) |
| AT (1) | ATE307796T1 (https=) |
| AU (2) | AU770313C (https=) |
| BR (1) | BR9912375A (https=) |
| CA (1) | CA2338854C (https=) |
| DE (1) | DE69927977T2 (https=) |
| DK (1) | DK1098870T3 (https=) |
| ES (1) | ES2252958T3 (https=) |
| HU (1) | HUP0102706A3 (https=) |
| IL (1) | IL140685A0 (https=) |
| IT (1) | IT1303671B1 (https=) |
| RU (1) | RU2254330C2 (https=) |
| WO (1) | WO2000006531A2 (https=) |
| ZA (1) | ZA200100457B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824669A (en) | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| IT1303671B1 (it) * | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio |
| IT1317735B1 (it) * | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
| CA2405918A1 (en) * | 2001-10-01 | 2003-04-01 | Ind-Swift Limited | Controlled release macrolide pharmaceutical formulations |
| CA2487414A1 (en) | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| JP2005535642A (ja) * | 2002-06-28 | 2005-11-24 | ニトロメッド インコーポレーティッド | オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法 |
| GB0406069D0 (en) * | 2004-03-17 | 2004-04-21 | Thompson James | Process |
| WO2006138212A1 (en) * | 2005-06-14 | 2006-12-28 | Gilead Sciences, Inc. | SUBSTITUTED PHENYLPHOSPHATES AS MUTUAL PRODRUGS OF STEROIDS AND β -AGONISTS FOR THE TREATMENT OF PULMONARY INFLAMMATION AND BRONCHOCONSTRICTION |
| TW200804241A (en) * | 2006-02-24 | 2008-01-16 | Novartis Ag | New salt |
| JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
| WO2009142772A2 (en) | 2008-05-23 | 2009-11-26 | Mastcell Pharmaceuticals, Inc. | Methods and treatment for allergies and inflammation associated with gastrointestinal diseases |
| US8513259B2 (en) | 2009-07-03 | 2013-08-20 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| JP6042197B2 (ja) * | 2012-12-11 | 2016-12-14 | エア・ウォーター株式会社 | 肺障害治療剤 |
| CN104211605B (zh) * | 2014-08-18 | 2016-04-27 | 江苏正大清江制药有限公司 | 一种氨溴索与间羟基苯甲酸共晶及其制备方法 |
| CN104211604B (zh) * | 2014-08-18 | 2016-05-11 | 江苏正大清江制药有限公司 | 一种氨溴索与对羟基苯甲酸的共晶及其制备方法 |
| WO2018089797A1 (en) | 2016-11-14 | 2018-05-17 | Mingwu Wang | Formulations for the treatment of ocular surface diseases and related methods |
| CN117304109A (zh) * | 2023-09-14 | 2023-12-29 | 广州医科大学附属市八医院 | 右美沙芬硝酸酯类化合物及其在制备具有预防和/或治疗血管性痴呆作用的药物中的应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2944061A (en) * | 1957-09-20 | 1960-07-05 | Acyl derivatives and process | |
| GB865750A (en) * | 1958-09-26 | 1961-04-19 | American Cyanamid Co | Spiro-phosphonium salts |
| NL125434C (https=) * | 1961-11-20 | 1900-01-01 | ||
| JPS56113748A (en) * | 1980-02-13 | 1981-09-07 | Kowa Co | Aminoethanol derivative and its preparation |
| DE3124410A1 (de) * | 1981-06-22 | 1983-01-05 | Heinrich Mack Nachf., 7918 Illertissen | Verfahren zur herstellung von isosorbid-2-nitrat |
| US4996061A (en) * | 1987-10-07 | 1991-02-26 | Merrell Dow Pharmaceuticals Inc. | Pharmaceutical composition for piperidinoalkanol-decongestant combination |
| GB9001019D0 (en) * | 1990-01-17 | 1990-03-14 | Euro Celtique Sa | Pharmaceutical aerosol |
| US5429825A (en) * | 1992-06-26 | 1995-07-04 | Mcneil-Ppc, Inc. | Rotomelt granulation |
| TW401300B (en) * | 1992-12-25 | 2000-08-11 | Senju Pharma Co | Antiallergic composition for ophthalmic or nasal use |
| WO1995007103A1 (en) | 1993-09-07 | 1995-03-16 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| US5458879A (en) * | 1994-03-03 | 1995-10-17 | The Procter & Gamble Company | Oral vehicle compositions |
| JP3981151B2 (ja) * | 1994-03-28 | 2007-09-26 | ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク | 液体中の刺激物を不活化するための組成物 |
| WO1995030641A1 (en) | 1994-05-10 | 1995-11-16 | Nicox S.A. | Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities |
| US6245350B1 (en) * | 1994-12-16 | 2001-06-12 | Warner-Lambert Company | Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process |
| US6469009B1 (en) * | 1996-04-08 | 2002-10-22 | Ucb, S.A. | Pharmaceutical compositions for the treatment of rhinitis |
| EP0811374A1 (en) * | 1996-05-29 | 1997-12-10 | Pfizer Inc. | Combination dosage form comprising cetirizine and pseudoephedrine |
| WO1998000159A1 (en) | 1996-06-28 | 1998-01-08 | Oxigene, Inc. | Useful formulations of acid addition salt drugs |
| CO4910128A1 (es) * | 1996-10-31 | 2000-04-24 | Schering Corp | Tratamiento del asma y compuestos utiles para este trata- miento ta combinacion y un kit de esta combinacion |
| DE19721467A1 (de) * | 1997-05-22 | 1998-11-26 | Basf Ag | Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe |
| IN188720B (https=) * | 1997-11-06 | 2002-11-02 | Panacea Biotec Ltd | |
| DK1041990T3 (da) | 1997-12-23 | 2006-10-02 | Schering Corp | Præparat til behandling af respiratoriske sygdomme og hudsygdomme med mindst en leukotrien-antagonist og mindst et antihistamin |
| IT1303671B1 (it) * | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio |
| IT1308633B1 (it) * | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
| US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| IT1311923B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| IT1311924B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| IT1317735B1 (it) * | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
| US20020137764A1 (en) * | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
| US6479692B1 (en) * | 2001-05-02 | 2002-11-12 | Nobex Corporation | Methods of synthesizing acylanilides including bicalutamide and derivatives thereof |
| ITMI20021392A1 (it) * | 2002-06-25 | 2003-12-29 | Nicox Sa | Forme farmaceutiche per la somministrazione orale di farmaci liquidi a temperatura ambiente dotate di migliore biodisponibilita' |
-
1998
- 1998-07-28 IT IT1998MI001743A patent/IT1303671B1/it active
-
1999
- 1999-07-20 JP JP2000562338A patent/JP4455760B2/ja not_active Expired - Fee Related
- 1999-07-20 ES ES99938300T patent/ES2252958T3/es not_active Expired - Lifetime
- 1999-07-20 RU RU2001102262/04A patent/RU2254330C2/ru not_active IP Right Cessation
- 1999-07-20 DK DK99938300T patent/DK1098870T3/da active
- 1999-07-20 IL IL14068599A patent/IL140685A0/xx not_active IP Right Cessation
- 1999-07-20 KR KR1020017000803A patent/KR100687806B1/ko not_active Expired - Fee Related
- 1999-07-20 US US09/743,808 patent/US6410791B1/en not_active Expired - Fee Related
- 1999-07-20 HU HU0102706A patent/HUP0102706A3/hu unknown
- 1999-07-20 WO PCT/EP1999/005171 patent/WO2000006531A2/en not_active Ceased
- 1999-07-20 EP EP99938300A patent/EP1098870B1/en not_active Expired - Lifetime
- 1999-07-20 BR BR9912375-4A patent/BR9912375A/pt not_active Application Discontinuation
- 1999-07-20 CN CNB998090425A patent/CN1264828C/zh not_active Expired - Fee Related
- 1999-07-20 CA CA2338854A patent/CA2338854C/en not_active Expired - Fee Related
- 1999-07-20 DE DE69927977T patent/DE69927977T2/de not_active Expired - Lifetime
- 1999-07-20 AU AU52857/99A patent/AU770313C/en not_active Ceased
- 1999-07-20 AT AT99938300T patent/ATE307796T1/de active
-
2001
- 2001-01-16 ZA ZA200100457A patent/ZA200100457B/en unknown
-
2002
- 2002-05-22 US US10/151,955 patent/US6828342B2/en not_active Expired - Fee Related
-
2003
- 2003-12-17 US US10/736,688 patent/US7122539B2/en not_active Expired - Fee Related
-
2004
- 2004-04-07 AU AU2004201457A patent/AU2004201457A1/en not_active Abandoned
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