JP2002518473A - 安定なｎｏ−送達化合物 - Google Patents

安定なｎｏ−送達化合物

Info

Publication number
JP2002518473A
JP2002518473A JP2000555864A JP2000555864A JP2002518473A JP 2002518473 A JP2002518473 A JP 2002518473A JP 2000555864 A JP2000555864 A JP 2000555864A JP 2000555864 A JP2000555864 A JP 2000555864A JP 2002518473 A JP2002518473 A JP 2002518473A
Authority
JP
Japan
Prior art keywords
compound
group
medical device
releasing
polythiol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000555864A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002518473A5 (https=
Inventor
トゥーン，エリック，ジェイ．
スタムラー，ジョナサン，エス．
Original Assignee
デューク ユニバーシティ メディカル センター
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by デューク ユニバーシティ メディカル センター filed Critical デューク ユニバーシティ メディカル センター
Publication of JP2002518473A publication Critical patent/JP2002518473A/ja
Publication of JP2002518473A5 publication Critical patent/JP2002518473A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/23—Solid materials, e.g. granules, powders, blocks or tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/114—Nitric oxide, i.e. NO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Prostheses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000555864A 1998-06-23 1999-06-21 安定なｎｏ−送達化合物 Pending JP2002518473A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/103,227 US6207855B1 (en) 1998-06-23 1998-06-23 Stable no-delivering compounds
US09/103,227 1998-06-23
PCT/US1999/013963 WO1999067210A1 (en) 1998-06-23 1999-06-21 Stable no-delivering compounds

Publications (2)

Publication Number Publication Date
JP2002518473A true JP2002518473A (ja) 2002-06-25
JP2002518473A5 JP2002518473A5 (https=) 2006-08-10

Family

ID=22294054

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000555864A Pending JP2002518473A (ja) 1998-06-23 1999-06-21 安定なｎｏ−送達化合物

Country Status (7)

Country Link
US (6) US6207855B1 (https=)
EP (1) EP1089969B1 (https=)
JP (1) JP2002518473A (https=)
AU (1) AU4580599A (https=)
CA (1) CA2335989A1 (https=)
DE (1) DE69942338D1 (https=)
WO (1) WO1999067210A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011521908A (ja) * 2008-05-09 2011-07-28 デューク ユニバーシティ チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法

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US6207855B1 (en) 1998-06-23 2001-03-27 Duke University Medical Center Stable no-delivering compounds
TWI243672B (en) * 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
CA2403818A1 (en) * 2000-03-20 2001-09-27 Novovascular, Inc. Matrices containing nitric oxide donors and reducing agents and their use
WO2003026717A1 (en) * 2001-09-26 2003-04-03 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Nitric oxide-releasing coated medical devices and method of preparing same
EP1545798A4 (en) * 2002-08-02 2006-06-14 Us Gov Health & Human Serv NETWORKED NITROGEN OXIDE RELEASING POLYAMINE-COATED SUBSTRATES, THESE COMPOSITIONS AND MANUFACTURING PROCESSES DAF R
US8017074B2 (en) * 2004-01-07 2011-09-13 Noxilizer, Inc. Sterilization system and device
EP1701747B1 (en) 2004-01-07 2014-03-12 Noxilizer, Inc. Sterilisation method
US7569559B2 (en) * 2004-02-09 2009-08-04 Noxilizer, Inc. Nitric oxide-releasing molecules
EP1750782A1 (en) * 2004-04-29 2007-02-14 Cube Medical A/S A balloon for use in angioplasty with an outer layer of nanofibers
US7968575B2 (en) * 2004-05-05 2011-06-28 Renopharm Ltd. Nitric oxide donors and uses thereof
US8134010B2 (en) * 2004-05-05 2012-03-13 Renopharm Ltd. Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof
GB0419416D0 (en) * 2004-09-01 2004-10-06 Inst Of Ex Botany Ascr 4-Arylazo-3,5-Diamino-Pyrazole compounds and use thereof
DE102004043279A1 (de) * 2004-09-08 2006-03-23 Theo Woike Verfahren und Vorrichtung zum biologischen, medizinischen und pharmazeutischen Gebrauch des Nitrosylmoleküls NO durch optische Anregung von metastabilen Zuständen in Nitrosylkomplexen
ES2731298T3 (es) 2005-05-27 2019-11-14 Univ North Carolina Chapel Hill Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas
US7968533B2 (en) * 2006-03-07 2011-06-28 Duke University Ethyl nitrite as a gastrointestinal smooth muscle relaxant and diagnostic and therapeutic uses thereof
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US7875671B2 (en) 2006-08-03 2011-01-25 Bridgestone Corporation Process for preparing filler-dispersed polymeric compositions
US8063165B2 (en) 2007-06-18 2011-11-22 Bridgestone Corporation Functional polymers prepared with sulfur-containing initiators
WO2009050527A1 (en) 2007-10-17 2009-04-23 Biotech Hungary Kutató És Fejlesztési Kft. Pharmaceutical composition comprising s-nitrosoglutathione and polysaccharide
US7910574B2 (en) * 2007-12-11 2011-03-22 Illinois State University Treatments for the control of schistosomiasis
US20090170933A1 (en) * 2007-12-26 2009-07-02 Cook Incorporated Method for removing a medical device from a spasmodic constriction in a bodily passageway
EP2334279A4 (en) * 2008-10-16 2013-03-20 Novan Inc STAIN OXIDE RELEASING PARTICLES FOR MOUTH CARE APPLICATIONS
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US9849276B2 (en) 2011-07-12 2017-12-26 Pursuit Vascular, Inc. Method of delivering antimicrobial to a catheter
WO2010096766A1 (en) 2009-02-23 2010-08-26 Noxilizer, Inc. Device and method for gas sterilization
US8137396B2 (en) 2009-05-20 2012-03-20 480 Biomedical, Inc Medical implant
US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
US9309347B2 (en) 2009-05-20 2016-04-12 Biomedical, Inc. Bioresorbable thermoset polyester/urethane elastomers
US20110319987A1 (en) 2009-05-20 2011-12-29 Arsenal Medical Medical implant
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
CA2771389C (en) 2009-08-21 2019-04-09 Novan, Inc. Wound dressings, methods of using the same and methods of forming the same
US8372133B2 (en) 2009-10-05 2013-02-12 480 Biomedical, Inc. Polymeric implant delivery system
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KR101830872B1 (ko) 2009-12-22 2018-02-26 가부시키가이샤 브리지스톤 개선된 비닐 개질제 조성물 및 그러한 조성물의 이용 방법
WO2011082098A1 (en) 2009-12-30 2011-07-07 The Rockefeller University Lysine and arginine methyltransferase inhibitors for treating cancer
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
BR112013016433B1 (pt) 2010-12-30 2021-02-23 Bridgestone Corporation processo para produzir polímeros funcionalizados com aminosilano, polímero telequélico produzido a partir deste processo e composição de borracha para uso em pneus
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
TWI585115B (zh) 2011-12-15 2017-06-01 普利司通股份有限公司 經穩定之多價陰離子聚合反應引發劑及其製備方法
JP6334514B2 (ja) 2012-05-01 2018-05-30 株式会社ブリヂストン オルガノホスフィン官能基を有するポリジエンおよびジエンコポリマー
JP2017501289A (ja) 2013-12-12 2017-01-12 ファイアストン ポリマーズ エルエルシー 官能化ポリマーを含むポリマー組成物の製造方法
ES2755352T3 (es) 2014-05-02 2020-04-22 Excelsior Medical Corp Paquete en tira para tapón antiséptico
DK3294404T3 (da) 2015-05-08 2025-09-08 Icu Medical Inc Medicinske konnektorer konfigureret til at modtage emittere af terapeutiske midler
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WO2018067838A1 (en) * 2016-10-07 2018-04-12 The University Of North Carolina At Chapel Hill S-nitrosothiol-mediated hyperbranched polyesters
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WO2018127819A1 (en) 2017-01-03 2018-07-12 The University Of North Carolina At Chapel Hill Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto
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CN113383019B (zh) 2018-12-28 2023-11-17 北卡罗来纳大学教堂山分校 一氧化氮释放型抗菌聚合物和由其制成的支架和其相关方法
JP2024500319A (ja) 2020-12-07 2024-01-09 アイシーユー・メディカル・インコーポレーテッド 腹膜透析キャップ、システム、及び方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011521908A (ja) * 2008-05-09 2011-07-28 デューク ユニバーシティ チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法

Also Published As

Publication number Publication date
US7745656B2 (en) 2010-06-29
US20040019105A1 (en) 2004-01-29
CA2335989A1 (en) 1999-12-29
AU4580599A (en) 2000-01-10
US20030096862A1 (en) 2003-05-22
US20010000039A1 (en) 2001-03-15
EP1089969A1 (en) 2001-04-11
US6488951B2 (en) 2002-12-03
US6359167B2 (en) 2002-03-19
EP1089969B1 (en) 2010-05-05
DE69942338D1 (de) 2010-06-17
US20060217439A1 (en) 2006-09-28
US6583311B2 (en) 2003-06-24
US20020099330A1 (en) 2002-07-25
WO1999067210A1 (en) 1999-12-29
US7015347B2 (en) 2006-03-21
US6207855B1 (en) 2001-03-27

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