JP2002518346A - Hla結合ペプチドおよびそれらの用途 - Google Patents

Hla結合ペプチドおよびそれらの用途

Info

Publication number
JP2002518346A
JP2002518346A JP2000554400A JP2000554400A JP2002518346A JP 2002518346 A JP2002518346 A JP 2002518346A JP 2000554400 A JP2000554400 A JP 2000554400A JP 2000554400 A JP2000554400 A JP 2000554400A JP 2002518346 A JP2002518346 A JP 2002518346A
Authority
JP
Japan
Prior art keywords
peptide
peptides
cells
mhc
ctl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000554400A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002518346A5 (enExample
Inventor
アレッサンドロ セッテ,
ジョン シドニー,
スコット サウスウッド,
Original Assignee
エピミューン, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エピミューン, インコーポレイテッド filed Critical エピミューン, インコーポレイテッド
Publication of JP2002518346A publication Critical patent/JP2002518346A/ja
Publication of JP2002518346A5 publication Critical patent/JP2002518346A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000554400A 1998-06-17 1999-06-17 Hla結合ペプチドおよびそれらの用途 Pending JP2002518346A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9858498A 1998-06-17 1998-06-17
US09/098,584 1998-06-17
PCT/US1999/013789 WO1999065522A1 (en) 1998-06-17 1999-06-17 Hla binding peptides and their uses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010004446A Division JP2010090167A (ja) 1998-06-17 2010-01-12 Hla結合ペプチドおよびそれらの用途

Publications (2)

Publication Number Publication Date
JP2002518346A true JP2002518346A (ja) 2002-06-25
JP2002518346A5 JP2002518346A5 (enExample) 2006-08-10

Family

ID=22269985

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000554400A Pending JP2002518346A (ja) 1998-06-17 1999-06-17 Hla結合ペプチドおよびそれらの用途
JP2010004446A Pending JP2010090167A (ja) 1998-06-17 2010-01-12 Hla結合ペプチドおよびそれらの用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010004446A Pending JP2010090167A (ja) 1998-06-17 2010-01-12 Hla結合ペプチドおよびそれらの用途

Country Status (8)

Country Link
EP (2) EP1089757B1 (enExample)
JP (2) JP2002518346A (enExample)
AT (1) ATE429247T1 (enExample)
AU (1) AU4577899A (enExample)
CA (1) CA2330824A1 (enExample)
DE (1) DE69940774D1 (enExample)
ES (1) ES2326146T3 (enExample)
WO (1) WO1999065522A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536522A (ja) * 2004-05-07 2007-12-13 ベックマン コールター インコーポレーティッド Ctlの媒介による抗原提示細胞の溶解を検出するためのmhc架橋系

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340577B2 (en) 1992-08-07 2016-05-17 Epimmune Inc. HLA binding motifs and peptides and their uses
DE19925199A1 (de) 1999-06-01 2000-12-07 Medigene Ag Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie
DE19925235A1 (de) 1999-06-01 2000-12-07 Medigene Ag Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie
GB9923309D0 (en) * 1999-10-01 1999-12-08 Glaxo Group Ltd Assay
EP1237564A4 (en) * 1999-12-10 2005-05-04 Epimmune Inc TRIGGERING OF CELLULAR IMMUNE RESPONSES AGAINST P53 USING NUCLEIC ACID AND PEPTIDE COMPOSITIONS
US7462354B2 (en) 1999-12-28 2008-12-09 Pharmexa Inc. Method and system for optimizing minigenes and peptides encoded thereby
EP2391635B1 (en) 2009-01-28 2017-04-26 Epimmune Inc. Pan-dr binding polypeptides and uses thereof
CA2919835A1 (en) 2013-07-31 2015-02-05 Board Of Trustees Of The University Of Arkansas Compositions for and methods of treating and preventing cancer targeting tumor associated carbohydrate antigens

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003205A1 (en) * 1992-08-07 1994-02-17 Cytel Corporation Hla binding peptides and their uses
WO1996018409A1 (en) * 1994-12-14 1996-06-20 The Scripps Research Institute In vivo activation of tumor-specific cytotoxic t cells
JPH08507525A (ja) * 1993-03-05 1996-08-13 サイテル コーポレイション Hla−a2.1結合ペプチドおよびそれらの使用
WO1997041440A1 (en) * 1996-04-26 1997-11-06 Rijksuniversiteit Te Leiden Methods for selecting and producing t cell peptide epitopes and vaccines incorporating said selected epitopes

Family Cites Families (18)

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4690915A (en) 1985-08-08 1987-09-01 The United States Of America As Represented By The Department Of Health And Human Services Adoptive immunotherapy as a treatment modality in humans
US4844893A (en) 1986-10-07 1989-07-04 Scripps Clinic And Research Foundation EX vivo effector cell activation for target cell killing
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
DE69031305T2 (de) 1989-11-03 1998-03-26 Univ Vanderbilt Verfahren zur in vivo-verabreichung von funktionsfähigen fremden genen
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5972351A (en) * 1992-04-03 1999-10-26 Isis Innovation Limited Plasmodium falciparum MHC class I-restricted CTL epitopes derived from pre-erythrocytic stage antigens
ES2139012T3 (es) * 1992-05-26 2000-02-01 Univ Leiden Peptidos de la proteina p53 humana destinados para ser utilizados en composiciones que inducen una reaccion en los linfocitos t humanos, y linfocitos t citotoxicos especificos de la proteina p53 humana.
AU4528493A (en) 1992-06-04 1994-01-04 Regents Of The University Of California, The In vivo gene therapy with intron-free sequence of interest
EP0735893B1 (en) 1993-09-14 2008-11-26 Pharmexa Inc. Pan dr-binding peptides for enhancement of the immune response
US5686068A (en) * 1994-03-24 1997-11-11 Ludwig Institute For Cancer Research Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof
US6071890A (en) 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
US5840839A (en) * 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003205A1 (en) * 1992-08-07 1994-02-17 Cytel Corporation Hla binding peptides and their uses
JPH08507525A (ja) * 1993-03-05 1996-08-13 サイテル コーポレイション Hla−a2.1結合ペプチドおよびそれらの使用
WO1996018409A1 (en) * 1994-12-14 1996-06-20 The Scripps Research Institute In vivo activation of tumor-specific cytotoxic t cells
WO1997041440A1 (en) * 1996-04-26 1997-11-06 Rijksuniversiteit Te Leiden Methods for selecting and producing t cell peptide epitopes and vaccines incorporating said selected epitopes

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
JPN6009041194, Nature, 1991, Vol.351, pp.290−6 *
JPN6009041195, Science, 1992, Vol.255, pp.1264−6 *
JPN6009041196, Immunogenetics, 1995, Vol.41, pp.178−228 *
JPN6009041197, J. Immunol. Methods, 1997, Vol.205, pp.201−9 *
JPN6009041198, Hum. Immunol., 1997, Vol.53, pp.81−9 *
JPN6009041199, Hum Immunol, 199801, Vol.59, pp.1−14 *
JPN6009041200, Virology, 1982, Vol.121, pp.211−29 *
JPN6009041201, Cancer Res., 1997, Vol.57, pp.4570−7 *
JPN6009041202, J. Immunother. Emphasis Tumor Immunol., 1993, Vol.14, pp.121−6 *
JPN6009041203, Eur. J. Immunol., 1993, Vol.23, pp.2072−7 *
JPN6009041204, Proc. Natl. Acad. Sci. USA, 1995, Vol.92, pp.11993−7 *
JPN6010011073, Cancer Res., 19980615, Vol.58, pp.2601−5 *
JPN6010011074, J. Immunol., 199801, Vol.160, pp.328−33 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536522A (ja) * 2004-05-07 2007-12-13 ベックマン コールター インコーポレーティッド Ctlの媒介による抗原提示細胞の溶解を検出するためのmhc架橋系

Also Published As

Publication number Publication date
EP1089757A4 (en) 2002-10-30
AU4577899A (en) 2000-01-05
EP1089757B1 (en) 2009-04-22
ES2326146T3 (es) 2009-10-01
ATE429247T1 (de) 2009-05-15
CA2330824A1 (en) 1999-12-23
EP1089757A1 (en) 2001-04-11
EP2036573A1 (en) 2009-03-18
DE69940774D1 (de) 2009-06-04
WO1999065522A1 (en) 1999-12-23
JP2010090167A (ja) 2010-04-22

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