JP2002515019A5 - - Google Patents
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- Publication number
- JP2002515019A5 JP2002515019A5 JP1997502307A JP50230797A JP2002515019A5 JP 2002515019 A5 JP2002515019 A5 JP 2002515019A5 JP 1997502307 A JP1997502307 A JP 1997502307A JP 50230797 A JP50230797 A JP 50230797A JP 2002515019 A5 JP2002515019 A5 JP 2002515019A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/479,457 US5763430A (en) | 1995-06-07 | 1995-06-07 | Method of treating a viral infection by administering a steroid compound |
| US08/487,443 | 1995-06-07 | ||
| US08/475,572 | 1995-06-07 | ||
| US08/476,855 US5874597A (en) | 1995-06-07 | 1995-06-07 | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| US08/476,855 | 1995-06-07 | ||
| US08/483,059 | 1995-06-07 | ||
| US08/479,455 | 1995-06-07 | ||
| US08/483,057 US5795885A (en) | 1995-06-07 | 1995-06-07 | Method of inhibiting profileration of cells by administering an aminosterol compound |
| US08/483,057 | 1995-06-07 | ||
| US08/475,572 US5840936A (en) | 1995-06-07 | 1995-06-07 | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE) |
| US08/483,059 US5840740A (en) | 1995-06-07 | 1995-06-07 | Aminosterol compounds and a method of treating infection using the aminosterol compounds |
| US08/479,455 US5994336A (en) | 1995-06-07 | 1995-06-07 | Method of inhibiting proliferation of cells by administering an aminosterol compound |
| US08/479,457 | 1995-06-07 | ||
| US08/487,443 US5847172A (en) | 1995-06-07 | 1995-06-07 | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| PCT/US1996/010508 WO1996040728A2 (en) | 1995-06-07 | 1996-06-07 | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (nhe), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the nhe-inhibitory efficacy of compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007223309A Division JP2007314577A (ja) | 1995-06-07 | 2007-08-29 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002515019A JP2002515019A (ja) | 2002-05-21 |
| JP2002515019A5 true JP2002515019A5 (enExample) | 2004-07-29 |
| JP4104164B2 JP4104164B2 (ja) | 2008-06-18 |
Family
ID=27569803
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50230797A Expired - Lifetime JP4104164B2 (ja) | 1995-06-07 | 1996-06-07 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
| JP2007223309A Withdrawn JP2007314577A (ja) | 1995-06-07 | 2007-08-29 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007223309A Withdrawn JP2007314577A (ja) | 1995-06-07 | 2007-08-29 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0832094B1 (enExample) |
| JP (2) | JP4104164B2 (enExample) |
| AT (1) | ATE259375T1 (enExample) |
| AU (1) | AU723663C (enExample) |
| CA (1) | CA2223910C (enExample) |
| DE (1) | DE69631527T2 (enExample) |
| DK (1) | DK0832094T3 (enExample) |
| ES (1) | ES2216049T3 (enExample) |
| PT (1) | PT832094E (enExample) |
| WO (1) | WO1996040728A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856535A (en) * | 1994-08-18 | 1999-01-05 | Magainin Pharmaceuticals, Inc. | Aminosterol ester compounds |
| US6143738A (en) * | 1995-06-07 | 2000-11-07 | Magainin Pharmaceuticals, Inc. | Therapeutic uses for an aminosterol compound |
| US5792635A (en) * | 1995-06-07 | 1998-08-11 | Magainin Pharmaceuticals, Inc. | Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine |
| PT910382E (pt) * | 1996-04-26 | 2003-10-31 | Genaera Corp | Esqualamina em combinacao com outros agentes anti-cancro para o tratamento de tumores |
| US6596712B2 (en) | 1996-04-26 | 2003-07-22 | Genaera Corporation | Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities |
| US7410959B1 (en) * | 2000-07-13 | 2008-08-12 | Genaera Corporation | Therapeutic uses for aminosterol compounds |
| CA2255856C (en) * | 1996-05-17 | 2008-05-13 | Magainin Pharmaceuticals Inc. | Therapeutic uses for an aminosterol compound |
| WO1998019682A1 (en) * | 1996-11-01 | 1998-05-14 | Magainin Pharmaceuticals Inc. | Certain aminosterol compounds and uses therefor |
| US6262283B1 (en) | 1996-12-06 | 2001-07-17 | Magainin Pharmaceuticals Inc. | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds |
| DE19737463A1 (de) * | 1997-08-28 | 1999-03-04 | Hoechst Marion Roussel De Gmbh | Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden |
| AU5342701A (en) | 2000-04-12 | 2001-10-30 | Genaera Corp | A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group |
| WO2006119211A2 (en) * | 2005-05-02 | 2006-11-09 | Genaera Corporation | Methods and compositions for treating ocular disorders |
| AU2007240652A1 (en) * | 2006-04-21 | 2007-11-01 | Genaera Corporation | Induction of weight loss and the selective inhibition of PTP1B |
| CA2985271A1 (en) * | 2007-09-06 | 2009-03-12 | Ohr Pharmaceutical, Inc. | A method for treating diabetes |
| JP5634985B2 (ja) | 2008-05-09 | 2014-12-03 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | インスリン抵抗性およびβ−細胞機能障害に関連する疾患を治療するためのリメポリドを含む医薬組成物 |
| CN103957919B (zh) * | 2011-09-19 | 2018-10-16 | 瑞士苏黎世联邦理工学院 | RORγ调节剂 |
| KR20150003798A (ko) | 2012-04-20 | 2015-01-09 | 오에이치알 파마서티컬, 인코포레이티드 | Ptp1b 연관 질병의 치료용 아미노스테로이드 |
| RU2669800C2 (ru) | 2013-03-15 | 2018-10-16 | Брихэм Янг Юниверсити | Способы лечения воспаления, аутоиммунных расстройств и боли |
| US11524015B2 (en) | 2013-03-15 | 2022-12-13 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
| EP2781217A1 (en) * | 2013-03-18 | 2014-09-24 | ETH Zurich | ROR gamma modulators |
| US10040817B2 (en) | 2013-10-03 | 2018-08-07 | Enterin Laboratories, Inc. | Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same |
| US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
| US20150203527A1 (en) | 2014-01-23 | 2015-07-23 | Brigham Young University | Cationic steroidal antimicrobials |
| US10441595B2 (en) * | 2014-06-26 | 2019-10-15 | Brigham Young University | Methods for treating fungal infections |
| FR3033563B1 (fr) * | 2015-03-12 | 2018-04-13 | Virbac | Composes analogues de la squalamine utiles comme agents antibacteriens |
| FR3055801B1 (fr) * | 2016-09-15 | 2020-10-30 | Virbac | Derives esters de squalamine pour le traitement des infections |
| US11083735B2 (en) | 2017-09-08 | 2021-08-10 | Enterin, Inc. | Methods for treating sleep disorders, sleep disturbances, and related symptoms using aminosterol compositions |
| EP3829587A4 (en) * | 2018-08-03 | 2022-07-20 | Enterin, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF BRAIN AND GUESS DISORDERS |
| US11464789B2 (en) | 2018-08-03 | 2022-10-11 | Enterin, Inc. | Aminosterol compositions and methods of using the same for treating schizophrenia |
| US12186328B2 (en) | 2019-05-23 | 2025-01-07 | Brigham Young University | Use of CSA compounds to stimulate stem cells and hair growth |
| CA3149479A1 (en) * | 2019-08-02 | 2021-02-11 | Enterin, Inc. | Human aminosterol ent-03 compounds, related compositions comprising the same, and methods of using the same |
| WO2021025974A1 (en) * | 2019-08-02 | 2021-02-11 | Enterin, Inc. | Human squalamine derivatives, related compositions comprising the same, and methods of using the same |
| CN112782300B (zh) * | 2020-12-25 | 2022-04-12 | 山东省食品药品检验研究院 | 一种胆烷酸的同分异构体及其检测方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192756A (en) * | 1992-03-18 | 1993-03-09 | The Children's Hospital Of Pennsylvania | Aminosterol antibiotic |
| WO1994019366A1 (en) * | 1993-02-26 | 1994-09-01 | Magainin Pharmaceuticals Inc. | Chemical synthesis of squalamine |
| CA2157594A1 (en) * | 1993-03-10 | 1994-09-15 | Leah L. Frye | Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants |
-
1996
- 1996-06-07 DK DK96922490T patent/DK0832094T3/da active
- 1996-06-07 EP EP96922490A patent/EP0832094B1/en not_active Expired - Lifetime
- 1996-06-07 CA CA002223910A patent/CA2223910C/en not_active Expired - Lifetime
- 1996-06-07 WO PCT/US1996/010508 patent/WO1996040728A2/en not_active Ceased
- 1996-06-07 ES ES96922490T patent/ES2216049T3/es not_active Expired - Lifetime
- 1996-06-07 AU AU63349/96A patent/AU723663C/en not_active Ceased
- 1996-06-07 EP EP04002943A patent/EP1420027A3/en not_active Withdrawn
- 1996-06-07 PT PT96922490T patent/PT832094E/pt unknown
- 1996-06-07 AT AT96922490T patent/ATE259375T1/de not_active IP Right Cessation
- 1996-06-07 JP JP50230797A patent/JP4104164B2/ja not_active Expired - Lifetime
- 1996-06-07 DE DE69631527T patent/DE69631527T2/de not_active Expired - Lifetime
-
2007
- 2007-08-29 JP JP2007223309A patent/JP2007314577A/ja not_active Withdrawn