JP2002514578A - ２−フタルイミジノグルタル酸の類似体および血管新生の阻害剤としてのそれらの使用 - Google Patents
２−フタルイミジノグルタル酸の類似体および血管新生の阻害剤としてのそれらの使用Info
- Publication number
- JP2002514578A JP2002514578A JP2000547948A JP2000547948A JP2002514578A JP 2002514578 A JP2002514578 A JP 2002514578A JP 2000547948 A JP2000547948 A JP 2000547948A JP 2000547948 A JP2000547948 A JP 2000547948A JP 2002514578 A JP2002514578 A JP 2002514578A
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- acid
- phthalimidinoglutaric acid
- phthalimidinoglutaric
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Ophthalmology & Optometry (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8503798P | 1998-05-11 | 1998-05-11 | |
| US9738498P | 1998-08-21 | 1998-08-21 | |
| US10803798P | 1998-11-12 | 1998-11-12 | |
| US60/085,037 | 1998-11-12 | ||
| US60/097,384 | 1998-11-12 | ||
| US60/108,037 | 1998-11-12 | ||
| PCT/US1999/010287 WO1999058096A2 (en) | 1998-05-11 | 1999-05-11 | Analogs of 2-phthalimidinoglutaric acid and their use as inhibitors of angiogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002514578A true JP2002514578A (ja) | 2002-05-21 |
| JP2002514578A5 JP2002514578A5 (https=) | 2006-05-18 |
Family
ID=27374997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000547948A Pending JP2002514578A (ja) | 1998-05-11 | 1999-05-11 | ２−フタルイミジノグルタル酸の類似体および血管新生の阻害剤としてのそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1091726A2 (https=) |
| JP (1) | JP2002514578A (https=) |
| KR (1) | KR100699968B1 (https=) |
| AU (1) | AU749356B2 (https=) |
| CA (1) | CA2331461C (https=) |
| WO (1) | WO1999058096A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006509743A (ja) * | 2002-10-31 | 2006-03-23 | セルジーン・コーポレーション | 黄斑変性の治療および管理のための選択的サイトカイン阻害薬の使用方法およびそれを含む組成物 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7182953B2 (en) * | 1999-12-15 | 2007-02-27 | Celgene Corporation | Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders |
| AU2002306596B2 (en) | 2001-02-27 | 2008-01-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| US7776907B2 (en) | 2002-10-31 | 2010-08-17 | Celgene Corporation | Methods for the treatment and management of macular degeneration using cyclopropyl-N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| CN1867331B (zh) | 2003-09-17 | 2010-05-26 | 美国政府健康及人类服务部 | 作为TNF-α调节剂的沙利度胺类似物 |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| CN102603610B (zh) * | 2012-02-21 | 2014-07-09 | 四川大学 | 1,3-二氢-1-氧-2h-异吲哚类化合物、其制备方法和用途 |
| CN104045594B (zh) * | 2012-02-21 | 2016-08-17 | 四川大学 | 一类1,3-二氢-1-氧-2h-异吲哚类化合物及其用途 |
| US9617212B2 (en) | 2013-12-17 | 2017-04-11 | Controlled Chemicals, Inc. | Isoindolin-1-ones as macrophage migration inhibitory factor (MIF) inhibitors |
| CN109467550B (zh) * | 2017-12-31 | 2022-02-18 | 苏州亚科科技股份有限公司 | 一种邻苯二甲酰胺基-l-谷氨酸酐的合成方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0892092A (ja) * | 1994-06-24 | 1996-04-09 | Gruenenthal Gmbh | 薬学的有効物質としてラクタム化合物を使用する方法 |
| JPH08507767A (ja) * | 1993-03-01 | 1996-08-20 | ザ・チルドレンズ・メデイカル・センター・コーポレーシヨン | 管脈形成を抑制する方法および組成物 |
-
1999
- 1999-05-11 WO PCT/US1999/010287 patent/WO1999058096A2/en not_active Ceased
- 1999-05-11 CA CA002331461A patent/CA2331461C/en not_active Expired - Fee Related
- 1999-05-11 JP JP2000547948A patent/JP2002514578A/ja active Pending
- 1999-05-11 EP EP99925585A patent/EP1091726A2/en not_active Withdrawn
- 1999-05-11 KR KR1020007012550A patent/KR100699968B1/ko not_active Expired - Fee Related
- 1999-05-11 AU AU41837/99A patent/AU749356B2/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08507767A (ja) * | 1993-03-01 | 1996-08-20 | ザ・チルドレンズ・メデイカル・センター・コーポレーシヨン | 管脈形成を抑制する方法および組成物 |
| JPH0892092A (ja) * | 1994-06-24 | 1996-04-09 | Gruenenthal Gmbh | 薬学的有効物質としてラクタム化合物を使用する方法 |
Non-Patent Citations (2)
| Title |
|---|
| JPN6009052468, ＰＯＬＡＴ，Ｔ． ｅｔ ａｌ, "Ｅｎｚｙｍｅ ｃａｔａｌｙｚｅｄ ｒｅｇｉｏｓｅｌｅｃｔｉｖｅ ｓｙｎｔｈｅｓｉｓ ｏｆ ｓｕｃｒｏｓｅ ｆａｔｔｙ ａｃｉｄ ｅｓｔｅｒ ｓｕｒｆａｃｔａｎｔｓ．", Ｊ Ｃａｒｂｏｈｙｄｒ Ｃｈｅｍ, 1997, Ｖｏｌ．１６， Ｎｏ．９, ｐ．１３１９−１３２５ * |
| JPN6009052470, ＳＨＡＨ，Ｊ．Ｈ． ｅｔ ａｌ, "Ｓｙｎｔｈｅｓｉｓ ａｎｄ ｅｎａｎｔｉｏｍｅｒｉｃ ｓｅｐａｒａｔｉｏｎ ｏｆ ２−ｐｈｔｈａｌｉｍｉｄｉｎｏ−ｇｌｕｔａｒｉｃ ａｃｉｄ ａｎａｌｏｇｕｅｓ： ｐｏｔｅｎｔ ｉｎｈｉｂｉｔｏｒｓ", Ｊ Ｍｅｄ Ｃｈｅｍ, 1999, Ｖｏｌ．４２， Ｎｏ．１６, ｐ．３０１４−７ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006509743A (ja) * | 2002-10-31 | 2006-03-23 | セルジーン・コーポレーション | 黄斑変性の治療および管理のための選択的サイトカイン阻害薬の使用方法およびそれを含む組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2331461A1 (en) | 1999-11-18 |
| AU4183799A (en) | 1999-11-29 |
| KR20010052332A (ko) | 2001-06-25 |
| CA2331461C (en) | 2008-10-07 |
| WO1999058096A2 (en) | 1999-11-18 |
| WO1999058096A9 (en) | 2000-07-13 |
| KR100699968B1 (ko) | 2007-03-28 |
| AU749356B2 (en) | 2002-06-27 |
| WO1999058096A3 (en) | 2000-05-18 |
| EP1091726A2 (en) | 2001-04-18 |
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