JP2002513409A5 - - Google Patents

Download PDF

Info

Publication number
JP2002513409A5
JP2002513409A5 JP1998538798A JP53879898A JP2002513409A5 JP 2002513409 A5 JP2002513409 A5 JP 2002513409A5 JP 1998538798 A JP1998538798 A JP 1998538798A JP 53879898 A JP53879898 A JP 53879898A JP 2002513409 A5 JP2002513409 A5 JP 2002513409A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998538798A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002513409A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/004299 external-priority patent/WO1998039329A1/en
Publication of JP2002513409A publication Critical patent/JP2002513409A/ja
Publication of JP2002513409A5 publication Critical patent/JP2002513409A5/ja
Ceased legal-status Critical Current

Links

JP53879898A 1997-03-04 1998-03-04 アミド芳香環スルホンアミドヒドロキサム酸化合物 Ceased JP2002513409A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3979597P 1997-03-04 1997-03-04
US60/039,795 1997-03-04
PCT/US1998/004299 WO1998039329A1 (en) 1997-03-04 1998-03-04 Amidoaromatic ring sulfonamide hydroxamic acid compounds

Publications (2)

Publication Number Publication Date
JP2002513409A JP2002513409A (ja) 2002-05-08
JP2002513409A5 true JP2002513409A5 (https=) 2005-11-10

Family

ID=21907383

Family Applications (2)

Application Number Title Priority Date Filing Date
JP53879898A Ceased JP2002513409A (ja) 1997-03-04 1998-03-04 アミド芳香環スルホンアミドヒドロキサム酸化合物
JP53879798A Abandoned JP2002513408A (ja) 1997-03-04 1998-03-04 チオールスルホンアミドヒドロキサム酸化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP53879798A Abandoned JP2002513408A (ja) 1997-03-04 1998-03-04 チオールスルホンアミドヒドロキサム酸化合物

Country Status (10)

Country Link
US (1) US6451791B1 (https=)
EP (2) EP0977745B1 (https=)
JP (2) JP2002513409A (https=)
AT (2) ATE287885T1 (https=)
CA (2) CA2282399A1 (https=)
DE (2) DE69828783T2 (https=)
DK (2) DK0983267T3 (https=)
ES (2) ES2234103T3 (https=)
PT (1) PT983267E (https=)
WO (1) WO1998039329A1 (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747027B1 (en) 1996-07-22 2004-06-08 Pharmacia Corporation Thiol sulfonamide metalloprotease inhibitors
US6358980B1 (en) 1999-01-27 2002-03-19 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
US6946473B2 (en) 1999-01-27 2005-09-20 Wyeth Holdings Corporation Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6800646B1 (en) 1999-02-08 2004-10-05 Pharmacia Corporation Sulfamato hydroxamic acid metalloprotease inhibitor
AU6049800A (en) * 1999-07-16 2001-02-05 G.D. Searle & Co. Method of changing conformation of a matrix metalloproteinase
US6869951B1 (en) 1999-07-16 2005-03-22 Pharmacia Corporation Method of changing conformation of a matrix metalloproteinase
EP1088815A1 (en) * 1999-09-28 2001-04-04 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonyl amino acid derivatives
WO2001027084A1 (en) * 1999-10-14 2001-04-19 The Procter & Gamble Company Beta disubstituted metalloprotease inhibitors
US6696456B1 (en) 1999-10-14 2004-02-24 The Procter & Gamble Company Beta disubstituted metalloprotease inhibitors
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
NZ520657A (en) 2000-03-21 2004-11-26 Procter & Gamble Heterocyclic side chain containing, N-substituted metalloprotease inhibitors
WO2001070693A2 (en) 2000-03-21 2001-09-27 The Procter & Gamble Company Difluorobutyric acid derivatives and their use as metalloprotease inhibitors
WO2002003994A1 (en) * 2000-07-12 2002-01-17 G.D. Searle & Co. N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase
EP2295081B1 (en) 2001-06-26 2018-10-31 Amgen Inc. Antibodies to OPGL
BR0213736A (pt) 2001-11-01 2004-10-19 Wyeth Corp ácidos hidroxâmicos de sulfonamida de arila alênica como metaloproteinase matriz e inibidores de tace
WO2003091247A2 (en) 2002-04-25 2003-11-06 Pharmacia Corporation Piperidinyl-and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors
KR100701811B1 (ko) 2002-05-29 2007-04-02 머크 앤드 캄파니 인코포레이티드 탄저병의 치료 및 치사 인자의 억제에 유용한 화합물
US7199155B2 (en) 2002-12-23 2007-04-03 Wyeth Holdings Corporation Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors
AU2003300076C1 (en) 2002-12-30 2010-03-04 Angiotech International Ag Drug delivery from rapid gelling polymer composition
AU2005250351A1 (en) 2004-05-11 2005-12-15 Merck & Co., Inc. Process for making n-sulfonated-amino acid derivatives
CA2627497C (en) * 2005-10-28 2014-10-14 Takeda Pharmaceutical Company Limited Heterocyclic amide compound and use thereof
KR20080104347A (ko) * 2006-03-29 2008-12-02 노파르티스 아게 선택적 히드록사메이트-기재 mmp 억제제
EP2149568A1 (en) 2008-07-22 2010-02-03 Bracco Imaging S.p.A Aryl-sulphonamidic dimers as metalloproteases inhibitors
EP2147684A1 (en) 2008-07-22 2010-01-27 Bracco Imaging S.p.A Diagnostic Agents Selective Against Metalloproteases
US9023318B2 (en) 2011-06-08 2015-05-05 Siemens Medical Solutions Usa, Inc. Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof
CA3082972C (en) 2017-11-27 2022-10-11 Council Of Scientific & Industrial Research Indole (sulfomyl) n-hydroxy benzamide derivatives as selective hdac inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337197A (en) 1980-10-31 1982-06-29 E. R. Squibb & Sons, Inc. O-sulfated β-lactam hydroxamic acids and intermediates
US5455258A (en) * 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5646167A (en) * 1993-01-06 1997-07-08 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamix acids
US5552419A (en) * 1993-01-06 1996-09-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
CA2193691A1 (en) * 1994-06-22 1995-12-28 Andrew Miller Metalloproteinase inhibitors
GB9503749D0 (en) * 1995-02-24 1995-04-12 British Biotech Pharm Synthesis of hydroxamic acid derivatives
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
PT757984E (pt) * 1995-08-08 2003-02-28 Ono Pharmaceutical Co Derivados de acido hidroxamico uteis para inibir a gelatinase
ES2233275T3 (es) * 1995-12-08 2005-06-16 Agouron Pharmaceuticals, Inc. Intermediarios que sirven para la preparacion de inhibidores de metaloproteinasas.
BR9707010B1 (pt) * 1996-01-23 2009-05-05 compostos, composição farmacêutica e composições para inibir metaloproteinase e colagenase do tipo iv.
CA2242416C (en) 1996-01-23 2006-03-21 Shionogi & Co., Ltd. Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same
GB9715962D0 (en) * 1996-08-23 1997-10-01 Zeneca Ltd Sulfonamides

Similar Documents

Publication Publication Date Title
JP2000509942A5 (https=)
JP2000509637A5 (https=)
JP2000510751A5 (https=)
JP2001526857A5 (https=)
JP2000509912A5 (https=)
JP2000509635A5 (https=)
JP2001515470A5 (https=)
JP2000514276A5 (https=)
JP2002509534A5 (https=)
JP2000509587A5 (https=)
JP2000508866A5 (https=)
JP2000510793A5 (https=)
JP2000508841A5 (https=)
JP2002513409A5 (https=)
JP2000508680A5 (https=)
JP2001526709A5 (https=)
JP2000509804A5 (https=)
JP2000509853A5 (https=)
JP2000509755A5 (https=)
JP2000510247A5 (https=)
JP2000510969A5 (https=)
JP2000508836A5 (https=)
JP2000509818A5 (https=)
JP2000509520A5 (https=)
JP2001517212A5 (https=)