JP2002507407A - 心臓由来幹細胞 - Google Patents

心臓由来幹細胞

Info

Publication number
JP2002507407A
JP2002507407A JP2000537976A JP2000537976A JP2002507407A JP 2002507407 A JP2002507407 A JP 2002507407A JP 2000537976 A JP2000537976 A JP 2000537976A JP 2000537976 A JP2000537976 A JP 2000537976A JP 2002507407 A JP2002507407 A JP 2002507407A
Authority
JP
Japan
Prior art keywords
cells
heart
adherent
cell
derived stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000537976A
Other languages
English (en)
Japanese (ja)
Inventor
エー． デイシャー，テレサ
ハンソン，ビルギット
イー． ムーア，エマ
エル． ロバートソン，タマラ
エル． トンプソン，デボラ
ディー． ラム，カレン
Original Assignee
ザイモジェネティクス，インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザイモジェネティクス，インコーポレイティド filed Critical ザイモジェネティクス，インコーポレイティド
Publication of JP2002507407A publication Critical patent/JP2002507407A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000537976A 1998-03-23 1999-03-23 心臓由来幹細胞 Pending JP2002507407A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7913298P 1998-03-23 1998-03-23
US60/079,132 1998-03-23
PCT/US1999/006356 WO1999049015A2 (fr) 1998-03-23 1999-03-23 Cellules souches d'origine cardiaque

Publications (1)

Publication Number Publication Date
JP2002507407A true JP2002507407A (ja) 2002-03-12

Family

ID=22148638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000537976A Pending JP2002507407A (ja) 1998-03-23 1999-03-23 心臓由来幹細胞

Country Status (5)

Country Link
EP (1) EP1064356A2 (fr)
JP (1) JP2002507407A (fr)
AU (1) AU3112499A (fr)
CA (1) CA2324350A1 (fr)
WO (1) WO1999049015A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010511051A (ja) * 2006-11-28 2010-04-08 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 心臓病理学を処置するための筋肉由来の細胞およびその作製法および使用法

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US7514074B2 (en) 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
EP1100870B1 (fr) * 1998-07-31 2008-01-02 Genzyme Corporation Amelioration du fonctionnement cardiaque par transplantation de cellules souches mesenchymateuses
EP1894997A1 (fr) * 1998-07-31 2008-03-05 Genzyme Corporation Amélioration de la fonction cardiaque par transplantation de cellules souches mésenchymateuses
FR2810045B1 (fr) * 2000-06-07 2004-09-03 Assist Publ Hopitaux De Paris Procede d'obtention de population cellulaires caracterisees d'origine musculaire et utilisations
WO2002009650A2 (fr) 2000-07-31 2002-02-07 New York Medical College Compositions et procedes destines a la reparation et/ou la regeneration d'un myocarde endommage
US7862810B2 (en) 2000-07-31 2011-01-04 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
ES2558626T3 (es) * 2001-02-14 2016-02-05 Anthrogenesis Corporation Placenta post-parto de mamíferos, su uso y células madre placentarias de la misma
DK2105497T3 (da) * 2001-04-24 2019-06-24 Dolores Baksh Progenitorcellepopulationer, ekspansion heraf samt vækst af ikke-hæmatopoietiske celletyper og væv fra disse
WO2002088335A1 (fr) * 2001-04-24 2002-11-07 Ajinomoto Co., Inc. Cellules souches et procede d'extraction de ces cellules
JP2003018984A (ja) * 2001-07-06 2003-01-21 Mitsubishi Chemicals Corp 多分化能を有する細胞の製造法
US7732199B2 (en) 2001-07-12 2010-06-08 Geron Corporation Process for making transplantable cardiomyocytes from human embryonic stem cells
US7425448B2 (en) 2001-07-12 2008-09-16 Geron Corporation Cardiomyocyte precursors from human embryonic stem cells
EP1435977A4 (fr) 2001-09-19 2005-06-08 Ford Henry Health System Transplantation cardiaque de cellules souches pour le traitement de l'insuffisance cardiaque
US20040247575A1 (en) 2003-06-03 2004-12-09 Caplice Noel M. Smooth muscle progenitor cells
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
US7452718B2 (en) 2004-03-26 2008-11-18 Geron Corporation Direct differentiation method for making cardiomyocytes from human embryonic stem cells
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
WO2006052925A2 (fr) * 2004-11-08 2006-05-18 The Johns Hopkins University Cellules souches cardiaques
DE602006017071D1 (de) 2005-01-25 2010-11-04 Five Prime Therapeutics Inc Zusammensetzungen und verfahren zur behandlung von herzkrankheiten
CN101228264B (zh) 2005-06-22 2017-12-26 阿斯特利亚斯生物治疗股份公司 使灵长类多能干细胞分化成心肌细胞系细胞
EP1790350A1 (fr) * 2005-11-24 2007-05-30 Interstitial Therapeutics Utilisation d'une composition contenant de la kératinocyte pour le traitement de la restenose
CN101384706B (zh) 2006-02-16 2013-11-06 圣拉法埃莱医院有限公司 骨骼肌周成血管细胞和心脏中成血管细胞、其分离方法和用途
US8119123B2 (en) 2006-02-16 2012-02-21 New York Medical College Compositions comprising vascular and myocyte progenitor cells and methods of their use
WO2008081457A2 (fr) * 2007-01-04 2008-07-10 Ramot At Tel Aviv University Ltd. Méthodes d'isolation de cellules souches cardiaques, constitution de banques de cellules souches et utilisations de celles-ci
DE102007008650B4 (de) 2007-02-20 2012-06-06 Charité - Universitätsmedizin Berlin Zellen zur Therapie des Herzens
US8512696B2 (en) 2007-11-30 2013-08-20 Autologous, Llc Methods of isolating non-senescent cardiac stem cells and uses thereof
AU2008334036B2 (en) 2007-11-30 2014-05-29 New York Medical College Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
WO2009097411A1 (fr) 2008-01-30 2009-08-06 Geron Corporation Surfaces synthétiques pour la culture de cardiomyocytes issus de cellules souches
EP2451941B1 (fr) * 2009-07-09 2018-06-13 Janssen Biotech, Inc. Cellules dérivées de tissus cardiaques
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
WO2012048275A2 (fr) 2010-10-08 2012-04-12 Caridianbct, Inc. Procédés et systèmes configurables pour la culture et la récolte de cellules dans un système de bioréacteur à fibres creuses
AU2012204501B2 (en) 2011-01-03 2016-05-19 Avm Biotechnology, Llc Personalized production of biologics and method for reprogramming somatic cells
EP2861238A4 (fr) 2012-06-05 2016-03-16 Capricor Inc Procédés optimisés pour générer des cellules souches cardiaques à partir de tissu cardiaque et leur utilisation dans une thérapie cardiaque
EP2882445B1 (fr) 2012-08-13 2019-04-24 Cedars-Sinai Medical Center Exosomes et acides micro-ribonucléiques pour la régénération de tissus
JP6612227B2 (ja) 2013-11-16 2019-11-27 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
EP3122866B1 (fr) 2014-03-25 2019-11-20 Terumo BCT, Inc. Remplacement passif de milieu
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
US11357799B2 (en) 2014-10-03 2022-06-14 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
EP3402543B1 (fr) 2016-01-11 2021-09-08 Cedars-Sinai Medical Center Cellules dérivées de cardiosphères et exosomes sécrétés par ces cellules dans le traitement d'une insuffisance cardiaque à fraction d'éjection préservée
JP7034949B2 (ja) 2016-05-25 2022-03-14 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖
US11351200B2 (en) 2016-06-03 2022-06-07 Cedars-Sinai Medical Center CDC-derived exosomes for treatment of ventricular tachyarrythmias
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
WO2018026766A1 (fr) 2016-08-01 2018-02-08 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions et procédés pour traiter une affection cardiaque
WO2018057542A1 (fr) 2016-09-20 2018-03-29 Cedars-Sinai Medical Center Cellules dérivées de cardiosphères et leurs vésicules extracellulaires pour retarder ou inverser le vieillissement et des troubles liés à l'âge
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3612191A4 (fr) 2017-04-19 2020-12-30 Cedars-Sinai Medical Center Méthodes et compositions pour traiter une dystrophie musculaire squelettique
US11660355B2 (en) 2017-12-20 2023-05-30 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion

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EP0804554A1 (fr) * 1994-09-09 1997-11-05 ZymoGenetics, Inc. Preparation de cellules immortelles
DE4441327C1 (de) * 1994-11-22 1995-11-09 Inst Pflanzengenetik & Kultur Embryonale Herzmuskelzellen, ihre Herstellung und ihre Verwendung
US5919449A (en) * 1995-05-30 1999-07-06 Diacrin, Inc. Porcine cardiomyocytes and their use in treatment of insufficient cardiac function

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010511051A (ja) * 2006-11-28 2010-04-08 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 心臓病理学を処置するための筋肉由来の細胞およびその作製法および使用法

Also Published As

Publication number Publication date
CA2324350A1 (fr) 1999-09-30
WO1999049015A2 (fr) 1999-09-30
WO1999049015A3 (fr) 1999-12-16
AU3112499A (en) 1999-10-18
EP1064356A2 (fr) 2001-01-03

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