JP2002506445A5 - - Google Patents

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Publication number
JP2002506445A5
JP2002506445A5 JP1999504593A JP50459399A JP2002506445A5 JP 2002506445 A5 JP2002506445 A5 JP 2002506445A5 JP 1999504593 A JP1999504593 A JP 1999504593A JP 50459399 A JP50459399 A JP 50459399A JP 2002506445 A5 JP2002506445 A5 JP 2002506445A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1999504593A
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English (en)
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JP2002506445A (ja
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Priority claimed from PCT/US1998/012231 external-priority patent/WO1998058636A1/en
Publication of JP2002506445A publication Critical patent/JP2002506445A/ja
Publication of JP2002506445A5 publication Critical patent/JP2002506445A5/ja
Ceased legal-status Critical Current

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Figure 2002506445
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Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
Figure 2002506445
JP50459399A 1997-06-20 1998-06-15 スーパーオキシドラジカルの不均化反応のための合成触媒を用いる鎮痛方法 Ceased JP2002506445A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5040297P 1997-06-20 1997-06-20
US60/050,402 1997-06-20
PCT/US1998/012231 WO1998058636A1 (en) 1997-06-20 1998-06-15 Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals

Publications (2)

Publication Number Publication Date
JP2002506445A JP2002506445A (ja) 2002-02-26
JP2002506445A5 true JP2002506445A5 (ja) 2007-12-06

Family

ID=21965044

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50459399A Ceased JP2002506445A (ja) 1997-06-20 1998-06-15 スーパーオキシドラジカルの不均化反応のための合成触媒を用いる鎮痛方法

Country Status (12)

Country Link
US (2) US6180620B1 (ja)
EP (1) EP1001752B1 (ja)
JP (1) JP2002506445A (ja)
AT (1) ATE256467T1 (ja)
AU (1) AU733415B2 (ja)
CA (1) CA2294155A1 (ja)
DE (1) DE69820633T2 (ja)
DK (1) DK1001752T3 (ja)
ES (1) ES2215305T3 (ja)
PT (1) PT1001752E (ja)
WO (1) WO1998058636A1 (ja)
ZA (1) ZA985376B (ja)

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US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US6214817B1 (en) * 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
US20050171198A1 (en) * 1997-06-20 2005-08-04 Metaphore Pharmaceuticals, Inc. SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease
US20060270639A1 (en) * 1997-06-20 2006-11-30 Daniela Salvemini Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs
JP2001521939A (ja) 1997-11-03 2001-11-13 デューク・ユニバーシティー 置換されたポルフィリン類
WO2000043395A1 (en) 1999-01-25 2000-07-27 National Jewish Medical And Research Center Substituted porphyrins
ATE291446T1 (de) * 1999-05-27 2005-04-15 Monsanto Co Biomaterialien, modifiziert mit superoxid- dismutase imitatoren
US20030069281A1 (en) * 2000-06-14 2003-04-10 Irwin Fridovich Tetrapyrroles
US20020072512A1 (en) * 2000-12-08 2002-06-13 Metaphore Pharmaceuticals, Inc Method of preventing and treating HIV-mediated central nervous system damage
ATE464061T1 (de) * 2001-01-05 2010-04-15 Metaphore Pharmaceuticals Inc Zusammensetzungen und verfahren zur erhöhung der zytokin-aktivität und zur behandlung der hypotension assoziiert mit der verabreichung von zytokinen
ES2330728T3 (es) * 2001-01-19 2009-12-15 National Jewish Health Medicamento para proteccion en radioterapia.
AU2002236861A1 (en) * 2001-01-26 2002-08-06 Metaphore Pharmaceuticals, Inc. Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes
US20040137638A1 (en) * 2002-03-04 2004-07-15 Slomczynska Urszula J. Chromatography of metal complexes
JP4369124B2 (ja) * 2001-03-02 2009-11-18 メタファー・ファーマシューティカルズ・インコーポレイテッド 金属錯体のクロマトグラフィー
AU2002312194B8 (en) * 2001-06-01 2008-05-15 Aeolus Sciences, Inc. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
EP1417219A4 (en) * 2001-06-08 2005-05-25 Metaphore Pharmaceuticals Inc LIBRARIES OF PEPTIDES, CHIRAL AZACROWNS AND PEPTIDOMIMETICS WITH CONFORMATIONAL CONSTRAINTS AND METHODS OF MAKING THE SAME
US20040266742A1 (en) * 2001-06-26 2004-12-30 Daniela Salvemini Combination therapy of an sodm and a corticosteroid for prevention and/or treatment of inflammatory disease
WO2003039561A1 (en) * 2001-11-02 2003-05-15 Elan Corporation, Plc Pharmaceutical composition
DK1463563T3 (da) * 2001-12-14 2009-04-20 Alcon Inc Superoxiddismutas-mimetika til behandling af öjenlidelser og -sygdomme
US6933275B2 (en) * 2002-05-01 2005-08-23 The Board Of Trustees Of The Leland Stanford Junior University Protein kinase C peptides for use in withdrawal
JP2006501163A (ja) * 2002-06-07 2006-01-12 デューク・ユニバーシティー 置換ポルフィリン
US20030232784A1 (en) * 2002-06-14 2003-12-18 Benedict James J. Hyaluronic acid-associated superoxide dismutase mimics and their use in the treatment of joint pain
CA2397684A1 (en) * 2002-08-12 2004-02-12 Michael P. Murphy Mitochondrially targeted antioxidants
US8623412B2 (en) * 2002-09-23 2014-01-07 Elan Pharma International Limited Abuse-resistant pharmaceutical compositions
WO2004052227A2 (en) * 2002-12-06 2004-06-24 Alcon, Inc. Superoxide dismutase mimics for the treatment of ocular disorders and diseases
MXPA05005937A (es) * 2002-12-06 2005-08-18 Alcon Inc Imitaciones de superoxido de dismutasa para el tratamiento de trastornos y enfermedades oculares.
KR100648618B1 (ko) * 2003-11-19 2006-11-23 주식회사 웰스킨 활성 산소 억제제
JP2007513948A (ja) * 2003-12-11 2007-05-31 アルコン，インコーポレイテッド 視神経損傷および網膜損傷の処置のためのスーパーオキシドジスムターゼ模倣物
CA2591970C (en) * 2004-12-21 2014-08-19 Metaphore Pharmaceuticals, Inc Polyethylene glycolated superoxide dismutase mimetics
US8217166B2 (en) * 2005-05-05 2012-07-10 Galera Therapeutics, Llc Polyethylene glycolated superoxide dismutase mimetics
US20120301403A1 (en) 2007-06-21 2012-11-29 Galera Therapeutics, Llc Polyethylene glycolated superoxide dismutase mimetics
KR100724586B1 (ko) 2005-12-09 2007-06-04 세종대학교산학협력단 수퍼옥사이드 디스뮤타아제 활성을 갖는 고리화합물
EP2056675B1 (en) * 2006-10-12 2019-01-09 Galera Labs, LLC Methods of treating oral mucositis
US8486928B2 (en) 2007-11-14 2013-07-16 Galera Therapeutics Super-oxide dismutase mimetics
CA2724550C (en) 2008-05-22 2017-01-03 Kereos, Inc. Combination antitumor therapy
RU2506083C2 (ru) 2008-05-23 2014-02-10 Нэшнл Джуиш Хелт Способ лечения поражений, ассоциированных с воздействием алкилирующих веществ
US9149483B2 (en) 2011-09-26 2015-10-06 Galera Labs, Llc Methods for treatment of diseases
DK3334744T3 (da) * 2015-08-11 2020-07-27 Galera Labs Llc Makrocykliske pentaaza-ringkomplekser med oral biotilgængelighed
CA3053779A1 (en) * 2017-02-15 2018-08-23 Galera Labs, Llc Pentaaza macrocyclic ring complexes for local intestinal delivery
IL295620B2 (en) 2017-04-13 2024-01-01 Galera Labs Llc Cancer immunotherapy combined with a macrocyclic ring pentase complex
EP3388082A1 (en) 2017-04-13 2018-10-17 Galera Labs, LLC Combination cancer immunotherapy with pentaaza macrocyclic ring complex
CA3090129A1 (en) 2018-01-31 2019-08-08 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent
CA3167087A1 (en) 2020-02-13 2021-08-19 Anantha Rajmohan MUTHUSAMY Solid state forms of avasopasem manganese and process for preparation thereof

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JPH0751496B2 (ja) 1986-04-02 1995-06-05 武田薬品工業株式会社 リポソ−ムの製造法
US5216021A (en) 1986-08-28 1993-06-01 Sorenson John R J Analgesic method
US4999347A (en) 1986-08-28 1991-03-12 Sorenson John R J Analgesic method
JPS63313581A (ja) * 1987-06-16 1988-12-21 Ube Ind Ltd 修飾ス−パ−オキシドジスムタ−ゼ
CA2072934C (en) 1991-07-19 2007-08-28 Karl William Aston Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
JP3155552B2 (ja) 1991-07-19 2001-04-09 モンサント カンパニー 超酸化物の不均斉変化に有効な触媒としての窒素含有−大環状リガンドのマンガン錯体
CN1088086A (zh) * 1992-12-14 1994-06-22 西北大学 一种新型的护肤保健品
US6204259B1 (en) 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
US6525041B1 (en) 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
CN1225631A (zh) 1996-03-13 1999-08-11 孟山都公司 有歧化过氧化物催化剂效果的含氮大环配位体锰或铁配合物的生物缀合物

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