JP2002504325A - 転写因子stat1と転写因子usf1の間の結合を阻害する能力をもつ化合物のスクリーニング方法 - Google Patents
転写因子stat1と転写因子usf1の間の結合を阻害する能力をもつ化合物のスクリーニング方法Info
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- JP2002504325A JP2002504325A JP2000532511A JP2000532511A JP2002504325A JP 2002504325 A JP2002504325 A JP 2002504325A JP 2000532511 A JP2000532511 A JP 2000532511A JP 2000532511 A JP2000532511 A JP 2000532511A JP 2002504325 A JP2002504325 A JP 2002504325A
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|---|---|---|---|
| FR98/02025 | 1998-02-19 | ||
| FR9802025A FR2775003A1 (fr) | 1998-02-19 | 1998-02-19 | Methode de criblage de composes capables d'inhiber la fixation entre le facteur de transcription stat1 et le facteur de transcription usf1 |
| PCT/FR1999/000376 WO1999042571A1 (fr) | 1998-02-19 | 1999-02-19 | Methode de criblage de composes capables d'inhiber la fixation entre le facteur de transcription stat1 et le facteur de transcription usf1 |
Publications (2)
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| JP2002504325A true JP2002504325A (ja) | 2002-02-12 |
| JP2002504325A5 JP2002504325A5 (https=) | 2006-04-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2000532511A Pending JP2002504325A (ja) | 1998-02-19 | 1999-02-19 | 転写因子stat1と転写因子usf1の間の結合を阻害する能力をもつ化合物のスクリーニング方法 |
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| US (1) | US6379894B1 (https=) |
| EP (1) | EP1068310B1 (https=) |
| JP (1) | JP2002504325A (https=) |
| AU (1) | AU2431299A (https=) |
| DE (1) | DE69938450T2 (https=) |
| FR (1) | FR2775003A1 (https=) |
| WO (1) | WO1999042571A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10148886A1 (de) | 2001-10-04 | 2003-04-30 | Avontec Gmbh | Inhibition von STAT-1 |
Citations (2)
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| JPH09500026A (ja) * | 1994-04-14 | 1997-01-07 | リガンド・ファーマシューティカルズ・インコーポレーテッド | サイトカインに応答性のdnaスペーサー調節要素およびその使用方法 |
| WO1997002354A1 (en) * | 1995-06-30 | 1997-01-23 | Medical Research Council | INTERACTION OF p53 WITH TRANSCRIPTION FACTOR DP-1 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5976835A (en) * | 1992-03-19 | 1999-11-02 | The Rockefeller University | Nucleic acids encoding receptor recognition factor Stat1α and Stat1β, and methods of use thereof |
| DE69429608T2 (de) | 1993-08-26 | 2002-09-12 | Novimmune Sa, Genf/Geneve | MHC-Klasse-II Transaktivator (CIITA) und dessen Anwendungen |
| US5463023A (en) * | 1993-10-22 | 1995-10-31 | Washington University | Composition for inhibition of intracellular transcription |
| JPH09511908A (ja) * | 1994-04-14 | 1997-12-02 | リガンド・ファーマシューティカルズ・インコーポレイテッド | サイトカインに応答性のdna調節要素 |
| US5814517A (en) * | 1994-04-14 | 1998-09-29 | Ligand Pharmaceuticals, Inc. | DNA spacer regulatory elements responsive to cytokines and methods for their use |
| US5707803A (en) * | 1994-04-14 | 1998-01-13 | Ligand Pharmaceuticals, Inc. | DNA regulatory elements responsive to cytokines and methods for their use |
| US5672473A (en) | 1994-08-24 | 1997-09-30 | President And Fellows Of Harvard College | Methods of identifying compounds useful for treating autoimmune diseases |
| US5643726A (en) * | 1994-11-10 | 1997-07-01 | The General Hospital Corporation | Methods for modulating transcription from the amyloid β-protein precursor (APP) promoter |
| US5716622A (en) * | 1995-01-06 | 1998-02-10 | The Rockefeller University | Functionally active regions of signal transducer and activators of transcription |
| US5821053A (en) * | 1995-02-10 | 1998-10-13 | Center For Blood Research, Inc. | LIL-Stat DNA binding sites and methods for identifying inhibitory binding agents |
| ZA97476B (en) * | 1996-01-22 | 1998-07-21 | Res Dev Foundation | Novel methods for the characterization of compounds which stimulate STF-1 expression in pancreatic islet cells. |
| FR2762327B1 (fr) * | 1997-04-22 | 1999-07-02 | Transgene Sa | Sequence d'acide nucleique de genes ciita, susceptibles d'etre impliquees dans le controle et la regulation de l'expression de genes codant pour des molecules mhc de type ii et leur utilisation, notamment comme medicament |
| US6207391B1 (en) * | 1998-03-31 | 2001-03-27 | Tularik Inc. | High-throughput screening assays for modulators of STAT4 and STAT6 activity |
| US6235873B1 (en) * | 1999-07-31 | 2001-05-22 | The Rockefeller University | Constitutively active transcription factors and their uses for identifying modulators of activity including dysproliferative cellular changes |
-
1998
- 1998-02-19 FR FR9802025A patent/FR2775003A1/fr active Pending
-
1999
- 1999-02-19 AU AU24312/99A patent/AU2431299A/en not_active Abandoned
- 1999-02-19 DE DE69938450T patent/DE69938450T2/de not_active Expired - Fee Related
- 1999-02-19 JP JP2000532511A patent/JP2002504325A/ja active Pending
- 1999-02-19 WO PCT/FR1999/000376 patent/WO1999042571A1/fr not_active Ceased
- 1999-02-19 EP EP99903787A patent/EP1068310B1/fr not_active Expired - Lifetime
-
2000
- 2000-08-18 US US09/641,999 patent/US6379894B1/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09500026A (ja) * | 1994-04-14 | 1997-01-07 | リガンド・ファーマシューティカルズ・インコーポレーテッド | サイトカインに応答性のdnaスペーサー調節要素およびその使用方法 |
| WO1997002354A1 (en) * | 1995-06-30 | 1997-01-23 | Medical Research Council | INTERACTION OF p53 WITH TRANSCRIPTION FACTOR DP-1 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6009013765, Immunity, 19980201, Vol.8, p.157−166 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1068310B1 (fr) | 2008-04-02 |
| WO1999042571A1 (fr) | 1999-08-26 |
| DE69938450T2 (de) | 2009-05-07 |
| US6379894B1 (en) | 2002-04-30 |
| EP1068310A1 (fr) | 2001-01-17 |
| FR2775003A1 (fr) | 1999-08-20 |
| DE69938450D1 (de) | 2008-05-15 |
| WO1999042571A8 (fr) | 1999-11-18 |
| AU2431299A (en) | 1999-09-06 |
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