AU2431299A - Method for screening compounds capable of inhibiting fixing between the transcription factor of stat1 and the transcription factor of usf1 - Google Patents

Method for screening compounds capable of inhibiting fixing between the transcription factor of stat1 and the transcription factor of usf1

Info

Publication number
AU2431299A
AU2431299A AU24312/99A AU2431299A AU2431299A AU 2431299 A AU2431299 A AU 2431299A AU 24312/99 A AU24312/99 A AU 24312/99A AU 2431299 A AU2431299 A AU 2431299A AU 2431299 A AU2431299 A AU 2431299A
Authority
AU
Australia
Prior art keywords
transcription factor
usf1
stat1
compounds capable
screening compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU24312/99A
Other languages
English (en)
Inventor
Bernard Mach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novimmune SA
Original Assignee
Novimmune SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novimmune SA filed Critical Novimmune SA
Publication of AU2431299A publication Critical patent/AU2431299A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU24312/99A 1998-02-19 1999-02-19 Method for screening compounds capable of inhibiting fixing between the transcription factor of stat1 and the transcription factor of usf1 Abandoned AU2431299A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9802025 1998-02-19
FR9802025A FR2775003A1 (fr) 1998-02-19 1998-02-19 Methode de criblage de composes capables d'inhiber la fixation entre le facteur de transcription stat1 et le facteur de transcription usf1
PCT/FR1999/000376 WO1999042571A1 (fr) 1998-02-19 1999-02-19 Methode de criblage de composes capables d'inhiber la fixation entre le facteur de transcription stat1 et le facteur de transcription usf1

Publications (1)

Publication Number Publication Date
AU2431299A true AU2431299A (en) 1999-09-06

Family

ID=9523151

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24312/99A Abandoned AU2431299A (en) 1998-02-19 1999-02-19 Method for screening compounds capable of inhibiting fixing between the transcription factor of stat1 and the transcription factor of usf1

Country Status (7)

Country Link
US (1) US6379894B1 (https=)
EP (1) EP1068310B1 (https=)
JP (1) JP2002504325A (https=)
AU (1) AU2431299A (https=)
DE (1) DE69938450T2 (https=)
FR (1) FR2775003A1 (https=)
WO (1) WO1999042571A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10148886A1 (de) 2001-10-04 2003-04-30 Avontec Gmbh Inhibition von STAT-1

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976835A (en) * 1992-03-19 1999-11-02 The Rockefeller University Nucleic acids encoding receptor recognition factor Stat1α and Stat1β, and methods of use thereof
DE69429608T2 (de) 1993-08-26 2002-09-12 Novimmune Sa, Genf/Geneve MHC-Klasse-II Transaktivator (CIITA) und dessen Anwendungen
US5463023A (en) * 1993-10-22 1995-10-31 Washington University Composition for inhibition of intracellular transcription
JPH09511908A (ja) * 1994-04-14 1997-12-02 リガンド・ファーマシューティカルズ・インコーポレイテッド サイトカインに応答性のｄｎａ調節要素
US5814517A (en) * 1994-04-14 1998-09-29 Ligand Pharmaceuticals, Inc. DNA spacer regulatory elements responsive to cytokines and methods for their use
US5707803A (en) * 1994-04-14 1998-01-13 Ligand Pharmaceuticals, Inc. DNA regulatory elements responsive to cytokines and methods for their use
AU2285995A (en) * 1994-04-14 1995-11-10 Ligand Pharmaceuticals Incorporated Dna spacer regulatory elements responsive to cytokines and methods for their use
US5672473A (en) 1994-08-24 1997-09-30 President And Fellows Of Harvard College Methods of identifying compounds useful for treating autoimmune diseases
US5643726A (en) * 1994-11-10 1997-07-01 The General Hospital Corporation Methods for modulating transcription from the amyloid β-protein precursor (APP) promoter
US5716622A (en) * 1995-01-06 1998-02-10 The Rockefeller University Functionally active regions of signal transducer and activators of transcription
US5821053A (en) * 1995-02-10 1998-10-13 Center For Blood Research, Inc. LIL-Stat DNA binding sites and methods for identifying inhibitory binding agents
GB9513342D0 (en) * 1995-06-30 1995-09-06 Medical Res Council Complexes
ZA97476B (en) * 1996-01-22 1998-07-21 Res Dev Foundation Novel methods for the characterization of compounds which stimulate STF-1 expression in pancreatic islet cells.
FR2762327B1 (fr) * 1997-04-22 1999-07-02 Transgene Sa Sequence d'acide nucleique de genes ciita, susceptibles d'etre impliquees dans le controle et la regulation de l'expression de genes codant pour des molecules mhc de type ii et leur utilisation, notamment comme medicament
US6207391B1 (en) * 1998-03-31 2001-03-27 Tularik Inc. High-throughput screening assays for modulators of STAT4 and STAT6 activity
US6235873B1 (en) * 1999-07-31 2001-05-22 The Rockefeller University Constitutively active transcription factors and their uses for identifying modulators of activity including dysproliferative cellular changes

Also Published As

Publication number Publication date
EP1068310B1 (fr) 2008-04-02
WO1999042571A1 (fr) 1999-08-26
DE69938450T2 (de) 2009-05-07
US6379894B1 (en) 2002-04-30
JP2002504325A (ja) 2002-02-12
EP1068310A1 (fr) 2001-01-17
FR2775003A1 (fr) 1999-08-20
DE69938450D1 (de) 2008-05-15
WO1999042571A8 (fr) 1999-11-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase