JP2002502383A5 - - Google Patents

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Publication number
JP2002502383A5
JP2002502383A5 JP1999500129A JP50012999A JP2002502383A5 JP 2002502383 A5 JP2002502383 A5 JP 2002502383A5 JP 1999500129 A JP1999500129 A JP 1999500129A JP 50012999 A JP50012999 A JP 50012999A JP 2002502383 A5 JP2002502383 A5 JP 2002502383A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1999500129A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002502383A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/DK1998/000224 external-priority patent/WO1998054182A1/en
Publication of JP2002502383A publication Critical patent/JP2002502383A/ja
Publication of JP2002502383A5 publication Critical patent/JP2002502383A5/ja
Withdrawn legal-status Critical Current

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JP50012999A 1997-05-30 1998-05-29 ニコチンAChレセプターに於けるコリン作動性リガンドとしての9−アザビシクロ(3.3.1)ノン−2−エン及びノナン誘導体 Withdrawn JP2002502383A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK62897 1997-05-30
DK0628/97 1997-05-30
PCT/DK1998/000224 WO1998054182A1 (en) 1997-05-30 1998-05-29 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS

Publications (2)

Publication Number Publication Date
JP2002502383A JP2002502383A (ja) 2002-01-22
JP2002502383A5 true JP2002502383A5 (enExample) 2005-12-08

Family

ID=8095743

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50012999A Withdrawn JP2002502383A (ja) 1997-05-30 1998-05-29 ニコチンAChレセプターに於けるコリン作動性リガンドとしての9−アザビシクロ(3.3.1)ノン−2−エン及びノナン誘導体

Country Status (12)

Country Link
US (1) US6392045B1 (enExample)
EP (1) EP0984966B1 (enExample)
JP (1) JP2002502383A (enExample)
CN (1) CN1205210C (enExample)
AT (1) ATE231861T1 (enExample)
AU (1) AU736798B2 (enExample)
CA (1) CA2289570C (enExample)
DE (1) DE69811070T2 (enExample)
DK (1) DK0984966T3 (enExample)
NZ (1) NZ500645A (enExample)
WO (1) WO1998054182A1 (enExample)
ZA (1) ZA984640B (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1149095B1 (en) * 1999-01-28 2004-01-21 Neurosearch A/S Novel azabicyclo derivatives and their use
EP1147112B1 (en) * 1999-01-29 2003-10-29 Abbott Laboratories Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands
US7265115B2 (en) 1999-01-29 2007-09-04 Abbott Laboratories Diazabicyclic CNS active agents
NZ513575A (en) * 1999-05-04 2003-07-25 Neurosearch As Heteroaryl diazabicycloalkanes useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators
MXPA02005884A (es) * 1999-12-14 2002-10-23 Neurosearch As Heteroaril-diazabicicloalcanos novedosos.
MY145722A (en) * 2000-04-27 2012-03-30 Abbott Lab Diazabicyclic central nervous system active agents
EP1289996B1 (en) 2000-05-25 2005-04-06 Targacept, Inc. Heteroaryldiazabicycloalkanes as nicotinic cholinergic receptor ligands
WO2001091925A1 (en) * 2000-05-31 2001-12-06 Board Of Control Of Michigan Technological University Compositions and methods for wood preservation
ATE287888T1 (de) * 2000-07-04 2005-02-15 Neurosearch As Aryl- und heteroaryldiazabicycloalkane, deren zubereitung und verwendung
US6579878B1 (en) 2000-07-07 2003-06-17 Targacept, Inc. Pharmaceutical compositions and methods for use
US6624167B1 (en) 2000-08-04 2003-09-23 Targacept, Inc. Pharmaceutical compositions and methods for use
EP1358177B1 (en) * 2000-10-13 2006-08-02 NeuroSearch A/S Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance
ATE289310T1 (de) * 2001-06-01 2005-03-15 Neurosearch As Heteroaryl-diazabicycloalkanderivaten als cns- modulatoren
ATE378048T1 (de) † 2002-12-06 2007-11-15 The Feinstein Inst Medical Res Hemmung von entzündungen unter verwendungvon alpha-7-rezeptor verbindenden cholinergen agonisten
US7238715B2 (en) 2002-12-06 2007-07-03 The Feinstein Institute For Medical Research Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
US20070191815A1 (en) 2004-09-13 2007-08-16 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
DE602006019561D1 (de) 2005-02-16 2011-02-24 Neurosearch As Diazabicyclische arylderivate und ihre verwendung als chinolinergische liganden an nikotin-acetylcholin-rezeptoren
US8316104B2 (en) 2005-11-15 2012-11-20 California Institute Of Technology Method and apparatus for collaborative system
CA2632642A1 (en) 2005-12-06 2007-06-14 Neurosearch A/S Novel diazabicyclic aryl derivatives and their medical use
EP1984365A1 (en) 2006-02-10 2008-10-29 NeuroSearch A/S 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2007090887A1 (en) * 2006-02-10 2007-08-16 Neurosearch A/S 3, 9-diazabicyclo [3.3. 1]nonane derivatives and their use as monoamine?neurotransmitter re-uptake inhibitors
US7687523B2 (en) 2006-02-10 2010-03-30 Neurosearch A/S 3-heteroaryl-3,9-diazabicyclo[3.3.1]nonane derivatives as nicotinic acetylcholine receptor agonists
WO2007093601A1 (en) 2006-02-14 2007-08-23 Neurosearch A/S 3, 9-diazabicyclo(3.3.1)non-3-yl-aryl methanone derivatives as nicotinic acetylcholine receptor agonists
TW200845977A (en) * 2007-03-30 2008-12-01 Targacept Inc Sub-type selective azabicycloalkane derivatives
EP1977746B8 (en) 2007-04-02 2014-09-24 Parkinson's Institute Methods and compositions for reduction of side effects of therapeutic treatments
US8697722B2 (en) 2007-11-02 2014-04-15 Sri International Nicotinic acetylcholine receptor modulators
WO2009058120A1 (en) * 2007-11-02 2009-05-07 Sri International Nicotinic acetylcholine receptor modulators
US20110142758A1 (en) * 2008-06-10 2011-06-16 Neurosearch A/S Indolyl-pyridazinyl-diazabicyclononane derivatives in labelled and unlabelled form and their use in diagnostic methods
JP5421368B2 (ja) 2008-08-01 2014-02-19 パーデュー、ファーマ、リミテッド、パートナーシップ テトラヒドロピリジニルおよびジヒドロピロリル化合物およびそれらの使用
WO2011085389A1 (en) 2010-01-11 2011-07-14 Astraea Therapeutics, Llc Nicotinic acetylcholine receptor modulators
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 薬剤送達方法及びシステム
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
JP2022507660A (ja) 2018-11-16 2022-01-18 モーニングサイド ベンチャー インベストメンツ リミテッド 温度によって調節される経皮薬剤送達システム

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133073A (en) * 1959-12-10 1964-05-12 Sterling Drug Inc 3-aryl-1, 5-iminocycloalkanes and preparation thereof
DE1174793B (de) * 1962-11-13 1964-07-30 Boehringer & Soehne Gmbh Verfahren zur Herstellung von 3ª‡-Phenyl-granatanen und ihren Hydrohalogeniden
US3509161A (en) * 1967-07-10 1970-04-28 Boehringer & Soehne Gmbh 3-phenyl-granatene-(2)-derivatives
IL59004A0 (en) 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
EP0093488A3 (en) 1982-03-18 1984-05-23 Beecham Group Plc Nortropyl benzopyrrolinone compounds, process for their preparation and pharmaceutical compositions containing them
JP3153551B2 (ja) * 1991-05-29 2001-04-09 アボツト・ラボラトリーズ 認識機能を高めるイソオキサゾールおよびイソチアゾール化合物
EP0853621A1 (en) * 1995-09-22 1998-07-22 Novo Nordisk A/S Novel substituted azacyclic or azabicyclic compounds
TW370451B (en) * 1996-11-26 1999-09-21 Zeneca Ltd Bicyclic amine derivatives

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