JP2002501376A5 - - Google Patents

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Publication number
JP2002501376A5
JP2002501376A5 JP1998543635A JP54363598A JP2002501376A5 JP 2002501376 A5 JP2002501376 A5 JP 2002501376A5 JP 1998543635 A JP1998543635 A JP 1998543635A JP 54363598 A JP54363598 A JP 54363598A JP 2002501376 A5 JP2002501376 A5 JP 2002501376A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998543635A
Other languages
English (en)
Japanese (ja)
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JP4271735B2 (ja
JP2002501376A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB1998/001102 external-priority patent/WO1998046743A1/en
Publication of JP2002501376A publication Critical patent/JP2002501376A/ja
Publication of JP2002501376A5 publication Critical patent/JP2002501376A5/ja
Application granted granted Critical
Publication of JP4271735B2 publication Critical patent/JP4271735B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP54363598A 1997-04-15 1998-04-15 新規のldl−レセプター Expired - Lifetime JP4271735B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4355397P 1997-04-15 1997-04-15
US60/043,553 1997-04-15
US4874097P 1997-06-05 1997-06-05
US60/048,740 1997-06-05
PCT/GB1998/001102 WO1998046743A1 (en) 1997-04-15 1998-04-15 Novel ldl-receptor

Publications (3)

Publication Number Publication Date
JP2002501376A JP2002501376A (ja) 2002-01-15
JP2002501376A5 true JP2002501376A5 (https=) 2005-11-24
JP4271735B2 JP4271735B2 (ja) 2009-06-03

Family

ID=26720554

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54363598A Expired - Lifetime JP4271735B2 (ja) 1997-04-15 1998-04-15 新規のldl−レセプター

Country Status (9)

Country Link
US (1) US6545137B1 (https=)
EP (1) EP0988379B1 (https=)
JP (1) JP4271735B2 (https=)
AT (1) ATE359367T1 (https=)
AU (1) AU733722B2 (https=)
CA (1) CA2286313C (https=)
DE (1) DE69837542T2 (https=)
ES (1) ES2285767T3 (https=)
WO (1) WO1998046743A1 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244577B2 (en) * 1997-04-15 2007-07-17 Merck & Co., Inc. Method of screening for modulator of LRP5 activity
US6770461B1 (en) 1998-10-23 2004-08-03 Genome Therapeutics Corporation High bone mass gene of 11q13.3
US6780609B1 (en) * 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6699466B1 (en) * 1999-08-05 2004-03-02 Research Corporation Technologies, Inc. IL-16 antagonist peptides and DNA encoding the peptides
FR2798138B1 (fr) * 1999-09-03 2004-05-21 Centre Nat Rech Scient Clonage, expression et caracterisation du gene spg4 responsable de la forme la plus frequente de paraplegie spastique autosomique dominante
IL151904A0 (en) * 2000-04-05 2003-04-10 Genome Therapeutics Corp THE HIGH BONE MASS GENE OF 11q13.3
CA2410253C (en) * 2000-05-26 2010-06-15 Genome Therapeutics Corporation Regulating lipid levels via the zmax1 or hbm gene
US7186515B1 (en) 2000-06-02 2007-03-06 University Of Connecticut Health Center Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof
US7449557B2 (en) 2000-06-02 2008-11-11 University Of Connecticut Health Center Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
US7179462B2 (en) 2000-06-02 2007-02-20 University Of Connecticut Health Center α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof
AU2001295010A1 (en) * 2000-08-18 2002-03-04 Case Western Reserve University Regulator gene and system useful for the diagnosis and therapy of osteoporosis
EP1434783A4 (en) * 2001-03-16 2006-06-07 Lilly Co Eli LP-mammalian proteins; RELATED REAGENTS
JP2004537289A (ja) 2001-05-11 2004-12-16 ゲノム セラピューティックス コーポレーション 骨量および脂質レベルを調整するhbm変異型
US20040221326A1 (en) * 2001-05-11 2004-11-04 Philip Babij Transgenic animal model of bone mass modulation
US7514594B2 (en) * 2001-05-11 2009-04-07 Wyeth Transgenic animal model of bone mass modulation
IL158750A0 (en) * 2001-05-17 2004-05-12 Genome Therapeutics Corp Reagents and methods for modulating dkk-mediated interactions
US20040038860A1 (en) 2002-05-17 2004-02-26 Allen Kristina M. Reagents and methods for modulating dkk-mediated interactions
HK1079705A1 (zh) 2001-08-20 2006-04-13 University Of Connecticut Health Center 包含用於治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法
GB2381790A (en) * 2001-09-26 2003-05-14 Glaxo Group Ltd LDL-receptor polypeptides
JP2005220022A (ja) * 2002-03-08 2005-08-18 Anges Mg Inc Wntの新規作用、及び、疾患治療への応用
US7169559B2 (en) * 2002-05-13 2007-01-30 Fonterra Corporate Research and Development Ltd. LDL receptor-related proteins 1 and 2 and treatment of bone or cartilage conditions
US20030219793A1 (en) * 2002-10-04 2003-11-27 Carulli John P. High bone mass gene of 11q13.3
WO2005049640A2 (en) 2003-11-17 2005-06-02 Merck & Co., Inc. Rhesus monkey dickkopf-1, nucleotides encoding same, and uses thereof
WO2005049797A2 (en) 2003-11-17 2005-06-02 Merck & Co., Inc. Cynomolgus monkey dickkopf-4, nucleotides encoding same, and uses thereof
WO2005048913A2 (en) * 2003-11-24 2005-06-02 Gunnar Westin Mutant lrp5/6 wnt-signaling receptors in cancer diagnosis, prognosis and treatment
EP4234698A3 (en) 2010-05-06 2023-11-08 Novartis AG Compositions and methods of use for therapeutic low density lipoprotein-related protein 6 (lrp6) antibodies
KR20130066631A (ko) 2010-05-06 2013-06-20 노파르티스 아게 치료적 저밀도 지단백질-관련 단백질 6 (lrp6) 다가 항체에 대한 조성물 및 사용 방법
CN104039830A (zh) 2011-11-04 2014-09-10 诺华股份有限公司 低密度脂蛋白相关蛋白6(lrp6)-半寿期延长物构建体
PL3630816T3 (pl) 2017-05-31 2024-08-05 Boehringer Ingelheim International Gmbh Polipeptydy antagonizujące sygnalizację wnt w komórkach nowotworowych

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5635177A (en) * 1992-01-22 1997-06-03 Genentech, Inc. Protein tyrosine kinase agonist antibodies
AU1173995A (en) * 1993-11-10 1995-05-29 Arch Development Corporation Ubiquitous nuclear receptor: compositions and methods
WO1995030774A1 (en) 1994-05-05 1995-11-16 Beckman Instruments, Inc. Oligonucleotide repeat arrays
JPH11508263A (ja) * 1995-06-23 1999-07-21 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ,アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ アグーチシグナルタンパク質およびそのペプチドの脱色活性
IL151904A0 (en) 2000-04-05 2003-04-10 Genome Therapeutics Corp THE HIGH BONE MASS GENE OF 11q13.3

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