JP2002501376A5 - - Google Patents

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Publication number
JP2002501376A5
JP2002501376A5 JP1998543635A JP54363598A JP2002501376A5 JP 2002501376 A5 JP2002501376 A5 JP 2002501376A5 JP 1998543635 A JP1998543635 A JP 1998543635A JP 54363598 A JP54363598 A JP 54363598A JP 2002501376 A5 JP2002501376 A5 JP 2002501376A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998543635A
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English (en)
Japanese (ja)
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JP4271735B2 (ja
JP2002501376A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB1998/001102 external-priority patent/WO1998046743A1/en
Publication of JP2002501376A publication Critical patent/JP2002501376A/ja
Publication of JP2002501376A5 publication Critical patent/JP2002501376A5/ja
Application granted granted Critical
Publication of JP4271735B2 publication Critical patent/JP4271735B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP54363598A 1997-04-15 1998-04-15 新規のldl−レセプター Expired - Lifetime JP4271735B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4355397P 1997-04-15 1997-04-15
US60/043,553 1997-04-15
US4874097P 1997-06-05 1997-06-05
US60/048,740 1997-06-05
PCT/GB1998/001102 WO1998046743A1 (en) 1997-04-15 1998-04-15 Novel ldl-receptor

Publications (3)

Publication Number Publication Date
JP2002501376A JP2002501376A (ja) 2002-01-15
JP2002501376A5 true JP2002501376A5 (https=) 2005-11-24
JP4271735B2 JP4271735B2 (ja) 2009-06-03

Family

ID=26720554

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54363598A Expired - Lifetime JP4271735B2 (ja) 1997-04-15 1998-04-15 新規のldl−レセプター

Country Status (9)

Country Link
US (1) US6545137B1 (https=)
EP (1) EP0988379B1 (https=)
JP (1) JP4271735B2 (https=)
AT (1) ATE359367T1 (https=)
AU (1) AU733722B2 (https=)
CA (1) CA2286313C (https=)
DE (1) DE69837542T2 (https=)
ES (1) ES2285767T3 (https=)
WO (1) WO1998046743A1 (https=)

Families Citing this family (29)

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US7244577B2 (en) * 1997-04-15 2007-07-17 Merck & Co., Inc. Method of screening for modulator of LRP5 activity
US6770461B1 (en) 1998-10-23 2004-08-03 Genome Therapeutics Corporation High bone mass gene of 11q13.3
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6699466B1 (en) * 1999-08-05 2004-03-02 Research Corporation Technologies, Inc. IL-16 antagonist peptides and DNA encoding the peptides
FR2798138B1 (fr) * 1999-09-03 2004-05-21 Centre Nat Rech Scient Clonage, expression et caracterisation du gene spg4 responsable de la forme la plus frequente de paraplegie spastique autosomique dominante
IL151904A0 (en) * 2000-04-05 2003-04-10 Genome Therapeutics Corp THE HIGH BONE MASS GENE OF 11q13.3
DE60129433T2 (de) * 2000-05-26 2008-04-17 Oscient Pharmaceuticals Corp., Waltham Regulation des lipidniveaus über die gene zmax1 oder hbm
US7179462B2 (en) 2000-06-02 2007-02-20 University Of Connecticut Health Center α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof
US7186515B1 (en) 2000-06-02 2007-03-06 University Of Connecticut Health Center Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof
EP1286693A4 (en) 2000-06-02 2005-07-13 Univ Connecticut Health Ct COMPLEXES OF ALPHA (2) MACROGLOBULIN AND ANTIGENIC MOLECULES FOR USE IN IMMUNOTHERAPY
EP1313753A4 (en) * 2000-08-18 2004-09-15 Proskelia REGULATORY GENE AND SYSTEM FOR USE IN THE DIAGNOSIS AND TREATMENT OF OSTEOPOROSIS
WO2002074906A2 (en) * 2001-03-16 2002-09-26 Eli Lilly And Company Lp mammalian proteins; related reagents
US20040221326A1 (en) * 2001-05-11 2004-11-04 Philip Babij Transgenic animal model of bone mass modulation
WO2002092000A2 (en) 2001-05-11 2002-11-21 Genome Therapeutics Corporation Hbm variants that modulate bone mass and lipid levels
US7514594B2 (en) * 2001-05-11 2009-04-07 Wyeth Transgenic animal model of bone mass modulation
US20040038860A1 (en) 2002-05-17 2004-02-26 Allen Kristina M. Reagents and methods for modulating dkk-mediated interactions
JP2005512508A (ja) * 2001-05-17 2005-05-12 ゲノム セラピューティックス コーポレーション Dkk媒介性相互作用を変調する試薬および方法
CN1635896A (zh) 2001-08-20 2005-07-06 康涅狄格大学健康中心 包含用于治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法
GB2381790A (en) * 2001-09-26 2003-05-14 Glaxo Group Ltd LDL-receptor polypeptides
JP2005220022A (ja) * 2002-03-08 2005-08-18 Anges Mg Inc Wntの新規作用、及び、疾患治療への応用
US7169559B2 (en) * 2002-05-13 2007-01-30 Fonterra Corporate Research and Development Ltd. LDL receptor-related proteins 1 and 2 and treatment of bone or cartilage conditions
US20030219793A1 (en) * 2002-10-04 2003-11-27 Carulli John P. High bone mass gene of 11q13.3
WO2005049797A2 (en) 2003-11-17 2005-06-02 Merck & Co., Inc. Cynomolgus monkey dickkopf-4, nucleotides encoding same, and uses thereof
US7622553B2 (en) 2003-11-17 2009-11-24 Merck & Co., Inc. Rhesus monkey dickkopf-1, nucleotides encoding same, and uses thereof
WO2005048913A2 (en) * 2003-11-24 2005-06-02 Gunnar Westin Mutant lrp5/6 wnt-signaling receptors in cancer diagnosis, prognosis and treatment
EP2566892B1 (en) 2010-05-06 2017-12-20 Novartis AG Compositions and methods of use for therapeutic low density lipoprotein-related protein 6 (lrp6) antibodies
PH12012502193A1 (en) 2010-05-06 2021-08-09 Novartis Ag Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
ES2666856T3 (es) 2011-11-04 2018-05-08 Novartis Ag Proteína 6 relacionada con lipoproteínas de baja densidad (LRP6) - constructos extensores de la vida media
EP3630816B1 (en) 2017-05-31 2024-03-20 Boehringer Ingelheim International GmbH Polypeptides antagonizing wnt signaling in tumor cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5635177A (en) * 1992-01-22 1997-06-03 Genentech, Inc. Protein tyrosine kinase agonist antibodies
AU1173995A (en) * 1993-11-10 1995-05-29 Arch Development Corporation Ubiquitous nuclear receptor: compositions and methods
EP0758403B1 (en) * 1994-05-05 1998-06-24 Beckman Instruments, Inc. Oligonucleotide repeat arrays
ES2169804T3 (es) * 1995-06-23 2002-07-16 Us Gov Health & Human Serv Actividad despigmentante de la proteina señal aguti y peptidos de la misma.
IL151904A0 (en) 2000-04-05 2003-04-10 Genome Therapeutics Corp THE HIGH BONE MASS GENE OF 11q13.3

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