JP2002500618A5 - - Google Patents

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Publication number
JP2002500618A5
JP2002500618A5 JP1997525183A JP52518397A JP2002500618A5 JP 2002500618 A5 JP2002500618 A5 JP 2002500618A5 JP 1997525183 A JP1997525183 A JP 1997525183A JP 52518397 A JP52518397 A JP 52518397A JP 2002500618 A5 JP2002500618 A5 JP 2002500618A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1997525183A
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English (en)
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JP2002500618A (ja
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Priority claimed from PCT/US1996/017995 external-priority patent/WO1997025033A1/en
Publication of JP2002500618A publication Critical patent/JP2002500618A/ja
Publication of JP2002500618A5 publication Critical patent/JP2002500618A5/ja
Withdrawn legal-status Critical Current

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Figure 2002500618
Figure 2002500618
Figure 2002500618
Figure 2002500618
JP52518397A 1995-10-31 1996-10-30 抗血栓性ジアミン Withdrawn JP2002500618A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US712095P 1995-10-31 1995-10-31
US2825296P 1996-10-09 1996-10-09
US60/007,120 1996-10-09
US60/028,252 1996-10-09
PCT/US1996/017995 WO1997025033A1 (en) 1995-10-31 1996-10-30 Antithrombotic diamines

Publications (2)

Publication Number Publication Date
JP2002500618A JP2002500618A (ja) 2002-01-08
JP2002500618A5 true JP2002500618A5 (ja) 2004-10-28

Family

ID=26676549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52518397A Withdrawn JP2002500618A (ja) 1995-10-31 1996-10-30 抗血栓性ジアミン

Country Status (9)

Country Link
US (3) US6025382A (ja)
EP (1) EP0863755B1 (ja)
JP (1) JP2002500618A (ja)
AT (1) ATE284690T1 (ja)
AU (1) AU7725596A (ja)
CA (1) CA2236007A1 (ja)
DE (1) DE69634045T2 (ja)
ES (1) ES2233982T3 (ja)
WO (1) WO1997025033A1 (ja)

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WO1998049160A1 (en) * 1997-04-30 1998-11-05 Eli Lilly And Company Antithrombotic agents
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AU7170798A (en) 1997-04-30 1998-11-24 Eli Lilly And Company Antithrombotic agents
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US6017914A (en) * 1997-09-03 2000-01-25 Eli Lilly And Company Benzo[b]thiophene compounds, intermediates, formulations, and methods
US6284756B1 (en) 1998-04-30 2001-09-04 Eli Lilly And Company Antithrombotic agents
US6166069A (en) * 1998-05-12 2000-12-26 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
ES2189355T3 (es) * 1998-10-28 2003-07-01 Lilly Co Eli Compuestos de benzotiofeno como agentes antitromboticos e intermedios.
ATE258934T1 (de) 1998-10-30 2004-02-15 Lilly Co Eli Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe
US6620837B1 (en) * 1999-11-19 2003-09-16 Eli Lilly And Company Antithrombotic agents
ES2236536T3 (es) 2001-05-22 2005-07-16 Eli Lilly And Company Derivados tetrahidroquinolino para la inhibicion de enfermedades asociadas con la privacion de estrogenos o con una respuesta fisiologica aberrante a estrogenos endogenos.
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US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
AU2002351412B2 (en) 2001-12-21 2010-05-20 Exelixis Patent Company Llc Modulators of LXR
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ES2844401T3 (es) 2003-08-01 2021-07-22 Mitsubishi Tanabe Pharma Corp Compuestos novedosos que tienen actividad inhibidora frente a transportador de glucosa dependiente de sodio
US8785403B2 (en) 2003-08-01 2014-07-22 Mitsubishi Tanabe Pharma Corporation Glucopyranoside compound
NZ556686A (en) 2005-02-14 2010-01-29 Bionomics Ltd Novel tubulin polymerisation inhibitors
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
UY30730A1 (es) 2006-12-04 2008-07-03 Mitsubishi Tanabe Pharma Corp Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
CA2699285C (en) 2007-09-10 2016-12-13 Ahmed F. Abdel-Magid Process for the preparation of compounds useful as inhibitors of sodium-dependent glucose transporter (sglt)
CL2008003653A1 (es) 2008-01-17 2010-03-05 Mitsubishi Tanabe Pharma Corp Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
US9056850B2 (en) 2008-10-17 2015-06-16 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
CN102648196B (zh) 2009-10-14 2016-04-27 詹森药业有限公司 可用作sglt2的抑制剂的化合物的制备方法
JP6227406B2 (ja) 2010-05-11 2017-11-08 ヤンセン ファーマシューティカ エヌ．ベー． ＳＧＬＴの阻害剤としての１−（β−Ｄ−グルコピラノシル）−２−チエニル−メチルベンゼン誘導体を含有する医薬製剤
WO2012140120A1 (en) 2011-04-13 2012-10-18 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of sglt2
US9035044B2 (en) 2011-05-09 2015-05-19 Janssen Pharmaceutica Nv L-proline and citric acid co-crystals of (2S, 3R, 4R, 5S,6R)-2-(3-((5-(4-fluorophenyl)thiopen-2-yl)methyl)4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
CN104159900B (zh) 2011-12-15 2016-08-24 拜耳知识产权有限责任公司 取代的苯并噻吩基-吡咯并三嗪及其在癌症治疗中的用途
CA2865021C (en) 2012-02-23 2020-06-30 Bayer Intellectual Property Gmbh Substituted benzothienyl-pyrrolotriazines and uses thereof
CN107207459B (zh) * 2015-02-19 2021-03-30 捷恩智株式会社 具有苯并噻吩的液晶性化合物、液晶组合物及液晶显示元件
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
CA3026784A1 (en) 2016-06-07 2017-12-14 Jacobio Pharmaceuticals Co., Ltd. Heterocyclic pyrazine derivatives useful as shp2 inhibitors
WO2018172984A1 (en) 2017-03-23 2018-09-27 Jacobio Pharmaceuticals Co., Ltd. Novel heterocyclic derivatives useful as shp2 inhibitors

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US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
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US5510357A (en) * 1995-02-28 1996-04-23 Eli Lilly And Company Benzothiophene compounds as anti-estrogenic agents
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US5929090A (en) 1997-09-12 1999-07-27 Eli Lilly And Company 2-aryl-3-aminoaryloxynaphthy1 compounds, intermediates, compositions and methods

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