JP2002500514A5 - - Google Patents

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Publication number
JP2002500514A5
JP2002500514A5 JP1999500386A JP50038699A JP2002500514A5 JP 2002500514 A5 JP2002500514 A5 JP 2002500514A5 JP 1999500386 A JP1999500386 A JP 1999500386A JP 50038699 A JP50038699 A JP 50038699A JP 2002500514 A5 JP2002500514 A5 JP 2002500514A5
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JP
Japan
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JP1999500386A
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English (en)
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JP4060892B2 (ja
JP2002500514A (ja
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Priority claimed from GBGB9710829.4A external-priority patent/GB9710829D0/en
Priority claimed from GBGB9724850.4A external-priority patent/GB9724850D0/en
Priority claimed from GBGB9804195.7A external-priority patent/GB9804195D0/en
Application filed filed Critical
Priority claimed from PCT/GB1998/001564 external-priority patent/WO1998054312A1/en
Publication of JP2002500514A publication Critical patent/JP2002500514A/ja
Publication of JP2002500514A5 publication Critical patent/JP2002500514A5/ja
Application granted granted Critical
Publication of JP4060892B2 publication Critical patent/JP4060892B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Description

Figure 2002500514
Figure 2002500514
Figure 2002500514
Figure 2002500514
Figure 2002500514
Figure 2002500514
JP50038699A 1997-05-28 1998-05-28 タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体 Expired - Fee Related JP4060892B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9710829.4A GB9710829D0 (en) 1997-05-28 1997-05-28 Selection particles for in vitro display and evolution of antibody combining sites
GB9710829.4 1997-05-28
GBGB9724850.4A GB9724850D0 (en) 1997-11-26 1997-11-26 Selection particles for in vitro display and evolution of antibody combining sites
GB9724850.4 1997-11-26
GBGB9804195.7A GB9804195D0 (en) 1998-02-28 1998-02-28 Selection particles for in vitro display and evolution of antibody combining sites
GB9804195.7 1998-02-28
PCT/GB1998/001564 WO1998054312A1 (en) 1997-05-28 1998-05-28 Ribosome complexes as selection particles for in vitro display and evolution of proteins

Publications (3)

Publication Number Publication Date
JP2002500514A JP2002500514A (ja) 2002-01-08
JP2002500514A5 true JP2002500514A5 (ja) 2005-12-08
JP4060892B2 JP4060892B2 (ja) 2008-03-12

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ID=27268863

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50038699A Expired - Fee Related JP4060892B2 (ja) 1997-05-28 1998-05-28 タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体

Country Status (10)

Country Link
US (1) US6620587B1 (ja)
EP (1) EP0985032B2 (ja)
JP (1) JP4060892B2 (ja)
AT (1) ATE250668T1 (ja)
CA (1) CA2291721C (ja)
DE (1) DE69818458T3 (ja)
DK (1) DK0985032T4 (ja)
ES (1) ES2209145T5 (ja)
PT (1) PT985032E (ja)
WO (1) WO1998054312A1 (ja)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000001849A1 (en) * 1998-07-02 2000-01-13 Invitro Diagnostics, Inc. Methods, compositions and apparatus for making nucleic acid molecules having a selected affinity to a target molecule
DE19932688B4 (de) 1999-07-13 2009-10-08 Scil Proteins Gmbh Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
GB9917027D0 (en) * 1999-07-20 1999-09-22 Affibody Technology Sweeden Ab In vitro selection and optional identification of polypeptides using solid support carriers
IL150291A0 (en) * 2000-01-11 2002-12-01 Maxygen Inc Integrated systems and methods for diversity generation and screening
AU2001239444B2 (en) * 2000-03-31 2004-10-07 Cambridge Antibody Technology Limited Improvements to ribosome display
EP1652919A1 (en) * 2000-03-31 2006-05-03 Cambridge Antibody Technology LTD Improvements to ribosome display
US7129326B2 (en) 2000-04-14 2006-10-31 Genencor International, Inc. Methods for selective targeting
EP1360500B1 (en) 2000-04-14 2010-01-13 Genencor International, Inc. Methods for selective targeting
JP4295513B2 (ja) 2001-03-07 2009-07-15 チルドレンズ メディカル センター コーポレーション ミニ細胞ディスプレイを用いるペプチドディスプレイライブラリーをスクリーニングする方法
US20060234231A1 (en) * 2001-06-20 2006-10-19 Nuevolution A/S Microarrays displaying encoded molecules
EP1401850A1 (en) 2001-06-20 2004-03-31 Nuevolution A/S Nucleoside derivatives for library preparation
DE10145226A1 (de) * 2001-09-13 2003-04-10 Lifebits Ag Herstellung von trägergebundenen Molekülen
DE10147074A1 (de) * 2001-09-25 2003-05-08 Beru Ag Verfahren zum Betreiben einer aus mehreren Heizelementen bestehenden mehrstufigen elektrischen Heizung
DE20200926U1 (de) * 2002-01-23 2002-04-18 Hegenscheidt Mfd Gmbh & Co Kg Festwalzgerät einer Festwalzmaschine für Kurbelwellen
EP2186897B1 (en) 2002-03-15 2016-02-17 Nuevolution A/S An improved method for synthesising templated molecules
US20050176948A1 (en) * 2002-03-15 2005-08-11 Gouliaev Alex H. Building block capable of functional entity transfer to nucleophil
WO2003078050A2 (en) * 2002-03-15 2003-09-25 Nuevolution A/S A building block forming a c-c bond upon reaction
EP1487850A2 (en) * 2002-03-15 2004-12-22 Nuevolution A/S A building block forming a c-c or a c-hetero atom bond upon reaction
WO2004013070A2 (en) * 2002-08-01 2004-02-12 Nuevolution A/S Multi-step synthesis of templated molecules
US7842476B2 (en) * 2002-09-06 2010-11-30 Isogenica Limited In vitro peptide expression library
CN106337046B (zh) * 2002-10-30 2021-03-23 纽韦卢森公司 合成双功能复合物的方法
US20060171885A1 (en) 2002-11-25 2006-08-03 Giselle Janssen Skin or hair binding peptides
US9121110B2 (en) * 2002-12-19 2015-09-01 Nuevolution A/S Quasirandom structure and function guided synthesis methods
US20060269920A1 (en) * 2003-02-21 2006-11-30 Nuevolution A/S Method for obtaining structural information about an encoded molecule
EP1597395A2 (en) 2003-02-21 2005-11-23 Nuevolution A/S Method for producing second-generation library
WO2004083461A1 (en) * 2003-03-19 2004-09-30 Discerna Limited Recovery of dna
DE602004019764D1 (de) * 2003-03-20 2009-04-16 Nuevolution As Ligationsvermittelnde codierung von kleinen molekülen
DE10324447A1 (de) 2003-05-28 2004-12-30 Scil Proteins Gmbh Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin
GB0316314D0 (en) * 2003-07-12 2003-08-13 Univ Belfast Method
WO2005026387A1 (en) * 2003-09-18 2005-03-24 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
EP1723255B1 (en) * 2004-02-17 2010-12-29 Nuevolution A/S Method for enrichment involving elimination by mismatch hybridisation
DE602005017370D1 (de) * 2004-03-22 2009-12-10 Nuevolution As Ligationscodierung unter verwendung von oligonukleotidbausteinen
US20050250112A1 (en) * 2004-05-07 2005-11-10 Padmabandu Gothami A Nucleic acids, compositions, methods, and kits for detecting mycoplasma and acholeplasma species
US9006393B1 (en) 2004-08-26 2015-04-14 Patricia L. Clark Molecular constructs and uses thereof in ribosomal translational events
DE102004049479A1 (de) 2004-10-11 2006-04-13 Scil Proteins Gmbh Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie
ATE490318T1 (de) 2005-12-01 2010-12-15 Nuevolution As Enzymvermittelnde kodierungsmethoden für eine effiziente synthese von grossen bibliotheken
GB0605584D0 (en) 2006-03-20 2006-04-26 Olink Ab Method for analyte detection using proximity probes
US7879975B2 (en) * 2006-06-29 2011-02-01 The Invention Science Fund I, Llc Methods for arbitrary peptide synthesis
US7923533B2 (en) * 2006-06-29 2011-04-12 The Invention Science Fund I, Llc Methods for arbitrary peptide synthesis
US7777002B2 (en) * 2006-06-29 2010-08-17 The Invention Science Fund I, Llc Methods for arbitrary peptide synthesis
US7910695B2 (en) 2006-06-29 2011-03-22 The Invention Science Fund I, Llc Methods for arbitrary peptide synthesis
US7879973B2 (en) * 2006-06-29 2011-02-01 The Invention Science Fund I, Llc Methods for arbitrary peptide synthesis
EP1925664A1 (en) 2006-11-15 2008-05-28 Scil proteins GmbH Artificial binding proteins based on a modified alpha helical region of ubiquitin
US8865179B2 (en) * 2008-01-26 2014-10-21 Swey-Shen Alexchen Aptameric IgE peptides in a protein scaffold as an allergy vaccine
CN102177438A (zh) * 2008-07-25 2011-09-07 理查德·W·瓦格纳 蛋白筛选方法
RU2011117210A (ru) * 2008-09-30 2012-11-10 Эбботт Лэборетриз (Us) Улучшенные способы рнк-дисплея
AU2010332932B2 (en) 2009-12-14 2013-01-17 Navigo Proteins Gmbh Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin
JP5863045B2 (ja) 2010-03-11 2016-02-16 国立研究開発法人理化学研究所 ポリペプチド配列の選択方法、並びに金属酸化物または含珪素化合物結合ペプチドおよびその利用
GB201004292D0 (en) 2010-03-15 2010-04-28 Olink Ab Assay for localised detection of analytes
CA2832672A1 (en) 2010-04-16 2011-10-20 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes
GB201011971D0 (en) 2010-07-15 2010-09-01 Olink Ab Methods and product
US10669569B2 (en) 2010-10-15 2020-06-02 Navinci Diagnostics Ab Dynamic range methods
EP2466310A1 (en) 2010-12-17 2012-06-20 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH Means and methods for detecting double-strand breaks
DE102010056289A1 (de) 2010-12-24 2012-06-28 Geneart Ag Verfahren zur Herstellung von Leseraster-korrekten Fragment-Bibliotheken
GB201101621D0 (en) 2011-01-31 2011-03-16 Olink Ab Method and product
JP5948673B2 (ja) 2011-03-10 2016-07-06 ジーンフロンティア株式会社 リポ多糖混入量を低減した蛋白質合成用組成物、該組成物を用いた蛋白質製造方法
GB201107863D0 (en) 2011-05-11 2011-06-22 Olink Ab Method and product
JP6057297B2 (ja) 2011-05-23 2017-01-11 国立研究開発法人理化学研究所 核酸構築物、核酸−蛋白質複合体、及びその利用
CA2837804C (en) 2011-06-15 2018-03-20 Scil Proteins Gmbh Dimeric binding proteins based on modified ubiquitins
GB201201547D0 (en) 2012-01-30 2012-03-14 Olink Ab Method and product
WO2015120058A2 (en) 2014-02-05 2015-08-13 Molecular Templates, Inc. Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
US20170306039A1 (en) * 2014-10-22 2017-10-26 Crescendo Biologics Limited Human vh domain scaffolds
US10858405B2 (en) 2015-02-06 2020-12-08 Navigo Proteins Gmbh EGFR binding proteins
US10808042B2 (en) 2015-07-16 2020-10-20 Navigo Proteins Gmbh Immunoglobulin-binding proteins and their use in affinity purification
US10584152B2 (en) 2015-07-20 2020-03-10 Navigo Proteins Gmbh Binding proteins based on di-ubiquitin muteins and methods for generation
AU2016326737B2 (en) 2015-09-24 2023-01-12 Abvitro Llc Affinity-oligonucleotide conjugates and uses thereof
WO2017191252A1 (en) 2016-05-04 2017-11-09 Navigo Proteins Gmbh Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
CA3030208A1 (en) 2016-08-11 2018-02-15 Navigo Proteins Gmbh Novel alkaline stable immunoglobulin binding proteins
JP6929354B2 (ja) 2016-09-24 2021-09-01 アブビトロ, エルエルシー 親和性−オリゴヌクレオチドコンジュゲートおよびその使用
EP3706804B1 (en) 2017-11-07 2022-02-23 Navigo Proteins GmbH Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer
KR20220044212A (ko) 2019-08-09 2022-04-06 넛크래커 테라퓨틱스 인코포레이티드 미세유체 장치 및 이의 사용 방법
EP4382534A1 (en) 2022-12-06 2024-06-12 Biomérieux Synthetic peptide for use in an immunomolecular assay

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06178688A (ja) * 1992-12-11 1994-06-28 Mitsui Toatsu Chem Inc E型緑膿菌を抗原とするヒト抗体をコードする遺伝子
WO1995011922A1 (en) 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
AU2001239444B2 (en) 2000-03-31 2004-10-07 Cambridge Antibody Technology Limited Improvements to ribosome display

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