JP2002348207A - Cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cosmetic, excellent in emulsion stability and safety for an organism, having a good sense of use, a good feeling after use, and general effects on beauty, and having the improved effect of hair quality, bleaching effect and the stable color of the skin. SOLUTION: The cosmetic is formulated with a rice obtained through fermentation by lactic acid.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic containing a processed rice product. More particularly, the present invention is useful not only as a base material for cosmetics such as an emulsifier or an emulsion stabilizer, but also as a whitening / beautifying effect. The present invention relates to a cosmetic which has an excellent cosmetic effect such as a hair quality improving effect, and which contains a processed rice product having high biosafety.

[0002]

2. Description of the Related Art Conventionally, nonionic surfactants such as polyoxyethylene alkyl ethers and sorbitan fatty acid partial esters are mainly used for emulsification in cosmetics. However, these surfactants cannot but avoid irritating action on the skin to some extent, and as a result, it has been attempted to reduce the amount of the surfactant used as much as possible and to emulsify without using these in some cases. However, there is a tendency that problems occur in terms of uniformity, stability and the like of the emulsion, and a satisfactory product has not always been obtained.

[0003] On the other hand, it has been proposed to prepare an emulsion having high safety to skin by using a component derived from a natural product such as saponin, lecithin, and enzyme-treated stevia as an emulsifier. However, there are aspects that are not always sufficient in terms of emulsification stability, usability when applied to the skin, ease of production, etc.Therefore, a new natural product-derived emulsifier that has solved them has been demanded. .

[0004] The above requirement for biosafety is not limited to emulsifiers, but is common to all components of cosmetics. Active ingredients such as whitening ingredients and skin anti-aging ingredients are also effective and effective. If we can find one that also has safety, it can be said that its usefulness is extremely high.

[Problems to be solved by the invention]

[0005] The present inventors have conducted intensive studies on compounding agents used in cosmetics, particularly emulsifiers, to provide highly safe agents using natural products as raw materials. As a result, rice was fermented with lactic acid bacteria. The obtained fermented rice has good emulsifying power and emulsifying stabilizing action or protective colloid-like action, and is derived from rice, so it has low toxicity and little irritation to the skin. It is useful as a base material such as an emulsifier or an emulsion stabilizer for ingredients, and in addition, surprisingly, the fermented rice has a remarkable whitening / beautifying effect and a hair quality improving effect. The present inventors have found that the compound is useful as a compounding agent for achieving a cosmetic effect, and completed the present invention.

[Means for Solving the Problems]

[0006] That is, the present invention is a cosmetic characterized by blending lactic acid bacteria fermented rice obtained by fermenting rice with lactic acid bacteria. The cosmetics according to the present invention include quasi-drugs in addition to so-called cosmetics.

Hereinafter, the present invention will be described in detail. Rice used for the production of lactic acid bacteria fermented rice of the present invention is brown rice, polished rice,
It may be any of processed rice etc., but there is no particular limitation,
Generally, polished or processed rice is used. Non-glutinous rice and glutinous rice can be used. Examples of processed rice include low-allergen rice, low-protein rice (for example, low glycerin rice), and fortified rice (for example, γ-aminobutyric acid rice). Can be selected and used.

[0008] Lactic acid bacteria used for fermentation of the raw rice include, for example, Lactobacillus plantarum.
lus plantarum), Lactobacillus brevis (L. brevi)
s), Lactobacillus casei (L. casei), Lactobacillus cellobiosas (L. cellobiosus), Lactobacillus basinosterus (L. vaccinostercus), Streptococcus faecalis (Streptococcus faecalis), Bacillus coagulans (Bacillus coagulans), and the like are obtained. Use of Lactobacillus plantarum is particularly preferred from the viewpoint of the emulsifying ability of lactic acid bacteria-fermented rice.

[0009] The fermentation of rice by these lactic acid bacteria is performed, for example, as follows. First, the rice is subjected to an appropriate means such as washing of rice to remove various bacteria which hinder lactic acid bacteria fermentation. The rice was immersed in purified water of 1-5 times, this carbohydrate 1-4 wt% and lactic acid ¹⁰ 7 to 10 ⁸ cells / ml was added to anaerobic conditions, of lactic acid bacteria using Fermentation is carried out for 1 to 7 days near the optimal fermentation temperature. As the saccharide, glucose, fructose, galactose, sucrose and the like are used, and among them, fructose is most preferably used.

The liquid containing lactic acid bacteria-fermented rice obtained by the above fermentation step may be subjected to a milling step as it is, and if necessary, concentrated to be blended with cosmetics. The fermented rice is separated from the fermentation liquid, washed with water, adjusted for water if necessary, ground using appropriate means such as an air-flow grinder, and dried if necessary for cosmetics. Serve as a compounding agent.

When the fermentation step is carried out in the presence of an inorganic salt such as salt during the above-mentioned steps, the resulting lactic acid bacteria-fermented rice tends to have a reduced emulsifying ability.
For example, since there is no significant decrease in the whitening / beautifying effect, hair quality improving effect, etc., when preparing lactic acid bacteria-fermented rice for the purpose of utilizing these functions, salt, etc. may be present in the fermentation liquid if necessary. There is no harm in doing so.
In addition, fermented rice obtained by fermenting lactic acid bacteria in the presence of salt,
Although the emulsifying ability tends to decrease, it has a sufficient effect on thickening and stabilizing an emulsified system or a dispersed system, so that it can be used for such purpose.

The lactic acid bacteria fermented rice obtained as described above is
As shown later in Test Examples 1 to 3, it has a good emulsifying effect and an emulsifying stabilizing effect, gives an emulsion rich in emulsifying stability, and has excellent biosafety with low toxicity and little irritation to the skin, They are useful as emulsifiers or emulsion stabilizers for cosmetics. In addition, the fermented rice has a strong inhibitory effect on intracellular tyrosinase activity (Test Example 4).
And a skin pigmentation inhibitory action based thereon (Test Example 5),
Furthermore, it has an activating effect on fibroblasts (Test Example 6), as a new whitening agent for preventing and improving pigmentation of spots, freckles, etc., as well as for skin aging prevention and skin roughening for rough skin improvement. It is also useful as an agent.

[0013] In addition, the fermented rice for lactic acid bacteria used in the present invention comprises:
It has high water retention / moisture retention and foam stabilizing effects, as well as protection and adhesion effects on hair, skin, etc.For example, when it is incorporated into cleaning cosmetics such as shampoos and rinses, its properties Based on that, when used, foaming is creamy and has a good feeling of use, while protecting and improving the hair and suppressing the occurrence of split ends and cuts, it also gives excellent moist feeling and gloss to the hair after use A product having properties can be obtained. In addition, as a result of the above-mentioned high water retention / moisturizing power of the lactic acid bacteria-fermented rice, the effect of adhesion to hair, skin, etc., the cosmetic obtained by blending the fermented rice has characteristics not found in conventional base materials. It has an appropriate and preferable feeling of use (elongation during application, smoothness, etc.) and a feeling after use (moist feeling, etc.).

When lactic acid bacteria-fermented rice is incorporated into cosmetics as an emulsifier, the fermented rice alone has a sufficient emulsifying power, and the obtained emulsion shows emulsification stability which is sufficiently satisfactory for practical use. By further using a thickener in combination with this, the stability of the emulsion can be further improved.

As the thickener, those commonly used in cosmetics can be used, and specifically, components derived from brown algae, green algae or red algae such as alginic acid, agar, carrageenan, fucoidan; Polysaccharides such as pectin and locust bean gum; xanthan gum, tragacanth gum,
Gums such as guar gum; carboxymethyl cellulose;
Cellulose derivatives such as hydroxyethylcellulose; synthetic polymers such as polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic acid / methacrylic acid copolymer; hyaluronic acid or derivatives thereof, and polyglutamic acid or derivatives thereof. Among them, the use of hyaluronic acid or a derivative thereof, polyglutamic acid or a derivative thereof, xanthan gum or tragacanth gum is particularly preferred from the viewpoint of not impairing the emulsion stability and the safety which is a feature of the fermented rice with lactic acid bacteria, and the use of alginic acid. , Agar, carrageenan, fucoidan, and other components derived from brown algae, green algae or red algae can also be suitably used.

When these thickeners are used in combination, the amount of use depends on the kind of the thickener used, but is generally from 1 to 100 parts by weight per 100 parts by weight of the solids of the lactic acid bacteria-fermented rice. Parts, preferably in the range of 5 to 50 parts by weight. From such a range, an optimum one is selected in consideration of the use of the emulsion, required performance and the like.

When used in combination with lactic acid bacteria-fermented rice, the thickener may be used by mixing it with lactic acid bacteria-fermented rice in a predetermined ratio in advance, or when emulsifying cosmetics using lactic acid bacteria-fermented rice, The rice may be added to the emulsified system before or after the addition of the rice or simultaneously with the fermented rice. In some cases, it can be added after emulsification.

Examples of the cosmetics of the present invention containing lactic acid bacteria-fermented rice include, for example, basic cosmetics such as emulsions, creams, lotions, essences and packs; makeup cosmetics such as lipsticks, foundations, liquid foundations, and makeup press powders. Cleansing cosmetics such as facial cleansers, shampoos, and rinses; hair cosmetics such as hair treatments, conditioners, hair creams, hair dyes, and hair styling products; oral cosmetics such as toothpastes and mouthwashes; Examples include foreign goods, but are not limited to these.

The amount of the fermented rice with lactic acid bacteria in the cosmetic of the present invention varies depending on the purpose of blending the fermented rice, the type of the cosmetic, and the like. For cosmetics, make-up cosmetics, hair cosmetics and quasi-drugs, generally 0.5 to 20
% By weight (as the solid content of lactic acid bacteria-fermented rice; the same applies hereinafter), preferably in the range of 2 to 10% by weight, and for cleaning cosmetics, generally 1 to 30% by weight, preferably 5 to 20% by weight.
Of oral cosmetics, generally 0.5 to 20
%, Preferably in the range of 2 to 10% by weight. In this case, if a thickener is used in combination, the amount of lactic acid bacteria-fermented rice can be reduced to 40 to 80% of that in the case of using the above alone.

When the lactic acid bacteria-fermented rice of the present invention is used as an emulsifying stabilizer, the compounding amount is generally 0.1 to 20 for basic cosmetics, makeup cosmetics, hair cosmetics, oral cosmetics and quasi-drugs. % By weight, preferably 0.5
It is generally in the range of 1 to 30% by weight, preferably 5 to 20% by weight, for cleansing cosmetics.

On the other hand, the amount of lactic acid bacteria-fermented rice added to cosmetics as a skin-whitening / beautifying agent is generally 0.1% for basic cosmetics, makeup cosmetics and quasi-drugs.
1 to 10% by weight, preferably in the range of 0.5 to 5% by weight,
The amount of the bathing agent is generally in the range of 1 to 30% by weight, preferably 3 to 15% by weight.

When preparing a cosmetic containing the fermented rice with lactic acid bacteria of the present invention, the constituent components are those commonly used in cosmetics, such as oily components, surfactants, humectants, thickeners, preservatives and sterilizers. Agents, powder components, ultraviolet absorbers, antioxidants, dyes, fragrances, physiologically active components, and the like can be used or used in combination.

Here, the oily component includes, for example, olive oil, jojoba oil, castor oil, soybean oil, rice oil, rice germ oil,
Plant-derived fats and oils such as palm oil, palm oil, cocoa oil, meadowfoam oil, shea butter, tea tree oil; oils and fats derived from animals such as mink oil and turtle oil; beeswax, carnauba wax, rice wax, lanolin, etc. Waxes; hydrocarbons such as liquid paraffin, vaseline, paraffin wax, squalane; fatty acids such as myristic acid, palmitic acid, stearic acid, oleic acid, isostearic acid; lauryl alcohol, cetanol,
Higher alcohols such as stearyl alcohol; and synthetic esters such as isopropyl myristate, isopropyl palmitate, butyl oleate, 2-ethylhexyl glyceride, and higher fatty acid octyldodecyl (such as octyldodecyl stearate), and synthetic triglycerides.

When the lactic acid bacteria-fermented rice is used as an emulsifier, it is not always necessary to use the surfactant in combination. Even when the surfactant is used in combination, it is possible to use sucrose fatty acid ester, lecithin, enzyme-treated stevia and the like. Although it is preferable to use a small amount of an active agent with excellent safety, a case in which lactic acid bacteria-fermented rice is blended as an emulsifying stabilizer or a whitening / beautifying component, and part or all of the emulsification depends on an existing surfactant. Then, as such a surfactant,
In addition to the above-mentioned sucrose fatty acid ester, etc., for example, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene Nonionic surfactants such as hydrogenated castor oil and polyoxyethylene sorbitol fatty acid esters; fatty acid salts, alkyl sulfates, alkyl benzene sulfonates, polyoxyethylene alkyl ether sulfates, polyoxyethylene fatty amine sulfates, polyoxyethylene alkyls Phenyl ether sulfate, polyoxyethylene alkyl ether phosphate, α-sulfonated fatty acid alkyl ester salt, polyoxyethylene alkyl phenylate Anionic surfactants such as phosphate;
Quaternary ammonium salts, primary to tertiary fatty amine salts,
Cationic surfactants such as trialkylbenzylammonium salts, alkylpyridinium salts, 2-alkyl-1-alkyl-1-hydroxyethylimidazolinium salts, N, N-dialkylmorphonium salts, and polyethylenepolyamine fatty acid amide salts; , N-dimethyl-N-
Alkyl-N-carboxymethylammonio betaine,
N, N, N-trialkyl-N-alkyleneammoniocarboxybetaine, N-acylamidopropyl-
An amphoteric surfactant such as N ', N'-dimethyl-N'-β-hydroxypropylammoniosulfobetaine can be used.

Examples of humectants include glycerin, propylene glycol, dipropylene glycol, 1,3-
Butylene glycol, polyethylene glycol, sorbitol, xylitol, pyrrolidone carboxy sodium and the like, further saccharides, hyaluronic acid and its derivatives,
Lactic acid, urea, various amino acids and their derivatives.

Examples of the thickener include the aforementioned seaweed-derived components,
Examples include polysaccharides, gums, cellulose derivatives, hyaluronic acid and derivatives thereof.

Examples of the preservative disinfectant include urea; paraoxybenzoic acid esters such as methyl paraoxybenzoate, ethyl paraoxybenzoate, propyl paraoxybenzoate and butyl paraoxybenzoate; phenoxyethanol, dichlorophen, hexachlorophen, chlorhexidine hydrochloride, Examples include benzalkonium chloride, salicylic acid, ethanol, undecylenic acid, phenols, and jamal (imidazodinyl urea).

Examples of the powder component include sericite, titanium oxide, talc, kaolin, bentonite, zinc oxide, magnesium carbonate, magnesium oxide, zirconium oxide, barium sulfate, silicic anhydride, mica, nylon powder, silk powder, and the like. is there.

Examples of the ultraviolet absorber include ethyl paraaminobenzoate, ethylhexyl paradimethylaminobenzoate, amyl salicylate and derivatives thereof, 2-ethylhexyl paramethoxycinnamate, octyl cinnamate, oxybenzone, 2,4-dihydroxybenzophenone, and 2-ethylhexyl cinnamate.
Hydroxy-4-methoxybenzophenone-5-sulfonate, 4-tert-butyl-4-methoxybenzoylmethane, 2- (2-hydroxy-5-methylphenyl) benzotriazole, urocanic acid, ethyl urocanate and the like.

Examples of the antioxidant include butylhydroxyanisole, butylhydroxytoluene, propyl gallate, vitamin E and derivatives thereof.

Examples of the physiologically active components include, as whitening components, kojic acid and its derivatives, ascorbic acid and its derivatives, arbutin and its derivatives, ellagic acid and its derivatives, resorcinol derivatives, soybean extract,
Saxifrage extract, rice bran extract, 2,5-dihydroxybenzoic acid derivative, etc. are used as components for preventing skin aging and improving skin roughness (beautifying skin), collagen, nicotinic acid and its derivatives, vitamin E and its derivatives, α-hydroxy acids ,
Examples include crude drug extracts such as diisopropylamine dichloroacetate, γ-amino-β-hydroxybutyric acid, and gentian extract.

Examples of the kojic acid derivative include kojic acid esters such as kojic acid monobutyrate, kojic acid monocaprate, kojic acid monopalmitate and kojic acid dibutyrate, and kojic acid ethers. Are, for example, sodium L-ascorbic acid-2-phosphate, magnesium L-ascorbic acid-2-phosphate, sodium L-ascorbic acid-2-sulfate, magnesium L-ascorbic acid-2-sulfate, and the like. Ascorbic acid ester salts, L-ascorbic acid-2-glucoside (2-O-α-D-glucopyranosyl-L-ascorbic acid), L-ascorbic acid-5-glucoside (5-O
-Α-D-glucopyranosyl-L-ascorbic acid) and the like, and as the resorcinol derivative, for example, 4-n-butylresorcinol,
-Isoamyl resorcinol and the like, as 2,5-dihydroxybenzoic acid derivatives, for example, 2,5-diacetoxybenzoic acid, 2-acetoxy-5-hydroxybenzoic acid, 2-hydroxy-5-propionyloxybenzoic acid and the like; Examples of the acid derivative include nicotinamide and benzyl nicotinate, and examples of the vitamin E derivative include vitamin E nicotinate and vitamin E linoleate. Examples of the α-hydroxy acid include lactic acid,
Citric acid and α-hydroxyoctanoic acid.

Next, the present invention will be described more specifically with reference to Production Examples, Examples (formulation examples) and Test Examples, but the invention is not limited thereto. In the following, all parts are parts by weight, and all parts are by weight.

Production Example 1 Washed with water milled rice 10 kg, fructose 2% lactic acid bacteria (L. plantarum, 10 ⁸ cells / ml)
Into a fermentation tank with 40 kg of a liquid dispersed in water,
Lactic acid bacteria fermentation was performed at 37 ° C. for 3 days under a nitrogen atmosphere. After completion of the fermentation, the fermented rice was collected by filtration, washed with water, pulverized by an air current pulverizer, and then adjusted to a moisture content of 13% or less with a fluidized bed drier to obtain a lactic acid bacteria fermented rice powder.

Production Example 2 A lactic acid bacteria fermented rice powder was obtained in the same manner as in Production Example 1 except that low-allergen rice (trade name: Fine Rice) was used instead of milled rice.

Production Example 3 Except for using L. casei as a lactic acid bacterium instead of L. plantarum, in the same manner as in Production Example 1,
Similarly, lactic acid bacteria fermented rice powder was obtained.

Production Example 4 A lactic acid bacteria fermented rice powder was obtained in the same manner as in Production Example 1 except that glucose instead of fructose was used as the sugar.

Production Example 5 Washed with water milled rice 10 kg, fructose 2% lactic acid bacteria (L. plantarum, 10 ⁸ cells / ml)
Into a fermentation tank with 40 kg of a liquid dispersed in water,
Lactic acid bacteria fermentation was performed at 37 ° C. for 3 days under a nitrogen atmosphere. After completion of the fermentation, the fermented rice was collected by filtration and washed with water, and 8 kg of the fermented rice was redispersed in 30 kg of water, and ground with a grinder until almost uniform to obtain a lactic acid bacteria fermented rice dispersion.

Production Example 6 2 kg of lactic acid bacteria fermented rice powder and 0.5 kg of hyaluronic acid obtained in Production Example 1 were kneaded with 0.5 kg of 1,3-butylene glycol to obtain a white wet powder.

Production Example 7 2 kg of lactic acid bacteria-fermented rice powder and 0.5 kg of xanthan gum obtained in Production Example 1 were kneaded with 0.5 kg of 1,3-butylene glycol to obtain a white wet powder.

Production Example 8 2 kg of lactic acid bacteria-fermented rice powder and 0.5 kg of xanthan gum obtained in Production Example 1 were kneaded with 2.5 kg of 1,3-butylene glycol to obtain a white paste.

Production Example 9 10 kg of polished rice is washed with water, fructose 2.0%, salt 4.0% and lactic acid bacteria (L. planta
rum, 10 ⁸ cells / ml) were placed in a fermentation tank together with the liquid 40Kg dispersed in water and subjected to 3 days lactic acid fermentation at 37 ° C. under a nitrogen atmosphere. After completion of the fermentation, the fermented rice was collected by filtration, washed with water, pulverized with an air current pulverizer, and adjusted to a moisture content of 13% or less with a fluidized bed drier to obtain a lactic acid bacteria fermented rice powder containing salt.

Embodiment 1 Cream [Component A] Part Liquid paraffin 5.0 Olive oil 4.0 Paraffin 5.0 Cetanol 2.0 Butylparaben 0.1 [Component B] Lactic acid bacteria fermented rice powder of Production Example 1 5.0 1,3-butylene glycol 10 0.0 Methylparaben 0.1 Purified water Amount that makes the total amount 100 parts [Component C] Fragrance 0.3 After the components A and B are each heated to 80 ° C. or higher, the component B is added to the component A and stirred. Hiscotron (50
(00 rpm) for 2 minutes. This is 50
After cooling to C, component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous cream.

Embodiment 2 Emulsion [Component A] part Liquid paraffin 5.0 Olive oil 4.0 Squalane 5.0 Butylparaben 0.1 [Component B] Lactic acid bacterium fermented rice powder of Production Example 1 5.0 1,3-butylene glycol 10.0 Methylparaben 0 .1 Amount of purified water so that the total amount becomes 100 parts [Component C] Fragrance 0.3 After the components A and B are each heated to 80 ° C. or higher, the component B is added to the component A, and the mixture is stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 3 Lotion [A component] part Olive oil 1.0 butyl paraben 0.1 [B component] Lactic acid bacteria fermented rice powder of Production Example 1 1.0 ethanol 5.0 glycerin 5.0 1,3-butylene glycol 5.0 methyl methyl paraben 0 .1 Amount of purified water so that the total amount becomes 100 parts [Component C] Fragrance 0.3 After the components A and B are each heated to 80 ° C. or higher, the component B is added to the component A, and the mixture is stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to 0 ° C., the C component was added and mixed with stirring, and further cooled to 30 ° C. or lower to obtain a milky lotion.

Embodiment 4 Essence [A component] part Olive oil 1.0 butyl paraben 0.1 [B component] Lactic acid bacterium fermented rice powder of Production Example 1 2.0 ethanol 5.0 hyaluronic acid 0.3 1,3-butylene glycol 5.0 methyl methyl paraben 0 .1 Amount of purified water so that the total amount becomes 100 parts [Component C] Fragrance 0.3 After the components A and B are each heated to 80 ° C. or higher, the component B is added to the component A, and the mixture is stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to ℃, the component C was added, mixed with stirring, and further cooled to 30 ℃ or lower to obtain a milky white essence.

Embodiment 5 FIG. 4. Emulsion In the B component of Example 2, lactic acid bacteria fermented rice powder of Production Example 1
A homogeneous emulsion was obtained in the same manner as in Example 2, except that 5.0 parts of the lactic acid bacteria-fermented rice powder of Production Example 2 was used instead of 0 parts.

Embodiment 6 FIG. 4. Emulsion In the B component of Example 2, lactic acid bacteria fermented rice powder of Production Example 1
A homogeneous emulsion was obtained in the same manner as in Example 2, except that 5.0 parts of the lactic acid bacteria-fermented rice powder of Production Example 3 was used instead of 0 parts.

Embodiment 7 FIG. 4. Emulsion In the B component of Example 2, lactic acid bacteria fermented rice powder of Production Example 1
A homogeneous emulsion was obtained in the same manner as in Example 2 except that 5.0 parts of the lactic acid bacteria-fermented rice powder of Production Example 4 was used instead of 0 parts.

Embodiment 8 FIG. 4. Emulsion In the B component of Example 2, lactic acid bacteria fermented rice powder of Production Example 1
A homogeneous emulsion was obtained in the same manner as in Example 2 except that 15.0 parts of the lactic acid bacteria-fermented rice dispersion of Production Example 5 was used instead of 0 parts.

Embodiment 9 FIG. 4. Emulsion In the B component of Example 2, lactic acid bacteria fermented rice powder of Production Example 1
A homogeneous emulsion was obtained in the same manner as in Example 2 except that 2.0 parts of the lactic acid bacteria-fermented rice powder of Production Example 1 and 0.5 part of xanthan gum were used instead of 0 parts.

Embodiment 10 FIG. 4. Emulsion In the B component of Example 2, lactic acid bacteria fermented rice powder of Production Example 1
A homogeneous emulsion was obtained in the same manner as in Example 2 except that 2.5 parts of the paste of Production Example 8 was used instead of 0 part.

Embodiment 11 FIG. Hair treatment [A component] part Stearyltrimethylammonium chloride 5.0 Glyceryl monostearate 1.0 Cetanol 3.0 Octyldodecanol 2.0 [B component] Lactic acid bacterium fermented rice powder of Production Example 1 5.0 1,3- Butylene glycol 5.0 Hydrolyzed collagen powder 0.5 Methyl paraben 0.1 Purified water Amount that total amount becomes 100 parts [C component] Fragrance 0.3 A component and B component are heated to 80 ° C. or higher, respectively, and then A component B component is added to the mixture and stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to ℃, the component C was added, mixed with stirring, and further cooled to 30 ℃ or less.

Embodiment 12 FIG. Hair cream [A component] part Squalane 15.0 Vaseline 15.0 Beeswax 2.0 Methyl paraben Appropriate amount [B component] Glycerin 3.0 1,3-butylene glycol 3.0 Xanthan gum 0.1 Lactic acid bacteria fermented rice of Production Example 1 Powder 5.0 Polyoxyethylene hydrogenated castor oil 3.0 Amount of purified water to make the total amount 100 parts [Component C] Fragrance appropriate amount After heating and dissolving A component and B component respectively at 80 ° C, combine both components. Homogenization was performed with a Hiscotron (5000 rpm) for 2 minutes. This is cooled while stirring, and 50 ° C
Then, the component C was added, and the mixture was further cooled to 30 ° C.

Embodiment 13 FIG. Hair dye / Dye base [Component A] Part Oxidation dye 3.5 Oleic acid 20.0 Stearic acid diethanolamide 3.0 Polyoxyethylene (50) oleyl ether 1.0 [Component B] Lactic acid bacteria fermented rice of Production Example 1 Powder 3.0 1,3-butylene glycol 10.0 Isopropanol 10.0 Aqueous ammonia (28%) 10.0 Sodium sulfite 0.5 Purified water Amount of which total amount is 100 parts A component and B component are each 80 ° C or more. After heating, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This was cooled to 30 ° C. or lower while stirring.

Embodiment 14 FIG. Liquid foundation [Component A] part 2.5 stanolic acid 2.5 cetanol 0.5 glyceryl monostearate 2.0 lanolin 2.0 squalane 3.0 isopropyl myristate 8.0 propylparaben 0.1 [component B] Production Example 1 Lactic acid bacterium fermented rice powder 3.0 Xanthan gum 0.3 1,3-butylene glycol 5.0 Triethanolamine 1.0 Methyl paraben 0.1 Purified water Amount that makes the total amount 100 parts [Component C] Titanium oxide 8.0 Talc 4 0.0 Color pigment suitable amount [D component] Fragrance 0.3 C component was mixed and pulverized with a pulverizer. Mix the B component,
The pulverized C component was added thereto and uniformly dispersed by a colloid mill. After heating the component A and the components B and C uniformly dispersed to 80 ° C., the component A was added to the components B and C while stirring, and homogenized with a Hiscotron (5000 rpm) for 2 minutes. After cooling this to 50 ° C,
Add component D, stir and mix.
Cooled down to:

Embodiment 15 FIG. Cream foundation [Component A] part Stearic acid 5.0 Cetanol 2.0 Glyceryl monostearate 3.0 Liquid paraffin 5.0 Squalane 3.0 Isopropyl myristate 8.0 Propylparaben 0.1 [Component B] Production Example 1 Lactic acid bacterium fermented rice powder 3.0 Sorbitol 3.0 1,3-butylene glycol 5.0 Triethanolamine 1.5 Methyl paraben 0.1 Purified water Amount that the total amount becomes 100 parts [Component C] Titanium oxide 8.0 Talc 2.0 Kaolin 5.0 Bentonite 1.0 Color pigment Appropriate amount [D component] Fragrance 0.3 C component was mixed and pulverized with a pulverizer. Mix the B component,
The pulverized C component was added thereto and uniformly dispersed by a colloid mill. After heating the component A and the components B and C uniformly dispersed to 80 ° C., the component A was added to the components B and C while stirring, and homogenized with a Hiscotron (5000 rpm) for 2 minutes. After cooling this to 50 ° C,
Add component D, stir and mix.
Cooled down to:

Embodiment 16 FIG. Cream rinse [A component] part Polyoxyethylene (10) hydrogenated castor oil 1.0 Distearyldimethylammonium chloride 1.5 Stearyltrimethylammonium chloride 2.0 Glyceryl 2-ethylhexanoate 1.0 Cetanol 3.2 Stearyl alcohol 1 0.0 Methylparaben 0.1 [Component B] Lactic acid bacterium-fermented rice powder of Production Example 1 15.0 1,3-butylene glycol 5.0 Purified water Amount so that the total amount becomes 100 parts A component and B component are each added to 80 ° C. After warming and dissolving uniformly, component B was added to component A, and the mixture was stirred and cooled to room temperature.

Embodiment 17 FIG. Cream shampoo [A component] part Sodium methyltaurine N-coconut oil fatty acid 10.0 Sodium polyoxyethylene (3) alkyl ether sulfate 20.0 Betaine lauryl dimethylaminoacetate 10.0 Diethanolamide coconut oil fatty acid 4.0 Methylparaben 0. 1 [B component] Citric acid 0.1 Lactic acid bacterium fermented rice powder of Example 1 15.0 1,3-butylene glycol 2.0 Purified water Amount that the total amount becomes 100 parts A component and B component are each added to 80 ° C. After warming and dissolving uniformly, component B was added to component A, and the mixture was stirred and cooled to room temperature.

Embodiment 18 FIG. Body shampoo [A component] part sodium N-lauroylmethylalanine 25.0 coconut oil fatty acid potassium solution (40%) 26.0 coconut oil fatty acid diethanolamide 3.0 methyl paraben 0.1 [component B] Lactic acid bacteria fermentation of Production Example 1 Rice powder 10.0 1,3-butylene glycol 2.0 Purified water Amount to make the total amount 100 parts A component and B component are each heated to 80 ° C and uniformly dissolved, and then B component is added to A component Then, stirring was continued, and the mixture was cooled to room temperature.

Embodiment 19 FIG. Antiperspirant (pressed powder) [A component] part Chlorhydroxyaluminum 5.0 Zinc oxide 5.0 Lactic acid bacteria fermented rice powder of Production Example 1 10.0 Amount of talc to be 100 parts [B component] Squalane 3.0 Perfume Appropriate amount Methylparaben Appropriate amount After sufficiently mixing the component A, a solution obtained by dissolving the component B therein was uniformly sprayed and mixed. The obtained powder was pulverized and then compression-molded.

Embodiment 20 FIG. Toothpaste [A component] part Dibasic calcium phosphate dihydrate 60.0 Silicic anhydride 2.0 Flavoring amount [B component] Glycerin 10.0 1,3-butylene glycol 5.0 Lactic acid bacteria fermented rice of Production Example 1 Powder 5.0 Sodium lauryl sulfate 2.0 Carrageenan 0.3 Methyl paraben Appropriate amount Saccharin sodium 0.1 Purified water Amount to make the total amount 100 parts The B component was mixed, heated to 80 ° C, melted and cooled to 30 ° C. After the component A was added and kneaded sufficiently, the mixture was defoamed under reduced pressure.

Embodiment 21 FIG. Emulsion [A component] part liquid paraffin 5.0 olive oil 4.0 squalane 5.0 polyoxyethylene (20) glyceryl monostearate 1.0 glyceryl monostearate 1.0 butyl paraben 0.1 [component B] Production example Lactic acid bacterium fermented rice powder 9 3.0 1,3-butylene glycol 10.0 Methyl paraben 0.1 Purified water Amount of 100 parts in total [C component] Fragrance 0.3 A component and B component each at 80 ° C or higher After heating, add the B component to the A component, stir, and further add Hiscotron (50
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 22 FIG. Cream [A component] part liquid paraffin 5.0 olive oil 4.0 paraffin 5.0 cetanol 2.0 polyoxyethylene (20) sorbitan monostearate 2.0 sorbitan monostearate 2.0 butyl paraben 0.1 [B Ingredient] Lactic acid bacteria fermented rice powder of Production Example 1 5.0 1,3-butylene glycol 10.0 Methyl paraben 0.1 Purified water Amount that the total amount becomes 100 parts [C component] Fragrance 0.3 A component and B component respectively After heating to 80 ° C. or higher, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous cream.

Embodiment 23 FIG. Emulsion [Component A] part liquid paraffin 5.0 olive oil 4.0 squalane 5.0 polyoxyethylene (20) glyceryl monostearate 0.7 glyceryl monostearate 1.0 butyl paraben 0.1 [component B] Production Example 1 Lactic acid bacterium fermented rice powder 3.0 Xanthan gum 0.2 1,3-butylene glycol 10.0 Methyl paraben 0.1 Purified water Amount that the total amount becomes 100 parts [C component] Fragrance 0.3 A component and B component After heating to 80 ° C. or higher, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 24 FIG. Lotion [A component] part Olive oil 1.0 Polyoxyethylene (5.5) cetyl ether 0.5 butyl paraben 0.1 [B component] Lactic acid bacteria fermented rice powder of Production Example 1 1.0 Ethanol 5.0 Glycerin 5 0.0 1,3-butylene glycol 5.0 Methyl paraben 0.1 Purified water Amount that the total amount becomes 100 parts [C component] Fragrance 0.3 After heating each of the A component and the B component to 80 ° C or more, the A component is added. Add component B, stir and add Hiscotron (50
(00 rpm) for 2 minutes. This is 50
After cooling to 0 ° C., the C component was added and mixed with stirring, and further cooled to 30 ° C. or lower to obtain a milky lotion.

Embodiment 25 FIG. Essence [A component] part Olive oil 1.0 Polyoxyethylene (5.5) cetyl ether 0.5 butyl paraben 0.1 [B component] Lactic acid bacteria fermented rice powder of Production Example 1 2.0 Ethanol 5.0 Hyaluronic acid 0 3.3 1,3-butylene glycol 5.0 methyl paraben 0.1 Amount of purified water to make the total amount 100 parts [C component] Fragrance 0.3 After heating each of the A component and the B component to 80 ° C or more, the A component was added. Add component B, stir and add Hiscotron (50
(00 rpm) for 2 minutes. This is 50
After cooling to ℃, the component C was added, mixed with stirring, and further cooled to 30 ℃ or lower to obtain a milky white essence.

Embodiment 26 FIG. Pack (peel-off) [A component] part Polyvinyl alcohol 15.0 Carboxymethylcellulose 2.0 Lactic acid bacterium fermented rice powder of Production Example 5.0 5.0 1,3-butylene glycol 5.0 Purified water Amount that makes the total amount 100 parts [B] Ingredients] Ethanol 15.0 Perfume Appropriate amount Methylparaben Appropriate amount A component was mixed, heated to 85 ° C and dissolved. After cooling the mixture to 50 ° C. or lower, the separately mixed and dissolved B component was added, and the mixture was cooled to 30 ° C. or lower while stirring.

Embodiment 27 FIG. Emulsion In the component B of Example 23, the lactic acid bacteria fermented rice powder 3 of Production Example 1
A milky lotion was obtained in the same manner as in Example 23 except that 3 parts of the lactic acid bacteria-fermented rice powder of Production Example 2 was used instead of the parts.

Embodiment 28 FIG. Emulsion In the component B of Example 23, the lactic acid bacteria fermented rice powder 3 of Production Example 1
An emulsion was obtained in the same manner as in Example 23 except that 3 parts of the lactic acid bacteria-fermented rice powder of Production Example 3 was used instead of the parts.

Embodiment 29 FIG. Emulsion In the component B of Example 23, the lactic acid bacteria fermented rice powder 3 of Production Example 1
An emulsion was obtained in the same manner as in Example 23 except that 3 parts of the lactic acid bacteria-fermented rice powder of Production Example 4 was used instead of the parts.

Embodiment 30 FIG. Emulsion [A component] part liquid paraffin 5.0 olive oil 4.0 squalane 5.0 polyoxyethylene (20) glyceryl monostearate 1.0 glyceryl monostearate 1.0 butyl paraben 0.1 [component B] Production example Lactic acid bacterium fermented rice dispersion liquid 5 15.0 1,3-butylene glycol 10.0 Methyl paraben 0.1 Purified water Amount that the total amount becomes 100 parts [C component] Fragrance 0.3 A component and B component are each 80 ° C or more. After heating, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 31 FIG. Emulsion [A component] part liquid paraffin 5.0 olive oil 4.0 squalane 5.0 polyoxyethylene (20) glyceryl monostearate 1.0 glyceryl monostearate 1.0 butyl paraben 0.1 [component B] Production example 1 Lactic acid bacterium fermented rice powder 3.0 1,3-butylene glycol 10.0 Kojic acid 2.0 Methyl paraben 0.1 Purified water Amount that the total amount becomes 100 parts [C component] Fragrance 0.3 A component and B component After each was heated to 80 ° C. or higher, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 32 FIG. Emulsion In the component B of Example 31, L-
An emulsion was obtained in the same manner as in Example 31, except that 2.0 parts of ascorbic acid-2-glucoside was used.

Embodiment 33 FIG. Emulsion In the component B of Example 31, L-
Magnesium ascorbic acid-2-phosphate ester3.
An emulsion was obtained in the same manner as in Example 31 except that 0 part was used.

Embodiment 34 FIG. Emulsion An emulsion was obtained in the same manner as in Example 31, except that 2.0 parts of arbutin was used in place of 2.0 parts of kojic acid in the component B of Example 31.

Embodiment 35 FIG. Emulsion [Component A] part liquid paraffin 5.0 olive oil 4.0 squalane 5.0 polyoxyethylene (20) glyceryl monostearate 1.0 glyceryl monostearate 1.0 diisopropylamine dichloroacetate 0.5 butylparaben 1 [B component] Lactic acid bacterium fermented rice powder of Production Example 1 3.0 1,3-butylene glycol 10.0 Purified water Amount that total amount becomes 100 parts [C component] Fragrance 0.3 A component and B component are each 80. After heating to at least ℃, the B component was added to the A component, followed by stirring.
(00 rpm) for 2 minutes. This is 50
After cooling to ℃, the component C was added and mixed with stirring, and further cooled to 30 ℃ or less to obtain an emulsion.

Embodiment 36 FIG. Emulsion [Component A] part Liquid paraffin 5.0 Olive oil 4.0 Squalane 5.0 Polyoxyethylene (20) glyceryl monostearate 1.0 Glyceryl monostearate 1.0 γ-amino-β-hydroxybutyric acid 0.5 Butylparaben 0.1 [Component B] Lactic acid bacterium fermented rice powder of Production Example 1 3.0 1,3-butylene glycol 10.0 Purified water Amount of 100 parts in total [Component C] Fragrance 0.3 A component and B After each component was heated to 80 ° C. or higher, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 37 FIG. Emulsion [Component A] part liquid paraffin 5.0 olive oil 4.0 squalane 5.0 polyoxyethylene (20) glyceryl monostearate 1.0 glyceryl monostearate 1.0 diisopropylamine dichloroacetate 0.5 butylparaben 1 [B component] Lactic acid bacterium fermented rice powder of Production Example 1 3.0 1,3-butylene glycol 10.0 L-ascorbic acid-2-glucoside 2.0 Purified water Amount that the total amount becomes 100 parts [C component] Fragrance 0.3 After heating the A component and the B component to 80 ° C. or more, the B component was added to the A component, and the mixture was stirred.
(00 rpm) for 2 minutes. This is 50
After cooling to C, the component C was added and mixed with stirring, and further cooled to 30 C or lower to obtain a homogeneous emulsion.

Embodiment 38 FIG. Liquid Foundation [Component A] Part Stearic Acid 2.5 Cetanol 0.5 Polyoxyethylene (20) Glyceryl Monostearate 2.0 Glyceryl Monostearate 2.0 Lanolin 2.0 Squalane 3.0 Isopropyl Myristate 8.0 Propylparaben 0.1 [Component B] Lactic acid bacteria fermented rice powder of Production Example 1 3.0 Xanthan gum 0.3 1,3-butylene glycol 5.0 Triethanolamine 1.0 Methylparaben 0.1 Purified water Amount [C component] Titanium oxide 8.0 Talc 4.0 Color pigment Suitable amount [D component] Fragrance 0.3 C component was mixed and pulverized with a pulverizer. Mix the B component,
The pulverized C component was added thereto and uniformly dispersed by a colloid mill. After heating the component A and the components B and C uniformly dispersed to 80 ° C., the component A was added to the components B and C while stirring, and homogenized with a Hiscotron (5000 rpm) for 2 minutes. After cooling this to 50 ° C,
Add component D, stir and mix.
Cooled down to:

Embodiment 39 FIG. Cream foundation [A component] part Stearic acid 5.0 Cetanol 2.0 Polyoxyethylene (20) glyceryl monostearate 2.0 Glyceryl monostearate 3.0 Liquid paraffin 5.0 Squalane 3.0 Isopropyl myristate 8.0 0 Propylparaben 0.1 [Component B] Lactic acid bacteria fermented rice powder of Production Example 1 3.0 Sorbitol 3.0 1,3-butylene glycol 5.0 Triethanolamine 1.5 Methylparaben 0.1 Purified water 100 parts in total [Component C] Titanium oxide 8.0 Talc 2.0 Kaolin 5.0 Bentonite 1.0 Color pigment Appropriate amount Component D Fragrance 0.3 The C component was mixed and pulverized with a pulverizer. Mix the B component,
The pulverized C component was added thereto and uniformly dispersed by a colloid mill. After heating the component A and the components B and C uniformly dispersed to 80 ° C., the component A was added to the components B and C while stirring, and homogenized with a Hiscotron (5000 rpm) for 2 minutes. After cooling this to 50 ° C,
Add component D, stir and mix.
Cooled down to:

Embodiment 40 FIG. Powder foundation [A component] Sericite 30.0 Titanium oxide 10.0 Lactic acid bacterium fermented rice powder of Production Example 1 20.0 Zinc stearate 1.0 Bengala 1.0 Yellow iron oxide 3.0 Black iron oxide 0.2 Talc Amount of the total amount to be 100 parts [Component B] Squalane 7.0 Octyldodecyl myristate 4.0 Sorbitan monooleate 0.5 Methylparaben Appropriate amount Flavor Appropriate amount After mixing the A component, B was separately heated and dissolved. The components were added and mixed uniformly, and the resulting mixture was pulverized with a pulverizer and then compression-molded.

Embodiment 41 FIG. Bath agent [A component] part Ethanol 5.0 methyl paraben 0.2 Yellow No. 4 0.1 Fragrance 1.5 [B component] 1,3-butylene glycol 5.0 Lactic acid bacteria fermented rice powder of Production Example 1 10.0 Purification Amount of water to be 100 parts [Component C] Disodium hydrogen phosphate suitable amount Dissolve the component B by heating to 85 ° C, cool to room temperature, add a solution obtained by mixing and dissolving the component A, and then add The pH was adjusted to 7 by adding the component C.

Embodiment 42 FIG. Bubble bath [A component] part Sodium lauryl sulfate 5.0 Sodium polyoxyethylene lauryl ether ether 25.0 Lauric acid ethanolamide 5.0 Glycerin 5.0 1,3-butylene glycol 5.0 Lactic acid bacteria fermented rice of Production Example 1 Powder 10.0 Dye Appropriate amount Purified water Amount to make the total amount 100 parts [Component B] Fragrance Appropriate amount After dissolving the component A by heating at 80 ° C, cooling with stirring, and cooling.
The component B was added at 0 ° C, and the mixture was further cooled to 30 ° C or less.

Test Example 1 Emulsification Stability (Part 1) The emulsification stability of an emulsified product obtained by using the lactic acid bacteria fermented rice powder of Production Example 1 and a commercially available hoshin powder (non-glutinous rice flour) as an emulsifier was compared as a comparative example. [Test Method] Six types of emulsions having the component compositions (units: parts) shown in Table 1 were prepared, and their changes over time were observed.

[0086]

[Table 1]

That is, the component 5 was dissolved in the component 4, and any one of the emulsifiers of the component 2 and the component 3 were added thereto, mixed and heated to 80 ° C. This was added to one of the oily components of Component 1 heated to 80 ° C., and 5000 r
After homogenizing under the condition of pm × 2 minutes, the mixture was cooled with water with stirring and cooled to room temperature. Each of the obtained emulsions was placed in a 50 ml screw bottle, and the emulsified state immediately after preparation and the time-dependent change in the emulsified state when stored at room temperature or 40 ° C. for 3 months were visually observed and evaluated according to the following criteria. did. ◎: good ○: very slight separation is observed after one month or more △: slight separation is observed after two weeks to one month ×: complete separation

[Results] The results are shown in Table 2.

[Table 2]

As shown in Table 2, emulsions obtained using the lactic acid bacteria-fermented rice powder of Production Example 1 (Sample Nos. 1, 2, 3, and 4)
And 5) give a long-term stable emulsion for any of the oily components listed in Table 1. On the other hand, when a normal crushed rice product (upper flour) without lactic acid bacteria fermentation is used (sample No. 6), a stable emulsion cannot be obtained.

Test Example 2 Emulsification Stability (Part 2) The effect on the emulsion stability when a thickener was used in combination with lactic acid bacteria-fermented rice was examined. [Test Method] Four types of emulsions having the component compositions (units: parts) shown in Table 3 were prepared, and their changes over time were observed.

[0091]

[Table 3]

That is, the component 5 was dissolved in the component 4, and one of the components 6 was added thereto and mixed. Separately, after heating the mixture of Components 2 and 3 and Component 1 to 80 ° C., respectively, the mixture of Components 2 and 3 was added to Component 1, and Hiscotron (5000 r.
pm) for 2 minutes. To this, a mixture of the above components 4, 5 and 6 was added, and Hiscotron (5000r) was added.
pm), and then water-cooled to room temperature with stirring. Each of the obtained emulsions was placed in a 50 ml screw bottle, and the emulsified state immediately after preparation and the time-dependent change in the emulsified state when stored at room temperature or 40 ° C. for 3 months were visually observed, and the same as in Test Example 1. Was evaluated according to the criteria of

[Results] The results are shown in Table 4.

[Table 4]

From the results in Table 4, it can be seen that when a thickener is used in combination with lactic acid bacteria-fermented rice, the stability of the obtained emulsion is further improved.

Test Example 3 Emulsion Stability (Part 3) The stabilizing effect of the fermented rice with lactic acid bacteria of the present invention on the emulsification system was examined. [Samples] (1) Emulsion of Example 21 (2) Emulsion obtained in the same manner as Example 21 except that purified water was used in place of B powder of lactic acid bacterium fermented rice of Production Example 9 in component B of Example 21 (Comparative example)

[Test Method] Each sample was placed in a 50 ml screw bottle, and the time-dependent changes in the emulsified state immediately after preparation and the emulsified state when stored at room temperature or at 40 ° C. for 3 months were visually observed. The evaluation was performed according to the same criteria as described above.

[Results] The results are shown in Table 5.

[Table 5]

As shown in Table 5, the emulsion containing the fermented rice with lactic acid bacteria of the present invention (Example 21) was excellent in emulsion stability without causing phase separation even when stored for a long period of time. The emulsions of Examples had insufficient stability, and phase separation was observed from the 14th day under the storage conditions of 40 ° C.

Test Example 4 Inhibitory activity of intracellular tyrosinase activity [Test method] Cultured B16 mouse melanoma cells were
1 × 10 ⁴ cells / well were seeded on a well microplate and 10%
Eagle minimum essential medium containing calf serum (FBS) (ME
After pre-culturing for 1 day in M) at 37 ° C. and 5% CO ₂ , the culture was diluted with 10% of the lactic acid bacteria-fermented rice powder of Production Example 1.
% Aqueous solution (sample solution) was replaced with Eagle MEM containing 10% FBS added to a concentration of 5, 10 or 20%, and cultured under the same conditions for 2 days. Then remove the culture,
After adding 5 mM L-dopa or 0.2% MTT to the cell treatment solution to which a surfactant (TritonX-100) was added and performing a tyrosinase reaction at 37 ° C., a microplate reader (Model 1450, Bio Dodah value at a wavelength of 490 nm and 570-630n
The MTT value was measured in m. For comparison,
The same test was performed when 2 mM kojic acid was added instead of the sample solution and when no sample was added (blank).

[Results] The dopa value obtained in the above test is shown in FIG. 1, and the MTT value is shown in FIG. From the results shown in FIGS. 1 and 2, it can be seen that the fermented rice with lactic acid bacteria of the present invention significantly suppresses intracellular tyrosinase activity without a decrease in cell activity.

Test Example 5 Pigmentation inhibition test The in vivo whitening effect of lactic acid bacteria-fermented rice was evaluated by a pigmentation inhibition test using guinea pigs. [Test Method] The hair of a colored guinea pig (male, 8 weeks of age) at the center of the back at 60 mm in the vertical direction and 30 mm in the horizontal direction was shaved, and this part was divided into two right and left parts. A liquid (sample solution) having the lactic acid bacteria fermented rice powder of Production Example 1 dissolved in purified water to a concentration of 5.0% in one of the compartments, and purified water as a control in the other, 5 ml each in the morning and evening, respectively. Each day for 6 days, and 500 mJ / cm ² once daily before application in the morning to the application site.
Was irradiated with UV-B, and the state of pigmentation at the irradiated site was visually observed on the evening of the sixth day, and evaluated according to the following criteria.

[Evaluation Criteria for Pigmentation]-: No pigmentation observed ±: Minor pigmentation observed +: Mild pigmentation observed 2+: Moderate pigmentation observed 3+: Severe pigmentation observed

[Results] The results are shown in Table 6.

[Table 6]

As is clear from the results in Table 6, the lactic acid bacteria-fermented rice of the present invention has an effect of remarkably inhibiting pigmentation on the skin due to exposure to ultraviolet rays.

Test Example 6 Fibroblast activating action [Test method] Human dermis-derived fibroblast NB1RGB (000824)
Was seeded at 1 × 10 ⁴ cells / well in a 96-well microplate containing a minimum essential medium containing 0.5% FCS, and incubated at 37 ° C. for 1 hour.
After pre-culturing for 5 days, a 10% aqueous solution (sample solution) of the lactic acid bacteria-fermented rice powder of Production Example 1 was added to the medium for 5, 10 or 20%.
And cultured at 37 ° C. for a further 6 days. Next, 0.2% MTT was added to the cell treatment solution to which the culture medium was removed and a surfactant (TritonX-100) was added, followed by adding 3%.
After holding at 7 ° C., a microplate reader (Model 1
450, manufactured by Bio-Rad Co., Ltd.) and wavelength 370-630
The MTT value was measured in nm. For comparison, a similar test was performed for the case where 100 mM glucose was added instead of the sample solution and the case where no sample was added (blank).

[Results] The results are shown in FIG. As shown in FIG. 3, the lactic acid bacteria-fermented rice of the present invention showed MT against fibroblasts.
It has the effect of enhancing T activity and activating the cells.

Test Example 7 Acute toxicity The lactic acid bacteria fermented rice powder of Production Example 1 was
When administered orally at 000 mg / kg and observed, no deaths or abnormal cases were found.

Test Example 8 Skin irritation (Part 1) A sample prepared by kneading the following components with the Japanese Pharmacopoeia hydrophilic petrolatum to a concentration of 5% was used. (1) Lactic acid bacteria fermented rice powder of Production Example 1 (sample of the present invention) (2) polyoxyethylene (20) sorbitan monooleate (comparative sample a) (3) lipophilic glyceryl monostearate (comparative sample b) ( 4) Glycerin oleate (Comparative sample c) (5) Polyoxyethylene (5) Lauryl ether (Comparative sample d)

[Test Method] Five adult males aged 20 to 50 years were used as subjects, and the inner side of each upper arm was wiped with ethanol to remove sebum, and each sample was placed on an aluminum plate in a fin chamber. .2 g was applied.
Twenty-four hours later, the fin chamber was removed, and the degree of skin irritation was determined by the following method and criteria.

[Judgment] One hour, 24 hours and 48 hours after patch removal, the condition of erythema and edema at the application site was visually judged based on the following “Criteria for skin irritation by Draize method”. The average value of five persons was calculated.

[Results] The results are shown in Table 7.

[Table 7] (Note) Average of 5 people

The activators a to d used as comparative samples in this test are said to be relatively safe, and are widely used for emulsification of cosmetics. As is evident, the lactic acid bacteria-fermented rice powder of the present invention has less skin irritation than those active agents and is extremely excellent in safety.

Test Example 9 Skin irritation (Part 2) A sample prepared by kneading the following components with a hydrophilic vaseline of JP to a concentration of 5% was used as a sample. (1) Hydrophilic petrolatum (JP) (control) (2) Lactic acid bacteria fermented rice powder of Production Example 1 (sample of the present invention) (3) Arbutin (comparative sample a) (4) Kojic acid (comparative sample b)

[Test Method] and [Judgment] The test was carried out in the same manner and in the same manner as in Test Example 8.

[Results] Table 8 shows the results.

[Table 8] (Note) Average of 5 people

The whitening agents of Comparative Samples a and b used for comparison in this test are widely used in whitening cosmetics because of their relatively high safety. The lactic acid bacteria-fermented rice of the present invention has much less skin irritation than these conventional whitening agents and is extremely excellent in safety.

Test Example 10 Monitor Test (Part 1) Emulsion of Example 2 (Using Lactic Acid Bacteria Fermented Rice Alone) and Example 10 Obtained Using the Lactic Acid Bacteria Fermented Rice of the Present Invention as an Emulsifier
Of milk (lactic acid bacteria-fermented rice / thickener combination) was evaluated for use feeling and safety (irritation, etc.) by an actual use test using a monitor.

[Test Method] Age 20 to 4 randomly selected
Using 20 0-year-old women as panelists, using the emulsions of Example 2 and Example 10 separately at different times of use, twice a morning and evening, and applied to the cheeks of the face for 5 days,
The irritation and the like were evaluated for each of the following items. The evaluation was performed on a five-point scale (A: good,
B: Somewhat good, C: Normal, D: Somewhat bad, E: Bad), and the irritancy was evaluated on a three-point scale (A: No stimulus, B: Uncomfortable, C: Stimulated). (Feel of use) Feeling picked up Elongation at the time of application Smoothness at the time of application Permeability (permeation) Feeling after application (skin condition) Skin condition after application (irritant) Stimulation at application After application stimulation

[Results] The results are shown in Tables 9 and 10.

[Table 9]

[0120]

[Table 10]

As shown in Tables 9 and 10, Examples 2 and 1 were prepared using lactic acid bacteria-fermented rice as an emulsifier.
All of the emulsions having a rating of 0 received high evaluation in terms of feeling of use, and no skin irritation was observed.

Test Example 11 Monitor Test (Part 2) The cream rinse of Example 16 containing the lactic acid bacteria-fermented rice of the present invention and the cream rinse obtained by using purified water in place of the lactic acid bacteria-fermented rice powder in Example 16 for comparison. About Comparative Example), the influence on the hair was examined by a half head test. [Test method] 2 women aged 20-40 years randomly selected
0 persons were used as panelists, the cream rinses of Example 16 and Comparative Example were used for hair every day, and 10 days later, the hair was combed, the hair was united and the gloss was evaluated based on the following evaluation criteria. .

(Comb-like) A: remarkably improved B: improved C: unchanged D: slightly deteriorated E: remarkably deteriorated (cohesion of hair) A: remarkably improved B : Improved C: unchanged D: slightly deteriorated E: significantly deteriorated (glossy gloss) A: significantly improved B: improved C: not changed D: slightly deteriorated E: markedly worse

[Results] Table 11 shows the results.

[Table 11]

As is evident from the results in Table 11, the cream rinse containing the fermented lactic acid bacteria rice of the present invention has a comb-like property based on the water retention / moisturizing power, the hair protection effect, etc. of the lactic acid bacteria fermented rice as a component. As well as good hair quality is maintained in a healthy and favorable condition. In addition, the cream rinse of the present invention showed a creamy and soft foaming, and was highly evaluated for the feeling of use.

Test Example 12 Monitor Test (Part 3) For each of the following samples, the inhibitory effect on skin pigmentation and the skin irritation were examined by a monitor test. [Samples] (1) Emulsion of Example 2 (Example of the present invention) (2) Emulsion obtained in Example 31 by using purified water instead of lactic acid bacteria fermented rice powder of Production Example 1 (Comparative Example) 3) Emulsion obtained by using purified water instead of lactic acid bacteria fermented rice powder of Production Example 1 in Example 2 (control example)

[Test Method] Randomly selected ages 18 to
Twenty 50-year-old women were applied as test subjects. Each emulsion was applied to the left upper arm twice a day (morning and evening) for one month, and the pigmentation state of the applied part and erythema of the skin were visually observed. Was evaluated based on the following evaluation criteria.

[Evaluation Criteria] (Pigmentation) A: disappeared B: apparently decreased C: somewhat decreased D: hardly changed E: increased rather (erythema) A: difference from control example No: B: almost no difference from the control example C: erythema is slightly more noticeable than the control example D: considerable erythema is more noticeable than the control example E: erythema is clearly more noticeable than the control example

[Results] The results are shown in Table 12.

[Table 12]

As shown in Table 12, the emulsion containing the fermented lactic acid bacterium of the present invention has an excellent effect of preventing pigmentation and has high safety with little irritation to the skin.

The lactic acid bacteria-fermented rice used as a compounding component in the cosmetic of the present invention has a good emulsifying action and an emulsifying stabilizing action, as well as a water-retaining / moisturizing action, and a protective / adhesive action on the skin and hair. Since it is derived from rice, it has features such as low toxicity and little skin irritation.Accordingly, according to the present invention, it has excellent emulsification stability and biosafety, and has a good feeling upon use and after use. An effective cosmetic for improving the quality and hair quality is provided. In addition, the fermented rice lactic acid bacteria used in the present invention has a strong melanin production inhibitory action and a fibroblast activating action, and the cosmetic of the present invention is effective in preventing skin pigmentation such as spots and freckles and improving symptoms, It is also useful for preventing skin aging and improving skin roughness.

[Brief description of the drawings]

FIG. 1 is a graph showing the dopa value of each sample of Test Example 4 (vertical axis: dopa value).

FIG. 2 is a graph showing the MTT value of each sample of Test Example 4 (vertical axis: MTT value)

FIG. 3 is a graph showing the MTT value of each sample of Test Example 6 (vertical axis: MTT value)

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[Procedure amendment]

[Submission date] July 4, 2002 (2002.7.4)

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[Document name to be amended] Statement

[Correction target item name] Claims

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[Claims]

[Procedure amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0001

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[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic containing a processed rice product and a compounding agent for a cosmetic comprising the processed rice product , and more particularly to a cosmetic such as an emulsifier or an emulsion stabilizer. Not only useful as a base material of but also has excellent cosmetic effects such as whitening / beautifying effect and hair quality improving effect,
Moreover, a cosmetic product containing a processed rice product having high biosafety, and an emulsifier and an emulsifier for the cosmetic product comprising the processed rice product
The present invention relates to a stabilizing agent, a whitening / skin-beautifying agent, and a hair treatment agent .

[Procedure amendment 3]

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[Correction target item name] 0006

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[0006] That is, the present invention is a cosmetic characterized by blending lactic acid bacteria fermented rice obtained by fermenting rice with lactic acid bacteria. The present invention is also obtained by fermenting rice with lactic acid bacteria.
Emulsifier for cosmetics comprising lactic acid bacteria fermented rice, also said lactic acid
An emulsion stabilizer comprising fermented rice, and
Head made of lactic acid bacteria fermented rice
It also relates to a hair treatment agent. The cosmetics according to the present invention include quasi-drugs in addition to so-called cosmetics.

[Procedure amendment 4]

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[Correction target item name] 0010

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The liquid containing lactic acid bacteria-fermented rice obtained by the above fermentation step is subjected to a milling step as it is, and if necessary, concentrated and blended into a cosmetic.
Although it may be used as a compounding agent , more generally, fermented rice from lactic acid bacteria is separated from the fermentation broth, washed with water, adjusted for moisture if necessary, and then pulverized using an appropriate means such as a stream pulverizer. And then, if necessary, dry and mix into cosmetics
Or as a compounding agent for cosmetics.

[Procedure amendment 5]

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[Correction target item name] 0013

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[0013] In addition, the fermented rice for lactic acid bacteria used in the present invention comprises:
It has high water retention / moisturizing power and foam stabilizing effect, as well as protection and adhesion effects on hair, skin, etc.
When used in hair cleansing cosmetics such as shampoos and rinses as a hair treatment agent, foaming is creamy when used and has a good feeling on use, while protecting and improving the hair and protecting and improving the hair. While suppressing the generation of hair and hair breakage, it is possible to obtain a product having excellent properties such as imparting a desirable moist feeling and luster to hair after use.
In addition, as a result of the above-mentioned high water retention / moisturizing power of the lactic acid bacteria-fermented rice, the effect of adhesion to hair, skin, etc., the cosmetic obtained by blending the fermented rice has characteristics not found in conventional base materials. And favorable feeling of use (elongation during application,
(Smoothness etc.) and feeling after use (moist feeling etc.).

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[Correction target item name] 0021

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On the other hand, when lactic acid bacteria-fermented rice is blended into cosmetics as a whitening / skinning agent, the blending amount is generally 0.1% for basic cosmetics, makeup cosmetics and quasi-drugs.
1 to 10% by weight, preferably in the range of 0.5 to 5% by weight,
The amount of the bathing agent is generally in the range of 1 to 30% by weight, preferably 3 to 15% by weight. In addition, lactic acid bacteria fermented rice
When used as a hair treatment agent, the amount may be, for example,
In the case of shampoo, hair rinse, etc., generally
1 to 30% by weight, preferably 5 to 20% by weight
You.

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[Correction target item name] 0033

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Next, a production example (preparation of the compounding agent of the present invention)
Examples), Examples (Presentation examples of the cosmetic of the present invention ) and Test Examples further illustrate the present invention, but the present invention is not limited thereto. In the following, all parts are parts by weight, and all parts are by weight.

[Procedure amendment 8]

[Document name to be amended] Statement

[Correction target item name] 0130

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As shown in Table 12, the emulsion containing the fermented lactic acid bacterium of the present invention has an excellent effect of preventing pigmentation and has high safety with little irritation to the skin.

The lactic acid bacteria-fermented rice of the present invention has a good emulsifying action and an emulsifying and stabilizing action, as well as a water-retaining / moisturizing action, and a protective / adhesive action on the skin and hair, and has a low effect because it is derived from rice. It is toxic and has less skin irritation .
It is useful as an agent or a hair treatment agent. Therefore, this
When lactic acid bacteria-fermented rice is added to a cosmetic, a cosmetic is provided which is excellent in emulsification stability and biosafety, has good feeling upon use and after use, and is effective for improving skin quality and hair quality.
Further, lactic acid bacteria fermentation rice used in the present invention, beauty from Rutokoro comprises a strong melanogenesis inhibitory effect and fibroblast activation action
It is also useful as a whitening / beautifying agent and contains lactic acid bacteria fermented rice.
The resulting cosmetic composition of the present invention exerts excellent effects on prevention of skin pigmentation such as spots and freckles and improvement of symptoms, as well as prevention of skin aging and improvement of rough skin .

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat ゛ (Reference) A61K 7/075 A61K 7/075 7/08 7/08 7/11 7/11 7/13 7/13 7 / 16 7/16 7/48 7/48 7/50 7/50 (72) Inventor Yutaka Osawa 1-6-8 Kitahorie, Nishi-ku, Osaka City Inside Technoble Co., Ltd. (72) Inventor Ayako Hirota Osaka 1-6-8 Kitahorie, Nishi-ku Inside Technoble Co., Ltd. (72) Inventor Takako Ogura 1-6-8 Kitahorie, Nishi-ku, Osaka City F-term inside Technoble Co., Ltd. 4C083 AA082 AA111 AA112 AA122 AA162 AB032 AB172 AB232 AB242 AB292 AB332 AB352 AB442 AC022 AC072 AC092 AC102 AC122 AC132 AC182 AC242 AC422 AC432 AC442 AC482 AC542 AC642 AC662 AC692 AC712 AC782 AC842 AC862 AD112 AD272 AD332 AD352 AD432 AD512 BB04 BB05 BB06 BB07 BB22 BB13 BB22 BB13 BB22 BB13 BB22 B46 BB48 CC04 CC05 CC06 CC07 CC12 CC17 CC23 CC25 CC32 CC33 CC36 CC38 CC39 CC41 DD17 DD23 DD31 DD39 EE10 EE16 EE29

Claims (1)

[Claims] 1. A cosmetic composition comprising lactic acid bacteria-fermented rice obtained by fermenting rice with lactic acid bacteria.