JP2002338494A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002338494A5 JP2002338494A5 JP2001316115A JP2001316115A JP2002338494A5 JP 2002338494 A5 JP2002338494 A5 JP 2002338494A5 JP 2001316115 A JP2001316115 A JP 2001316115A JP 2001316115 A JP2001316115 A JP 2001316115A JP 2002338494 A5 JP2002338494 A5 JP 2002338494A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- composition
- derivatives
- group
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 20
- 239000003814 drug Substances 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 6
- 239000000651 prodrug Substances 0.000 claims 6
- 229940002612 prodrug Drugs 0.000 claims 6
- 229960003515 bendroflumethiazide Drugs 0.000 claims 5
- HDWIHXWEUNVBIY-UHFFFAOYSA-N bendroflumethiazidum Chemical compound C1=C(C(F)(F)F)C(S(=O)(=O)N)=CC(S(N2)(=O)=O)=C1NC2CC1=CC=CC=C1 HDWIHXWEUNVBIY-UHFFFAOYSA-N 0.000 claims 5
- ANMLJLFWUCQGKZ-UHFFFAOYSA-N 2-[3-(trifluoromethyl)anilino]-3-pyridinecarboxylic acid (3-oxo-1H-isobenzofuran-1-yl) ester Chemical compound FC(F)(F)C1=CC=CC(NC=2C(=CC=CN=2)C(=O)OC2C3=CC=CC=C3C(=O)O2)=C1 ANMLJLFWUCQGKZ-UHFFFAOYSA-N 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 229960005262 talniflumate Drugs 0.000 claims 4
- KHMNCHDUSFCTGK-UHFFFAOYSA-N 2-aminophenylacetic acid Chemical class NC1=CC=CC=C1CC(O)=O KHMNCHDUSFCTGK-UHFFFAOYSA-N 0.000 claims 3
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical class NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 claims 3
- 239000003172 expectorant agent Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- UWWWKRZMADICMN-UHFFFAOYSA-N 1-[(3-fluorophenyl)methyl]-2h-quinolin-3-amine Chemical compound C1C(N)=CC2=CC=CC=C2N1CC1=CC=CC(F)=C1 UWWWKRZMADICMN-UHFFFAOYSA-N 0.000 claims 2
- KPIVDNYJNOPGBE-UHFFFAOYSA-N 2-aminonicotinic acid Chemical class NC1=NC=CC=C1C(O)=O KPIVDNYJNOPGBE-UHFFFAOYSA-N 0.000 claims 2
- PJJGZPJJTHBVMX-UHFFFAOYSA-N 5,7-Dihydroxyisoflavone Chemical compound C=1C(O)=CC(O)=C(C2=O)C=1OC=C2C1=CC=CC=C1 PJJGZPJJTHBVMX-UHFFFAOYSA-N 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 2
- JZFPYUNJRRFVQU-UHFFFAOYSA-N Niflumic acid Chemical compound OC(=O)C1=CC=CN=C1NC1=CC=CC(C(F)(F)F)=C1 JZFPYUNJRRFVQU-UHFFFAOYSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 230000004663 cell proliferation Effects 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 230000003419 expectorant effect Effects 0.000 claims 2
- LPEPZBJOKDYZAD-UHFFFAOYSA-N flufenamic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1 LPEPZBJOKDYZAD-UHFFFAOYSA-N 0.000 claims 2
- 229960004369 flufenamic acid Drugs 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 229960003464 mefenamic acid Drugs 0.000 claims 2
- 239000011859 microparticle Substances 0.000 claims 2
- 229960000916 niflumic acid Drugs 0.000 claims 2
- 208000023504 respiratory system disease Diseases 0.000 claims 2
- 230000004044 response Effects 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 206010066091 Bronchial Hyperreactivity Diseases 0.000 claims 1
- 206010006458 Bronchitis chronic Diseases 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 206010009137 Chronic sinusitis Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- 206010014561 Emphysema Diseases 0.000 claims 1
- 208000018522 Gastrointestinal disease Diseases 0.000 claims 1
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical group COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 206010025476 Malabsorption Diseases 0.000 claims 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 claims 1
- 208000037581 Persistent Infection Diseases 0.000 claims 1
- 102000000033 Purinergic Receptors Human genes 0.000 claims 1
- 108010080192 Purinergic Receptors Proteins 0.000 claims 1
- 206010041660 Splenomegaly Diseases 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- -1 antibiotic Substances 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 claims 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 206010006451 bronchitis Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000023819 chronic asthma Diseases 0.000 claims 1
- 208000007451 chronic bronchitis Diseases 0.000 claims 1
- 208000027157 chronic rhinosinusitis Diseases 0.000 claims 1
- 239000000850 decongestant Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000003979 eosinophil Anatomy 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 230000000762 glandular Effects 0.000 claims 1
- 210000002175 goblet cell Anatomy 0.000 claims 1
- 229960002146 guaifenesin Drugs 0.000 claims 1
- 230000036732 histological change Effects 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 229940071648 metered dose inhaler Drugs 0.000 claims 1
- 229940066491 mucolytics Drugs 0.000 claims 1
- 229960002715 nicotine Drugs 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000003973 paint Substances 0.000 claims 1
- 239000002304 perfume Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000018 receptor agonist Substances 0.000 claims 1
- 229940044601 receptor agonist Drugs 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 208000001162 steatorrhea Diseases 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24213400P | 2000-10-23 | 2000-10-23 | |
| US60/242,134 | 2000-10-23 | ||
| US25205200P | 2000-11-20 | 2000-11-20 | |
| US60/252,052 | 2000-11-20 | ||
| US09/918,711 | 2000-11-20 | ||
| US09/774,243 | 2000-11-20 | ||
| US09/774,243 US6737427B2 (en) | 2000-01-31 | 2001-01-31 | Mucin synthesis inhibitors |
| US91871101A | 2001-08-01 | 2001-08-01 | |
| US09/920,287 US20020165244A1 (en) | 2000-01-31 | 2001-08-02 | Mucin synthesis inhibitors |
| US09/920,287 | 2001-08-02 | ||
| US09/951,906 US20020147216A1 (en) | 2000-01-31 | 2001-09-14 | Mucin synthesis inhibitors |
| US09/951,906 | 2001-09-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002338494A JP2002338494A (ja) | 2002-11-27 |
| JP2002338494A5 true JP2002338494A5 (https=) | 2005-06-30 |
Family
ID=27559313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001316115A Pending JP2002338494A (ja) | 2000-10-23 | 2001-10-12 | ムチン合成インヒビター |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002338494A (https=) |
-
2001
- 2001-10-12 JP JP2001316115A patent/JP2002338494A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004507444A5 (https=) | ||
| US7238661B2 (en) | Oral lactoferrin in the treatment of respiratory disorders | |
| JP6021117B2 (ja) | エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用 | |
| US11090294B2 (en) | Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist | |
| TWI229601B (en) | Combinations of a beta-2 agonist and a steroid | |
| CN102946868B (zh) | 包含抗毒蕈碱药的干粉制剂 | |
| ES2699507T3 (es) | Composición farmacéutica que comprende una suspensión acuosa de un derivado de androstano para el tratamiento de afecciones inflamatorias y alérgicas | |
| JP6594853B2 (ja) | チオ糖粘液溶解薬 | |
| JP2002536408A (ja) | フォルモテロールとチオトロピウム塩の組合わせ | |
| JP2010518122A5 (https=) | ||
| JP2014525471A (ja) | 咳および咳発作の治療 | |
| WO2004043392B1 (en) | Mucin synthesis inhibitors | |
| US20240307333A1 (en) | Anti-viral therapeutic agents and uses thereof | |
| RU2003131178A (ru) | Агонисты никотиновых рецепторов для лечения воспалительных заболеваний | |
| CN106470700A (zh) | 用于治疗copd的噻托溴铵、福莫特罗和布地奈德的组合 | |
| JP2004532900A5 (https=) | ||
| JP2008516991A5 (https=) | ||
| RU2007107935A (ru) | Полисульфатированные гликозиды и их соли | |
| JP2023524693A (ja) | ラクトフェリンの投与によるＳＡＲＳ－ＣｏＶ－２ウイルス侵入の阻害およびその使用 | |
| CA2827299A1 (en) | Liquid propellant-free formulation comprising an antimuscarinic drug | |
| PT1594500E (pt) | Tratamento para doenças bacterianas dos órgãos respiratórios por aplicação local de fluoroquinolonas | |
| JP2002338494A5 (https=) | ||
| JP2013518061A5 (https=) | ||
| HRP20241621T1 (hr) | (1r,3s)-3-((5-cijano-4-feniltiazol-2-il)karbamoil)ciklopentan-1-karboksilna kiselina, namijenjena upotrebi u liječenju bolesti dišnih puteva | |
| Malamatari | Inhaled theophylline: old drug new tricks? |