JP2001527382A5 - - Google Patents

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Publication number
JP2001527382A5
JP2001527382A5 JP1997525811A JP52581197A JP2001527382A5 JP 2001527382 A5 JP2001527382 A5 JP 2001527382A5 JP 1997525811 A JP1997525811 A JP 1997525811A JP 52581197 A JP52581197 A JP 52581197A JP 2001527382 A5 JP2001527382 A5 JP 2001527382A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1997525811A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001527382A (ja
Filing date
Publication date
Priority claimed from GBGB9601096.2A external-priority patent/GB9601096D0/en
Priority claimed from GBGB9615845.6A external-priority patent/GB9615845D0/en
Application filed filed Critical
Priority claimed from PCT/GB1997/000153 external-priority patent/WO1997026356A1/en
Publication of JP2001527382A publication Critical patent/JP2001527382A/ja
Publication of JP2001527382A5 publication Critical patent/JP2001527382A5/ja
Ceased legal-status Critical Current

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JP52581197A 1996-01-19 1997-01-17 スタフィロコッカス・アウレウス由来のフェニルアラニル−tRNAシンセターゼ Ceased JP2001527382A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9601096.2A GB9601096D0 (en) 1996-01-19 1996-01-19 Novel compounds
GB9601096.2 1996-07-27
GBGB9615845.6A GB9615845D0 (en) 1996-07-27 1996-07-27 Novel compounds
GB9615845.6 1996-07-27
PCT/GB1997/000153 WO1997026356A1 (en) 1996-01-19 1997-01-17 PHENYLALANYL-tRNA SYNTHETASE FROM STAPHYLOCOCCUS AUREUS

Publications (2)

Publication Number Publication Date
JP2001527382A JP2001527382A (ja) 2001-12-25
JP2001527382A5 true JP2001527382A5 (https=) 2004-11-04

Family

ID=26308495

Family Applications (2)

Application Number Title Priority Date Filing Date
JP9525809A Pending JPH11504524A (ja) 1996-01-19 1997-01-17 スタフィロコッカス・アウレウスのヒスチジル−tRNAシンセターゼ
JP52581197A Ceased JP2001527382A (ja) 1996-01-19 1997-01-17 スタフィロコッカス・アウレウス由来のフェニルアラニル−tRNAシンセターゼ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP9525809A Pending JPH11504524A (ja) 1996-01-19 1997-01-17 スタフィロコッカス・アウレウスのヒスチジル−tRNAシンセターゼ

Country Status (4)

Country Link
US (2) US5756329A (https=)
EP (4) EP0785262A1 (https=)
JP (2) JPH11504524A (https=)
WO (2) WO1997026356A1 (https=)

Families Citing this family (38)

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US5756329A (en) * 1996-01-19 1998-05-26 Smithkline Beecham P.L.C. DNA encoding phenylalanyl tRNA synthetase from Staphylococcus aureus
EP0916728A1 (en) * 1997-10-17 1999-05-19 Smithkline Beecham Corporation Phenyl alanyl tRNA synthetase [EC 6.1.1.20] alpha subunit family, pheS (alpha), from Streptococcus pneumoniae
CN102105164A (zh) 2008-06-11 2011-06-22 Atyr医药公司 酪氨酰-trna合成酶多肽的血小板生成活性
US8404471B2 (en) 2008-06-26 2013-03-26 Atyr Pharma, Inc. Compositions and methods comprising glycyl-tRNA synthetases having non-canonical biological activities
WO2010099477A2 (en) 2009-02-27 2010-09-02 Atyr Pharma, Inc. Polypeptide structural motifs associated with cell signaling activity
EP2408905B1 (en) 2009-03-16 2017-05-10 Pangu Biopharma Limited Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities
CN102449143B (zh) 2009-03-31 2017-11-14 Atyr医药公司 包含具有非常规生物活性的天冬氨酰‑tRNA合成酶的组合物和方法
US8828395B2 (en) 2009-12-11 2014-09-09 Atyr Pharma, Inc. Antibodies that bind tyrosyl-tRNA synthetases
CN106474462A (zh) * 2009-12-11 2017-03-08 Atyr 医药公司 用于调节炎症的氨酰tRNA合成酶
US8980253B2 (en) 2010-04-26 2015-03-17 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
CA2797362C (en) 2010-04-27 2020-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases
EP2563382B1 (en) 2010-04-27 2017-06-07 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl trna synthetases
WO2011139853A2 (en) 2010-04-28 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
CA2797393C (en) 2010-04-29 2020-03-10 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
CA2797374C (en) 2010-04-29 2021-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases
CA2797799C (en) 2010-05-03 2020-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases
US8961961B2 (en) 2010-05-03 2015-02-24 a Tyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases
CN103140233B (zh) 2010-05-03 2017-04-05 Atyr 医药公司 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
CN103096912A (zh) 2010-05-03 2013-05-08 Atyr医药公司 与苯丙氨酰-α-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
JP6008844B2 (ja) 2010-05-04 2016-10-19 エータイアー ファーマ, インコーポレイテッド p38MULTI−tRNA合成酵素複合体のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
US9062301B2 (en) 2010-05-04 2015-06-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-tRNA synthetases
EP2568996B1 (en) 2010-05-14 2017-10-04 aTyr Pharma, Inc. Therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
CN103096914B (zh) 2010-05-17 2015-08-12 Atyr医药公司 与亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CA2800375C (en) 2010-05-27 2021-03-09 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases
EP2575857B1 (en) 2010-06-01 2018-01-24 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
US20130202576A1 (en) 2010-07-12 2013-08-08 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
EP2593125B1 (en) 2010-07-12 2017-11-01 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
WO2012009289A2 (en) 2010-07-12 2012-01-19 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases
US8999321B2 (en) 2010-07-12 2015-04-07 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
AU2011293294B2 (en) 2010-08-25 2016-03-24 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Tyrosyl-tRNA synthetases
CA2812795C (en) 2010-10-06 2021-08-31 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases
US9714419B2 (en) 2011-08-09 2017-07-25 Atyr Pharma, Inc. PEGylated tyrosyl-tRNA synthetase polypeptides
US9816084B2 (en) 2011-12-06 2017-11-14 Atyr Pharma, Inc. Aspartyl-tRNA synthetases
US9822353B2 (en) 2011-12-06 2017-11-21 Atyr Pharma, Inc. PEGylated aspartyl-tRNA synthetase polypeptides
WO2013115926A2 (en) 2011-12-29 2013-08-08 Atyr Pharma, Inc. Aspartyl-trna synthetase-fc conjugates
MX356107B (es) 2012-02-16 2018-05-15 Atyr Pharma Inc Histidil-arnt sintetasas para tratar enfermedades autoinmunes e inflamatorias.
CN105378075B (zh) 2013-03-15 2022-04-05 Atyr 医药公司 组氨酰-trna合成酶-fc缀合物
CN110536694A (zh) 2017-04-20 2019-12-03 Atyr 医药公司 用于治疗肺部炎症的组合物和方法

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
AU6958194A (en) * 1993-05-28 1994-12-20 Massachusetts Institute Of Technology Trna binding-dependent inhibition of microbial pathogen growth
GB9320563D0 (en) * 1993-10-06 1993-11-24 Zeneca Ltd Assay procedure and application in identification of herbicides
US5561054A (en) * 1995-05-15 1996-10-01 Board Of Trustees Operating Michigan State University Recombinant asparaginyl-tRNA synthetase from the human filarial parasite, brugia malayi
WO1997005126A1 (en) * 1995-07-29 1997-02-13 Smithkline Beecham Plc Mupirocinsulfamates with antibacterial activity
US6737248B2 (en) * 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US5756329A (en) * 1996-01-19 1998-05-26 Smithkline Beecham P.L.C. DNA encoding phenylalanyl tRNA synthetase from Staphylococcus aureus

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