|
US6887707B2
(en)
*
|
1996-10-28 |
2005-05-03 |
University Of Washington |
Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA
|
|
NZ507848A
(en)
*
|
1996-10-28 |
2005-01-28 |
Univ Washington |
Method of increasing the mutation rate of a virus in a non-human by administering an RNA nucleoside analogue to a virally infected cell
|
|
US6423695B1
(en)
*
|
1998-01-13 |
2002-07-23 |
Ribapharm, Inc. |
Cytokine related treatments of disease
|
|
AU779280B2
(en)
*
|
1999-03-26 |
2005-01-13 |
Walter Reed Army Institute Of Research |
Multivalent dengue virus vaccine
|
|
AU8038400A
(en)
*
|
1999-09-09 |
2001-04-10 |
Zymetx, Inc. |
Method of treatment of influenza
|
|
EP1226238A2
(en)
*
|
1999-10-27 |
2002-07-31 |
Cytos Biotechnology AG |
Method for creating divergent populations of nucleic acid molecules and proteins
|
|
US7638496B2
(en)
|
2000-02-15 |
2009-12-29 |
Valeant Pharmaceuticals North America |
Nucleoside analogs with carboxamidine modified monocyclic base
|
|
SK11922002A3
(sk)
|
2000-02-18 |
2003-06-03 |
Shire Biochem Inc. |
Použitie analógov nukleozidov na liečenie alebo prevenciu infekcií spôsobených flavivírusom
|
|
MY164523A
(en)
*
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
PL359169A1
(en)
*
|
2000-05-26 |
2004-08-23 |
Idenix (Cayman) Limited |
Methods and compositions for treating flaviviruses and pestiviruses
|
|
KR20090089922A
(ko)
*
|
2000-10-18 |
2009-08-24 |
파마셋 인코포레이티드 |
바이러스 감염 및 비정상적인 세포 증식의 치료를 위한 변형된 뉴클레오시드
|
|
MXPA03006514A
(es)
*
|
2001-01-22 |
2004-12-02 |
Merck & Co Inc |
Derivados de nucleosidos como inhibidores de polimerasa de acido ribonucleico viral dependiente de acido ribonucleico.
|
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
WO2002069903A2
(en)
*
|
2001-03-06 |
2002-09-12 |
Biocryst Pharmaceuticals, Inc. |
Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
|
AU2002326736B2
(en)
|
2001-08-24 |
2007-08-02 |
Koronis Pharmaceuticals, Inc. |
Mutagenic nucleoside analogs for the treatment of viral disease
|
|
WO2003026675A1
(en)
*
|
2001-09-28 |
2003-04-03 |
Idenix (Cayman) Limited |
Methods and compositions for treating flaviviruses and pestiviruses using 4'-modified nucleoside
|
|
US7049303B2
(en)
*
|
2001-11-07 |
2006-05-23 |
Medical Research Council |
Inhibition of viruses
|
|
US20040138170A1
(en)
*
|
2002-03-06 |
2004-07-15 |
Montgomery John A. |
Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
CN101172993A
(zh)
*
|
2002-06-28 |
2008-05-07 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2′－c－甲基－3′－o－l－缬氨酸酯核糖呋喃基胞苷
|
|
KR20050035194A
(ko)
*
|
2002-06-28 |
2005-04-15 |
이데닉스 (케이만) 리미티드 |
플라비비리다에 감염 치료용 2'-ｃ-메틸-3'-ｏ-ｌ-발린에스테르 리보푸라노실 사이티딘
|
|
JP4709545B2
(ja)
|
2002-07-26 |
2011-06-22 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
修飾された低分子干渉ｒｎａ分子および使用方法
|
|
AU2003298658A1
(en)
|
2002-11-15 |
2004-06-15 |
Idenix (Cayman) Limited |
2'-branched nucleosides and flaviviridae mutation
|
|
US7598373B2
(en)
*
|
2002-12-12 |
2009-10-06 |
Idenix Pharmaceuticals, Inc. |
Process for the production of 2-C-methyl-D-ribonolactone
|
|
JP2006524227A
(ja)
*
|
2003-03-28 |
2006-10-26 |
ファーマセット，インク． |
フラビウイルス科ウイルス感染の治療のための化合物
|
|
WO2005018330A1
(en)
*
|
2003-08-18 |
2005-03-03 |
Pharmasset, Inc. |
Dosing regimen for flaviviridae therapy
|
|
US20070042352A1
(en)
*
|
2003-08-18 |
2007-02-22 |
Dawn Patricia Wooley |
Retroviral vector and cell-based assay for measuring the mutations rate of retroviruses employing same
|
|
AU2006222563A1
(en)
|
2005-03-08 |
2006-09-14 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
|
JP4516863B2
(ja)
*
|
2005-03-11 |
2010-08-04 |
株式会社ケンウッド |
音声合成装置、音声合成方法及びプログラム
|
|
WO2006107923A1
(en)
*
|
2005-04-05 |
2006-10-12 |
Boehringer Ingelheim International Gmbh |
Substituted benzylimidazoles useful for the treatment of inflammatory diseases
|
|
US7781576B2
(en)
*
|
2005-12-23 |
2010-08-24 |
Idenix Pharmaceuticals, Inc. |
Process for preparing a synthetic intermediate for preparation of branched nucleosides
|
|
EP1859690A1
(en)
|
2006-05-26 |
2007-11-28 |
Health Concern B.V. |
Premix for cholesterol lowering food products
|
|
WO2009043096A1
(en)
*
|
2007-10-05 |
2009-04-09 |
Arana Therapeutics (Vic) Pty Ltd |
Improved method for mutagenesis
|
|
RS53602B1
(sr)
*
|
2007-11-29 |
2015-02-27 |
Boehringer Ingelheim International Gmbh |
DERIVATI AMIDA 6,7-DIHIDRO-5H-IMIDAZO[1,2-α]IMIDAZOL-3-KARBOKSILNE KISELINE
|
|
JP5146785B2
(ja)
*
|
2008-07-24 |
2013-02-20 |
国立大学法人九州大学 |
酵素基質修飾ヌクレオシド三リン酸誘導体
|
|
JP4621926B2
(ja)
*
|
2008-07-24 |
2011-02-02 |
国立大学法人九州大学 |
酵素基質修飾ヌクレオシド三リン酸、核酸プローブ、マルチラベル化核酸プローブ、マルチラベル化核酸プローブの製造方法および標的核酸の検出方法
|
|
WO2010108140A1
(en)
*
|
2009-03-20 |
2010-09-23 |
Alios Biopharma, Inc. |
Substituted nucleoside and nucleotide analogs
|
|
BRPI1012581A2
(pt)
|
2009-06-02 |
2016-03-29 |
Boehringer Ingelheim Int |
derivados de amidas de ácido 6, 7-di-hidro-5h-imidazol[1,2-a]imidazol-3-carboxílico
|
|
US8481750B2
(en)
|
2009-06-02 |
2013-07-09 |
Boehringer Ingelheim International Gmbh |
Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amides
|
|
JP5704481B2
(ja)
*
|
2010-01-22 |
2015-04-22 |
国立大学法人九州大学 |
核酸検出用キット
|
|
WO2012040127A1
(en)
|
2010-09-22 |
2012-03-29 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
|
EP2697242B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
EP2696679B1
(en)
|
2011-04-13 |
2017-08-02 |
Merck Sharp & Dohme Corp. |
2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2012142085A1
(en)
|
2011-04-13 |
2012-10-18 |
Merck Sharp & Dohme Corp. |
2'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013009737A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
|
|
WO2013009735A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
EP2794630A4
(en)
|
2011-12-22 |
2015-04-01 |
Alios Biopharma Inc |
SUBSTITUTED PHOSPHORTHIOAT NUCLEOTIDE ANALOGUE
|
|
NZ631601A
(en)
|
2012-03-21 |
2016-06-24 |
Alios Biopharma Inc |
Solid forms of a thiophosphoramidate nucleotide prodrug
|
|
NZ630805A
(en)
|
2012-03-22 |
2016-01-29 |
Alios Biopharma Inc |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
US10278984B2
(en)
*
|
2014-05-02 |
2019-05-07 |
Nitor Therapeutics |
Guanosine as an immune potentiator mediated through toll receptors
|
|
US12227769B2
(en)
|
2018-10-19 |
2025-02-18 |
The University Of Chicago |
Methods and compositions for treating negative-sense single-stranded RNA virus
|