NZ507848A - Method of increasing the mutation rate of a virus in a non-human by administering an RNA nucleoside analogue to a virally infected cell - Google Patents
Method of increasing the mutation rate of a virus in a non-human by administering an RNA nucleoside analogue to a virally infected cellInfo
- Publication number
- NZ507848A NZ507848A NZ507848A NZ50784897A NZ507848A NZ 507848 A NZ507848 A NZ 507848A NZ 507848 A NZ507848 A NZ 507848A NZ 50784897 A NZ50784897 A NZ 50784897A NZ 507848 A NZ507848 A NZ 507848A
- Authority
- NZ
- New Zealand
- Prior art keywords
- rna
- virus
- analog
- nucleotide
- viral
- Prior art date
Links
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2940496P | 1996-10-28 | 1996-10-28 | |
| US4053597P | 1997-02-27 | 1997-02-27 |
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| NZ507848A true NZ507848A (en) | 2005-01-28 |
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| NZ33500097A NZ335000A (en) | 1996-10-28 | 1997-10-27 | Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA |
| NZ507848A NZ507848A (en) | 1996-10-28 | 1997-10-27 | Method of increasing the mutation rate of a virus in a non-human by administering an RNA nucleoside analogue to a virally infected cell |
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| NZ33500097A NZ335000A (en) | 1996-10-28 | 1997-10-27 | Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA |
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| EP (1) | EP0948256A4 (enExample) |
| JP (1) | JP2001525797A (enExample) |
| AU (1) | AU740916B2 (enExample) |
| CA (1) | CA2269213A1 (enExample) |
| NZ (2) | NZ335000A (enExample) |
| WO (1) | WO1998018324A1 (enExample) |
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| EP0948256A4 (en) * | 1996-10-28 | 2007-10-24 | Univ Washington | INDUCTION OF VIRAL MUTATIONS BY INTRODUCTION TO ERROR-CODED RIBONUCLEOSIDE ANALOGUES IN VIRAL RNA |
| US6887707B2 (en) * | 1996-10-28 | 2005-05-03 | University Of Washington | Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA |
| US6423695B1 (en) * | 1998-01-13 | 2002-07-23 | Ribapharm, Inc. | Cytokine related treatments of disease |
| CA2368674A1 (en) * | 1999-03-26 | 2000-10-05 | Walter Reed Army Institute Of Research | Multivalent dengue virus vaccine |
| AU8038400A (en) * | 1999-09-09 | 2001-04-10 | Zymetx, Inc. | Method of treatment of influenza |
| AU7938900A (en) * | 1999-10-27 | 2001-05-08 | Cytos Biotechnology Ag | Method for creating divergent populations of nucleic acid molecules and proteins |
| US7638496B2 (en) | 2000-02-15 | 2009-12-29 | Valeant Pharmaceuticals North America | Nucleoside analogs with carboxamidine modified monocyclic base |
| SK11922002A3 (sk) | 2000-02-18 | 2003-06-03 | Shire Biochem Inc. | Použitie analógov nukleozidov na liečenie alebo prevenciu infekcií spôsobených flavivírusom |
| MY164523A (en) * | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
| CZ301182B6 (cs) * | 2000-05-26 | 2009-12-02 | Idenix (Cayman) Limited | Použití nukleosidových derivátu pro výrobu farmaceutických prostredku pro lécení infekcí vyvolaných flaviviry a pestiviry |
| DK2251015T3 (da) * | 2000-10-18 | 2013-05-13 | Gilead Pharmasset Llc | Modificerede nukleotider til behandling af virusinfektioner og abnorm celleproliferation |
| SK286630B6 (sk) * | 2001-01-22 | 2009-02-05 | Merck & Co., Inc. | Nukleozidové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie |
| US8481712B2 (en) | 2001-01-22 | 2013-07-09 | Merck Sharp & Dohme Corp. | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase |
| AU2002252183A1 (en) * | 2001-03-06 | 2002-09-19 | Biocryst Pharmaceuticals, Inc. | Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases |
| JP2005505536A (ja) * | 2001-08-24 | 2005-02-24 | コローニス ファーマシューティカルズ インコーポレイテッド | ウイルス疾患の治療のための変異原性ヌクレオシド類似体 |
| US20040006002A1 (en) * | 2001-09-28 | 2004-01-08 | Jean-Pierre Sommadossi | Methods and compositions for treating flaviviruses and pestiviruses using 4'-modified nucleoside |
| US7049303B2 (en) * | 2001-11-07 | 2006-05-23 | Medical Research Council | Inhibition of viruses |
| US20040138170A1 (en) * | 2002-03-06 | 2004-07-15 | Montgomery John A. | Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases |
| NZ537662A (en) * | 2002-06-28 | 2007-10-26 | Idenix Cayman Ltd | 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4072574A (en) * | 1976-07-30 | 1978-02-07 | The Institute For Cancer Research | System for in vitro assay for mutagenicity and/or carcinogenicity of chemicals or other exogenous agents |
| US5512431A (en) * | 1994-06-29 | 1996-04-30 | Darwin Molecular Corporation | Methods of screening for nucleoside analogs that are incorporated by HIV reverse transcriptase and cause incorrect base pairing |
| EP0948256A4 (en) * | 1996-10-28 | 2007-10-24 | Univ Washington | INDUCTION OF VIRAL MUTATIONS BY INTRODUCTION TO ERROR-CODED RIBONUCLEOSIDE ANALOGUES IN VIRAL RNA |
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1997
- 1997-10-27 EP EP97913882A patent/EP0948256A4/en not_active Withdrawn
- 1997-10-27 NZ NZ33500097A patent/NZ335000A/xx unknown
- 1997-10-27 US US08/958,065 patent/US6063628A/en not_active Expired - Lifetime
- 1997-10-27 WO PCT/US1997/019670 patent/WO1998018324A1/en not_active Ceased
- 1997-10-27 JP JP52073998A patent/JP2001525797A/ja active Pending
- 1997-10-27 NZ NZ507848A patent/NZ507848A/en not_active IP Right Cessation
- 1997-10-27 CA CA 2269213 patent/CA2269213A1/en not_active Abandoned
- 1997-10-27 AU AU50959/98A patent/AU740916B2/en not_active Ceased
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| WO1998018324A1 (en) | 1998-05-07 |
| CA2269213A1 (en) | 1998-05-07 |
| NZ335000A (en) | 2000-12-22 |
| US6063628A (en) | 2000-05-16 |
| JP2001525797A (ja) | 2001-12-11 |
| EP0948256A4 (en) | 2007-10-24 |
| EP0948256A1 (en) | 1999-10-13 |
| AU5095998A (en) | 1998-05-22 |
| AU740916B2 (en) | 2001-11-15 |
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