JP2001524516A - Ｃｙｐ２ａ酵素に依存した治療及び診断方法 - Google Patents
Ｃｙｐ２ａ酵素に依存した治療及び診断方法Info
- Publication number
- JP2001524516A JP2001524516A JP2000522905A JP2000522905A JP2001524516A JP 2001524516 A JP2001524516 A JP 2001524516A JP 2000522905 A JP2000522905 A JP 2000522905A JP 2000522905 A JP2000522905 A JP 2000522905A JP 2001524516 A JP2001524516 A JP 2001524516A
- Authority
- JP
- Japan
- Prior art keywords
- cyp2a6
- nicotine
- cyp2a
- individual
- substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Addiction (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6702197P | 1997-12-01 | 1997-12-01 | |
| US6702097P | 1997-12-01 | 1997-12-01 | |
| US60/067,020 | 1997-12-01 | ||
| US60/067,021 | 1997-12-01 | ||
| US8484798P | 1998-05-08 | 1998-05-08 | |
| US60/084,847 | 1998-05-08 | ||
| US10739298P | 1998-11-06 | 1998-11-06 | |
| US60/107,392 | 1998-11-06 | ||
| PCT/CA1998/001093 WO1999027919A2 (en) | 1997-07-17 | 1998-12-01 | Cyp2a enzymes and their use in therapeutic and diagnostic methods |
Publications (2)
| Publication Number | Publication Date |
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| JP2001524516A true JP2001524516A (ja) | 2001-12-04 |
| JP2001524516A5 JP2001524516A5 (enExample) | 2005-11-17 |
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| JP2000522905A Pending JP2001524516A (ja) | 1997-12-01 | 1998-12-01 | Ｃｙｐ２ａ酵素に依存した治療及び診断方法 |
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| PT (1) | PT1033979E (enExample) |
| WO (1) | WO1999027919A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2010173973A (ja) * | 2009-01-30 | 2010-08-12 | Kinki Univ | Ｃｙｐ２ａ６阻害剤及びｃｙｐ２ａ６阻害活性物質のスクリーニング方法 |
Families Citing this family (11)
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| SE9900490D0 (sv) * | 1999-02-15 | 1999-02-15 | A & Science Invest Ab | Diagnostic agent and method |
| GB9927806D0 (en) * | 1999-11-24 | 2000-01-26 | Isis Innovation | Genetic indicators of tobacco consumption |
| US6492115B1 (en) | 2000-06-02 | 2002-12-10 | Dna Sciences Laboratories, Inc. | Genetic typing of the human cytochrome P450 2A6 gene and related materials and methods |
| US8688385B2 (en) * | 2003-02-20 | 2014-04-01 | Mayo Foundation For Medical Education And Research | Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype |
| CN1308462C (zh) * | 2003-09-22 | 2007-04-04 | 周宏灏 | 个体化用药基因型诊断芯片及其制造方法和应用方法 |
| KR100829122B1 (ko) * | 2006-12-05 | 2008-05-13 | 한국과학기술연구원 | 당귀 추출물 또는 이로부터 분리한 쿠마린계 화합물을 유효성분으로 함유하는 폐암 예방용 조성물 |
| EP2031072A1 (en) * | 2007-08-27 | 2009-03-04 | Andreas Ziegler | Method for in-vitro diagnosing a predisposition to smoking and a pharmaceutical composition for treating tobacco abuse |
| CN104004852B (zh) * | 2014-06-17 | 2015-12-02 | 陕西佰美基因股份有限公司 | 一种基于荧光定量pcr检测cyp2a6全基因缺失的方法 |
| EP3157519B1 (en) * | 2014-06-19 | 2021-05-12 | Immunolight, LLC | Methods and systems for treating cell proliferation disorders with psoralen derivatives |
| EP3207924A1 (de) | 2016-02-17 | 2017-08-23 | Flaxan GmbH & Co. KG | Pharmazeutische zubereitung zur hemmung humaner cyp-enzyme |
| CN116183779B (zh) * | 2023-04-18 | 2025-01-24 | 云南省烟草农业科学研究院 | 基于一步净化和液相色谱-串联质谱的烟气中TSNAs测定方法 |
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| RU2066998C1 (ru) * | 1992-06-25 | 1996-09-27 | Валерий Иванович Вольвич | Способ получения средства для лечения вирусного гепатита а |
| GB2303853B (en) * | 1994-06-16 | 1998-12-23 | Us Health | Variant alleles in cytochrome P450 expressing enzymes involved in metabolic processes |
| DE19646977A1 (de) * | 1995-09-29 | 1998-01-15 | Schwabe Willmar Gmbh & Co | Stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und pharmazeutische Zubereitungen |
| AU742628B2 (en) † | 1996-07-17 | 2002-01-10 | Nicogen Inc. | Methods for regulating nicotine metabolism |
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- 1998-12-01 ES ES98956735T patent/ES2273441T5/es not_active Expired - Lifetime
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- 1998-12-01 BR BR9815128-2A patent/BR9815128A/pt not_active Application Discontinuation
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- 1998-12-01 DE DE69835534T patent/DE69835534T3/de not_active Expired - Lifetime
- 1998-12-01 JP JP2000522905A patent/JP2001524516A/ja active Pending
- 1998-12-01 WO PCT/CA1998/001093 patent/WO1999027919A2/en not_active Ceased
- 1998-12-01 CA CA002312851A patent/CA2312851A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010173973A (ja) * | 2009-01-30 | 2010-08-12 | Kinki Univ | Ｃｙｐ２ａ６阻害剤及びｃｙｐ２ａ６阻害活性物質のスクリーニング方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2312851A1 (en) | 1999-06-10 |
| AU1328699A (en) | 1999-06-16 |
| CN100362995C (zh) | 2008-01-23 |
| AU762671B2 (en) | 2003-07-03 |
| DE69835534T3 (de) | 2010-09-23 |
| DE69835534T2 (de) | 2007-08-09 |
| WO1999027919A2 (en) | 1999-06-10 |
| NZ505439A (en) | 2005-02-25 |
| ES2273441T5 (es) | 2010-06-28 |
| EP1033979B9 (en) | 2007-02-28 |
| DE69835534D1 (de) | 2006-09-21 |
| ES2273441T3 (es) | 2007-05-01 |
| EP1033979A2 (en) | 2000-09-13 |
| EP1033979B1 (en) | 2006-08-09 |
| WO1999027919A3 (en) | 1999-08-12 |
| BR9815128A (pt) | 2000-10-10 |
| EP1033979B2 (en) | 2010-02-24 |
| AU762671C (en) | 2004-11-18 |
| CN1299276A (zh) | 2001-06-13 |
| ATE335484T1 (de) | 2006-09-15 |
| PT1033979E (pt) | 2006-12-29 |
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