JP2001521889A - 早期分娩の治療及び予防中における胎児動脈管の維持にシクロオキシゲナーゼ−２阻害剤を使用する方法 - Google Patents

早期分娩の治療及び予防中における胎児動脈管の維持にシクロオキシゲナーゼ−２阻害剤を使用する方法

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Publication number
JP2001521889A
JP2001521889A JP2000518654A JP2000518654A JP2001521889A JP 2001521889 A JP2001521889 A JP 2001521889A JP 2000518654 A JP2000518654 A JP 2000518654A JP 2000518654 A JP2000518654 A JP 2000518654A JP 2001521889 A JP2001521889 A JP 2001521889A
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JP
Japan
Prior art keywords
benzenesulfonamide
pyrazol
trifluoromethyl
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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JP2000518654A
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English (en)
Japanese (ja)
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JP2001521889A5 (enExample
Inventor
ニードルマン，フィリップ
マスファーラー，ジェイム
Original Assignee
ジー・ディー・サール・アンド・カンパニー
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Publication of JP2001521889A publication Critical patent/JP2001521889A/ja
Publication of JP2001521889A5 publication Critical patent/JP2001521889A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2000518654A 1997-10-31 1998-10-27 早期分娩の治療及び予防中における胎児動脈管の維持にシクロオキシゲナーゼ−２阻害剤を使用する方法 Withdrawn JP2001521889A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6388997P 1997-10-31 1997-10-31
US60/063,889 1997-10-31
PCT/US1998/022246 WO1999022720A2 (en) 1997-10-31 1998-10-27 Selective cyclooxygenase-2 inhibitors against premature labor

Publications (2)

Publication Number Publication Date
JP2001521889A true JP2001521889A (ja) 2001-11-13
JP2001521889A5 JP2001521889A5 (enExample) 2006-01-05

Family

ID=22052179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000518654A Withdrawn JP2001521889A (ja) 1997-10-31 1998-10-27 早期分娩の治療及び予防中における胎児動脈管の維持にシクロオキシゲナーゼ−２阻害剤を使用する方法

Country Status (9)

Country Link
EP (1) EP1027048A2 (enExample)
JP (1) JP2001521889A (enExample)
AR (1) AR014000A1 (enExample)
AU (1) AU758566B2 (enExample)
BR (1) BR9813164A (enExample)
CA (1) CA2308639A1 (enExample)
TW (2) TW200404535A (enExample)
WO (1) WO1999022720A2 (enExample)
ZA (1) ZA989876B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1617716A (zh) * 2000-06-08 2005-05-18 德克萨斯系统大学评议会 杂环衍生物与使用方法
ES2275218T3 (es) 2003-05-07 2007-06-01 Osteologix A/S Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6718494A (en) * 1993-05-13 1994-12-12 Merck Frosst Canada Inc. 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
EP0889724A1 (en) * 1996-02-27 1999-01-13 Rpms Technology Limited Cox-2 selective inhibitors for managing labour and uterine contractions
US5677318A (en) * 1996-07-11 1997-10-14 Merck Frosst Canada, Inc. Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents

Also Published As

Publication number Publication date
TW577739B (en) 2004-03-01
EP1027048A2 (en) 2000-08-16
AU1192699A (en) 1999-05-24
WO1999022720A2 (en) 1999-05-14
WO1999022720A3 (en) 1999-08-26
AR014000A1 (es) 2001-01-31
TW200404535A (en) 2004-04-01
CA2308639A1 (en) 1999-05-14
ZA989876B (en) 1999-10-29
AU758566B2 (en) 2003-03-27
BR9813164A (pt) 2000-08-22

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