BR9813164A - Método de uso de inibidores da ciclooxigenase-2 na manutenção do ducto arterial fetal durante o tratamento e prevenção de dores prematuras de parto - Google Patents

Método de uso de inibidores da ciclooxigenase-2 na manutenção do ducto arterial fetal durante o tratamento e prevenção de dores prematuras de parto

Info

Publication number
BR9813164A
BR9813164A BR9813164-8A BR9813164A BR9813164A BR 9813164 A BR9813164 A BR 9813164A BR 9813164 A BR9813164 A BR 9813164A BR 9813164 A BR9813164 A BR 9813164A
Authority
BR
Brazil
Prior art keywords
inhibitors
cyclooxygenase
premature labor
maintain
labor pains
Prior art date
Application number
BR9813164-8A
Other languages
English (en)
Inventor
Philip Needleman
Jaime Masferrer
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of BR9813164A publication Critical patent/BR9813164A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/06Anti-spasmodics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Patente de Invenção: <B>"MéTODO DE USO DE INIBIDORES DA CICLOOXIGENASE-2 NA MANUTENçãO DO DUCTO ARTERIAL FETAL DURANTE O TRATAMENTO E PREVENçãO DE DORES PREMATURAS DE PARTO"<D>. A presente invenção refere-se ao uso de inibidores de ciclooxigenase-2 ou derivados dos mesmos na prevenção e tratamento de dores prematuras de parto. Em particular, a invenção descreve o método de prevenção e tratamento de dores prematuras de parto em um indivíduo, o referido método compreendendo o tratamento do indivíduo com uma quantidade terapeuticamente eficaz de um composto da fórmula (I), em que R¹, R² e R³ são descritos na especificação.
BR9813164-8A 1997-10-31 1998-10-27 Método de uso de inibidores da ciclooxigenase-2 na manutenção do ducto arterial fetal durante o tratamento e prevenção de dores prematuras de parto BR9813164A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6388997P 1997-10-31 1997-10-31
PCT/US1998/022246 WO1999022720A2 (en) 1997-10-31 1998-10-27 Selective cyclooxygenase-2 inhibitors against premature labor

Publications (1)

Publication Number Publication Date
BR9813164A true BR9813164A (pt) 2000-08-22

Family

ID=22052179

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9813164-8A BR9813164A (pt) 1997-10-31 1998-10-27 Método de uso de inibidores da ciclooxigenase-2 na manutenção do ducto arterial fetal durante o tratamento e prevenção de dores prematuras de parto

Country Status (9)

Country Link
EP (1) EP1027048A2 (pt)
JP (1) JP2001521889A (pt)
AR (1) AR014000A1 (pt)
AU (1) AU758566B2 (pt)
BR (1) BR9813164A (pt)
CA (1) CA2308639A1 (pt)
TW (2) TW577739B (pt)
WO (1) WO1999022720A2 (pt)
ZA (1) ZA989876B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020188016A9 (en) * 2000-06-08 2002-12-12 Peterson Johnny W. Heterocycle derivatives and methods of use
ES2275218T3 (es) 2003-05-07 2007-06-01 Osteologix A/S Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2161789A1 (en) * 1993-05-13 1994-11-24 Jacques Yves Gauthier 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
EP0889724A1 (en) * 1996-02-27 1999-01-13 Rpms Technology Limited Cox-2 selective inhibitors for managing labour and uterine contractions
US5677318A (en) * 1996-07-11 1997-10-14 Merck Frosst Canada, Inc. Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents

Also Published As

Publication number Publication date
TW577739B (en) 2004-03-01
EP1027048A2 (en) 2000-08-16
JP2001521889A (ja) 2001-11-13
AU1192699A (en) 1999-05-24
ZA989876B (en) 1999-10-29
WO1999022720A3 (en) 1999-08-26
CA2308639A1 (en) 1999-05-14
TW200404535A (en) 2004-04-01
AU758566B2 (en) 2003-03-27
WO1999022720A2 (en) 1999-05-14
AR014000A1 (es) 2001-01-31

Similar Documents

Publication Publication Date Title
ES2160707T3 (es) Composiciones que comprenden agentes deteriorantes del adn y p53.
BR9812484A (pt) Terapia combinada para erradicação de hcv-rna detectável em pacientes com infecção crÈnica por hepatite c
DE69329856D1 (de) Ester derivate von 4-aza-steroiden
FI971969A0 (fi) Peräpukamien hoitoon tarkoitettuja koostumuksia ja käyttömenetelmä
BR9712314A (pt) Método de uso de inibidores de ciclooxigenase-2 no tratamento e prevenção de neoplasia
MX9700237A (es) Combinaciones inhibidoras de proteasa retroviral.
BR0014384A (pt) Compostos para o tratamento da isquémia
ATE249421T1 (de) Inhibitoren der alpha4-beta1 vermittelten zelladhäsion
FI953180A0 (fi) Sokeritaudin komplikaatioiden hoitamiseen tarkoitetut koostumukset
ES2191069T3 (es) Diaril-2-(5h)-furanonas como inhibidores de cox-2.
BR0001468A (pt) ácidos dioxiciclopentil hidroxânicos
PT705100E (pt) Guanidinas substituidas terapeuticas
ATE316962T1 (de) Pyrimidin-derivate als selective inhibitoren von cox-2
PT1144365E (pt) Inibidores da adesao de celulas mediada por alfa4beta1
BR9813319A (pt) Composto, composição farmacêutica para tratamento de infecções bacterianas, e, processos para tratar infecções bacterianas e para preparar um composto
BR0209128A (pt) Compostos, composições farmacêuticas, métodos para o tratamento de dores, métodos para a modulação de uma resposta farmacológica e usos de compostos
DE69405919D1 (de) Zusammensetzungen zur Behandlung von Keratinfasern
BR9712141A (pt) Aplicação de 1-hifróxi-2-piridonas para tratamento de infecções cutâneas.
IL143594A0 (en) Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases
BR9809678A (pt) Derivados de triptolìdeo úteis no tratamento de doenças autoimunes
KR950016760A (ko) 치질 치료제
BR9611472A (pt) Compostos de di-terc-butilfenol contendo enxofre úteis como agentes antiinflamatórios
FI961380A (fi) Koostumuksia virusten aiheuttamien kasvainten ehkäisemiseksi ja hoitamiseksi
BR9813164A (pt) Método de uso de inibidores da ciclooxigenase-2 na manutenção do ducto arterial fetal durante o tratamento e prevenção de dores prematuras de parto
DK0986393T3 (da) Anvendelse af et nitroxid eller et prodrug heraf ved profylaktisk og terapeutisk behandling af cancer

Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI.